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  1. Article: [Research development in the anti-influenza drugs in children].

    Liu, X Y / Jiang, R M

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2019  Volume 57, Issue 4, Page(s) 313–316

    Language Chinese
    Publishing date 2019-04-01
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.issn.0578-1310.2019.04.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Primary hypertrophic osteoarthropathy with renal hypokalemia: a case report].

    Jiang, R M / Li, J / Wang, Z Q / Shen, J F / Niu, M

    Zhonghua nei ke za zhi

    2020  Volume 59, Issue 9, Page(s) 720–723

    MeSH term(s) Diagnosis, Differential ; Humans ; Hypokalemia ; Kidney ; Osteoarthropathy, Primary Hypertrophic
    Language Chinese
    Publishing date 2020-08-19
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20190918-00637
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Clinical features of 9 cases of Brucella endocarditis].

    Su, Y J / Dong, Q / Han, X T / Wang, J J / Tian, D / Jiang, R M

    Zhonghua xin xue guan bing za zhi

    2020  Volume 48, Issue 2, Page(s) 142–147

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adult ; Aged ; Animals ; Brucella ; Brucellosis ; Cattle ; China ; Endocarditis, Bacterial ; Heart Valve Prosthesis ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Sheep ; Treatment Outcome
    Language Chinese
    Publishing date 2020-03-02
    Publishing country China
    Document type Journal Article
    ZDB-ID 603425-1
    ISSN 0253-3758
    ISSN 0253-3758
    DOI 10.3760/cma.j.issn.0253-3758.2020.02.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Recurrence and influencing factors of diabetic foot ulcer in patients with type 2 diabetes mellitus].

    Shen, J F / Jiang, R M / Wang, Z Q / Li, M / Li, J / Xie, S Y / Kang, J J

    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

    2020  Volume 36, Issue 10, Page(s) 947–952

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adult ; Aged ; Amputation ; Case-Control Studies ; Diabetes Mellitus, Type 2/complications ; Diabetic Foot/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors
    Language Chinese
    Publishing date 2020-10-22
    Publishing country China
    Document type Journal Article
    ZDB-ID 2229222-6
    ISSN 1009-2587
    ISSN 1009-2587
    DOI 10.3760/cma.j.cn501120-20190726-00315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Deltonin induced both apoptosis and autophagy in head and neck squamous carcinoma FaDu cell.

    Xie, Y L / Fan, M / Jiang, R M / Wang, Z L / Li, Y

    Neoplasma

    2015  Volume 62, Issue 3, Page(s) 419–431

    Abstract: For decades, despite the advancement of medical science, the prognosis of head and neck squamous cell carcinoma (HNSCC), has not improved. Deltonin is one of the major active components of Dioscorea Zingiberensis Wright that has been used for anthrax, ... ...

    Abstract For decades, despite the advancement of medical science, the prognosis of head and neck squamous cell carcinoma (HNSCC), has not improved. Deltonin is one of the major active components of Dioscorea Zingiberensis Wright that has been used for anthrax, rheumatic heart disease, rheumatoid arthritis etc. By employing HNSCC FaDu cell and normal human epidermal keratinocyte, we investigate deltonin efficacy and associated mechanism in both cell culture and nude mice xenografts. Deltonin treatment selectively prevents proliferation of FaDu cells by cell-cycle arrest and induction of apoptosis, via activating checkpoint kinase Chk1and Chk2 as well as caspases 8, 9 and 3. Meanwhile, we found that treatment with deltonin induced autophagy, which played a protective role against deltonin-induced apoptosis. Further studies revealed that deltonin activated autophagy by Akt-mTOR signaling. Additionally, xenograft model showed that administration of deltonin significantly inhibited tumor growth and prolonged survival of tumor bearing mice. Our studies suggested that deltonin might be a potential chemotherapeutic agent against HNSCC, which might contribute to clinical application and pharmacological study of deltonin in future anti-cancer research.
    Language English
    Publishing date 2015
    Publishing country Slovakia
    Document type Journal Article
    ZDB-ID 415445-9
    ISSN 0028-2685
    ISSN 0028-2685
    DOI 10.4149/neo_2015_050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [2019 novel coronavirus: appropriate rather than undue protection].

    Jiang, L / Li, L Y / Wu, A H / Jiang, R M / Zheng, R Q / Li, X Y / Sang, L / Pan, C / Zheng, X / Zhong, M / Zhang, W / Guan, X D / Tong, Z H / Du, B / Qiu, H B

    Zhonghua nei ke za zhi

    2020  Volume 59, Issue 9, Page(s) 662–664

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language Chinese
    Publishing date 2020-08-24
    Publishing country China
    Document type Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20200303-00172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [2019 Novel Coronavirus: Appropriate Rather than Undue Protection]

    Jiang, L / Li, L Y / Wu, A H / Jiang, R M / Zheng, R Q / Li, X Y / Sang, L / Pan, C / Zheng, X / Zhong, M / Zhang, W / Guan, X D / Tong, Z H / Du, B / Qiu, H B

    Zhonghua Nei Ke Za Zhi

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #729665
    Database COVID19

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