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  1. Article ; Online: Tune-In and Time-Out: Toward Surgeon-Led Prevention of "Never" Events.

    Jones, Niall

    Journal of patient safety

    2016  Volume 15, Issue 4, Page(s) e36–e39

    Abstract: Introduction: The World Health Organization (WHO) distributed a surgical safety checklist in 2008 in a bid to improve patient safety and quality of care in the operating theater. Adherence to the checklist has been shown to reduce "never" events, for ... ...

    Abstract Introduction: The World Health Organization (WHO) distributed a surgical safety checklist in 2008 in a bid to improve patient safety and quality of care in the operating theater. Adherence to the checklist has been shown to reduce "never" events, for example, wrong site surgery. The aim of this quality improvement study was to determine the current adherence by surgeons to the checklist at The Royal Hobart Hospital.
    Methods: This is a retrospective audit of the digital medical records of 100 consecutive emergency operations performed at The Royal Hobart Hospital. The time-out section of the WHO Surgical Safety Checklist was assessed for completeness. Second, an anonymized survey of theater nursing staff was performed to determine current adherence by surgeons with the time-out.
    Results: The time-out was completed in 79% of emergency procedures. There were no never events in the patient cohort studied. There was overwhelming support among theater nurses for a surgeon-led time-out. Formal education on the use of the WHO Safe Surgery Checklist is lacking. Most theater nurses have experienced hostility from surgeons when conducting a time-out.
    Discussion: This work is a step on the way to surgeon-led prevention of never events. Finding a completed time-out in the patient notes does not guarantee surgeon support for or contribution to the time-out process. The findings will inform combined nursing and surgeon education sessions, and together with executive-level support, improved surgeon cooperation with the time-out will inculcate a culture of safety for patients and improve harmony among staff groups.
    MeSH term(s) Checklist ; Cohort Studies ; Emergencies ; Guideline Adherence ; Hospitals ; Humans ; Leadership ; Medical Errors/prevention & control ; Nursing Staff ; Operating Room Nursing ; Operating Rooms ; Patient Safety/standards ; Physician-Nurse Relations ; Professional Role ; Quality Improvement ; Retrospective Studies ; Safety Management ; Surgeons ; Surveys and Questionnaires
    Language English
    Publishing date 2016-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2394324-5
    ISSN 1549-8425 ; 1549-8417
    ISSN (online) 1549-8425
    ISSN 1549-8417
    DOI 10.1097/PTS.0000000000000259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Epidemiology and outcomes of gastroschisis in Tasmania.

    Hariharan, Gopakumar / Jones, Niall / Ee, Michael / De Paoli, Antonio

    Journal of paediatrics and child health

    2020  Volume 56, Issue 11, Page(s) 1795–1798

    Abstract: Aim: To describe the epidemiology and outcomes of gastroschisis in Tasmania.: Methods: A retrospective analysis of all pregnancies complicated by gastroschisis in Tasmania from 1996 to 2015 was undertaken (epidemiology cohort), and the presentation, ... ...

    Abstract Aim: To describe the epidemiology and outcomes of gastroschisis in Tasmania.
    Methods: A retrospective analysis of all pregnancies complicated by gastroschisis in Tasmania from 1996 to 2015 was undertaken (epidemiology cohort), and the presentation, surgical management and outcomes (surgery cohort) were reviewed for the period between September 1990 and July 2015.
    Results: Gastroschisis was detected in 58 pregnancies during the 20-year epidemiology cohort period, giving an incidence of 4.4 per 10 000 live births for the 20-year period. Two of the four stillbirths occurred after 36 weeks' gestation. Of the 65 babies with gastroschisis treated at the Royal Hobart Hospital, 51 had a staged surgical repair (silo in 47, stoma formation in 4), and 14 had a primary closure. Staged repair was associated with a significantly longer duration of ventilation and stay in the neonatal intensive care unit. There were six post-natal deaths, all born in the first epoch. Death was significantly associated with the condition of the intestine at delivery (P = 0.02). There were no deaths in babies with simple gastroschisis. Complex gastroschisis was significantly associated with longer duration of total parenteral nutrition (P = 0.0002) and longer stay in hospital (P = 0.03).
    Conclusions: The incidence of gastroschisis in Tasmania is similar to that reported in other Australian regions and has not increased over the 20-year period of study. The high risk of stillbirth, and the significant association between mortality and the condition of the intestine at birth necessitates close fetal surveillance. Complex gastroschisis imposes a significant burden on hospital resources.
    MeSH term(s) Australia/epidemiology ; Female ; Gastroschisis/epidemiology ; Gastroschisis/surgery ; Gestational Age ; Humans ; Infant, Newborn ; Length of Stay ; Pregnancy ; Retrospective Studies ; Tasmania/epidemiology ; Treatment Outcome
    Language English
    Publishing date 2020-03-20
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1024476-1
    ISSN 1440-1754 ; 1034-4810
    ISSN (online) 1440-1754
    ISSN 1034-4810
    DOI 10.1111/jpc.14863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Yes, there is a place for bariatric surgery (and paediatric surgeons) in childhood obesity.

    Jones, Niall

    Archives of disease in childhood

    2008  Volume 93, Issue 4, Page(s) 354

    MeSH term(s) Adolescent ; Adolescent Health Services/organization & administration ; Bariatric Surgery ; Child ; Humans ; London ; Obesity/surgery ; Patient Selection
    Language English
    Publishing date 2008-04
    Publishing country England
    Document type Letter
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Silk glove or just a pig's ear?

    Malakounides, Georgina / Jones, Niall

    Clinical pediatrics

    2014  Volume 53, Issue 9, Page(s) 896–897

    MeSH term(s) Child ; Child, Preschool ; Female ; Hernia, Inguinal/diagnosis ; Hernia, Inguinal/surgery ; Herniorrhaphy/methods ; Humans ; Infant ; Laparoscopy ; Male ; Sensitivity and Specificity
    Language English
    Publishing date 2014-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/0009922813499069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Re: Institutional review of patients presenting with suspected appendicitis.

    Tasker, Kate / Visa, Arjun / Jones, Niall

    ANZ journal of surgery

    2016  Volume 86, Issue 1-2, Page(s) 105

    MeSH term(s) Appendectomy ; Appendicitis/diagnosis ; Female ; Humans ; Male
    Language English
    Publishing date 2016-01
    Publishing country Australia
    Document type Comment ; Letter
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.13341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Antimalarial drugs alone may still have a role in rheumatoid arthritis.

    Cusnir, Ina / Dobing, Selina / Jones, Niall / Russell, Anthony

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

    2015  Volume 21, Issue 4, Page(s) 193–195

    Abstract: Objectives: Antimalarials have been used for the treatment of rheumatoid arthritis (RA) for several decades. Current guidelines do not include the use of these drugs alone for RA patients. The purpose of the study is to review RA patients, to find those ...

    Abstract Objectives: Antimalarials have been used for the treatment of rheumatoid arthritis (RA) for several decades. Current guidelines do not include the use of these drugs alone for RA patients. The purpose of the study is to review RA patients, to find those who have done well on antimalarials alone, and see if there are common features that predict good treatment outcome with these drugs.
    Methods: This is a retrospective chart review of patients who have been successfully treated with antimalarials alone. Patients who were attending routine follow-up and were seemingly in remission defined by no swollen or tender joints were selected over a 6-month period. Those who had being doing well but were now or had been on other agents were not included. The background data were reviewed to see if there were any common initial characteristics.
    Results: Thirty-three patients were seen who had been administered antimalarials alone and where initial data were available. Patients remain in clinical remission. Based on clinical observation, inflammatory markers, and radiographic reports, in the follow-up visits, they remain with no signs of inflammation and no new erosions on radiograph. Initial bone erosions on 2 patients remain stable over the years.
    Conclusions: There are some patients with confirmed RA who without doubt respond well to antimalarials alone. It is hard to objectively measure whether mild disease activity, early treatment initiation, lack of smoking, or other factors are contributing to a good treatment response.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Antimalarials/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Chloroquine/therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Antimalarials ; Chloroquine (886U3H6UFF)
    Language English
    Publishing date 2015-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1283266-2
    ISSN 1536-7355 ; 1076-1608
    ISSN (online) 1536-7355
    ISSN 1076-1608
    DOI 10.1097/RHU.0000000000000243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Using an optical trocar for laparoscopic access in overweight and obese children.

    Livesey, Emily / Jones, Niall

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2010  Volume 20, Issue 2, Page(s) 205–206

    Abstract: The open Hasson technique with a purse-string suture is generally favored among pediatric surgeons performing laparoscopy. This is a challenge in overweight and obese children and often leads to delays or conversion to laparotomy. In this article, we ... ...

    Abstract The open Hasson technique with a purse-string suture is generally favored among pediatric surgeons performing laparoscopy. This is a challenge in overweight and obese children and often leads to delays or conversion to laparotomy. In this article, we report our experience with an optical trocar for primary port access in overweight and obese children.
    MeSH term(s) Adolescent ; Appendicitis/surgery ; Child ; Cholecystectomy, Laparoscopic ; Colectomy/methods ; Female ; Fundoplication/methods ; Humans ; Laparoscopes ; Laparoscopy/methods ; Male ; Obesity/complications ; Overweight/complications ; Suture Techniques
    Language English
    Publishing date 2010-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2608063-1
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2009.0058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Experience with tofacitinib in Canada: patient characteristics and treatment patterns in rheumatoid arthritis over 3 years.

    Pope, Janet / Bessette, Louis / Jones, Niall / Fallon, Lara / Woolcott, John / Gruben, David / Crooks, Michael / Gold, David / Haraoui, Boulos

    Rheumatology (Oxford, England)

    2019  Volume 59, Issue 3, Page(s) 568–574

    Abstract: Objectives: To describe characteristics, treatment patterns and persistence in patients with RA treated with tofacitinib, an oral Janus kinase inhibitor, in Canadian clinical practice between 1 June 2014 and 31 May 2017.: Methods: Data were obtained ... ...

    Abstract Objectives: To describe characteristics, treatment patterns and persistence in patients with RA treated with tofacitinib, an oral Janus kinase inhibitor, in Canadian clinical practice between 1 June 2014 and 31 May 2017.
    Methods: Data were obtained from the tofacitinib eXel support programme. Baseline demographics and medication history were collected via patient report/special authorization forms; reasons for discontinuation were captured by patient report. Treatment persistence was estimated using Kaplan-Meier methods, with data censored at last follow-up. Cox regression was applied to analyse baseline characteristics associated with treatment discontinuation.
    Results: The number of patients with RA enrolled from 2014 to 2017 was 4276; tofacitinib utilization increased during that period, as did the proportion of biologic (b) DMARD-naïve patients prescribed tofacitinib. Of patients who initiated tofacitinib, 1226/3678 (33.3%) discontinued, mostly from lack of efficacy (35.7%) and adverse events (26.9%). Persistence was 62.7% and 49.6% after 1 and 2 years of treatment, respectively. Prior bDMARD experience predicted increased tofacitinib discontinuation (vs bDMARD-naïve, P < 0.001). Increased retention was associated with older age (56-65 years and >65 years vs ⩽45 years; P < 0.05), and time since diagnosis of 15 to <20 years (vs <5 years; P < 0.01). In bDMARD-naïve, post-1 bDMARD, post-2 bDMARD and post-⩾3 bDMARD patients, median survival was >730, 613, 667 and 592 days, respectively.
    Conclusion: Since 2014, tofacitinib use in Canadian patients with RA increased, especially among bDMARD-naïve/post-1 bDMARD patients. Median drug survival was ∼2 years. Likelihood of persistence increased for bDMARD-naïve (vs bDMARD-experienced) patients and those aged ⩾56 (vs ⩽45) years.
    MeSH term(s) Adult ; Age Factors ; Aged ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Canada ; Databases, Factual ; Female ; Humans ; Male ; Middle Aged ; Piperidines/therapeutic use ; Practice Patterns, Physicians' ; Pyrimidines/therapeutic use ; Pyrroles/therapeutic use ; Treatment Outcome
    Chemical Substances Antirheumatic Agents ; Piperidines ; Pyrimidines ; Pyrroles ; tofacitinib (87LA6FU830)
    Language English
    Publishing date 2019-08-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/kez324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Left Amyand's hernia in children: method, management and myth.

    Holmes, Matthew / Ee, Michael / Fenton, Edmond / Jones, Niall

    Journal of paediatrics and child health

    2013  Volume 49, Issue 9, Page(s) 789–790

    MeSH term(s) Appendix/pathology ; Hernia, Inguinal/diagnosis ; Hernia, Inguinal/surgery ; Herniorrhaphy ; Humans ; Infant ; Male
    Language English
    Publishing date 2013-09
    Publishing country Australia
    Document type Case Reports ; Letter
    ZDB-ID 1024476-1
    ISSN 1440-1754 ; 1034-4810
    ISSN (online) 1440-1754
    ISSN 1034-4810
    DOI 10.1111/jpc.12377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Retroperitoneal teratomas--potential for surgical misadventure.

    Jones, Niall M / Kiely, Edward M

    Journal of pediatric surgery

    2008  Volume 43, Issue 1, Page(s) 184–6; discussion 187

    Abstract: Background: Retroperitoneal teratoma (RPT) is a relatively uncommon tumor in children. This study concerns 6 children with RPT that involved surrounding structures and required rather extensive operative procedures to successfully excise the lesions.: ...

    Abstract Background: Retroperitoneal teratoma (RPT) is a relatively uncommon tumor in children. This study concerns 6 children with RPT that involved surrounding structures and required rather extensive operative procedures to successfully excise the lesions.
    Methods: A review of RPT in children encountered at a single institution over an 8-year period by a single surgeon was carried out. Age at presentation, sex, operative findings, surgical management, and outcomes were evaluated.
    Results: Four of the 6 patients were girls, and 5 were younger than 6 months at diagnosis. All of the tumors enveloped and displaced the aorta and vena cava, 1 involved the stomach wall, 2 others displaced the renal vessels, and 1 the portal vein. Extensive resection including major vessel ligation was necessary for complete excision. All the tumors were benign, but 1 recurred. There were no deaths; however, 2 children have persistent hypertension.
    Conclusions: The operative management of RPTs may be complex and challenging. Despite their benign nature, the lesions can attenuate and surround major vessels, making resection difficult. Ligation of major vessels when necessary is tolerated well and may be required for complete tumor excision.
    MeSH term(s) Biopsy, Needle ; Child ; Female ; Follow-Up Studies ; Humans ; Immunohistochemistry ; Infant ; Infant, Newborn ; Laparotomy/methods ; Male ; Neoplasm Invasiveness/pathology ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Retroperitoneal Neoplasms/pathology ; Retroperitoneal Neoplasms/surgery ; Retrospective Studies ; Risk Assessment ; Teratoma/pathology ; Teratoma/surgery ; Treatment Outcome ; United Kingdom ; Vena Cava, Inferior/pathology ; Vena Cava, Inferior/surgery
    Language English
    Publishing date 2008-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2007.09.041
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