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Article ; Online: CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels.

Gonçalves, André Brás / Hasselbalch, Sarah Kirstine / Joensen, Beinta Biskopstø / Patzke, Sebastian / Martens, Pernille / Ohlsen, Signe Krogh / Quinodoz, Mathieu / Nikopoulos, Konstantinos / Suleiman, Reem / Damsø Jeppesen, Magnus Per / Weiss, Catja / Christensen, Søren Tvorup / Rivolta, Carlo / Andersen, Jens S / Farinelli, Pietro / Pedersen, Lotte Bang

eLife

2021  Volume 10

Abstract: CEP78 is a centrosomal protein implicated in ciliogenesis and ciliary length control, and mutations in ... ...

Abstract CEP78 is a centrosomal protein implicated in ciliogenesis and ciliary length control, and mutations in the
MeSH term(s) Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cilia/metabolism ; Gene Knockout Techniques ; Humans ; Microtubule Proteins/genetics ; Microtubule Proteins/metabolism ; Microtubule-Associated Proteins/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Phosphoproteins/metabolism ; Ubiquitination
Chemical Substances CCP110 protein, human ; CEP350 protein, human ; CEP78 protein, human ; Cell Cycle Proteins ; Microtubule Proteins ; Microtubule-Associated Proteins ; Nuclear Proteins ; Phosphoproteins
Language English
Publishing date 2021-07-14
Publishing country England
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 2687154-3
ISSN 2050-084X ; 2050-084X
ISSN (online) 2050-084X
ISSN 2050-084X
DOI 10.7554/eLife.63731
Database MEDical Literature Analysis and Retrieval System OnLINE

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