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  1. Article ; Online: Minimally invasive vaginal approach to the uterovestibular anastomosis for cervicovaginal aplasia: a case series and review of literature.

    Mahajan, Niraj N / Tilve, Arundhati / Shinde, Ganesh / Jnanananda, Bhargavi / Saifi, Shenaz / Srivastava, Vartika / Bahirat, Shubhada / Srivastava, Shayla / Pophalkar, Madhura

    Archives of gynecology and obstetrics

    2022  Volume 308, Issue 1, Page(s) 25–34

    Abstract: Background: Congenital cervicovaginal agenesis (CVA) with functioning endometrium is an extremely rare mullerian anomaly. Genital tract patency and fertility preservation are the major challenges in cases of CVA. With the advances in surgical techniques, ...

    Abstract Background: Congenital cervicovaginal agenesis (CVA) with functioning endometrium is an extremely rare mullerian anomaly. Genital tract patency and fertility preservation are the major challenges in cases of CVA. With the advances in surgical techniques, management has shifted from a radical approach-like hysterectomy towards a more conservative approach of uterine conservation.
    Case presentation and review of the literature: In the present study, we report our experience in managing four cases of congenital CVA with complete vaginal atresia, which were treated with a simple minimally invasive vaginal approach for UVA without using graft for neovagina creation and studied the long-term anatomic and functional result of uterovestibular anastomosis (UVA) in patients with CVA. A literature review was performed for congenital complete vaginal atresia (≤ 2 cm blind vagina), with a functioning uterus. The experience and results of this 4-year study are in accordance with the prior studies with 97% (33/34) success rate, where vestibular mucosa was used for the UVA.
    Conclusions: Findings of this study should encourage more gynaecologists to learn and recreate a complete vaginal approach, as no special surgical equipments are needed. Hysterectomy should only be reserved for cases, where repeated anastomosis attempts fail. This minimally invasive technique should be preferred over canalization procedures and graft, as it is associated with a higher success rate with least complications and recurrence. Conservative end-to-end anastomosis with a completely vaginal approach should be offered as the primary treatment option for CVA with total vaginal atresia.
    MeSH term(s) Female ; Humans ; Cervix Uteri/surgery ; Cervix Uteri/abnormalities ; Uterus/surgery ; Uterus/abnormalities ; Vagina/surgery ; Vagina/abnormalities ; Anastomosis, Surgical/methods
    Language English
    Publishing date 2022-07-21
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-022-06708-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Increased spontaneous preterm births during the second wave of the coronavirus disease 2019 pandemic in India.

    Mahajan, Niraj N / Pednekar, Rahi / Gaikwad, Chaitanya / More, Prajakta / Pophalkar, Madhura / Kesarwani, Shweta / Jnanananda, Bhargavi / Mahale, Smita D / Gajbhiye, Rahul K

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2021  Volume 157, Issue 1, Page(s) 115–120

    Abstract: Objective: To compare spontaneous preterm birth (SPTB) and iatrogenic preterm birth (IPTB) rates during both waves of the coronavirus disease 2019 (COVID-19) pandemic.: Methods: Retrospective analysis of the PregCovid registry of pregnant women with ... ...

    Abstract Objective: To compare spontaneous preterm birth (SPTB) and iatrogenic preterm birth (IPTB) rates during both waves of the coronavirus disease 2019 (COVID-19) pandemic.
    Methods: Retrospective analysis of the PregCovid registry of pregnant women with COVID-19 was performed at a dedicated COVID-19 hospital in Mumbai, India. The data of 1630 women were analyzed for this study between April 4, 2020 and July 4, 2021. Prepandemic data were analyzed and compared with pandemic data. Main outcome measure was spontaneous preterm birth rate.
    Results: Preterm deliveries were higher during the second wave (46/329; 14%) compared with the first wave (82/807; 10.2%) of the COVID-19 pandemic (P = 0.065). Higher SPTBs were reported during the second wave than the first wave (12.5% versus 8.3%) (P = 0.03) as well as the prepandemic period (12.5% versus 10.5%) (P = 0.286). IPTBs were significantly lower in the pandemic period than in the prepandemic period (1.8 versus 3.3) (P = 0.012).
    Conclusion: In Mumbai, India, we found an unusual change in SPTBs during the 6 months of the second wave of COVID-19 compared with the previous 10 months of the first wave of pandemic and 1 year of prepandemic.
    MeSH term(s) COVID-19/epidemiology ; Female ; Humans ; Infant, Newborn ; Pandemics ; Pregnancy ; Premature Birth/epidemiology ; Retrospective Studies ; SARS-CoV-2
    Language English
    Publishing date 2021-11-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.13991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Impact of COVID-19 on pregnant women with Rheumatic heart disease or Peripartum cardiomyopathy.

    Tilve, Arundhati / Mahajan, Niraj N / Pandey, Ankita / Jnanananda, Bhargavi / Gadekar, Sangram / Mahale, Smita D / Gajbhiye, Rahul K

    European journal of obstetrics, gynecology, and reproductive biology

    2021  Volume 258, Page(s) 459–461

    MeSH term(s) Abnormalities, Multiple ; Adult ; COVID-19/complications ; COVID-19/physiopathology ; COVID-19/therapy ; Cardiomyopathies/complications ; Cardiomyopathies/diagnostic imaging ; Cardiomyopathies/drug therapy ; Cardiomyopathies/physiopathology ; Echocardiography ; Female ; Fetal Membranes, Premature Rupture ; Humans ; Infant, Low Birth Weight ; Infant, Newborn ; Perinatal Death ; Pregnancy ; Pregnancy Complications, Cardiovascular/diagnostic imaging ; Pregnancy Complications, Cardiovascular/drug therapy ; Pregnancy Complications, Cardiovascular/physiopathology ; Pregnancy Complications, Infectious/physiopathology ; Pregnancy Complications, Infectious/therapy ; Premature Birth ; Rheumatic Heart Disease/complications ; Rheumatic Heart Disease/diagnostic imaging ; Rheumatic Heart Disease/drug therapy ; Rheumatic Heart Disease/physiopathology ; Young Adult
    Language English
    Publishing date 2021-01-18
    Publishing country Ireland
    Document type Letter
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2021.01.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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