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Article ; Online: Missing Stories: Women with Physical Disabilities' Navigation and Responses to Domestic and Family Violence.

Jordan, Karen

2022 Volume 28, Issue 15-16, Page(s) 3681–3702

Abstract: There is significant global evidence that highlights both the high rates of domestic and family violence (DFV) for women with disabilities and the challenges they can face when navigating and responding to DFV. The purpose of this study was to understand ...

Abstract	There is significant global evidence that highlights both the high rates of domestic and family violence (DFV) for women with disabilities and the challenges they can face when navigating and responding to DFV. The purpose of this study was to understand women with physical disabilities' experiences of help-seeking when they did not access generalist DFV services. Presented are the participants' lived experiences of navigating and responding to DFV. Key findings include how participants resisted ableism, challenged assumptions about passivity, and the impacts of this resistance on their navigation of DFV.
MeSH term(s)	Female ; Humans ; Domestic Violence ; Disabled Persons
Language	English
Publishing date	2022-02-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2031375-5
ISSN	1552-8448 ; 1077-8012
ISSN (online)	1552-8448
ISSN	1077-8012
DOI	10.1177/10778012221079377
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Article ; Online: Animated teaching improves student learning of human gastrulation and neurulation.

O'Connor, Cole / Jordan, Karen / Vagg, Tamara / Murphy, Carrie E / Barry, Denis S / Toulouse, André / Fletcher, Jean M / Downer, Eric J

Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft

2023 Volume 247, Page(s) 152057

Abstract: Human embryology is a complex topic that brings together core components of anatomy and physiology to describe the developmental process from fertilisation to birth. Embryonic development is a challenging topic of study that is core to the curricula for ... ...

Abstract	Human embryology is a complex topic that brings together core components of anatomy and physiology to describe the developmental process from fertilisation to birth. Embryonic development is a challenging topic of study that is core to the curricula for health science students. There are challenges ingrained in teaching and learning embryology, due to the three-dimensional dynamic processes that occur as the embryo develops. This study aimed to develop and assess two newly developed animations depicting key processes in embryology, namely gastrulation and neurulation, as supplemental learning aids for students. Indeed, animated teaching tools to enhance the learning of gastrulation and neurulation are not widely available. A multi-disciplinary team of physiologists, biochemists, anatomists, and a computer scientist developed the animation sets. A student cohort of 81 first-year health science students were enrolled in this study over a period of three academic years. Both animations are in line with the course content of the first-year health science students undertaking the Human Health and Disease BSc at Trinity College Dublin, who were the study participants. Participants were randomly assigned to a non-animation control group and an animation group. Each set of animated teaching aids was broken down into individual clips which were given identifiable headings to allow the user to interchange between clips to facilitate a more personal learning experience. The animation group had open access to the animations for a three-week period. Questionnaires were designed to assess participants' attitude to the animations and their knowledge of embryology, both at the start of the study and three weeks later following access to the animations. Data presented herein indicate that students incorporated the animated teaching aids into digital home study and that the use of the animations acted as a supplemental tool that increased student knowledge in key areas of human embryology. From a qualitative point of view, students described the animations as enjoyable and helpful in visualising complex processes. This study indicates that the development of gastrulation and neurulation animated learning tools allow for a more engaging learning experience, facilitating student's engagement with academically challenging concepts in human embryology.
MeSH term(s)	Humans ; Computer-Assisted Instruction ; Neurulation ; Gastrulation ; Students ; Learning ; Teaching
Language	English
Publishing date	2023-01-23
Publishing country	Germany
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1106738-x
ISSN	1618-0402 ; 0940-9602
ISSN (online)	1618-0402
ISSN	0940-9602
DOI	10.1016/j.aanat.2023.152057
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Article ; Online: Prehospital Resuscitation Decisions in Cases of Traumatic Cardiopulmonary Arrest: Assessing the Risk of Legal Liability & the Impact of TOR Guidelines.

Jordan, Karen A / Fallat, Mary E

The Journal of legal medicine

2015 Volume 36, Issue 2, Page(s) 159–213

MeSH term(s)	Cardiopulmonary Resuscitation ; Emergency Medical Services ; Humans ; Liability, Legal ; Out-of-Hospital Cardiac Arrest/therapy ; Practice Guidelines as Topic ; United States ; Withholding Treatment/legislation & jurisprudence
Language	English
Publishing date	2015-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	604915-1
ISSN	1521-057X ; 0194-7648
ISSN (online)	1521-057X
ISSN	0194-7648
DOI	10.1080/01947648.2015.1121073
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Article ; Online: Cost-effectiveness of metabolic surgery for the treatment of type 2 diabetes and obesity: a systematic review of economic evaluations.

Jordan, Karen / Fawsitt, Christopher G / Carty, Paul G / Clyne, Barbara / Teljeur, Conor / Harrington, Patricia / Ryan, Mairin

The European journal of health economics : HEPAC : health economics in prevention and care

2022 Volume 24, Issue 4, Page(s) 575–590

Abstract: Aim: To systematically identify and appraise the international literature on the cost-effectiveness of metabolic surgery for the treatment of comorbid type 2 diabetes (T2D) and obesity.: Methods: A systematic search was conducted in electronic ... ...

Abstract	Aim: To systematically identify and appraise the international literature on the cost-effectiveness of metabolic surgery for the treatment of comorbid type 2 diabetes (T2D) and obesity. Methods: A systematic search was conducted in electronic databases and grey literature sources up to 20 January 2021. Economic evaluations in a T2D population or a subpopulation with T2D were eligible for inclusion. Screening, data extraction, critical appraisal of methodological quality (Consensus Health Economic Criteria list) and assessment of transferability (International Society for Pharmacoeconomics and Outcomes Research questionnaire) were undertaken in duplicate. The incremental cost-effectiveness ratio (ICER) was the main outcome. Costs were reported in 2020 Irish Euro. Cost-effectiveness was interpreted using willingness-to-pay (WTP) thresholds of €20,000 and €45,000/quality-adjusted life year (QALY). Due to heterogeneity arising from various sources, a narrative synthesis was undertaken. Results: Thirty studies across seventeen jurisdictions met the inclusion criteria; 16 specifically in a T2D population and 14 in a subpopulation with T2D. Overall, metabolic surgery was found to be cost-effective or cost-saving. Where undertaken, the results were robust to sensitivity and scenario analyses. Of the 30 studies included, 15 were considered high quality. Identified limitations included limited long-term follow-up data and uncertainty regarding the utility associated with T2D remission. Conclusion: Published high-quality studies suggest metabolic surgery is a cost-effective or cost-saving intervention. As the prevalence of obesity and obesity-related diseases increases worldwide, significant investment and careful consideration of the resource requirements needed for metabolic surgery programmes will be necessary to ensure that service provision is adequate to meet demand.
MeSH term(s)	Humans ; Cost-Benefit Analysis ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/surgery ; Obesity/epidemiology ; Obesity/surgery ; Bariatric Surgery ; Outcome Assessment, Health Care
Language	English
Publishing date	2022-07-22
Publishing country	Germany
Document type	Systematic Review ; Journal Article
ZDB-ID	2045253-6
ISSN	1618-7601 ; 1618-7598
ISSN (online)	1618-7601
ISSN	1618-7598
DOI	10.1007/s10198-022-01494-2
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Article ; Online: Challenges encountered during the systematic review of newer and enhanced influenza vaccines and recommendations for the future.

Teljeur, Conor / Comber, Laura / Jordan, Karen / Murchu, Eamon O / Harrington, Patricia / O'Neill, Michelle / Ryan, Máirín

Reviews in medical virology

2022 Volume 32, Issue 5, Page(s) e2335

Abstract: There are a variety of challenges in the conduct of systematic reviews of influenza vaccines. We describe our experience of completing four systematic reviews of newer and enhanced inactivated seasonal influenza vaccines. The reporting of the included ... ...

Abstract	There are a variety of challenges in the conduct of systematic reviews of influenza vaccines. We describe our experience of completing four systematic reviews of newer and enhanced inactivated seasonal influenza vaccines. The reporting of the included studies created significant challenges for study identification, data extraction and analysis. Those challenges have implications for the resources required to conduct reviews and, more significantly, for the accuracy of the estimated treatment effect. There is a substantial burden of morbidity and mortality associated with seasonal influenza, and the evidence used to support vaccination strategies requires regular review. An improved review process will facilitate robust decision-making both nationally and internationally. We recommend the development of reporting guidelines, increased engagement between researchers and decision makers, a database of identified trials, and research into search optimisation.
MeSH term(s)	Humans ; Influenza Vaccines ; Influenza, Human/prevention & control ; Systematic Reviews as Topic ; Vaccination ; Vaccines, Inactivated
Chemical Substances	Influenza Vaccines ; Vaccines, Inactivated
Language	English
Publishing date	2022-02-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1086043-5
ISSN	1099-1654 ; 1052-9276
ISSN (online)	1099-1654
ISSN	1052-9276
DOI	10.1002/rmv.2335
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Article: The final chapter (maybe) of preemption of HMO accountability under state law.

Jordan, Karen

Health care law monthly

2004 , Page(s) 15–27

MeSH term(s)	Employee Retirement Income Security Act/legislation & jurisprudence ; Health Maintenance Organizations/economics ; Health Maintenance Organizations/legislation & jurisprudence ; Humans ; Insurance Claim Review/legislation & jurisprudence ; Liability, Legal ; Malpractice/legislation & jurisprudence ; Social Responsibility ; Supreme Court Decisions ; United States
Language	English
Publishing date	2004-02
Publishing country	United States
Document type	Journal Article ; Legal Cases
ISSN	1526-0704
ISSN	1526-0704
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Article ; Online: A cost-effectiveness and budget impact analysis of C-reactive protein point-of-care testing to guide antibiotic prescribing for acute respiratory tract infections in primary care settings in Ireland: a decision-analytic model.

Fawsitt, Christopher G / Lucey, Des / Harrington, Patricia / Jordan, Karen / Marshall, Liam / O'Brien, Kirsty K / Teljeur, Conor

Family practice

2021 Volume 39, Issue 3, Page(s) 389–397

Abstract: Background: Approximately 60% of antibiotics issued in primary care are for acute respiratory tract infections (RTIs), which are largely self-limiting and do not require antibiotics. Point-of-care testing (POCT) devices that measure C-reactive protein ( ... ...

Abstract	Background: Approximately 60% of antibiotics issued in primary care are for acute respiratory tract infections (RTIs), which are largely self-limiting and do not require antibiotics. Point-of-care testing (POCT) devices that measure C-reactive protein (CRP)-a biomarker for infection-can be used to guide prescribing decisions. Objective: We evaluated the cost-effectiveness and budget impact of a national CRP POCT program to guide antibiotic prescribing for acute RTIs in primary care in Ireland. Methods: We compared CRP POCT with and without enhanced communication skills training of general practitioners against usual care. A probabilistic decision tree was used to investigate cost-effectiveness from the perspective of the healthcare system. The model considered outcomes for the Irish population over a 5-year time horizon. Inputs were synthesized from published studies. Cost-effectiveness was estimated using an incremental cost per prescription avoided. Results: CRP POCT with and without communication training were more costly but more effective than usual care over 5 years. CRP POCT alone was dominated, while the combined intervention had a cost per prescription avoided of €111 (95% CI: €45-243) versus usual care. The budget impact was costly over 5 years, but potential budget savings were available depending on the implementation scenario. The findings were largely robust to sensitivity analyses. Conclusions: CRP POCT reduces antibiotic prescribing, but increases healthcare costs. The most cost-effective program of CRP POCT includes enhanced communication skills training. Further research on the impact of CRP POCT beyond 5 years is warranted, as well as the potential impact on antimicrobial resistance.
MeSH term(s)	Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/economics ; C-Reactive Protein/analysis ; Cost-Benefit Analysis ; Humans ; Ireland ; Point-of-Care Testing ; Primary Health Care ; Respiratory Tract Infections/diagnosis ; Respiratory Tract Infections/drug therapy
Chemical Substances	Anti-Bacterial Agents ; C-Reactive Protein (9007-41-4)
Language	English
Publishing date	2021-09-29
Publishing country	England
Document type	Journal Article
ZDB-ID	605939-9
ISSN	1460-2229 ; 0263-2136
ISSN (online)	1460-2229
ISSN	0263-2136
DOI	10.1093/fampra/cmab123
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Article ; Online: Transmission of SARS-CoV-2 by children: a rapid review, 30 December 2019 to 10 August 2020.

Clyne, Barbara / Jordan, Karen / Ahern, Susan / Walsh, Kieran A / Byrne, Paula / Carty, Paul G / Drummond, Linda / O'Brien, Kirsty K / Smith, Susan M / Harrington, Patricia / Ryan, Máirín / O'Neill, Michelle

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

2022 Volume 27, Issue 5

Abstract: BackgroundThe role of children in the transmission of SARS-CoV-2 during the early pandemic was unclear.AimWe aimed to review studies on the transmission of SARS-CoV-2 by children during the early pandemic.MethodsWe searched MEDLINE, Embase, the Cochrane ... ...

Abstract	BackgroundThe role of children in the transmission of SARS-CoV-2 during the early pandemic was unclear.AimWe aimed to review studies on the transmission of SARS-CoV-2 by children during the early pandemic.MethodsWe searched MEDLINE, Embase, the Cochrane Library, Europe PubMed Central and the preprint servers medRxiv and bioRxiv from 30 December 2019 to 10 August 2020. We assessed the quality of included studies using a series of questions adapted from related tools. We provide a narrative synthesis of the results.ResultsWe identified 28 studies from 17 countries. Ten of 19 studies on household and close contact transmission reported low rates of child-to-adult or child-to-child transmission. Six studies investigated transmission of SARS-CoV-2 in educational settings, with three studies reporting 183 cases from 14,003 close contacts who may have contracted COVID-19 from children index cases at their schools. Three mathematical modelling studies estimated that children were less likely to infect others than adults. All studies were of low to moderate quality.ConclusionsDuring the early pandemic, it appeared that children were not substantially contributing to household transmission of SARS-CoV-2. School-based studies indicated that transmission rates in this setting were low. Large-scale studies of transmission chains using data collected from contact tracing and serological studies detecting past evidence of infection would be needed to verify our findings.
MeSH term(s)	COVID-19 ; Contact Tracing ; Humans ; Pandemics ; SARS-CoV-2 ; Schools
Language	English
Publishing date	2022-02-03
Publishing country	Sweden
Document type	Journal Article ; Review
ZDB-ID	1338803-4
ISSN	1560-7917 ; 1025-496X
ISSN (online)	1560-7917
ISSN	1025-496X
DOI	10.2807/1560-7917.ES.2022.27.5.2001651
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Article ; Online: ADAPTE with modified Delphi supported developing a National Clinical Guideline: stratification of clinical risk in pregnancy.

Clyne, Barbara / Tyner, Barrie / O'Neill, Michelle / Jordan, Karen / Carty, Paul G / Phillips, Mahdiye K / Power, Karen / Turner, Michael J / Smith, Susan M / Ryan, Mairin

Journal of clinical epidemiology

2022 Volume 147, Page(s) 21–31

Abstract: Objectives: Adaptation has been proposed as an alternative to de novo development to take advantage of existing clinical guidelines (guidelines) and reduce duplication. We describe the process of incorporating a modified Delphi method to reach formal ... ...

Abstract	Objectives: Adaptation has been proposed as an alternative to de novo development to take advantage of existing clinical guidelines (guidelines) and reduce duplication. We describe the process of incorporating a modified Delphi method to reach formal consensus and inform locally relevant clinical recommendations during the development, through the ADAPTE process, of the Irish National Clinical Guideline No. 23 Stratification of Clinical Risk in Pregnancy. Methods: A systematic search of guideline repositories, websites, and bibliographic databases was conducted. Quality appraisal was undertaken using AGREE II. Risk factors indicating the need for additional care were identified and extracted from high-quality guidelines. A three-round modified Delphi panel comprising healthcare stakeholders, was convened to agree and tailor risk factors. Results: Of seven relevant international guidelines identified, three were considered high quality and contained a combined 59 risk factors potentially suitable for adaptation. Following the three-round Delphi process, 49 risk factors were included in the final guideline. Excluded risk factors were generally considered to be too broad to be useful for the Irish context. Conclusion: We believe that a formal consensus technique included within the ADAPTE process increased the rigor and transparency of this process and ensured the inclusion of more locally relevant risk factors.
MeSH term(s)	Consensus ; Databases, Bibliographic ; Delphi Technique ; Female ; Humans ; Pregnancy
Language	English
Publishing date	2022-03-18
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639306-8
ISSN	1878-5921 ; 0895-4356
ISSN (online)	1878-5921
ISSN	0895-4356
DOI	10.1016/j.jclinepi.2022.03.005
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Article ; Online: The effectiveness of non-contact thermal screening as a means of identifying cases of Covid-19: a rapid review of the evidence.

Cardwell, Karen / Jordan, Karen / Byrne, Paula / Smith, Susan M / Harrington, Patricia / Ryan, Mairin / O'Neill, Michelle

Reviews in medical virology

2020 Volume 31, Issue 4, Page(s) e2192

Abstract: The aim of this rapid review is to summarise the evidence on non-contact thermal screening as a method through which to identify cases and reduce the spread of coronavirus disease (Covid-19). The rapid review was conducted in accordance with Cochrane ... ...

Abstract	The aim of this rapid review is to summarise the evidence on non-contact thermal screening as a method through which to identify cases and reduce the spread of coronavirus disease (Covid-19). The rapid review was conducted in accordance with Cochrane guidelines, with a systematic search of published peer-reviewed articles and non-peer-reviewed pre-prints undertaken from 1 January 2000 up to 7 October 2020. Eleven studies were included. One observational study and two mathematical modelling studies were conducted in the context of the Covid-19 pandemic; the remaining studies were conducted during the influenza A pandemic (H1N1) 2009 (n = 7) or middle east respiratory syndrome (n = 1) pandemics. One systematic review and three rapid reviews were identified and screened for relevant studies. Evidence on the effectiveness of thermal screening contained within this review was limited to points of entry (i.e., airports); thus the applicability to other community settings is uncertain. Thermal screening, implemented as part of a composite of screening measures (self-report of relevant symptoms, contact/travel history), was ineffective in identifying infectious individuals and limiting the spread of disease. Based on limited, low certainty evidence, non-contact thermal screening is ineffective in limiting the spread of Covid-19.
MeSH term(s)	COVID-19/diagnosis ; COVID-19/prevention & control ; COVID-19 Testing/methods ; Fever/diagnosis ; Humans ; Mass Screening/methods
Language	English
Publishing date	2020-11-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1086043-5
ISSN	1099-1654 ; 1052-9276
ISSN (online)	1099-1654
ISSN	1052-9276
DOI	10.1002/rmv.2192
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