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Article ; Online: UroVysion™ fluorescence in situ hybridization (FISH) possibly has a high positive rate in carcinoma of non-urothelial lineages

Chunjin Ke / Xuguang Liu / Jie Wan / Zhiquan Hu / Chunguang Yang

Frontiers in Molecular Biosciences, Vol

2023 Volume 10

Abstract: Background: Positive UroVysion™ fluorescence in situ hybridization (FISH) is generally considered as urothelial carcinoma (UC). We clarify if UroVysion™ FISH can be positive in carcinoma of non-urothelial lineages (CNUL), and verify the consistency of ... ...

Abstract	Background: Positive UroVysion™ fluorescence in situ hybridization (FISH) is generally considered as urothelial carcinoma (UC). We clarify if UroVysion™ FISH can be positive in carcinoma of non-urothelial lineages (CNUL), and verify the consistency of urine FISH and histological FISH in CNUL.Methods: All CNUL subjects detected by urine FISH assay due to haematuria from Tongji Hospital were screened. Meanwhile, 2 glandular cystitis and 2 urothelial carcinoma were served as negative or positive control. Paraffin-embedded tissue sections of all subjects were sent to the pathology department for histological FISH detection.Results: A total of 27 patients were included in this study, including 9 with adenocarcinomas, 11 with squamous cell carcinomas, and 7 with other tumour types. The overall positive rate in urine FISH was 64.00% (16/25) in patients with CNUL, 77.78% (7/9) in those with adenocarcinoma and 54.55% (6/11) in those with squamous carcinoma. There was a significant difference in the GLP p16 gene deletion rate between UC and CNUL (100% vs. 8.00%, p = 0.017). Histological FISH results showed that the histological results of 19 patients were consistent with their urine FISH results, and only one patient with stage Ⅲa urachal carcinoma had inconsistent histological FISH results (positive) and urine FISH (negative) results.Conclusion: We demonstrated for the first time the application value of FISH in CNUL on urine samples. Positive urine FISH tests indicate not only UC, but also CNUL. UroVysion™ FISH possibly has a high positive rate in CNUL. CNUL and UC have different genetic changes shown by FISH.
Keywords	fluorescence in situ hybridization ; chromosome ; CNUL ; squamous cell carcinoma ; adenocarcinoma ; Biology (General) ; QH301-705.5
Subject code	616
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Shannon Entropy in LS-Coupled Configuration Space for Ni-like Isoelectronic Sequence

Jian-Jie Wan / Jie Gu / Jiao Li / Na Guo

Entropy, Vol 24, Iss 267, p

2022 Volume 267

Abstract: The Shannon entropy in an LS-coupled configuration space has been calculated through a transformation from that in a jj-coupled configuration space for a Ni-like isoelectronic sequence. The sudden change of Shannon entropy, information exchange, ... ...

Abstract	The Shannon entropy in an LS-coupled configuration space has been calculated through a transformation from that in a jj-coupled configuration space for a Ni-like isoelectronic sequence. The sudden change of Shannon entropy, information exchange, eigenlevel anticrossing, and strong configuration interaction have been presented for adjacent levels. It is shown that eigenlevel anticrossing is a sufficient and necessary condition for the sudden change of Shannon entropy, and both of them are a sufficient condition for information exchange, which is the same as the case of the jj-coupled configuration space. It is found that the structure of sudden change from jj-coupled into LS-coupled configuration spaces through the LS-jj transformation is invariant for Shannon entropy along the isoelectronic sequence. What is more, in an LS-coupled configuration space, there are a large number of information exchanges between energy levels whether with or without strong configuration interaction, and most of the ground and single excited states of Ni-like ions are more suitable to be described by a jj-coupled or other configuration basis set instead of an LS-coupled configuration basis set according to the configuration mixing coefficients and their Shannon entropy. In this sense, Shannon entropy can also be used to measure the applicability of a configuration basis set or the purity of atomic state functions in different coupling schemes.
Keywords	Shannon entropy ; LS-coupled configuration space ; LS-jj transformation ; unique notation ; Science ; Q ; Astrophysics ; QB460-466 ; Physics ; QC1-999
Subject code	539
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of Chinese Carbon Emissions Trading Policy on Chongqing’s Carbon Emissions and Economic Development

Xiaoyu Ju / Jie Wan / Ziwei Zhang / Chunai Ma / Liangwei Zhang / Xiaodong Zhao

Sustainability, Vol 15, Iss 4253, p

2023 Volume 4253

Abstract: Balancing sustainable economic growth and environmental protection in developing countries is an important way to mitigate climate change. Based on panel data from nine provinces along the Silk Road Economic Belt between 2004 and 2021, this paper takes ... ...

Abstract	Balancing sustainable economic growth and environmental protection in developing countries is an important way to mitigate climate change. Based on panel data from nine provinces along the Silk Road Economic Belt between 2004 and 2021, this paper takes Chongqing, a pilot city for carbon trading rights, as the experimental group and the remaining eight provinces as the control group; we mainly analyze the impact of the carbon emissions trading policy on Chongqing’s carbon emissions and economic development after its implementation in 2013 using the difference-in-differences method (DID) and propensity score matching difference-in-differences method (PSM-DID). Then we use the synthetic control method (SCM) to test its robustness. The results showed that while maintaining the economic development speed, carbon trading helps to reduce carbon emissions. In addition, we also found that the economic activity effect and the energy intensity effect are the mediating effects of the carbon emissions reduction. Finally, taking the policy effect of the carbon emissions trading in Chongqing as a reference, this article confirmed the importance of aligning the carbon trading pathway with targeted green policies from the government. The government should drive the establishment of a regional carbon market in the nine provinces along the Silk Road Economic Belt, which could help to achieve sustainable development.
Keywords	sustainable development ; carbon neutral ; carbon trading ; carbon emissions ; economic development ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	381
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: NeiEA-NET

Yongyang Xu / Wei Tang / Ziyin Zeng / Weichao Wu / Jie Wan / Han Guo / Zhong Xie

International Journal of Applied Earth Observations and Geoinformation, Vol 119, Iss , Pp 103285- (2023)

Semantic segmentation of large-scale point cloud scene via neighbor enhancement and aggregation

2023

Abstract: 3D point cloud semantic segmentation is crucial for 3D environment perception and scene understanding, where learning of local context in point clouds is a crucial challenge. Existing approaches typically explore local context based on the predefined ... ...

Abstract	3D point cloud semantic segmentation is crucial for 3D environment perception and scene understanding, where learning of local context in point clouds is a crucial challenge. Existing approaches typically explore local context based on the predefined neighbors of point clouds. However, the widely used K-nearest neighbor algorithm (KNN) is far from optimal in defining local neighbors. In this study, we propose NeiEA-Net, a conceptually simple and effective network for point cloud semantic segmentation. The key to our approach is to optimize the local neighbors in 3D Euclidean space by taking full advantage of high-dimensional feature space as much as possible. In addition, we introduce a neighbor feature aggregation module to adaptively aggregate features with different scales in the local neighbors to further reduce the redundant information, thereby effectively learning the local details of point clouds. Experiments conducted on three large-scale benchmarks, S3DIS, Toronto3D and SensatUrban, demonstrate the superiority of our network.
Keywords	Point cloud ; 3D semantic segmentation ; Large-scale scene ; KNN ; Physical geography ; GB3-5030 ; Environmental sciences ; GE1-350
Subject code	006 ; 004
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A new species of Diglyphus Walker (Hymenoptera, Eulophidae) from China, with morphological characterizations and molecular analysis

Wei-Jie Wan / Su-Jie Du / Christer Hansson / Wan-Xue Liu

ZooKeys, Vol 1148, Iss , Pp 65-

2023 Volume 78

Abstract: Diglyphus Walker, 1844 (Hymenoptera: Eulophidae) is an economically important genus including species acting as biocontrol agents against agromyzid leafminer pests. A new species of Diglyphus, Diglyphus difasciatus Liu, Hansson & Wan, sp. nov., was ... ...

Abstract	Diglyphus Walker, 1844 (Hymenoptera: Eulophidae) is an economically important genus including species acting as biocontrol agents against agromyzid leafminer pests. A new species of Diglyphus, Diglyphus difasciatus Liu, Hansson & Wan, sp. nov., was discovered during the identification of agromyzid leafminers and their associated parasitoid wasps collected from 2016 to 2022 in China, based on morphological characteristics and molecular analyses of COI, ITS2 and 28S genes. Diglyphus difasciatus is similar to D. bimaculatus Zhu, LaSalle & Huang, distinguished by two interconnected infuscate vertical bands on the fore wing and the color of the scape. Molecular data support D. difasciatus and D. bimaculatus as two different species. The mean genetic distances between D. difasciatus and D. bimaculatus were 11.33%, 8.62%, and 0.18%, based on the COI, ITS2, and 28S genes, respectively.
Keywords	Zoology ; QL1-991
Subject code	590
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Pensoft Publishers
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A direct prediction method for wind power ramp events considering the class imbalanced problem

Guorui Ren / Jie Wan / Yanjia Wang / Kun Yao / Junfeng Fu / Jilai Yu

Energy Science & Engineering, Vol 11, Iss 5, Pp 1705-

2023 Volume 1715

Abstract: Abstract Predicting wind power ramp events directly based on the historical ramp event time series has drawn increasing attention recently. But the class imbalance problem of the ramp event time series significantly affects the prediction accuracy of ... ...

Abstract	Abstract Predicting wind power ramp events directly based on the historical ramp event time series has drawn increasing attention recently. But the class imbalance problem of the ramp event time series significantly affects the prediction accuracy of ramp events. In the present study, a layer oversampling (LOS) method is proposed considering the relation characteristics of wind power amplitudes and the occurrence frequency of wind power ramp events. Meanwhile, a hybrid sampling method of error bootstrap‐LOS (EB‐LOS) is proposed by combining LOS with the EB oversampling method. After balancing the samples of the ramp and nonramp events by using different sampling methods, the backpropagation neural network (BPNN), and the long short‐term memory (LSTM) methods are employed to directly predict ramp events based on historical data collected from eight wind farms. Comparison results proved that the proposed EB‐LOS method achieves the best prediction performance with an average recall of 0.8196 when using the BPNN model to directly predict ramp events. The best prediction performance of the EB‐LOS method is also proved by using the LSTM model to directly predict ramp events.
Keywords	class imbalance ; direct prediction ; layer oversampling ; ramp event ; relation characteristics ; wind power amplitudes ; Technology ; T ; Science ; Q
Subject code	650
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Point Projection Network

Weichao Wu / Zhong Xie / Yongyang Xu / Ziyin Zeng / Jie Wan

Remote Sensing, Vol 13, Iss 4917, p

A Multi-View-Based Point Completion Network with Encoder-Decoder Architecture

2021 Volume 4917

Abstract: Recently, unstructured 3D point clouds have been widely used in remote sensing application. However, inevitable is the appearance of an incomplete point cloud, primarily due to the angle of view and blocking limitations. Therefore, point cloud completion ...

Abstract	Recently, unstructured 3D point clouds have been widely used in remote sensing application. However, inevitable is the appearance of an incomplete point cloud, primarily due to the angle of view and blocking limitations. Therefore, point cloud completion is an urgent problem in point cloud data applications. Most existing deep learning methods first generate rough frameworks through the global characteristics of incomplete point clouds, and then generate complete point clouds by refining the framework. However, such point clouds are undesirably biased toward average existing objects, meaning that the completion results lack local details. Thus, we propose a multi-view-based shape-preserving point completion network with an encoder–decoder architecture, termed a point projection network (PP-Net). PP-Net completes and optimizes the defective point cloud in a projection-to-shape manner in two stages. First, a new feature point extraction method is applied to the projection of a point cloud, to extract feature points in multiple directions. Second, more realistic complete point clouds with finer profiles are yielded by encoding and decoding the feature points from the first stage. Meanwhile, the projection loss in multiple directions and adversarial loss are combined to optimize the model parameters. Qualitative and quantitative experiments on the ShapeNet dataset indicate that our method achieves good results in learning-based point cloud shape completion methods in terms of chamfer distance (CD) error. Furthermore, PP-Net is robust to the deletion of multiple parts and different levels of incomplete data.
Keywords	3D point clouds ; shape completion ; deep learning ; multi-view-based methods ; Science ; Q
Subject code	006
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Spatiotemporal Diurnal Modulation Characteristic of Wind Speed and Power Generation Revealed by Its Measured Data Processing

Jie Wan / Kun Yao / Guorui Ren / Ke Han / Qi Wang / Jilai Yu

Computational Intelligence and Neuroscience, Vol

2022 Volume 2022

Abstract: Atmospheric turbulence is an intrinsic factor that causes uncertainty of wind speed and its power generation by wind turbine. The research of atmospheric turbulence characteristics of wind farms can be used to reduce this uncertainty. In this paper, ... ...

Abstract	Atmospheric turbulence is an intrinsic factor that causes uncertainty of wind speed and its power generation by wind turbine. The research of atmospheric turbulence characteristics of wind farms can be used to reduce this uncertainty. In this paper, enough measurement data getting from actual wind farms is used for information processing to quantitatively analyze the daily variation of wind speed and its power output characteristics. Furthermore, the concept of spatiotemporal diurnal modulation characteristics of atmospheric turbulence is proposed with a global scope, which is an intrinsic property of wind. Besides the daily variation characteristics, the average hourly wind speed has a short-term modulation effect on its turbulence and provides a modulation characteristic on wind speed uncertainty. Moreover, the long-term modulation process is affected by seasonal and regional factors, indicating that it has spatiotemporal characteristics. This atmospheric turbulence characteristic has similar effects on characteristic description parameters. However, the characteristics description parameters of wind speed and wind power variation fail to reflect such intrinsic characteristics that are not affected by the spatiotemporal diurnal modulation characteristics of atmospheric turbulence. This indicates that they do not have diurnal characteristics. Finally, a time-varying model combined with the spatiotemporal diurnal modulation characteristics of wind speed and its power generation is discussed by applying on the evaluation of frequency control in power systems. It is shown that the results obtained by measured data processing could improve the power generation quality of large-scale wind power effectively.
Keywords	Computer applications to medicine. Medical informatics ; R858-859.7 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571
Subject code	551 ; 621
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Evolution of the combined effect of different irrigation solutions and activation techniques on the removal of smear layer and dentin microhardness in oval-shaped root canal – An in-vitro study

Lu Shi / Jie Wan / Yunfei Yang / Ying Yao / Ruiming Yang / Wen Xie

Bosnian Journal of Basic Medical Sciences (2022)

2022

Abstract: The aim of this in vitro study was to evaluate the effect of three final irrigants, namely QMix, MTAD and EDTA, combined with three irrigation techniques, namely conventional needle irrigation (CNI), passive ultrasonic irrigation (PUI) and photon-induced ...

Abstract	The aim of this in vitro study was to evaluate the effect of three final irrigants, namely QMix, MTAD and EDTA, combined with three irrigation techniques, namely conventional needle irrigation (CNI), passive ultrasonic irrigation (PUI) and photon-induced photoacoustic streaming (PIPS), on smear layer removal, dentin mineral content and microhardness in oval-shaped canals. 130 decoronated premolars with single, oval root canals were equally divided into1 blank control group and 12 treatment groups (n=10) according to the final irrigation protocols. Roots in treatment groups were instrumented with ProTaper Gold to size F4 and subjected to final irrigation. Smear layer removal was assessed by using a four-level scoring system under an environmental scanning electron microscope. Energy dispersive X-ray spectroscopy was performed to measure the dentin mineral content. Dentin microhardness was measured by Knoop microhardness testing. Statistical analysis of the data was performed by using Kruskal-Wallis test, followed by Dunn’s post hoc test with Bonferroni correction. PUI- and PIPS-activated QMix and EDTA removed smear layer more effectively than MTAD groups (p<0.05). Regarding the dentin mineral content and microhardness, QMix groups yielded the least calcium (Ca), phosphorus (P) and Ca/P ratio, followed by EDTA groups and MTAD groups (p<0.05). QMix groups produced significantly lower dentin microhardness values and higher hardness reduction percentages than MTAD groups (p<0.05). Within the limitations of the present study, it was concluded that QMix and EDTA were superior to MTAD in smear layer removal, especially when activated by PUI and PIPS, but these agents produced more pronounced effect on dentin mineral content and microhardness than MTAD.
Keywords	Root canal therapy ; photon-induced photoacoustic streaming ; passive ultrasonic irrigation ; smear layer ; dentin microhardness ; Medicine (General) ; R5-920
Subject code	571
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Evolution of the combined effect of different irrigation solutions and activation techniques on the removal of smear layer and dentin microhardness in oval-shaped root canal – An in-vitro study

Lu Shi / Jie Wan / Yunfei Yang / Ying Yao / Ruiming Yang / Wen Xie

Bosnian Journal of Basic Medical Sciences (2022)

2022

Abstract	The aim of this in vitro study was to evaluate the effect of three final irrigants, namely QMix, MTAD and EDTA, combined with three irrigation techniques, namely conventional needle irrigation (CNI), passive ultrasonic irrigation (PUI) and photon-induced photoacoustic streaming (PIPS), on smear layer removal, dentin mineral content and microhardness in oval-shaped canals. 130 decoronated premolars with single, oval root canals were equally divided into1 blank control group and 12 treatment groups (n=10) according to the final irrigation protocols. Roots in treatment groups were instrumented with ProTaper Gold to size F4 and subjected to final irrigation. Smear layer removal was assessed by using a four-level scoring system under an environmental scanning electron microscope. Energy dispersive X-ray spectroscopy was performed to measure the dentin mineral content. Dentin microhardness was measured by Knoop microhardness testing. Statistical analysis of the data was performed by using Kruskal-Wallis test, followed by Dunn’s post hoc test with Bonferroni correction. PUI- and PIPS-activated QMix and EDTA removed smear layer more effectively than MTAD groups (p<0.05). Regarding the dentin mineral content and microhardness, QMix groups yielded the least calcium (Ca), phosphorus (P) and Ca/P ratio, followed by EDTA groups and MTAD groups (p<0.05). QMix groups produced significantly lower dentin microhardness values and higher hardness reduction percentages than MTAD groups (p<0.05). Within the limitations of the present study, it was concluded that QMix and EDTA were superior to MTAD in smear layer removal, especially when activated by PUI and PIPS, but these agents produced more pronounced effect on dentin mineral content and microhardness than MTAD.
Keywords	Root canal therapy ; photon-induced photoacoustic streaming ; passive ultrasonic irrigation ; smear layer ; dentin microhardness ; Medicine (General) ; R5-920
Subject code	571
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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