LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 38

Search options

  1. Article ; Online: Exome-Based Amino Acid Optimization: A Dietary Strategy to Satisfy Human Nutritional Demands and Enhance Muscle Strength in Breast Tumor Mice Undergoing Chemotherapy.

    Gong, Congcong / Jiao, Chunwei / Liang, Huijia / Ma, Yuxin / Wu, Qingping / Xie, Yizhen

    Journal of agricultural and food chemistry

    2024  Volume 72, Issue 13, Page(s) 7089–7099

    Abstract: Breast cancer patients undergoing chemotherapy often experience muscle wasting and weakness, which impact their quality of life. A potential solution lies in customizing amino acid compositions based on exome-derived formulations (ExAAs). The study ... ...

    Abstract Breast cancer patients undergoing chemotherapy often experience muscle wasting and weakness, which impact their quality of life. A potential solution lies in customizing amino acid compositions based on exome-derived formulations (ExAAs). The study hypothesized that tailoring dietary amino acids using ExAAs could enhance muscle health. Theoretical amino acid requirements were calculated from the genome's exome region, and a breast cancer mouse model undergoing paclitaxel treatment was established. The mice were supplemented with a cancer-specific nutritional formula (QJS), and the effects of QJS and amino acid-adjusted QJS (adjQJS) were compared. Both formulations improved the nutritional status without compromising tumor growth. Notably, adjQJS significantly enhanced muscle strength compared to QJS (1.51 ± 0.25
    MeSH term(s) Humans ; Animals ; Mice ; Female ; Exome/genetics ; Quality of Life ; Amino Acids/metabolism ; Diet ; Muscle Strength ; Muscle, Skeletal/metabolism ; Dietary Supplements ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism
    Chemical Substances Amino Acids
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c07256
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Transcriptomic analysis of the anti-inflammatory effect of

    Jiao, Chunwei / Liang, Huijia / Liu, Li / Li, Shunxian / Chen, Jiaming / Xie, Yizhen

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 1035101

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-10-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.1035101
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Identification of Long Non-Coding RNAs and Their Target Genes from Mycelium and Primordium in Model Mushroom

    Wu, Tuheng / Chen, Jian / Jiao, Chunwei / Hu, Huiping / Wu, Qingping / Xie, Yizhen

    Mycobiology

    2022  Volume 50, Issue 5, Page(s) 357–365

    Abstract: Schizophyllum ... ...

    Abstract Schizophyllum commune
    Language English
    Publishing date 2022-10-25
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2631580-4
    ISSN 2092-9323 ; 1229-8093
    ISSN (online) 2092-9323
    ISSN 1229-8093
    DOI 10.1080/12298093.2022.2116819
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Grifola frondosa GF5000 improves insulin resistance by modulation the composition of gut microbiota in diabetic rats

    Xiao, Chun / Jiao, Chunwei / Xie, Yizhen / Ye, Linhui / Li, Qianqing / Wu, Qingping

    Journal of functional foods. 2021 Feb., v. 77

    2021  

    Abstract: The aim was to investigate whether Grifola frondosa fraction (Mw > 5000D) (GF5000) could restore the gut microbiota dysbiosis to improves insulin resistance in diabetic rats. Oral glucose tolerance test and serum biochemical parameter were assessed of ... ...

    Abstract The aim was to investigate whether Grifola frondosa fraction (Mw > 5000D) (GF5000) could restore the gut microbiota dysbiosis to improves insulin resistance in diabetic rats. Oral glucose tolerance test and serum biochemical parameter were assessed of the hypoglycemic activity of GF5000 (112.5 and 675 mg/kg/d, i.g.) in diabetic rats for 48 d. The mRNA and protein levels of inflammatory markers in epididymal white adipose tissue were determined by qPCR and western blotting. In rats intestinal tissue, sequencing of the V3-4 region of 16S rRNA genes were analyzed. GF5000 significantly lowered fasting serum glucose (P < 0.05), the area under the curve (P < 0.01), insulin resistance index (P < 0.01) and serum lipids profile (P < 0.05) in diabetic rats. GF5000 decreased the mRNA levels of inflammatory markers (P < 0.05), simultaneously modulated the composition of gut microbiota. Data suggests that the potential of GF5000 improvement insulin resistant is relation of alleviation the inflammation by modulating composition of gut microbiota.
    Keywords Grifola frondosa ; Western blotting ; area ; blood glucose ; blood lipids ; dysbiosis ; epididymis ; functional foods ; genes ; glucose tolerance tests ; glycemic effect ; inflammation ; insulin resistance ; intestinal microorganisms ; intestines ; protein content ; rats ; white adipose tissue
    Language English
    Dates of publication 2021-02
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-light
    ZDB-ID 2511964-3
    ISSN 1756-4646
    ISSN 1756-4646
    DOI 10.1016/j.jff.2020.104313
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 7830: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: An active ingredient isolated from

    Jiao, Chunwei / Yun, Hao / Liang, Huijia / Lian, Xiaodong / Li, Shunxian / Chen, Jiaming / Qadir, Javeria / Yang, Burton B / Xie, Yizhen

    Aging

    2022  Volume 14, Issue 13, Page(s) 5376–5389

    Abstract: ... The ... ...

    Abstract The mushroom
    MeSH term(s) Animals ; Burns/drug therapy ; Cell Proliferation ; Mice ; Oils/pharmacology ; Reishi ; Smad Proteins ; TRPV Cation Channels/pharmacology ; Wound Healing
    Chemical Substances Oils ; Smad Proteins ; TRPV Cation Channels ; TRPV1 protein, mouse
    Language English
    Publishing date 2022-06-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.204119
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Novel Selenium Peptides Obtained from Selenium-Enriched Cordyceps militaris Alleviate Neuroinflammation and Gut Microbiota Dysbacteriosis in LPS-Injured Mice

    Wu, Shujian / Wu, Qingping / Wang, Juan / Li, Yangfu / Chen, Bo / Zhu, Zhenjun / Huang, Rui / Chen, Mengfei / Huang, Aohuan / Xie, Yizhen / Jiao, Chunwei / Ding, Yu

    Journal of agricultural and food chemistry. 2022 Mar. 03, v. 70, no. 10

    2022  

    Abstract: Increasing attention focuses on the relationship between neuroinflammation and Alzheimer’s disease (AD). The reports on the microbiota–gut–brain axis reveal that the regulation by gut microbiota is an effective way to intervene in neuroinflammation- ... ...

    Abstract Increasing attention focuses on the relationship between neuroinflammation and Alzheimer’s disease (AD). The reports on the microbiota–gut–brain axis reveal that the regulation by gut microbiota is an effective way to intervene in neuroinflammation-related AD. In this study, two novel selenium peptides (Se-Ps), VPRKL(Se)M (Se-P1) and RYNA(Se)MNDYT (Se-P2), with neuroprotection effects were obtained from Se-enriched Cordyceps militaris. Se-P1 and Se-P2 pre-protection led to a 30 and 33% increase in the PC-12 cell viability compared to the damage group, respectively. Moreover, Se-Ps exhibited a significant pre-protection against LPS-induced inflammatory and oxidative stress in the colon and brain by inhibiting the production of pro-inflammatory mediators (p < 0.05) and malondialdehyde, as well as promoting anti-inflammatory cytokine level and antioxidant enzyme activity (p < 0.05), which may alleviate the cognitive impairment in LPS-injured mice (p < 0.05). Se-Ps not only repaired the intestinal mucosa damage of LPS-injured mice but also had a positive effect on gut microbiota dysbacteriosis by increasing the abundance of Lactobacillus and Alistipes and decreasing the abundance of Akkermansia and Bacteroides. Collectively, the antioxidant, anti-inflammatory, and regulating properties on gut microflora of Se-Ps contribute to their neuroprotection, supporting that Se-Ps could be a promising dietary supplement in the prevention and/or treatment of AD.
    Keywords Bacteroides ; Cordyceps militaris ; Lactobacillus ; antioxidant enzymes ; brain ; cell viability ; cognitive disorders ; colon ; cytokines ; dietary supplements ; dysbiosis ; enzyme activity ; food chemistry ; intestinal microorganisms ; intestinal mucosa ; malondialdehyde ; neuroprotective effect ; oxidative stress ; selenium
    Language English
    Dates of publication 2022-0303
    Size p. 3194-3206.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.1c08393
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 1185: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article: Whole Agrocybe cylindracea Prevented Obesity Linking with Modification of Gut Microbiota and Associated Fecal Metabolites in High‐Fat Diet‐Fed Mice

    Zhu, Zhenjun / Huang, Rui / Liu, Wei / Wang, Juan / Wu, Shujian / Chen, Mengfei / Huang, Aohuan / Xie, Yizhen / Chen, Moutong / Jiao, Chunwei / Zhang, Jumei / Wu, Qingping / Ding, Yu

    Molecular nutrition & food research. 2022 Apr., v. 66, no. 7

    2022  

    Abstract: SCOPE: Whole‐food‐based strategies to prevent metabolic diseases are growing interests. Agrocybe cylindracea (AC) is a major edible mushroom with high values of nutrition, but little is known about its health benefits as a portion of whole food. METHODS ... ...

    Abstract SCOPE: Whole‐food‐based strategies to prevent metabolic diseases are growing interests. Agrocybe cylindracea (AC) is a major edible mushroom with high values of nutrition, but little is known about its health benefits as a portion of whole food. METHODS AND RESULTS: Diet‐induced obese, C57BL/6J mice are fed an high‐fat diet (HFD) with or without AC (3% or 5%, w/w in the diet) for 9 weeks. The results show that dietary AC reduced body weight, adipose accumulation, impairment of glucose tolerance, lipid levels, and liver injury in HFD‐fed mice. Moreover, AC not only prevents HFD‐induced gut disorder, as indicates by the enriched probiotic Bifidobacterium and reduced endotoxin‐bearing Proteobacteria, but also improve the lipopolysaccharide (LPS) level and gut tissue structure. Fecal metabolites such as harmine and harmanine are also remarkably altered by AC. Spearman's correlation analysis reveals that the AC‐altered microbes and metabolites are strongly correlated with obesity‐related indexes. CONCLUSION: These findings suggest that dietary AC prevents HFD‐induced obesity and its complications in association with modulating gut microbiota and associated fecal metabolites.
    Keywords Agrocybe ; Bifidobacterium ; Proteobacteria ; food research ; glucose tolerance ; high fat diet ; intestinal microorganisms ; lipopolysaccharides ; liver ; metabolites ; mushrooms ; obesity ; probiotics
    Language English
    Dates of publication 2022-04
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202100897
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Polysaccharide from Agrocybe cylindracea prevents diet-induced obesity through inhibiting inflammation mediated by gut microbiota and associated metabolites

    Zhu, Zhenjun / Huang, Rui / Huang, Aohuan / Wang, Juan / Liu, Wei / Wu, Shujian / Chen, Mengfei / Chen, Moutong / Xie, Yizhen / Jiao, Chunwei / Zhang, Jumei / Wu, Qingping / Ding, Yu

    International Journal of Biological Macromolecules. 2022 June, v. 209 p.1430-1438

    2022  

    Abstract: Polysaccharide from Agrocybe cylindracea (ACP) has been demonstrated with various health benefits, but its anti-obesity effect and underlying mechanisms remain poorly understood. This study aimed to investigate the beneficial effects of ACP in high-fat ... ...

    Abstract Polysaccharide from Agrocybe cylindracea (ACP) has been demonstrated with various health benefits, but its anti-obesity effect and underlying mechanisms remain poorly understood. This study aimed to investigate the beneficial effects of ACP in high-fat diet (HFD)-induced obese mice by targeting gut microbiota and metabolites. 9-week ACP supplementation in HFD-fed mice reduced body weight, adipose accumulation, impaired insulin resistance, lipid levels, and liver injuries, which were negatively correlated to the pro-inflammatory factors, particularly tumor necrosis factor-alpha (TNF-α) and interleukin- 6 (IL-6). Moreover, ACP not only restored HFD-induced gut disorder, as indicated by the depletion of Desulfovibrio and Oscillibacter and the enrichment of the Bacteroides, Parabacteroides, Butyricimonas, and Dubosiella, but also positively regulated gut metabolites such as solavetivone and N-acetylneuraminic acid. Spearman's correlation analysis revealed that the ACP-altered microbes and metabolites were highly correlated with inflammation-related indexes. Notably, ACP greatly lowered the obesity-related TNF-α- and IL-6-levels partially by reducing Desulfovibrio and increasing Parabacteroides abundances, together with the associated decrease of solavetivone level. These findings suggest that ACP may be used as a prebiotic agent to prevent diet-induced obesity, and target-specific microbiota and metabolites may have unique therapeutic promise for inflammation-related diseases.
    Keywords Agrocybe ; Bacteroides ; Desulfovibrio ; anti-obesity effects ; high fat diet ; inflammation ; insulin resistance ; interleukin-6 ; intestinal microorganisms ; lipids ; liver ; metabolites ; obesity ; polysaccharides ; prebiotics ; sialic acid ; therapeutics ; tumor necrosis factor-alpha ; Agrocybe cylindracea ; Polysaccharide ; High-fat diet ; Gut microbiota
    Language English
    Dates of publication 2022-06
    Size p. 1430-1438.
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2022.04.107
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2374: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Whole-Genome Sequencing and Transcriptome Analysis of

    Wu, Tuheng / Cai, Manjun / Hu, Huiping / Jiao, Chunwei / Zhang, Zhi / Liu, Yuanchao / Chen, Jian / Xiao, Chun / Li, Xiangmin / Gao, Xiong / Chen, Shaodan / Wu, Qingping / Xie, Yizhen

    Journal of fungi (Basel, Switzerland)

    2022  Volume 8, Issue 10

    Abstract: Ganoderma ... ...

    Abstract Ganoderma lucidum
    Language English
    Publishing date 2022-10-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8101081
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Novel Selenium Peptides Obtained from Selenium-Enriched

    Wu, Shujian / Wu, Qingping / Wang, Juan / Li, Yangfu / Chen, Bo / Zhu, Zhenjun / Huang, Rui / Chen, Mengfei / Huang, Aohuan / Xie, Yizhen / Jiao, Chunwei / Ding, Yu

    Journal of agricultural and food chemistry

    2022  Volume 70, Issue 10, Page(s) 3194–3206

    Abstract: Increasing attention focuses on the relationship between neuroinflammation and Alzheimer's disease (AD). The reports on the microbiota-gut-brain axis reveal that the regulation by gut microbiota is an effective way to intervene in neuroinflammation- ... ...

    Abstract Increasing attention focuses on the relationship between neuroinflammation and Alzheimer's disease (AD). The reports on the microbiota-gut-brain axis reveal that the regulation by gut microbiota is an effective way to intervene in neuroinflammation-related AD. In this study, two novel selenium peptides (Se-Ps), VPRKL(
    MeSH term(s) Animals ; Cordyceps/chemistry ; Dysbiosis/drug therapy ; Gastrointestinal Microbiome ; Lipopolysaccharides/adverse effects ; Mice ; Neuroinflammatory Diseases ; Peptides/pharmacology ; Selenium/chemistry
    Chemical Substances Lipopolysaccharides ; Peptides ; Selenium (H6241UJ22B)
    Language English
    Publishing date 2022-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.1c08393
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top