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  1. Article: Fructooligosaccharides (FOS) differentially modifies the

    Mahalak, Karley K / Firrman, Jenni / Narrowe, Adrienne B / Hu, Weiming / Jones, Steven M / Bittinger, Kyle / Moustafa, Ahmed M / Liu, LinShu

    Frontiers in nutrition

    2023  Volume 9, Page(s) 1058910

    Abstract: Introduction: Fructooligosaccharides (FOS) are well-known carbohydrates that promote healthy gut microbiota and have been previously demonstrated to enhance levels of : Methods: To address this concern, we implemented a 24-h : Results: These ... ...

    Abstract Introduction: Fructooligosaccharides (FOS) are well-known carbohydrates that promote healthy gut microbiota and have been previously demonstrated to enhance levels of
    Methods: To address this concern, we implemented a 24-h
    Results: These analyses found that FOS created a bifidogenic response in all age groups, increased overall SCFA levels, decreased alpha diversity, and shifted the communities to be more similar in beta diversity metrics. However, the age groups differed in which taxa were most prevalent or most affected by FOS treatment.
    Discussion: Overall, the results of this study demonstrate the positive effects of FOS on the gut microbiome, and importantly, how age may play a role in the effectiveness of this prebiotic.
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.1058910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: An

    Firrman, Jenni / Liu, LinShu / Mahalak, Karley / Hu, Weiming / Bittinger, Kyle / Moustafa, Ahmed / Jones, Steven M / Narrowe, Adrienne / Tomasula, Peggy

    Frontiers in nutrition

    2023  Volume 9, Page(s) 1040744

    Abstract: Introduction: Following consumption of milk, lactose, a disaccharide of glucose and galactose, is hydrolyzed and absorbed in the upper gastrointestinal tract. However, hydrolysis and absorption are not always absolute, and some lactose will enter the ... ...

    Abstract Introduction: Following consumption of milk, lactose, a disaccharide of glucose and galactose, is hydrolyzed and absorbed in the upper gastrointestinal tract. However, hydrolysis and absorption are not always absolute, and some lactose will enter the colon where the gut microbiota is able to hydrolyze lactose and produce metabolic byproducts.
    Methods: Here, the impact of lactose on the gut microbiota of healthy adults was examined, using a short-term,
    Results and discussion: Metagenomic sequencing found that the addition of lactose decreased richness and evenness, while enhancing prevalence of the β-galactosidase gene. Taxonomically, lactose treatment decreased relative abundance of
    Language English
    Publishing date 2023-01-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.1040744
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The story of Canada's Ebola vaccine.

    Plummer, Francis A / Jones, Steven M

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2017  Volume 189, Issue 43, Page(s) E1326–E1327

    MeSH term(s) Canada ; Ebola Vaccines ; Hemorrhagic Fever, Ebola ; Humans
    Chemical Substances Ebola Vaccines
    Language English
    Publishing date 2017-10-30
    Publishing country Canada
    Document type Journal Article ; Comment
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.170704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.136: Show issues Location:
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  4. Article ; Online: Avulsion of the Distal Sealing Stent of a Zenith Aortouni-iliac Stent-Graft.

    Jones, Steven M / Torella, Francesco

    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists

    2016  Volume 23, Issue 5, Page(s) 821–823

    Abstract: Purpose: To describe a life-threatening complication during endovascular aneurysm repair that was caused by a series of errors.: Case report: A 64-year-old man received a Zenith aortouni-iliac stent-graft for a 61-mm saccular aortic aneurysm. During ... ...

    Abstract Purpose: To describe a life-threatening complication during endovascular aneurysm repair that was caused by a series of errors.
    Case report: A 64-year-old man received a Zenith aortouni-iliac stent-graft for a 61-mm saccular aortic aneurysm. During retrieval of the delivery system, the sheath became dislodged from the common femoral artery. Reintroduction caused the top cap to disengage from the pusher rod because the pin vice had not been tightened as per the instructions for use. Subsequent traction was applied but the delivery system could not be withdrawn from the sheath, thus it was decided to remove the delivery system and sheath en masse. On removal, the distal sealing stent was found deformed and wedged between the top cap and the sheath. Perforation of the common iliac artery by the avulsed stent was treated with iliac limb extension before contralateral iliac plug and femorofemoral bypass graft were performed as planned. The patient made an uneventful recovery.
    Conclusion: Trapping of the distal sealing stent between the top cap and the pusher rod of the Zenith graft is possible and can be prevented by securing the pin vice prior to retrieval. Description of this complication may prevent similar occurrences in future.
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006618-1
    ISSN 1545-1550 ; 1526-6028
    ISSN (online) 1545-1550
    ISSN 1526-6028
    DOI 10.1177/1526602816655308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4547: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Book: Tattooing of cattle and goats

    Jones, Steven M

    (FSA ; 4015 ; Agriculture and natural resources)

    2014  

    Institution University of Arkansas (System). / Cooperative Extension Service
    Author's details Steven M. Jones
    Series title FSA ; 4015
    Agriculture and natural resources
    Keywords Tattooing. ; Cattle/Marking. ; Goats/Marking. ; Livestock brands.
    Language English
    Size [4] pages :, illustrations;, 28 cm.
    Publisher Cooperative Extension Service, University of Arkansas Division of Agriculture, U.S. Dept. of Agriculture, and county governments cooperating
    Publishing place Little Rock, Ark.
    Document type Book
    Note "FSA4015-PD-3-2014RV" -- P. [4]. ; Not distributed; available at Arkansas State Library.
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Atrazine Removal from Municipal Wastewater Using a Membrane Bioreactor.

    Kamaz, Mohanad / Jones, Steven M / Qian, Xianghong / Watts, Michael J / Zhang, Wen / Wickramasinghe, S Ranil

    International journal of environmental research and public health

    2020  Volume 17, Issue 7

    Abstract: As the demand for potable water increases, direct potable reuse of wastewater is an attractive alternative method to produce potable water. However, implementation of such a process will require the removal of emerging contaminants which could accumulate ...

    Abstract As the demand for potable water increases, direct potable reuse of wastewater is an attractive alternative method to produce potable water. However, implementation of such a process will require the removal of emerging contaminants which could accumulate in the drinking water supply. Here, the removal of atrazine, a commonly used herbicide, has been investigated. Using real and synthetic wastewater, as well as sludge from two wastewater treatment facilities in the United States in Norman, Oklahoma and Fayetteville, Arkansas, atrazine removal has been investigated. Our results indicate that about 20% of the atrazine is removed by adsorption onto the particulate matter present. Significant biodegradation of atrazine was only observed under aerobic conditions for sludge from Norman, Oklahoma. Next-generation sequencing of the activated sludge revealed the abundance of
    MeSH term(s) Arkansas ; Atrazine ; Biodegradation, Environmental ; Bioreactors ; Oklahoma ; Sewage ; Waste Disposal, Fluid ; Waste Water ; Water Pollutants, Chemical ; Water Purification
    Chemical Substances Sewage ; Waste Water ; Water Pollutants, Chemical ; Atrazine (QJA9M5H4IM)
    Language English
    Publishing date 2020-04-09
    Publishing country Switzerland
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17072567
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  7. Article: A Nanofiltration Decision Tool for Potable Reuse: A New Rejection Model for Recalcitrant CECs.

    Jones, Steven M / Watts, Michael J / Wickramasinghe, S Ranil

    Water environment research : a research publication of the Water Environment Federation

    2017  Volume 89, Issue 11, Page(s) 1942–1951

    Abstract: Effluent samples from three water resource recovery facilities (WRRFs) were individually characterized for presence and concentration of 94 different chemicals of emerging concern (CECs), using analytical methods with reporting limits in the low-parts- ... ...

    Abstract Effluent samples from three water resource recovery facilities (WRRFs) were individually characterized for presence and concentration of 94 different chemicals of emerging concern (CECs), using analytical methods with reporting limits in the low-parts-per-trillion. Following CEC analysis, each sample was subjected to dead-end, pressurized membrane filtration with either a nanofiltration (NF) or reverse osmosis (RO) membrane. The majority of the measured CECs were rejected by both membranes by 1-log removal (90%) or greater. However, nine of the 94 CECs had average rejection rates by the NF membrane less than 90%. A multilevel, multivariable model was developed to predict the probable rejection coefficients of CECs with the studied NF membrane. The resulting Quantitative Molecular Properties Model (QMPM) predicted the NF rejection of CECs based on size, ionic charge, and hydrophobicity. The model parameters that successfully predicted NF rejection in bench testing were log (Kow/Kaw) and the polar surface area of the CEC molecule.
    Language English
    Publishing date 2017-11-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1098976-6
    ISSN 1554-7531 ; 1061-4303 ; 1047-7624
    ISSN (online) 1554-7531
    ISSN 1061-4303 ; 1047-7624
    DOI 10.2175/106143017X14902968254629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 490: Show issues Location:
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  8. Article ; Online: Impact of Ivermectin on the Gut Microbial Ecosystem.

    Liu, LinShu / Mahalak, Karley K / Bobokalonov, Jamshed T / Narrowe, Adrienne B / Firrman, Jenni / Lemons, Johanna M S / Bittinger, Kyle / Hu, Weiming / Jones, Steven M / Moustafa, Ahmed M

    International journal of molecular sciences

    2023  Volume 24, Issue 22

    Abstract: Ivermectin is a an anti-helminthic that is critical globally for both human and veterinary care. To the best of our knowledge, information available regarding the influence of ivermectin (IVM) on the gut microbiota has only been collected from diseased ... ...

    Abstract Ivermectin is a an anti-helminthic that is critical globally for both human and veterinary care. To the best of our knowledge, information available regarding the influence of ivermectin (IVM) on the gut microbiota has only been collected from diseased donors, who were treated with IVM alone or in combination with other medicines. Results thus obtained were influenced by multiple elements beyond IVM, such as disease, and other medical treatments. The research presented here investigated the impact of IVM on the gut microbial structure established in a Triple-SHIME
    MeSH term(s) Adult ; Humans ; Feces ; Gastrointestinal Microbiome/genetics ; Ivermectin/pharmacology ; RNA, Ribosomal, 16S/genetics
    Chemical Substances Ivermectin (70288-86-7) ; RNA, Ribosomal, 16S
    Language English
    Publishing date 2023-11-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242216125
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  9. Article ; Online: A taxonomy of chemicals of emerging concern based on observed fate at water resource recovery facilities.

    Jones, Steven M / Chowdhury, Zaid K / Watts, Michael J

    Chemosphere

    2017  Volume 170, Page(s) 153–160

    Abstract: As reuse of municipal water resource recovery facility (WRRF) effluent becomes vital to augment diminishing fresh drinking water resources, concern exists that conventional barriers may prove deficient, and the upcycling of chemicals of emerging concern ( ...

    Abstract As reuse of municipal water resource recovery facility (WRRF) effluent becomes vital to augment diminishing fresh drinking water resources, concern exists that conventional barriers may prove deficient, and the upcycling of chemicals of emerging concern (CECs) could prove harmful to human health and aquatic species if more effective and robust treatment barriers are not in place. A multiple month survey, of both primary and secondary effluents, from three (3) WRRFs, for 95 CECs was conducted in 2014 to classify CECs by their persistence through conventional water reclamation processes. By sampling the participating WRRF process trains at their peak performance (as determined by measured bulk organics and particulates removal), a short-list of recalcitrant CECs that warrant monitoring to assess treatment performance at advanced water reclamation and production facilities. The list of identified CECs for potable water reclamation (indirect or direct potable reuse) include a herbicide and its degradants, prescription pharmaceuticals and antibiotics, a female hormone, an artificial sweetener, and chlorinated flame retardants.
    MeSH term(s) Anti-Bacterial Agents/analysis ; Cities ; Drinking Water ; Environmental Monitoring/methods ; Flame Retardants/analysis ; Herbicides/analysis ; Hormones/analysis ; Humans ; Oklahoma ; Pharmaceutical Preparations/analysis ; Sewage ; Sweetening Agents/analysis ; Texas ; Water Pollutants, Chemical/analysis ; Water Purification/methods ; Water Resources
    Chemical Substances Anti-Bacterial Agents ; Drinking Water ; Flame Retardants ; Herbicides ; Hormones ; Pharmaceutical Preparations ; Sewage ; Sweetening Agents ; Water Pollutants, Chemical
    Language English
    Publishing date 2017-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2016.11.075
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
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  10. Article ; Online: Activities of JNJ63623872 and oseltamivir against influenza A H1N1pdm and H3N2 virus infections in mice.

    Smee, Donald F / Barnard, Dale L / Jones, Steven M

    Antiviral research

    2016  Volume 136, Page(s) 45–50

    Abstract: JNJ63623872 (formerly known as VX-787) is an inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit. This interaction blocks the cap-snatching activity of the virus that is essential for virus replication. Previously ... ...

    Abstract JNJ63623872 (formerly known as VX-787) is an inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit. This interaction blocks the cap-snatching activity of the virus that is essential for virus replication. Previously published work has documented antiviral activity of JNJ63623872 in cell culture and mouse infection studies. In this report, we extend the in vivo observations by comparing the efficacies of JNJ63623872 and oseltamivir in mice infected with influenza A/California/04/2009 (H1N1pdm) and A/Victoria/3/75 (H3N2) viruses. Animals received JNJ63623872 or oseltamivir orally twice daily for 10 days starting 2 h pre-infection. JNJ63623872 (2, 6, and 20 mg/kg/day) and oseltamivir (20 mg/kg/day) completely prevented death in the H1N1pdm virus infection. Weight loss at nadir was only 12% in mice receiving 2 mg/kg/day of JNJ63623872 compared to 23% and 32%, respectively, in oseltamivir-treated (20 mg/kg/day) and placebo groups. Lung hemorrhage scores, lung weights, and lung virus titers on day 6 were reduced in a dose-responsive manner by JNJ63623872 treatments, whereas oseltamivir treatments were not as effective. JNJ63623872 was less active against H3N2 virus infection, with more body weight loss occurring and only 30% survival at the 2-mg/kg/day dose. Lung scores, lung weights, and H3N2 viral titers in lungs of mice were reduced less by JNJ63623872 treatments compared to the H1N1pdm infection. Nevertheless, the 20-mg/kg/day dose of JNJ63623872 was more effective than oseltamivir (20 mg/kg/day) in improving body weight and reducing the severity of lung infection. JNJ63623872 appears to be an important new drug candidate to treat influenza A H1N1pdm and H3N2 virus infections.
    MeSH term(s) Animals ; Antiviral Agents/therapeutic use ; Drug Discovery ; Drug Therapy, Combination ; Indoles/administration & dosage ; Indoles/therapeutic use ; Influenza A Virus, H1N1 Subtype/drug effects ; Influenza A Virus, H3N2 Subtype/drug effects ; Lung/virology ; Mice ; Orthomyxoviridae Infections/drug therapy ; Orthomyxoviridae Infections/virology ; Oseltamivir/administration & dosage ; Oseltamivir/therapeutic use ; Viral Load/drug effects ; Virus Replication/drug effects
    Chemical Substances Antiviral Agents ; Indoles ; Oseltamivir (20O93L6F9H) ; pimodivir (DFC121MXC3)
    Language English
    Publishing date 2016-10-19
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 306628-9
    ISSN 1872-9096 ; 0166-3542
    ISSN (online) 1872-9096
    ISSN 0166-3542
    DOI 10.1016/j.antiviral.2016.10.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1627: Show issues Location:
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