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Article: Effects of combined high pressure and enzymatic treatments on physicochemical and antioxidant properties of peanut proteins

Jiang, Yueming

Food Science & Nutrition, 7(4):1417-1425

2019

Abstract: Isolated peanut protein (PPI) dispersions were pretreated by high pressure at 100, 300, and 500 MPa prior to enzymatic hydrolysis with alkaline protease (Alcalase). The degree of hydrolysis (DH) was determined by the pH‐stat method, the hydrolysates ... ...

Abstract	Isolated peanut protein (PPI) dispersions were pretreated by high pressure at 100, 300, and 500 MPa prior to enzymatic hydrolysis with alkaline protease (Alcalase). The degree of hydrolysis (DH) was determined by the pH‐stat method, the hydrolysates profiles were analyzed by high‐performance liquid chromatography (HPLC), the molecular weight distribution (MWD) was analyzed by gel filtration chromatogram (GFC), and content of SH/S‐S and antioxidant activity of hydrolysates were evaluated. Results showed that HP pretreatment improved effectively the enzymatic hydrolysis of PPI, with an effective sequence of 300 > 100 > 500 MPa. However, no significant differences were observed in the peak pattern of HPLC profiles, but the peak times were earlier in HPLC profiles of the HP‐treated protein. GFC analysis showed that more peptide fractions with low molecular weight appeared in the hydrolysates of the HP‐treated PPI with increasing pressure. Moreover, the level of free SH of hydrolysates of the HP‐treated PPI was relatively higher than non‐HP‐treated PPI. The hydrolysates of the HP‐treated PPI exerted higher antioxidant activity (reducing power and DPPH radical scavenging) than the hydrolysates of non‐HP‐treated PPI. The results indicated that high pressure treatment affected the enzymatic hydrolysis of peanut protein and some protein structure properties and improved antioxidant activity of PPI hydrolysates.
Keywords	antioxidant activity ; enzymatic hydrolysis ; high pressure ; structure ; peanut protein
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article: [Skull base reconstruction strategies and techniques for endoscopic transnasal skull base surgery].

Jiang, Y

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

2023 Volume 58, Issue 5, Page(s) 419–424

MeSH term(s)	Humans ; Skull Base/surgery ; Endoscopy/methods ; Neurosurgical Procedures/methods
Language	Chinese
Publishing date	2023-04-24
Publishing country	China
Document type	Journal Article
ZDB-ID	2195655-8
ISSN	1673-0860
ISSN	1673-0860
DOI	10.3760/cma.j.cn115330-20220630-00401
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 3733: Show issues

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Article: Editorial: Multi-omics analysis of programmed cell death-mediated tumor microenvironment heterogeneity.

Jiang, Yanan

Frontiers in oncology

2024 Volume 14, Page(s) 1265418

Language	English
Publishing date	2024-03-26
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2024.1265418
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Article ; Online: Improving the diagnosis and treatment of congenital heart disease through the combination of three-dimensional echocardiography and image guided surgery.

Jiang, Yong

BMC medical imaging

2024 Volume 24, Issue 1, Page(s) 61

Abstract: Objective: The paper aimed to improve the accuracy limitations of traditional two-dimensional ultrasound and surgical procedures in the diagnosis and management of congenital heart disease (chd), and to improve the diagnostic and therapeutic level of ... ...

Abstract	Objective: The paper aimed to improve the accuracy limitations of traditional two-dimensional ultrasound and surgical procedures in the diagnosis and management of congenital heart disease (chd), and to improve the diagnostic and therapeutic level of chd. Method: This article first collected patient data through real-time imaging and body surface probes, and then diagnosed 150 patients using three-dimensional echocardiography. In order to verify the effectiveness of the combination therapy, 60 confirmed patients were divided into a control group and an experimental group. The control group received conventional two-dimensional ultrasound and surgical treatment, while the experimental group received three-dimensional ultrasound and image guided surgical treatment. Result: In the second diagnosis, the diagnostic accuracy of type 1, type 2, and type 3 in the control group was 84.21%, 84.02%, and 83.38%, respectively. The diagnostic accuracy rates of type 1, type 2, and type 3 in the experimental group were 92.73%, 92.82%, and 92.83%, respectively. In the control group, 2 males and 1 female experienced heart failure after surgery. However, in the experimental group, 0 males and 0 females experienced heart failure after surgery. Conclusion: The combination of three-dimensional echocardiography and image guided surgery can improve diagnostic accuracy and surgical treatment effectiveness, thereby reducing risks and complications, and improving surgical success rate.
MeSH term(s)	Male ; Humans ; Female ; Heart Defects, Congenital/diagnostic imaging ; Heart Defects, Congenital/surgery ; Echocardiography, Three-Dimensional/methods ; Ultrasonography ; Surgery, Computer-Assisted ; Heart Failure
Language	English
Publishing date	2024-03-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2061975-3
ISSN	1471-2342 ; 1471-2342
ISSN (online)	1471-2342
ISSN	1471-2342
DOI	10.1186/s12880-024-01235-2
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Article ; Online: Letter to the Editor Regarding "C-Reactive Protein/Albumin Ratio Is Associated with Mortality in Patients with Moderate to Severe Traumatic Brain Injury".

Jiang, Yan

World neurosurgery

2024 Volume 183, Page(s) 266

MeSH term(s)	Humans ; C-Reactive Protein ; Brain Injuries, Traumatic ; Brain Injuries ; Albumins
Chemical Substances	C-Reactive Protein (9007-41-4) ; Albumins
Language	English
Publishing date	2024-03-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2023.12.088
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Article: A theory of the neural mechanisms underlying negative cognitive bias in major depression.

Jiang, Yuyue

Frontiers in psychiatry

2024 Volume 15, Page(s) 1348474

Abstract: The widely acknowledged cognitive theory of depression, developed by Aaron Beck, focused on biased information processing that emphasizes the negative aspects of affective and conceptual information. Current attempts to discover the neurological ... ...

Abstract	The widely acknowledged cognitive theory of depression, developed by Aaron Beck, focused on biased information processing that emphasizes the negative aspects of affective and conceptual information. Current attempts to discover the neurological mechanism underlying such cognitive and affective bias have successfully identified various brain regions associated with severally biased functions such as emotion, attention, rumination, and inhibition control. However, the neurobiological mechanisms of how individuals in depression develop this selective processing toward negative is still under question. This paper introduces a neurological framework centered around the frontal-limbic circuit, specifically analyzing and synthesizing the activity and functional connectivity within the amygdala, hippocampus, and medial prefrontal cortex. Firstly, a possible explanation of how the positive feedback loop contributes to the persistent hyperactivity of the amygdala in depression at an automatic level is established. Building upon this, two hypotheses are presented: hypothesis 1 revolves around the bidirectional amygdalohippocampal projection facilitating the amplification of negative emotions and memories while concurrently contributing to the impediment of the retrieval of opposing information in the hippocampus attractor network. Hypothesis 2 highlights the involvement of the ventromedial prefrontal cortex in the establishment of a negative cognitive framework through the generalization of conceptual and emotional information in conjunction with the amygdala and hippocampus. The primary objective of this study is to improve and complement existing pathological models of depression, pushing the frontiers of current understanding in neuroscience of affective disorders, and eventually contributing to successful recovery from the debilitating affective disorders.
Language	English
Publishing date	2024-03-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2024.1348474
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Article ; Online: Osteoarthritis year in review 2021: biology.

Jiang, Y

Osteoarthritis and cartilage

2021 Volume 30, Issue 2, Page(s) 207–215

Abstract: This year in review on osteoarthritis biology summarizes a series of research articles published between the 2020 and 2021 Osteoarthritis Research Society International (OARSI) World Congress. Research hightlights were selected and discussed based on the ...

Abstract	This year in review on osteoarthritis biology summarizes a series of research articles published between the 2020 and 2021 Osteoarthritis Research Society International (OARSI) World Congress. Research hightlights were selected and discussed based on the new discoveries of OA's cellular molecular mechanism, anatomical signatures, potential therapeutic targets, and regenerative therapy. The recently developed potential therapeutic targets are summarized, and the research focuses on TGFβ and WNT signaling in joint tissue homeostasis, joint aging and the dynamic of synolytics in OA joint, and the roles of TRP2, LDHA, OSCAR in cartilage homeostasis and OA joints are highlighted. Subsquencially, new anatomical structures and OA features are introduced, such as synovitis-induced venous portal circulation, horiozontal fissures between cartilage and subchondral bone, the cellular derivation of osteophytes formation, OA subtypes, and subchondral remodeling and pain biology. Then, research on the possibility of tissue regeneration in OA joints are discussed; skeletal stem cells in OA cartilage regeneration, and preclinical results of regenerative therapy for meniscus tear and osteochondral tissue morphoghesis are included. At last, the clinical evidence of the importance of delivery site of bone marrow stem cells for OA treatment is discussed. These findings represent advances in our understanding of OA pathophysiology.
MeSH term(s)	Humans ; Osteoarthritis/diagnosis ; Osteoarthritis/etiology ; Osteoarthritis/therapy
Language	English
Publishing date	2021-11-18
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1167809-4
ISSN	1522-9653 ; 1063-4584
ISSN (online)	1522-9653
ISSN	1063-4584
DOI	10.1016/j.joca.2021.11.009
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Article ; Online: Surface defect detection of steel based on improved YOLOv5 algorithm.

Jiang, Yiwen

Mathematical biosciences and engineering : MBE

2023 Volume 20, Issue 11, Page(s) 19858–19870

Abstract: To address the challenge of achieving a balance between efficiency and performance in steel surface defect detection, this paper presents a novel algorithm that enhances the YOLOv5 defect detection model. The enhancement process begins by employing the K- ...

Abstract	To address the challenge of achieving a balance between efficiency and performance in steel surface defect detection, this paper presents a novel algorithm that enhances the YOLOv5 defect detection model. The enhancement process begins by employing the K-means++ algorithm to fine-tune the location of the prior anchor boxes, improving the matching process. Subsequently, the loss function is transitioned from generalized intersection over union (GIOU) to efficient intersection over union (EIOU) to mitigate the former's degeneration issues. To minimize information loss, Carafe upsampling replaces traditional upsampling techniques. Lastly, the squeeze and excitation networks (SE-Net) module is incorporated to augment the model's sensitivity to channel features. Experimental evaluations conducted on a public defect dataset reveal that the proposed method elevates the mean average precision (mAP) by seven percentage points compared to the original YOLOv5 model, achieving an mAP of 83.3%. Furthermore, our model's size is significantly reduced compared to other advanced algorithms, while maintaining a processing speed of 47 frames per second. This performance demonstrates the effectiveness of the proposed enhancements in improving both accuracy and efficiency in defect detection.
Language	English
Publishing date	2023-12-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2265126-3
ISSN	1551-0018 ; 1551-0018
ISSN (online)	1551-0018
ISSN	1551-0018
DOI	10.3934/mbe.2023879
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Article ; Online: White noise insole: an artificial evoked sensation device that can be expected to improve plantar sensation of diabetic foot.

Jiang, Yangzheng

Scientific reports

2023 Volume 13, Issue 1, Page(s) 20687

Abstract: Diabetic foot is a common severe complication of diabetes, and its main symptom is diabetic foot ulcer. The production of plantar diabetic foot ulcers is usually affected by two factors, namely neuropathy or vascular disease. While previous studies ... ...

Abstract	Diabetic foot is a common severe complication of diabetes, and its main symptom is diabetic foot ulcer. The production of plantar diabetic foot ulcers is usually affected by two factors, namely neuropathy or vascular disease. While previous studies proved that stochastic resonance (SR) could effectively enhance the plantar touch of patients with diabetic feet, the potential impact of SR on neural circuit feedback, especially on the input of the tactile nerves of the lower limbs, is less clear. This study aims to explore the potential impact on the tactile threshold of the human foot when using vibrating insoles. We study a white noise vibration insole based on SR mechanism. We compare and analyze the tactile threshold voltage (TTV) triggered by an electrical stimulation device in three main plantar pressure-bearing areas (the second metatarsal (M2), the fourth metatarsal (M4), and the heel (H) area) of 8 participants using EEG and self-developed vibration insole. Significance found in M2 and M4 areas, white noise signal (WNS) lowered the tactile threshold in these areas, and had a potentially positive impact on patients with diabetic feet, especially in the M4 area. The influence of WNS on the plantar heel area was still controversial. This study showed that WNS applied to the sole could improve the plantar tactile sensing ability of patients with diabetic feet, but it did not cover all areas. The application of WNS showed better benefits for the forefoot area than for the hindfoot area, which was speculated that may be related to the difference in the distribution density of blood vessels in plantar areas. Due to the impaired natural touch in participants with diabetic foot, using artificial evoked sensation WNS intervention, would be a feasible approach to improve plantar sensation.
MeSH term(s)	Humans ; Diabetic Foot/therapy ; Foot ; Sensation/physiology ; Heel ; Foot Orthoses ; Shoes ; Diabetes Mellitus
Language	English
Publishing date	2023-11-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-47263-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A game-theoretic approach to promoting waste management within the framework of a circular economy: implications for environmental protection.

Jiang, Yanyan

Environmental science and pollution research international

2023 Volume 31, Issue 5, Page(s) 6977–6991

Abstract: Currently, waste management classification is a critical topic that concerns not only environmental protection, but also the advancement of a circular economy. To address this issue within the context of a circular economy, this study develops an ... ...

Abstract	Currently, waste management classification is a critical topic that concerns not only environmental protection, but also the advancement of a circular economy. To address this issue within the context of a circular economy, this study develops an uncooperative triumvirate paradigm consisting of "central regulation, local promotion, and universal participation." The model analyzes the strategy choices of both the central and local governments while using an evolutionary game method to encourage residents to promote waste separation. Using numerical simulations, this study examines the variables that impact the strategy choices of the three parties over time. The results show that (1) the desire of the central government, local governments, and citizens to engage has varying effects on each of these entities; the conduct of local government is significantly influenced by the preparedness of the central government, but residents' behavior is comparatively less influenced by the central government's intention; in comparison, it is mainly affected by psychological expectations of income and expenditure; (2) the impact of the local government and residents on each other is characterized by an unbalanced relationship, with the local government being more sensitive to residents' willingness to participate and changes in policy support being more sensitive; and (3) residents show more sensitivity to incentive funds, compensation, penalties, and benefit distribution coefficients. To promote waste separation in China, it is crucial to establish a reasonable expectation of ecological civilization, establish an efficient mechanism for environmental protection supervision, refine local waste separation programs, increase local governments' responsibility for promoting them, ensure legal methods for universal participation, and improve the regulatory mechanism for universal participation to protect the environment. In addition, it is essential to improve the education system for waste separation and continue research related to waste separation.
MeSH term(s)	Conservation of Natural Resources ; Waste Management/methods ; Local Government ; China ; Health Expenditures ; Government
Language	English
Publishing date	2023-12-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-31532-2
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