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Article ; Online: Data Mining and Meta-Analysis of Psoriasis Based on Association Rules

Jiarui Ou / Jianglin Zhang

Journal of Healthcare Engineering, Vol

2022 Volume 2022

Abstract: Psoriasis is a common chronic and recurrent disease in dermatology, which has a great impact on the physical and mental health of patients. Meta-analysis can evaluate the effectiveness and safety of defubao in the treatment of psoriasis vulgaris. This ... ...

Abstract	Psoriasis is a common chronic and recurrent disease in dermatology, which has a great impact on the physical and mental health of patients. Meta-analysis can evaluate the effectiveness and safety of defubao in the treatment of psoriasis vulgaris. This article observes psoriasis skin lesions treated with topical defubao and the changes in blood vessels under dermoscopy. Considering that the Apriori algorithm and the existing improved algorithm have the problems of ignoring the weight and repeatedly scanning the database, this paper proposes a matrix association rule method based on random forest weighting. This method uses the random forest algorithm to assign weights to each item in the data set, and introduces matrix theory to convert the transaction data set into a matrix form and store it, thereby improving operating efficiency. This article included 11 studies, of which 7 studies used the indicator “Researcher’s Overall Assessment” (IGA) to evaluate the efficacy, 5 studies used the “Patient Overall Assessment” (PGA) as the efficacy evaluation index, and Loss Area and Severity Index (PASI) was used as an observation index to evaluate the efficacy. Seven studies conducted safety comparisons. In this paper, IGA and PGA were used as evaluation indicators. The treatment effect of the defubao group was better than the calcipotriol group and the betamethasone group. The differences were statistically significant. The effect of the Fubao treatment for 8 weeks is significantly better than that of 4 weeks and 2 weeks, and the differences are statistically different. Using PASI as the evaluation index, a descriptive study was carried out, and it was found that after 4 weeks of treatment for psoriasis vulgaris, the average PASI reduction rate of patients was higher than that of the calcipotriol group and the betamethasone group. The safety evaluation found that after 8 weeks of treatment, the incidence of adverse events in the defubao group was significantly lower than that in the calcipotriol group.
Keywords	Medicine (General) ; R5-920 ; Medical technology ; R855-855.5
Subject code	796
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Micronutrient deficiencies and cardiac health.

Rehman, Shazia / Jianglin, Zhang

Frontiers in nutrition

2022 Volume 9, Page(s) 1010737

Abstract: Inadequate diet and nutritional quality are potentially correlated with an escalated risk of cardiac-related morbidity and mortality. A plethora of knowledge is available regarding the influence of heart-healthy dietary patterns in response to disability- ...

Abstract	Inadequate diet and nutritional quality are potentially correlated with an escalated risk of cardiac-related morbidity and mortality. A plethora of knowledge is available regarding the influence of heart-healthy dietary patterns in response to disability-adjusted life years (DALYs), yet little is known regarding the best approaches to adopt. In response, the present investigation aims to bridge this knowledge gap by implementing mathematical machine learning grey methodology to assess the degree of influence and the potential contributing factors in DALYs due to ischemic heart disease and stroke, in conjunction with the Hurwicz (Min-Max) criterion. The outcomes highlighted that a diet low in fruits is a potential contributor to IHD-related DALYS, whereas a diet low in vegetables is a more grounded contributor to stroke-related DALYs in Spain, among others. Moreover, the Hurwicz approach highlighted IHD to be more impacted due to dietary and nutritional factors than stroke. In conclusion, our investigation strongly supports a balanced diet and precision nutrition guidelines as a strategy for reducing cardiac-related diseases in the Spanish population. It is a public health primary consideration to build an ambiance that encourages, rather than hinders, compliance with cardioprotective dietary practices among all people.
Language	English
Publishing date	2022-10-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2022.1010737
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Uptake of COVID-19 booster shot among healthcare workers: A mediation analysis approach.

Rehman, Shazia / Rehman, Erum / Jianglin, Zhang

Frontiers in public health

2022 Volume 10, Page(s) 1033473

Abstract: Since the thrust of previous research investigations has been on people's willingness to get immunized against the COVID-19 infection, the underpinning principle of compliance has received very little attention. Addressing the possible drivers and ... ...

Abstract	Since the thrust of previous research investigations has been on people's willingness to get immunized against the COVID-19 infection, the underpinning principle of compliance has received very little attention. Addressing the possible drivers and mechanisms influencing vaccine acceptance may provide significant insights for limiting the pandemic. In response, we intend to investigate the influence of decision regret and the consequences of post-vaccination adverse effects on the inclination to undertake booster shots. An electronic survey that was self-administered was conducted in Rawalpindi, Pakistan. The questionnaire was completed by 1,369 participants, with a response rate of 41%. 1,343 of them (98.10%) had received both doses of the COVID-19 vaccination. Besides, the present research has also adopted a mediation model. Our findings demonstrate that unfavorable vaccination responses in healthcare workers significantly affect their likelihood of receiving booster shots. Interestingly, healthcare workers who had adverse experiences after being immunized were more prone to regret their prior immunization decisions, which in response affected their decision to get a booster shot. The motivation to receive the booster dosage and adverse post-vaccination responses were mediated by decision regret. The outcomes suggested indissociable connections between unfavorable vaccination responses, decision regret, and the likelihood of receiving a booster shot. To strengthen immunization acceptance intent and enhance the likelihood of receiving COVID-19 booster shots, it is recommended that awareness of these post-vaccination adverse events be extensively integrated into immunization awareness programs and policy measures supporting booster doses.
MeSH term(s)	Humans ; COVID-19/prevention & control ; COVID-19 Vaccines ; Mediation Analysis ; Cross-Sectional Studies ; Health Personnel
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2022-10-05
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.1033473
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Article ; Online: Cardiovascular Disease Mortality and Potential Risk Factor in China: A Multi-Dimensional Assessment by a Grey Relational Approach.

Rehman, Shazia / Rehman, Erum / Mumtaz, Ayesha / Jianglin, Zhang

International journal of public health

2022 Volume 67, Page(s) 1604599

Abstract: Objectives: ...

Abstract	Objectives:
MeSH term(s)	Cardiovascular Diseases ; China/epidemiology ; Cholesterol ; Coronary Disease ; Humans ; Hypertension/complications ; Prospective Studies ; Pulmonary Heart Disease/complications ; Risk Factors ; Stroke
Chemical Substances	Cholesterol (97C5T2UQ7J)
Language	English
Publishing date	2022-04-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2274130-6
ISSN	1661-8564 ; 1661-8556
ISSN (online)	1661-8564
ISSN	1661-8556
DOI	10.3389/ijph.2022.1604599
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Article ; Online: Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity

Fanghui Ma / Qing Zhou / Minghui Yang / Jianglin Zhang / Xiang Chen

Nanomaterials, Vol 12, Iss 16, p

2022 Volume 2787

Abstract: Sulfur quantum dots (SQDs) are a kind of pure elemental quantum dots, which are considered as potential green nanomaterials because they do not contain heavy metal elements and are friendly to biology and environment. In this paper, SQDs with size around ...

Abstract	Sulfur quantum dots (SQDs) are a kind of pure elemental quantum dots, which are considered as potential green nanomaterials because they do not contain heavy metal elements and are friendly to biology and environment. In this paper, SQDs with size around 2 nm were synthesized by a microwave-assisted method using sulfur powder as precursor. The SQDs had the highest emission under the excitation of 380 nm and emit blue fluorescence at 470 nm. In addition, the SQDs had good water solubility and stability. Based on the synthesized SQDs, a fluorescence assay for detection of alkaline phosphatase (ALP) was reported. The fluorescence of the SQDs was initially quenched by Cr (VI). In the presence of ALP, ALP-catalyzed hydrolysis of 2-phospho-L-ascorbic acid to generate ascorbic acid. The generated ascorbic acid can reduce Cr (VI) to Cr (III), thus the fluorescence intensity of SQDs was restored. The assay has good sensitivity and selectivity and was applied to the detection of ALP in serum samples. The interesting properties of SQDs can find a wide range of applications in different sensing and imaging areas.
Keywords	sulfur quantum dots ; nanomaterials ; fluorescence sensing ; alkaline phosphatase ; ascorbic acid ; Chemistry ; QD1-999
Subject code	540 ; 500
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Approaching expert-level accuracy for differentiating ACL tear types on MRI with deep learning

Yang Xue / Shu Yang / Wenjie Sun / Hui Tan / Kaibin Lin / Li Peng / Zheng Wang / Jianglin Zhang

Scientific Reports, Vol 14, Iss 1, Pp 1-

2024 Volume 11

Abstract: Abstract Treatment for anterior cruciate ligament (ACL) tears depends on the condition of the ligament. We aimed to identify different tear statuses from preoperative MRI using deep learning-based radiomics with sex and age. We reviewed 862 patients with ...

Abstract	Abstract Treatment for anterior cruciate ligament (ACL) tears depends on the condition of the ligament. We aimed to identify different tear statuses from preoperative MRI using deep learning-based radiomics with sex and age. We reviewed 862 patients with preoperative MRI scans reflecting ACL status from Hunan Provincial People’s Hospital. Based on sagittal proton density-weighted images, a fully automated approach was developed that consisted of a deep learning model for segmenting ACL tissue (ACL-DNet) and a deep learning-based recognizer for ligament status classification (ACL-SNet). The efficacy of the proposed approach was evaluated by using the sensitivity, specificity and area under the receiver operating characteristic curve (AUC) and compared with that of a group of three orthopedists in the holdout test set. The ACL-DNet model yielded a Dice coefficient of 98% ± 6% on the MRI datasets. Our proposed classification model yielded a sensitivity of 97% and a specificity of 97%. In comparison, the sensitivity of alternative models ranged from 84 to 90%, while the specificity was between 86 and 92%. The AUC of the ACL-SNet model was 99%, demonstrating high overall diagnostic accuracy. The diagnostic performance of the clinical experts as reflected in the AUC was 96%, 92% and 88%, respectively. The fully automated model shows potential as a highly reliable and reproducible tool that allows orthopedists to noninvasively identify the ACL status and may aid in optimizing different techniques, such as ACL remnant preservation, for ACL reconstruction.
Keywords	Medicine ; R ; Science ; Q
Subject code	610
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Correction to: Cardiovascular disease (CVD): assessment, prediction and policy implications.

Rehman, Shazia / Rehman, Erum / Ikram, Muhammad / Jianglin, Zhang

BMC public health

2021 Volume 21, Issue 1, Page(s) 1382

Language	English
Publishing date	2021-07-12
Publishing country	England
Document type	Published Erratum
ISSN	1471-2458
ISSN (online)	1471-2458
DOI	10.1186/s12889-021-11450-z
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Article ; Online: Socioeconomic Influence on Cardiac Mortality in the South Asian Region: New Perspectives from Grey Modeling and G-TOPSIS.

Rehman, Shazia / Rehman, Erum / Hussain, Iftikhar / Jianglin, Zhang

Journal of healthcare engineering

2021 Volume 2021, Page(s) 6866246

Abstract: Background: Measuring the potential socioeconomic factors of cardiac mortality is fundamental to identifying treatments, setting priorities, and effectively allocating resources to minimize disease burden. The study sought to present a methodology that ... ...

Abstract	Background: Measuring the potential socioeconomic factors of cardiac mortality is fundamental to identifying treatments, setting priorities, and effectively allocating resources to minimize disease burden. The study sought to present a methodology that explores the connections between urbanization, population growth, human development index (HDI), access to energy, unemployment, and cardiovascular disease (CVD) mortality within the South Asian Association for Regional Cooperation (SAARC) nations to mitigate the cardiac disease burden. Methods: This investigation uses multiple-criteria decision-making methodologies to analyze data between 2001 and 2017 commencing with a mathematical grey incidence analysis (GIA) methodology to estimate weights and rank nations based on CVD mortality. Then, utilizing the conservative min-max model approach, we sought to determine which country contributes the most to CVD mortality among all South Asian nations. The grey preference by similarity to ideal solution (G-TOPSIS) method is adopted for further optimization by prioritizing the selected factors that have the greatest influence on CVD mortality. Results: The estimated statistic highlights that, among SAARC nations, Pakistan has a significant proportion of the disease burden attributable to cardiac events. In addition, HDI showed a significant contribution in the reduction of CVD mortality, whereas unemployment showed a significant contribution in the rise of CVD mortality among all selected variables. Conclusions: This investigation may facilitate researchers with a multiple-criteria decision-making roadmap to help them enhance the quality of their studies and their understanding of how to use multiple-criteria decision-making techniques to evaluate and prioritize the influencing factors of disease mortality in healthcare research. Further, the study outcomes provide additional practical knowledge for appropriate policy solutions.
MeSH term(s)	Cardiovascular Diseases/epidemiology ; Humans ; Incidence ; Pakistan ; Socioeconomic Factors
Language	English
Publishing date	2021-11-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2545054-2
ISSN	2040-2309 ; 2040-2295
ISSN (online)	2040-2309
ISSN	2040-2295
DOI	10.1155/2021/6866246
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Article ; Online: Cardiovascular disease (CVD): assessment, prediction and policy implications.

Rehman, Shazia / Rehman, Erum / Ikram, Muhammad / Jianglin, Zhang

BMC public health

2021 Volume 21, Issue 1, Page(s) 1299

Abstract: Background: The study aims to predict and assess cardiovascular disease (CVD) patterns in highly affected countries such as Pakistan, India, China, Kenya, the USA, and Sweden. The data for CVD deaths was gathered from 2005 to 2019.: Methods: We ... ...

Abstract	Background: The study aims to predict and assess cardiovascular disease (CVD) patterns in highly affected countries such as Pakistan, India, China, Kenya, the USA, and Sweden. The data for CVD deaths was gathered from 2005 to 2019. Methods: We utilized non-homogenous discrete grey model (NDGM) to predict growth of cardiovascular deaths in selected countries. We take this process a step further by utilizing novel Synthetic Relative Growth Rate (RGR) and Synthetic Doubling Time (Dt) model to assess how many years it takes to reduce the cardiovascular deaths double in numbers. Results: The results reveal that the USA and China may lead in terms of raising its number of deaths caused by CVDs till 2027. However, doubling time model suggests that USA may require 2.3 years in reducing the cardiovascular deaths. Conclusions: This study is significant for the policymakers and health practitioners to ensure the execution of CVD prevention measures to overcome the growing burden of CVD deaths.
MeSH term(s)	Cardiovascular Diseases ; China/epidemiology ; Humans ; India ; Kenya ; Pakistan ; Policy ; Risk Factors ; Sweden
Language	English
Publishing date	2021-07-02
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-021-11334-2
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Article ; Online: Long-Term Chemical Fertilization Drove Beneficial Bacteria for Rice Soil to Move from Bulk Soil to the Rhizosphere

Jian Xiao / Jianglin Zhang / Yajie Gao / Yanhong Lu / Xue Xie / Changyu Fang / Yulin Liao / Jun Nie

Agronomy, Vol 13, Iss 1645, p

2023 Volume 1645

Abstract: Overuse of chemical fertilizer (CF) causes damage to soil and the environment. To reveal the process of the response of crop rhizospheric and bulk soil fertility and the bacterial community to long-term CF conditions, CF application and nonfertilization ( ...

Abstract	Overuse of chemical fertilizer (CF) causes damage to soil and the environment. To reveal the process of the response of crop rhizospheric and bulk soil fertility and the bacterial community to long-term CF conditions, CF application and nonfertilization (CK, control) treatments were used in a long-term (12-year) fertilization experiment. Long-term CF application significantly increased the soil organic matter, total nitrogen, and available phosphorus contents ( p < 0.05), increased the available nitrogen (AN) and potassium (AK) contents to varying degrees, and decreased the soil pH in both rice rhizospheric soil and bulk soil. In addition, the bacterial Shannon and Ace indices in rice rhizospheric soil under the CF treatment were all higher than those under the control (CK) treatment, and the bulk soil bacteria showed the opposite trend. The LEfSe results showed that unidentified_Gammaproteobacteria and Geobacter (genera) were significantly enriched in the rhizospheric and bulk soil of rice under the CK treatment, respectively. Gemmatimonadetes (phylum) and Nitrospirae (phylum) + Thiobacillus (genus) were significantly enriched in the rice rhizospheric and bulk soil under the CF treatment. Only AK and AN had strong positive correlations with soil bacteria. Long-term CF application accelerated the migration of soil bacteria from the bulk soil to the rhizosphere, thus improving soil fertility and nutrient cycling.
Keywords	paddy soil ; fertilization ; rhizosphere ; bulk soil ; bacterial community ; Agriculture ; S
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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