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Book: Discourse ability and brain damage

Joanette, Yves

theoretical and empirical perspectives

(Springer series in neuropsychology)

1990

Author's details	Yves Joanette ..., ed
Series title	Springer series in neuropsychology
Keywords	Brain Damage, Chronic / complications ; Brain Injuries / complications ; Language Disorders ; Neuropsychology ; Psycholinguistics ; Speech Disorders ; Hirnschädigung ; Sprachstörung ; Sprache ; Kommunikation ; Neurolinguistik
Subject	Neuropsychologie ; Sprachneurologie ; Kommunikationsprozess ; Informationsprozess ; Sprachen ; Sprachbehinderung ; Sprachfehler ; Cerebralschädigung ; Gehirn ; Hirnschaden ; Hirnläsion ; Zerebralschädigung
Language	English
Size	XVI, 258 S. : graph. Darst.
Publisher	Springer
Publishing place	New York u.a.
Publishing country	United States
Document type	Book
HBZ-ID	HT003502442
ISBN	0-387-97044-4 ; 3-540-97044-4 ; 978-0-387-97044-8 ; 978-3-540-97044-6
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

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1990 A 2569	order for loan	Magazin

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Article: Multifactorial approaches to study bilingualism in the aging population: Past, present, future.

Dash, Tanya / Joanette, Yves / Ansaldo, Ana Inés

Frontiers in psychology

2022 Volume 13, Page(s) 917959

Abstract: A better understanding and more reliable classification of bilinguals has been progressively achieved through the fine-tuning methodology and simultaneously optimizing the measurement tools. However, the current understanding is far from generalization ... ...

Abstract	A better understanding and more reliable classification of bilinguals has been progressively achieved through the fine-tuning methodology and simultaneously optimizing the measurement tools. However, the current understanding is far from generalization to a larger population varying in different measures of bilingualism-L2 Age of acquisition (L2 AOA), L2 usage and exposure, and L2 proficiency. More recent studies have highlighted the importance of modeling bilingualism as a continuous variable. An in-depth look at the role of bilingualism, comparing groups, may be considered a reductionist approach, i.e., grouping based on one measure of bilingualism (e.g., L2 AOA) may not account for variability in other measures of bilingualism (L2 exposure, L2 use or L2 proficiency, amongst others) within and between groups. Similarly, a multifactorial dimension is associated with cognitive performance, where not all domains of cognition and subcomponents are equally influenced by bilingualism. In addition, socio-cultural and demographical factors may add another dimension to the impact of bilingualism on cognitive performance, especially in older adults. Nevertheless, not many studies have controlled or used the multiple socio-cultural and demographical factors as a covariate to understand the role of different aspects of bilingualism that may influence cognitive performance differently. Such an approach would fail to generalize the research findings to a larger group of bilinguals. In the present review paper, we illustrate that considering a multifactorial approach to different dimensions of bilingual study may lead to a better understanding of the role of bilingualism on cognitive performance. With the evolution of various fine-tuned methodological approaches, there is a greater need to study variability in bilingual profiles that can help generalize the result universally.
Language	English
Publishing date	2022-07-29
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.917959
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Article ; Online: Exploring attention in the bilingualism continuum: A resting-state functional connectivity study.

Dash, Tanya / Joanette, Yves / Ansaldo, Ana Inés

Brain and language

2021 Volume 224, Page(s) 105048

Abstract: This study explores the effects of bilingualism on the subcomponents of attention using resting state functional connectivity analysis (rsFC). Unlike previous studies, measures of bilingualism - L2 Age of Acquisition (AOA), L2 exposure, and L2 ... ...

Abstract	This study explores the effects of bilingualism on the subcomponents of attention using resting state functional connectivity analysis (rsFC). Unlike previous studies, measures of bilingualism - L2 Age of Acquisition (AOA), L2 exposure, and L2 proficiency - were examined along a continuum to study attentional mechanisms using rsFC instead of dichotomizing them. 20 seed regions were pre-selected for the three subcomponents of attention. The results showed a positive association between behavioral performance and rsFC for the seeds in alerting and orienting network; this was not true for the seeds in the executive control network. Secondly, rsFC for attention networks varied with different levels of bilingualism. The objective measures of bilingualism modulate all three attention networks. While the subjective measures such as L2 AOA modulates specific attention network. Thus, language performance in contrast to self-reported information, as a measure of bilingualism, has a greater potential to tap into the role of bilingualism in attentional processes.
MeSH term(s)	Brain/diagnostic imaging ; Executive Function ; Humans ; Language ; Magnetic Resonance Imaging ; Multilingualism
Language	English
Publishing date	2021-11-13
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	7448-2
ISSN	1090-2155 ; 0093-934X
ISSN (online)	1090-2155
ISSN	0093-934X
DOI	10.1016/j.bandl.2021.105048
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Article ; Online: Living longer, living better: preview of CIHR Institute of Aging 2013-2018 strategic plan.

Joanette, Yves

Canadian journal on aging = La revue canadienne du vieillissement

2013 Volume 32, Issue 2, Page(s) 209–213

MeSH term(s)	Aging ; Canada ; Government Agencies/organization & administration ; Health Planning Organizations/organization & administration ; Health Services Research/organization & administration ; Humans
Language	English
Publishing date	2013-06
Publishing country	Canada
Document type	Journal Article
ZDB-ID	632851-9
ISSN	1710-1107 ; 0714-9808
ISSN (online)	1710-1107
ISSN	0714-9808
DOI	10.1017/S0714980813000226
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Article ; Online: Age-preserved semantic memory and the CRUNCH effect manifested as differential semantic control networks: An fMRI study.

Haitas, Niobe / Amiri, Mahnoush / Wilson, Maximiliano / Joanette, Yves / Steffener, Jason

PloS one

2021 Volume 16, Issue 6, Page(s) e0249948

Abstract: Semantic memory representations are overall well-maintained in aging whereas semantic control is thought to be more affected. To explain this phenomenon, this study aims to test the predictions of the Compensation Related Utilization of Neural Circuits ... ...

Abstract	Semantic memory representations are overall well-maintained in aging whereas semantic control is thought to be more affected. To explain this phenomenon, this study aims to test the predictions of the Compensation Related Utilization of Neural Circuits Hypothesis (CRUNCH) focusing on task demands in aging as a possible framework. The CRUNCH effect would manifest itself in semantic tasks through a compensatory increase in neural activation in semantic control network regions but only up to a certain threshold of task demands. This study will compare 40 young (20-35 years old) with 40 older participants (60-75 years old) in a triad-based semantic judgment task performed in an fMRI scanner while manipulating levels of task demands (low vs. high) through semantic distance. In line with the CRUNCH predictions, differences in neurofunctional activation and behavioral performance (accuracy and response times) are expected in young vs. old participants in the low- vs. high-demand conditions manifested in semantic control Regions of Interest.
MeSH term(s)	Adult ; Age Factors ; Aged ; Brain/physiology ; Brain Mapping/methods ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Memory/physiology ; Memory Disorders/diagnostic imaging ; Memory Disorders/physiopathology ; Middle Aged ; Psychomotor Performance/physiology ; Reaction Time/physiology ; Semantics
Language	English
Publishing date	2021-06-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0249948
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Article: Functional Connectivity of Successful Picture-Naming: Age-Specific Organization and the Effect of Engaging in Stimulating Activities.

Ferré, Perrine / Jarret, Julien / Brambati, Simona / Bellec, Pierre / Joanette, Yves

Frontiers in aging neuroscience

2020 Volume 12, Page(s) 535770

Abstract: Aging is a lifelong process that starts at birth. Throughout the course of their life, individuals are exposed to various levels of stimulating activities. A higher level of engagement in such activities is suspected to protect against the normal course ... ...

Abstract	Aging is a lifelong process that starts at birth. Throughout the course of their life, individuals are exposed to various levels of stimulating activities. A higher level of engagement in such activities is suspected to protect against the normal course of cognitive aging or the cognitive manifestations of age-related brain diseases. However, the exact mechanism underlying such protective action remains unclear. The concept of the neurocognitive reserve was introduced to refer to the hypothesis that engagement in stimulating activities shapes brain structure and function, thus indirectly allowing for better preserved cognitive abilities. Although it is known that word production is among the best-preserved cognitive abilities in aging, the underlying neurofunctional mechanisms that allow this relative preservation are still unknown, and it is still unclear how engagement in stimulating activities affects these processes. The objective of this study is to describe the brain functional connectivity patterns associated with picture-naming abilities in younger and older adults with varying levels of engagement in stimulating activities, as a proxy for neurocognitive reserve. A mediation analysis was applied to determine whether the association between reserve proxies and naming accuracy is dependent on task FC. Results show that naming accuracy depends on the posterior cingulate cortex (PCC) functional decoupling in both younger and older adults but through different pathways. While high-performing older adults rely on the asynchronization of this area from motor speech regions' activity, the best-performing younger adults rely on the functional decoupling with language-related regions. Mediation analysis reveals that the PCC decoupling mediates the relationship between the level of engagement in stimulating activities and naming accuracy in younger adults, but not in older adults. These findings suggest that reserve-related mechanisms may be more critical for naming in early adult life, while older adults' neurofunctional organization may benefit more from a lifetime of acquired knowledge.
Language	English
Publishing date	2020-11-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2558898-9
ISSN	1663-4365
ISSN	1663-4365
DOI	10.3389/fnagi.2020.535770
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Article ; Online: Considerations about cognitive communication deficits following COVID-19.

Khatoonabadi, Ahmad Reza / Joanette, Yves / Nitsche, Michael Andreas / Ansaldo, Ana Ines

Psychiatry and clinical neurosciences

2020 Volume 74, Issue 12, Page(s) 662–663

MeSH term(s)	COVID-19/complications ; COVID-19/rehabilitation ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/rehabilitation ; Communication Aids for Disabled ; Communication Disorders/etiology ; Communication Disorders/rehabilitation ; Delirium/etiology ; Delirium/rehabilitation ; Humans ; Intensive Care Units ; Mental Status and Dementia Tests
Keywords	covid19
Language	English
Publishing date	2020-10-12
Publishing country	Australia
Document type	Letter
ZDB-ID	1292906-2
ISSN	1440-1819 ; 1323-1316
ISSN (online)	1440-1819
ISSN	1323-1316
DOI	10.1111/pcn.13159
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Article ; Online: Cortical thinning is associated with brain pulsatility in older adults: An MRI and NIRS study.

Mohammadi, Hanieh / Peng, Ke / Kassab, Ali / Nigam, Anil / Bherer, Louis / Lesage, Frédéric / Joanette, Yves

Neurobiology of aging

2021 Volume 106, Page(s) 103–118

Abstract: Aging is accompanied by global brain atrophy occurring unequally across the brain. Cortical thinning is seen with aging with a larger loss in the frontal and temporal subregions. We explored the link between regional cortical thickness and regional ... ...

Abstract	Aging is accompanied by global brain atrophy occurring unequally across the brain. Cortical thinning is seen with aging with a larger loss in the frontal and temporal subregions. We explored the link between regional cortical thickness and regional cerebral pulsatility. Sixty healthy individuals were divided into two age groups, young (aged 19-31) and older (aged 65-75) adults. Each participant underwent a near-infrared spectroscopy (NIRS) scan to index regional brain pulsatility from cerebral pulse-transit-time-to-the peak-of-the-pulse (PTTp), an anatomical magnetic resonance imaging (MRI) and a phase-contrast MRI (PC-MRI) scan to measure arterial and cerebrospinal fluid (CSF) pulsatility. In older adults, the greatest association between cerebral pulsatility and cortical thickness was found in superior and middle temporal and superior, middle and inferior frontal areas, which are the regions perfused first by the internal carotid arteries. This association dropped in the postcentral and superior parietal regions. These findings suggest higher brain pulsatility as a potential risk factor contributing to cortical thinning for some brain regions more than others.
MeSH term(s)	Adult ; Aged ; Aging/pathology ; Aging/physiology ; Carotid Artery, Internal/physiology ; Cerebral Cortex/blood supply ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/pathology ; Cerebral Cortex/physiology ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/pathology ; Cognitive Dysfunction/physiopathology ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Neuroimaging/methods ; Pulsatile Flow/physiology ; Risk Factors ; Spectroscopy, Near-Infrared/methods ; Young Adult
Language	English
Publishing date	2021-05-24
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	604505-4
ISSN	1558-1497 ; 0197-4580
ISSN (online)	1558-1497
ISSN	0197-4580
DOI	10.1016/j.neurobiolaging.2021.05.002
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Article ; Online: Considerations about Cognitive‐Communication deficits following COVID‐19

Khatoonabadi, Ahmad Reza / Joanette, Yves / Nitsche, Michael Andreas

Psychiatry and Clinical Neurosciences ; ISSN 1323-1316 1440-1819

2020

Keywords	General Neuroscience ; Neurology ; Psychiatry and Mental health ; Clinical Neurology ; General Medicine ; covid19
Language	English
Publisher	Wiley
Publishing country	us
Document type	Article ; Online
DOI	10.1111/pcn.13159
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Age, multimorbidity and dementia with health care costs in older people in Alberta: a population-based retrospective cohort study.

Tonelli, Marcello / Wiebe, Natasha / Joanette, Yves / Hemmelgarn, Brenda R / So, Helen / Straus, Sharon / James, Matthew T / Manns, Braden J / Klarenbach, Scott W

CMAJ open

2022 Volume 10, Issue 3, Page(s) E577–E588

Abstract: Background: The growing burden associated with population aging, dementia and multimorbidity poses potential challenges for the sustainability of health systems worldwide. We sought to examine how the intersection among age, dementia and greater ... ...

Abstract	Background: The growing burden associated with population aging, dementia and multimorbidity poses potential challenges for the sustainability of health systems worldwide. We sought to examine how the intersection among age, dementia and greater multimorbidity is associated with health care costs. Methods: We did a retrospective population-based cohort study in Alberta, Canada, with adults aged 65 years and older between April 2003 and March 2017. We identified 31 morbidities using algorithms (30 algorithms were validated), which were applied to administrative health data, and assessed costs associated with hospital admission, provider billing, ambulatory care, medications and long-term care (LTC). Actual costs were used for provider billing and medications; estimated costs for inpatient and ambulatory patients were based on the Canadian Institute for Health Information's resource intensive weights and Alberta's cost of a standard hospital stay. Costs for LTC were based on an estimated average daily cost. Results: There were 827 947 people in the cohort. Dementia was associated with higher mean annual total costs and individual mean component costs for almost all age categories and number of comorbidities categories (differences in total costs ranged from $27 598 to $54 171). Similarly, increasing number of morbidities was associated with higher mean total costs and component costs (differences in total costs ranged from $4597 to $10 655 per morbidity). Increasing age was associated with higher total costs for people with and without dementia, driven by increasing LTC costs (differences in LTC costs ranged from $115 to $9304 per age category). However, there were no consistent trends between age and non-LTC costs among people with dementia. When costs attributable to LTC were excluded, older age tended to be associated with lower costs among people with dementia (differences in non-LTC costs ranged from -$857 to -$7365 per age category). Interpretation: Multimorbidity, older age and dementia were all associated with increased use of LTC and thus health care costs, but some costs among people with dementia decreased at older ages. These findings illustrate the complexity of projecting the economic consequences of the aging population, which must account for the interplay between multimorbidity and dementia.
MeSH term(s)	Adult ; Aged ; Alberta/epidemiology ; Cohort Studies ; Dementia/epidemiology ; Dementia/therapy ; Health Care Costs ; Humans ; Multimorbidity ; Retrospective Studies
Language	English
Publishing date	2022-07-05
Publishing country	Canada
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2701622-5
ISSN	2291-0026 ; 2291-0026
ISSN (online)	2291-0026
ISSN	2291-0026
DOI	10.9778/cmajo.20210035
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