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  1. Book ; Online ; E-Book: Nature through a hospital window

    Jiang, Shan

    the therapeutic benefits of landscape in architectural design

    (Health and the built environment series)

    2022  

    Abstract: Adopting an evidence-based approach, this book uses two state-of-the-art experimental studies to explore nature's therapeutic benefits in healthcare environments, emphasizing how windows and transparent spaces can strengthen people-nature interactions. ... ...

    Title variant Therapeutic benefits of landscape in architectural design
    Author's details Shan Jiang
    Series title Health and the built environment series
    Abstract "Adopting an evidence-based approach, this book uses two state-of-the-art experimental studies to explore nature's therapeutic benefits in healthcare environments, emphasizing how windows and transparent spaces can strengthen people-nature interactions. High-quality, supportive, and patient-centred healthcare environments are a key priority for healthcare designers worldwide, with ageing populations creating a demand for remodelled and updated facilities. The first study demonstrates individual psychophysiological responses, moods, and preferences in simulated hospital waiting areas with different levels of visual access to nature through windows, while the second experiment uses cutting-edge immersive virtual reality techniques to explore how gardens and nature views impact people's spatial cognition, wayfinding behaviors, and experience when navigating hospitals. Through these studies and discussions drawing on architectural theory and history, the book highlights the important benefits of having access to nature from hospital interiors. This concise volume will appeal to academics and designers interested in therapeutic landscapes and healthcare architecture"--
    Keywords Architecture/Health aspects ; Health facilities/Design and construction ; Nature/Therapeutic use.
    Subject code 725/.52
    Language English
    Size 1 online resource (xvii, 185 pages) :, illustrations, maps, plans
    Publisher Routledge
    Publishing place Milton Park, Abingdon, Oxon ; New York, NY
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-00-312218-3 ; 1-000-55235-7 ; 1-000-55239-X ; 1-003-12218-3 ; 9780367641054 ; 978-1-00-312218-0 ; 978-1-000-55235-5 ; 978-1-000-55239-3 ; 978-1-003-12218-0 ; 0367641054
    DOI 10.4324/9781003122180
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: A Scoping Review of Global Guidelines for the Disclosure of Secondary Genomic Findings to Inform the Establishment of Guidelines in China.

    Jiang, Shan

    China CDC weekly

    2022  Volume 4, Issue 32, Page(s) 697–705

    Abstract: The detection and disclosure of secondary findings (SFs) is a preventive strategy for medically-actionable hereditary health conditions. Some countries have guidelines on management and disclosure of SFs, while others avoid detection and disclosure of ... ...

    Abstract The detection and disclosure of secondary findings (SFs) is a preventive strategy for medically-actionable hereditary health conditions. Some countries have guidelines on management and disclosure of SFs, while others avoid detection and disclosure of SFs. This study is a review of clinical guidelines from six countries and the European Union to identify similarities and differences among SF guidelines. Evidence from this review supports harmonization of guidelines across countries to promote broad international collaborations on genomics and to benefit precision medicine. This study can serve as a reference for development of SF management guidelines in China by contributing evidence from other countries to the ethical and methodological challenges under debate.
    Language English
    Publishing date 2022-08-25
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2022.146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Microstructure and deformation mechanism of TA2 titanium deformed by rotary forging.

    Jiang, Shan

    Science progress

    2021  Volume 104, Issue 3, Page(s) 368504211031754

    Abstract: Rotary forging was conducted for TA2 titanium samples with initial forming temperatures ranging from room temperature to 923 K. The microstructure of the samples was examined by using electron back-scattered diffraction and X-ray diffraction. The results ...

    Abstract Rotary forging was conducted for TA2 titanium samples with initial forming temperatures ranging from room temperature to 923 K. The microstructure of the samples was examined by using electron back-scattered diffraction and X-ray diffraction. The results indicate that rotary forging remarkably enhanced the formability of TA2 titanium and took a notable grain refinement effect over the whole temperature range. The theoretical calculation results indicate that enough working heat was generated during the early deformation stage to raise the temperature of the sample to above the dynamic recrystallization temperature. The deformation of titanium during rotary forging can be roughly divided into two stages as dislocation slip stage and the dynamic recrystallization stage.
    Language English
    Publishing date 2021-09-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 128412-5
    ISSN 2047-7163 ; 0036-8504 ; 0302-1785
    ISSN (online) 2047-7163
    ISSN 0036-8504 ; 0302-1785
    DOI 10.1177/00368504211031754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Exploration of the shared gene signatures and biological mechanisms between ischemia-reperfusion injury and antibody-mediated rejection in renal transplantation.

    Jiang, Shan / Su, Hua

    Transplant immunology

    2024  Volume 83, Page(s) 102001

    Abstract: Background: Antibody-mediated rejection (ABMR) plays a crucial role in graft loss during allogeneic renal transplantation. In renal transplantation, ischemia-reperfusion injury (IRI) is unavoidable, serves as a major contributor to acute rejection, and ... ...

    Abstract Background: Antibody-mediated rejection (ABMR) plays a crucial role in graft loss during allogeneic renal transplantation. In renal transplantation, ischemia-reperfusion injury (IRI) is unavoidable, serves as a major contributor to acute rejection, and is linked to graft loss. However, the mechanisms underlying IRI and ABMR are unclear. Therefore, this study aimed to investigate the shared genetic characteristics and biological mechanisms between IRI and ABMR.
    Methods: Gene expressions for IRI (GSE43974) and ABMR (GSE129166 and GSE36059) were retrieved from the Gene Expression Omnibus database. The shared differentially expressed genes (DEGs) of IRI and ABMR were identified, and subsequent functional enrichment analysis was performed. Immune cell infiltration in ABMR and its relationship with the shared DEGs were investigated using the CIBERSORT method. Random forest analysis, a protein-protein interaction network, and Cytoscape were used to screen hub genes, which were subsequently subjected to gene set enrichment analysis, miRNA prediction, and transcription factors analysis. The survival analysis was performed through Kaplan-Meier curves. Finally, drug compound prediction was performed on the shared DEGs using the Drug Signature Database.
    Results: Overall, 27 shared DEGs were identified between the renal IRI and ABMR groups. Among these, 24 genes exhibited increased co-expression, whereas none showed decreased co-expression. The shared DEGs were primarily enriched in the inflammation signaling pathways. Notably, CD4 memory T cells were identified as potential critical mediators of IRI, leading to ABMR. Tumor necrosis factor alpha-induced protein 3 (TNFAIP3), interferon regulatory factor 1 (IRF1), and early growth response 2 (EGR2) were identified as key components in the potential mechanism that link IRI and ABMR. Patients undergoing renal transplantation with higher expression levels of TNFAIP3, IRF1, and EGR2 exhibited decreased survival rates compared to those with lower expression levels.
    Conclusion: Inflammation is a key mechanism that links IRI and ABMR, with a potential role played by CD4 memory T cells. Furthermore, TNFAIP3, IRF1, and EGR2 are implicated in the underlying mechanism between IRI and ABMR.
    MeSH term(s) Humans ; Kidney Transplantation ; Kidney/pathology ; Antibodies/metabolism ; Reperfusion Injury/metabolism ; Inflammation/metabolism
    Chemical Substances Antibodies
    Language English
    Publishing date 2024-01-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1160846-8
    ISSN 1878-5492 ; 0966-3274
    ISSN (online) 1878-5492
    ISSN 0966-3274
    DOI 10.1016/j.trim.2024.102001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Positive Distractions and Play in the Public Spaces of Pediatric Healthcare Environments: A Literature Review.

    Jiang, Shan

    HERD

    2020  Volume 13, Issue 3, Page(s) 171–197

    Abstract: Background: A positive distraction is a significant environmental feature that introduces positive feelings by diverting attention from stress or anxious thoughts. Existing research has deemed the application of positive distractions in pediatric ... ...

    Abstract Background: A positive distraction is a significant environmental feature that introduces positive feelings by diverting attention from stress or anxious thoughts. Existing research has deemed the application of positive distractions in pediatric environments to be significant. This study investigated the essential positive distractions and the associated health benefits.
    Aims: The aims of this study were to validate and extend evidence on positive distractions and play opportunities in the design of the public spaces in pediatric healthcare environments, translate existing evidence into design suggestions, and identify research gaps in this realm.
    Methods: A four-phased literature review method was employed in the study, including literature search, literature screening and selection, literature appraisal, and thematic analysis and in-depth discussion. Eventually, 27 peer-reviewed publications were reviewed and discussed in detail.
    Results/conclusions: The gathered materials were grouped into six themes of positive distractions: (1) art and environmental aesthetics, (2) spatial arrangement and atrium, (3) considerations of socialization patterns, (4) play and interactive technologies, (5) sound and lighting interventions, and (6) access to nature. The research indicated that positive distractions in the pediatric healthcare environment provide a series of health benefits for patients, including improved behavioral and emotional well-being, reduced stress and anxiety, enhanced healthcare experience and satisfaction, and facilitated medical procedures and recovery. Yet significant research gaps emerged between positive distractions and play in garden spaces and spatial design to accommodate interactive technology and socialization in the public areas of pediatric healthcare environments. This study organized the understanding on the components of supportive environments and its outcomes for pediatric healthcare design.
    MeSH term(s) Art ; Child ; Facility Design and Construction ; Health Facility Environment ; Hospitals, Pediatric/standards ; Humans ; Interior Design and Furnishings ; Lighting ; Nature ; Noise ; Play and Playthings ; Social Interaction
    Language English
    Publishing date 2020-02-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2525547-2
    ISSN 2167-5112 ; 1937-5867
    ISSN (online) 2167-5112
    ISSN 1937-5867
    DOI 10.1177/1937586720901707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cellular crosstalk of mesangial cells and tubular epithelial cells in diabetic kidney disease.

    Jiang, Shan / Su, Hua

    Cell communication and signaling : CCS

    2023  Volume 21, Issue 1, Page(s) 288

    Abstract: Diabetic kidney disease (DKD) is a major cause of end-stage renal disease and imposes a heavy global economic burden; however, little is known about its complicated pathophysiology. Investigating the cellular crosstalk involved in DKD is a promising ... ...

    Abstract Diabetic kidney disease (DKD) is a major cause of end-stage renal disease and imposes a heavy global economic burden; however, little is known about its complicated pathophysiology. Investigating the cellular crosstalk involved in DKD is a promising avenue for gaining a better understanding of its pathogenesis. Nonetheless, the cellular crosstalk of podocytes and endothelial cells in DKD is better understood than that of mesangial cells (MCs) and renal tubular epithelial cells (TECs). As the significance of MCs and TECs in DKD pathophysiology has recently become more apparent, we reviewed the existing literature on the cellular crosstalk of MCs and TECs in the context of DKD to acquire a comprehensive understanding of their cellular communication. Insights into the complicated mechanisms underlying the pathophysiology of DKD would improve its early detection, care, and prognosis. Video Abstract.
    MeSH term(s) Humans ; Diabetic Nephropathies/pathology ; Mesangial Cells/pathology ; Endothelial Cells/pathology ; Epithelial Cells/pathology ; Podocytes/pathology ; Diabetes Mellitus/pathology
    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Video-Audio Media ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2126315-2
    ISSN 1478-811X ; 1478-811X
    ISSN (online) 1478-811X
    ISSN 1478-811X
    DOI 10.1186/s12964-023-01323-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Coordination-Induced Multivalent Self-Assembling Catalysts for Spectral Sensing Zn

    Li, Shuai-Bing / Shen, Jiang-Shan

    Inorganic chemistry

    2023  Volume 62, Issue 24, Page(s) 9454–9462

    Abstract: The introduction of signal amplification to molecular spectral sensing systems is an intriguing topic in supramolecular analytical chemistry. In this study, click chemistry was used to generate a triazole moiety to bridge with a long hydrophobic alkyl ... ...

    Abstract The introduction of signal amplification to molecular spectral sensing systems is an intriguing topic in supramolecular analytical chemistry. In this study, click chemistry was used to generate a triazole moiety to bridge with a long hydrophobic alkyl chain (C
    Language English
    Publishing date 2023-06-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.3c00545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Modulating Dual Fluorescence Emissions in Imine-Based Probes to Distinguish D

    Ji, Rui-Xue / Shen, Jiang-Shan

    The journal of physical chemistry. B

    2023  Volume 127, Issue 5, Page(s) 1229–1236

    Abstract: How to distinguish ... ...

    Abstract How to distinguish D
    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.2c08070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Deep Dual-Resolution Road Scene Segmentation Networks Based on Decoupled Dynamic Filter and Squeeze-Excitation Module.

    Ni, Hongyin / Jiang, Shan

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 16

    Abstract: Image semantic segmentation is an important part of automatic driving assistance technology. The complexity of road scenes and the real-time requirements of application scenes for segmentation algorithm are the challenges facing segmentation algorithms. ... ...

    Abstract Image semantic segmentation is an important part of automatic driving assistance technology. The complexity of road scenes and the real-time requirements of application scenes for segmentation algorithm are the challenges facing segmentation algorithms. In order to meet the above challenges, Deep Dual-resolution Road Scene Segmentation Networks based on Decoupled Dynamic Filter and Squeeze-Excitation (DDF&SE-DDRNet) are proposed in this paper. The proposed DDF&SE-DDRNet uses decoupled dynamic filter in each module to reduce the number of network parameters and enable the network to dynamically adjust the weight of each convolution kernel. We add the Squeeze-and-Excitation module to each module of DDF&SE-DDRNet so that the local feature map in the network can obtain global features to reduce the impact of image local interference on the segmentation result. The experimental results on the Cityscapes dataset show that the segmentation accuracy of DDF&SE-DDRNet is at least 2% higher than that of existing algorithms. Moreover, DDF&SE-DDRNet also has satisfactory inferring speed.
    Language English
    Publishing date 2023-08-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23167140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Enhancing Neonatal Intensive Care With Rapid Genome Sequencing.

    Jiang, Shan / Parkinson, Bonny / Gu, Yuanyuan

    JAMA network open

    2024  Volume 7, Issue 2, Page(s) e240097

    MeSH term(s) Humans ; Infant, Newborn ; Intensive Care, Neonatal ; Genome, Human ; Whole Genome Sequencing
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2024.0097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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