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  1. Article ; Online: Prevalence of cognitive frailty among older adults in China

    Jian Liu / Zhiwei Wang / Qian Liang / Shengjia Xu / Jiurui Wang / Zeping Yan / Xiaorong Luan

    BMJ Open, Vol 13, Iss

    a systematic review and meta-analysis

    2023  Volume 4

    Abstract: Objective This study aimed to investigate the prevalence of cognitive frailty among older adults in China.Design Systematic review and meta-analysis.Methods We searched the Cochrane Library, PubMed, Web of Science, Embase, China National Knowledge ... ...

    Abstract Objective This study aimed to investigate the prevalence of cognitive frailty among older adults in China.Design Systematic review and meta-analysis.Methods We searched the Cochrane Library, PubMed, Web of Science, Embase, China National Knowledge Infrastructure(CNKI), Wanfang, Chinese Biomedical Literature and Weipu (VIP) databases to collect information on the epidemiology of cognitive frailty among older adults in China. The study period was from the establishment of the database to March 2022. Two researchers independently screened the literature, extracted the data and assessed the risk of bias in the included studies. All statistical analyses were performed using Stata V.15.0.Results We screened 522 records, of which 28 met the inclusion criteria. The results of the meta-analysis showed that the prevalence of cognitive frailty among older adults in China was 15%(95%CI (0.13%,0.17%)). The prevalence of cognitive frailty was higher in hospitals and nursing homes than in communities. Moreover, the prevalence of cognitive frailty was higher in women than in men. Furthermore, the prevalence rates of cognitive frailty in North China Hospital, older adults aged≥80 years, and illiterate individuals were 25%, 29%, and 55%, respectively.Conclusions In conclusion, in China, the prevalence of cognitive frailty is higher among older adults, is higher in women than in men, is higher in hospitals and nursing homes than in communities, and is higher in North China than other regions. Moreover, the higher the educational level, the lower the prevalence of cognitive frailty. Multimodal interventions for cognitive frailty, including increased exercise, nutritional support, increased socialisation opportunities and multifactorial strategies, may be effective in preventing cognitive frailty. These findings have important implications for adjusting healthcare and social care systems.PROSPERO registration number CRD42023390486.
    Keywords Medicine ; R
    Subject code 950
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Genetic analysis of mixed models of fruit sugar-acid fractions in a cross between jujube (

    Zhi, Yang / Chuanjiang, Zhang / Xinfang, Yang / Mengyi, Dong / Zhenlei, Wang / Fenfen, Yan / Cuiyun, Wu / Jiurui, Wang / Mengjun, Liu / Minjuan, Lin

    Frontiers in plant science

    2023  Volume 14, Page(s) 1181903

    Abstract: Chinese jujube ( ...

    Abstract Chinese jujube (
    Language English
    Publishing date 2023-05-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1181903
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Genome-wide identification, characterization of the MADS-box gene family in Chinese jujube and their involvement in flower development

    Liman Zhang / Jin Zhao / Chunfang Feng / Mengjun Liu / Jiurui Wang / Yafei Hu

    Scientific Reports, Vol 7, Iss 1, Pp 1-

    2017  Volume 13

    Abstract: Abstract MADS-box genes encode transcription factors that are involved in plant development control (particularly in floral organogenesis) and signal transduction pathways, though a comprehensive analysis of MADS-box family proteins in Chinese jujube ( ... ...

    Abstract Abstract MADS-box genes encode transcription factors that are involved in plant development control (particularly in floral organogenesis) and signal transduction pathways, though a comprehensive analysis of MADS-box family proteins in Chinese jujube (Ziziphus jujuba Mill.) is still missing. Here, we report a genome-wide analysis of the MADS-box gene family in Chinese jujube. Based on phylogenetic analyses, 52 jujube MADS-box genes were classified into 25 MIKCC-type, 3 MIKC*-type, 16 Mα, 5 Mβ and 3 Mγ genes. 37 genes were randomly distributed across all 12 putative chromosomes. We found that the type II genes are more complex than the type I genes and that tandem duplications have occurred in three groups of MADS-box genes. Meanwhile, some gene pairs in the same clade displayed similar or distinct expression profiles, suggesting possible functional redundancy or divergence. MIKCC-type genes exhibited typical temporal and spatial expression patterns in the four whorls of floral tissues. The expressions of B, C/D and E-type genes were significantly suppressed in phyllody as compared to flower, providing valuable evidence for their involvement in flower development. This study is the first comprehensive analysis of the MADS-box family in jujube, and provides valuable information for elucidating molecular regulation mechanism of jujube flower development.
    Keywords Medicine ; R ; Science ; Q
    Subject code 572
    Language English
    Publishing date 2017-04-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Phylogenetic analysis of 25 plant species representing 19 angiosperm families and one gymnosperm family based on 390 orthologous genes

    Liu, Mengjun / Jin Zhao / Jiurui Wang / Zhiguo Liu / Guocheng Liu

    Plant systematics and evolution. 2017 Mar., v. 303, no. 3

    2017  

    Abstract: High-throughput sequencing is fundamentally altering traditional phylogenetic classifications. While the Angiosperm Phylogeny Group (APG) III system based on chloroplast sequences has opened up a new era of angiosperm molecular classification, the use of ...

    Abstract High-throughput sequencing is fundamentally altering traditional phylogenetic classifications. While the Angiosperm Phylogeny Group (APG) III system based on chloroplast sequences has opened up a new era of angiosperm molecular classification, the use of nuclear genome sequences is more helpful for a precise phylogenetic analysis. However, such attempts have so far been applied to only a very limited number of angiosperm plant families. We constructed a phylogenetic tree of 25 plant species with well assembled genome sequences representing 19 angiosperm families and one gymnosperm family (as out group) using 390 orthologous genes. Our results strongly support the moving of Rhamnaceae to order Rosales from Rhamnales, abolishing Rhamnales, and establishing the new order Malpighiales in the APG III system. Our data also showed some characteristics inconsistent with the APG III classification and provided a reinterpretation of phylogeny for some of the families involved. We propose that Malpighiales should be placed in Malvids, not Fabids. The four monocot species representing four families were clustered together, indicating that monocot is a natural taxon. In summary, our results support almost all the APGIII treatments of the orders involved in this study and provided some surprising reinterpretations at levels beyond order.
    Keywords Gymnospermae ; Liliopsida ; Malpighiales ; Rhamnaceae ; chloroplasts ; genes ; high-throughput nucleotide sequencing ; new order ; nuclear genome ; nucleotide sequences ; organisms ; phylogeny
    Language English
    Dates of publication 2017-03
    Size p. 413-417.
    Publishing place Springer Vienna
    Document type Article
    ZDB-ID 1463027-8
    ISSN 1615-6110 ; 0378-2697
    ISSN (online) 1615-6110
    ISSN 0378-2697
    DOI 10.1007/s00606-016-1380-9
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: In Vivo Fast Induction of Homogeneous Autopolyploids via Callus in Sour Jujube (Ziziphus acidojujuba Cheng et Liu)

    Shi, Qinghua / Jin Zhao / Jiurui Wang / Li Dai / Mengjun Liu / Ping Liu / Zhihui Zhao

    Horticultural plant journal. 2016 May, v. 2, no. 3

    2016  

    Abstract: Polyploidization has been demonstrated as a very effective approach in fruit tree improvement. Sour jujube (Ziziphus acidojujuba Cheng et Liu) is a promising diploid wild, traditional fruit species (2n = 2x = 24) that is rich in vitamin C, which is the ... ...

    Abstract Polyploidization has been demonstrated as a very effective approach in fruit tree improvement. Sour jujube (Ziziphus acidojujuba Cheng et Liu) is a promising diploid wild, traditional fruit species (2n = 2x = 24) that is rich in vitamin C, which is the main rootstock of Chinese jujube (Z. jujuba Mill.). The novel method we developed for rapid in vivo induction of homogeneous autopolyploids (IVIHA) via callus in Chinese jujube was first applied and further optimized in sour jujube. Under optimized conditions, an average of one pure autotetraploid shoot could be regenerated from one treated branch, thereby indicating a relatively high efficiency rate. A total of 9 pure autotetraploid genotypes were created, and one of these was released as a new cultivar named ‘Zhuguang’ in 2015. Moreover, unexpected octoploids and hexaploids were also simultaneously created and detected. The leaves of tetraploids were thicker, broader, and darker in color than those of the original diploids, whereas the leaf sizes of octoploids were much smaller compared to that of diploids. However, stoma size increased with the occurrence of ploidy, mainly from diploid to octoploid. The well grown ploidies of jujube included diploids, triploids, and tetraploids. Anatomical observation indicated that adventitious buds/shoots emerged from the callus that formed on the cut, which was then followed by the development of connective vascular tissues between the adventitious bud and the stock plant tissue. This study demonstrates the universality of the IVIHA method that was initially developed in Chinese jujube, as well as provides a foundation for high-efficiency pure polyploid induction in sour jujube.
    Keywords ascorbic acid ; autotetraploidy ; buds ; callus ; color ; cultivars ; diploidy ; fruit trees ; fruits ; genotype ; hexaploidy ; leaves ; methodology ; octaploidy ; plant improvement ; rootstocks ; shoots ; triploidy ; vascular tissues ; Ziziphus jujuba
    Language English
    Dates of publication 2016-05
    Size p. 147-153.
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 2468-0141
    DOI 10.1016/j.hpj.2016.08.002
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: A novel in vivo shoot regeneration system via callus in woody fruit tree Chinese jujube (Ziziphus jujuba Mill.)

    Shi, Qinghua / Jiurui Wang / Juan Xu / Mengjun Liu / Ping Liu / Qiang Ning

    Scientia horticulturae. 2015 June 04, v. 188

    2015  

    Abstract: In vitro shoot regeneration system via callus is a widely used approach in fruit tree studies. However, it has some obvious limitations, such as high expenses associated with maintaining the sterile conditions, as well as long duration from in vitro ... ...

    Abstract In vitro shoot regeneration system via callus is a widely used approach in fruit tree studies. However, it has some obvious limitations, such as high expenses associated with maintaining the sterile conditions, as well as long duration from in vitro culture to field evaluation. After optimization of the key factors including growth regulator, callus induction time and branch diameter, we firstly established a high efficient in vivo callus induction and shoot regeneration system in Chinese jujube, a diploid woody fruit tree. Combining this new system with colchicine induction, pure polyploid could be easily created which could even bloom in the experimental year, at least 2 years earlier compared to the conventional in vitro polypoid induction approach. Furthermore, the new system is much simpler, less costly and more convenient. A wide range of applications in basic and applied researches, such as ploidy manipulation, genetic transformation and mutant induction, would become more efficient with this novel system.
    Keywords aseptic conditions ; callus ; colchicine ; diploidy ; genetic transformation ; growth regulators ; in vitro culture ; mutants ; polyploidy ; tree fruits ; Ziziphus jujuba
    Language English
    Dates of publication 2015-0604
    Size p. 30-35.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 185557-8
    ISSN 0304-4238
    ISSN 0304-4238
    DOI 10.1016/j.scienta.2015.03.013
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Rapid SNP discovery and a RAD-based high-density linkage map in jujube (Ziziphus Mill.).

    Jin Zhao / Jianbo Jian / Guannan Liu / Jiurui Wang / Minjuan Lin / Yao Ming / Zhiguo Liu / Yingying Chen / Xiuyun Liu / Mengjun Liu

    PLoS ONE, Vol 9, Iss 10, p e

    2014  Volume 109850

    Abstract: BACKGROUND: Ziziphus Mill. (jujube), the most valued genus of Rhamnaceae, comprises of a number of economically and ecologically important species such as Z. jujuba Mill., Z. acidojujuba Cheng et Liu and Z. mauritiana Lam. Single nucleotide polymorphism ( ...

    Abstract BACKGROUND: Ziziphus Mill. (jujube), the most valued genus of Rhamnaceae, comprises of a number of economically and ecologically important species such as Z. jujuba Mill., Z. acidojujuba Cheng et Liu and Z. mauritiana Lam. Single nucleotide polymorphism (SNP) markers and a high-density genetic map are of great benefit to the improvement of the crop, mapping quantitative trait loci (QTL) and analyzing genome structure. However, such a high-density map is still absent in the genus Ziziphus and even the family Rhamnaceae. The recently developed restriction-site associated DNA (RAD) marker has been proven to be most powerful in genetic map construction. The objective of this study was to construct a high-density linkage map using the RAD tags generated by next generation sequencing. RESULTS: An interspecific F1 population and their parents (Z. jujuba Mill. 'JMS2' × Z. acidojujuba Cheng et Liu 'Xing 16') were genotyped using a mapping-by-sequencing approach, to generate RAD-based SNP markers. A total of 42,784 putative high quality SNPs were identified between the parents and 2,872 high-quality RAD markers were grouped in genetic maps. Of the 2,872 RAD markers, 1,307 were linked to the female genetic map, 1,336 to the male map, and 2,748 to the integrated map spanning 913.87 centi-morgans (cM) with an average marker interval of 0.34 cM. The integrated map contained 12 linkage groups (LGs), consistent with the haploid chromosome number of the two parents. CONCLUSION: We first generated a high-density genetic linkage map with 2,748 RAD markers for jujube and a large number of SNPs were also developed. It provides a useful tool for both marker-assisted breeding and a variety of genome investigations in jujube, such as sequence assembly, gene localization, QTL detection and genome structure comparison.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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