LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 3 of total 3

Search options

  1. Article: A prospective randomized double-blind study comparing the dose-response curves of epidural ropivacaine for labor analgesia initiation between parturients with and without obesity.

    Huang, Xiao-Dong / Qiu, Xiao-Xiao / Wang, He-Jie / Jin, Xia-Fang / Xiao, Fei

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1348700

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1348700
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Dose-Response Study of Phenylephrine for Preventing Spinal-Induced Hypotension During Cesarean Delivery with Combined Spinal-Epidural Anesthesia Under the Effect of Prophylactic Intravenous Ondansetron.

    Sun, Xiao-Xia / Qian, Jing / Fan, Jia-Ming / Liu, Lin / Jin, Xia-Fang / Xiao, Fei

    Drug design, development and therapy

    2024  Volume 18, Page(s) 1459–1467

    Abstract: Background: Ondansetron reduces the median effective dose (ED50) of prophylactic phenylephrine to prevent spinal-induced hypotension (SIH) during cesarean delivery. However, the exact dose response of phenylephrine in combination with prophylactic ... ...

    Abstract Background: Ondansetron reduces the median effective dose (ED50) of prophylactic phenylephrine to prevent spinal-induced hypotension (SIH) during cesarean delivery. However, the exact dose response of phenylephrine in combination with prophylactic ondansetron for preventing SIH is unknown. Therefore, this study aimed to determine the dose-response of phenylephrine to prevent SIH in cesarean delivery when 4 mg of ondansetron was used as a preventive method.
    Methods: A total of 80 parturients were enrolled and divided randomly into four groups (n = 20 in each group) who received either 0.2, 0.3, 0.4, or 0.5 μg/kg/min of prophylactic phenylephrine. Ten minutes before the initiation of spinal induction, 4 mg prophylactic ondansetron was administered. The effective dose of prophylactic phenylephrine was defined as the dose required to prevent hypotension after the period of intrathecal injection and up to neonatal delivery. The ED50 and ED90 of prophylactic phenylephrine and 95% confidence intervals (95% CI) were calculated using probit analysis.
    Results: The ED50 and ED90 for prophylactic phenylephrine to prevent SIH were 0.25 (95% CI, 0.15 to 0.30), and 0.45 (95% CI, 0.39 to 0.59) μg/kg/min, respectively. No significant differences were observed in the side effects and neonatal outcomes between the four groups.
    Conclusion: The administration of 4 mg of prophylactic ondansetron was associated with an ED50 of 0.25 (95% CI, 0.15~0.30) and ED90 of 0.45 (95% CI, 0.39~0.59) μg/kg/min for phenylephrine to prevent SIH.
    MeSH term(s) Phenylephrine/administration & dosage ; Ondansetron/administration & dosage ; Humans ; Cesarean Section ; Hypotension/prevention & control ; Hypotension/chemically induced ; Female ; Dose-Response Relationship, Drug ; Anesthesia, Spinal/adverse effects ; Adult ; Pregnancy ; Anesthesia, Epidural
    Chemical Substances Phenylephrine (1WS297W6MV) ; Ondansetron (4AF302ESOS)
    Language English
    Publishing date 2024-04-30
    Publishing country New Zealand
    Document type Journal Article ; Randomized Controlled Trial ; Case Reports ; Clinical Trial
    ZDB-ID 2451346-5
    ISSN 1177-8881 ; 1177-8881
    ISSN (online) 1177-8881
    ISSN 1177-8881
    DOI 10.2147/DDDT.S452983
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: TCF21

    Wang, Jian-Guo / Jin, Xia-Fang / Huang, Yi-Min / Xu, Zheng-Fen / Huang, Shou-Ju / Zhu, Yingjie / Ai, Ling / Hang, Tian

    Biomarkers in medicine

    2024  Volume 17, Issue 17, Page(s) 693–699

    Abstract: Aims: ...

    Abstract Aims:
    MeSH term(s) Humans ; Case-Control Studies ; Genotype ; Polymorphism, Single Nucleotide ; Colorectal Neoplasms/genetics ; China ; Basic Helix-Loop-Helix Transcription Factors/genetics
    Chemical Substances TCF21 protein, human ; Basic Helix-Loop-Helix Transcription Factors
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2481014-9
    ISSN 1752-0371 ; 1752-0363
    ISSN (online) 1752-0371
    ISSN 1752-0363
    DOI 10.2217/bmm-2022-0750
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6985: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top