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Article ; Online: Supercoiling and looping promote DNA base accessibility and coordination among distant sites

Jonathan M. Fogg / Allison K. Judge / Erik Stricker / Hilda L. Chan / Lynn Zechiedrich

Nature Communications, Vol 12, Iss 1, Pp 1-

2021  Volume 16

Abstract: DNA supercoiling can result in underwinding with negative supercoiling or overwinding with positive supercoiling of the DNA double helix. Here the authors reveal insights into the dynamic relationship between DNA supercoiling-induced sequence-dependent ... ...

Abstract DNA supercoiling can result in underwinding with negative supercoiling or overwinding with positive supercoiling of the DNA double helix. Here the authors reveal insights into the dynamic relationship between DNA supercoiling-induced sequence-dependent disruptions to base pairing, DNA looping, and the shape of the DNA molecule.
Keywords Science ; Q
Language English
Publishing date 2021-09-01T00:00:00Z
Publisher Nature Portfolio
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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