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  1. AU="José P. Oliveira-Filho"
  2. AU="Munt, Jennifer E"
  3. AU="Whiley, Phillip J"
  4. AU="V.Sudhir, "
  5. AU="Chatow, Lior"
  6. AU=Xue Zhe
  7. AU="Peter D. Yurchenco"
  8. AU="Várbíró, Gábor"
  9. AU="Sheleg, Dmitriy"
  10. AU="Panzirer, David"

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  1. Artikel ; Online: Main diseases of cattle in the midwestern region of São Paulo state

    Cristiana R. Bromberger / João Pedro M. Oliveira / Ana Maria D. Costa / Rogério M. Amorim / Alexandre S. Borges / José P. Oliveira-Filho

    Pesquisa Veterinária Brasileira, Vol

    2023  Band 43

    Abstract: ABSTRACT: São Paulo state is one of the country’s largest producers of beef and milk, and the midwestern region plays a key role in this production, as half of São Paulo’s cattle herd is found in this region. These numbers alone demonstrate the ... ...

    Abstract ABSTRACT: São Paulo state is one of the country’s largest producers of beef and milk, and the midwestern region plays a key role in this production, as half of São Paulo’s cattle herd is found in this region. These numbers alone demonstrate the importance of livestock in this region. Therefore, this study aimed to describe the main epidemiological and clinical signs in cattle cases at the Large Animal Hospital at FMVZ-Unesp, located in the midwestern region of São Paulo state. The present retrospective study assessed 638 clinical cases of cattle treated from January 2010 to December 2019 (10 years). Digestive system diseases were the most prevalent, diagnosed in 30.3% of patients, followed by neurological diseases (19.1%) and respiratory diseases (10.5%). The other diseases were distributed in decreasing order as follows: musculoskeletal (7.8%), hematopoietic (6.1%), genitourinary (5.6%), metabolic and nutritional (5.5%), neonatal (4.7%), cutaneous (2.6%), poisoning (2.5%), lymphatic (2.2%), cardiovascular (1.6%) and other diseases (1.4%). Rabies, a fatal zoonotic disease, was the main cause of death in this study and the main disease associated with neurological signs (23.7%). Recognizing the main diseases of cattle in this region will promote the adoption of prophylactic measures to minimize their occurrence and manage treatment to avoid economic losses and decreased productivity of herds.
    Schlagwörter Retrospective study ; ruminants ; cattle ; risk factors ; diseases ; Veterinary medicine ; SF600-1100
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2023-05-01T00:00:00Z
    Verlag Colégio Brasileiro de Patologia Animal (CBPA)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: DMRT3 Allele Frequencies in Batida- and Picada-Gaited Donkeys and Mules in Brazil

    Mariana Herman / Amanda Manara Caceres / Ana Luísa H. Albuquerque / Raíssa O. Leite / César Erineudo T. Araújo / Diego José Z. Delfiol / Rogério A. Curi / Alexandre S. Borges / José P. Oliveira-Filho

    Animals, Vol 13, Iss 24, p

    2023  Band 3829

    Abstract: In Brazil, the production of mules with a comfortable gait primarily involves the breeding of marching saddle mules. This is achieved by crossing gaited Pêga donkeys with horses from the Mangalarga Marchador and Campolina breeds. The DMRT3 :g.22999655C>A ...

    Abstract In Brazil, the production of mules with a comfortable gait primarily involves the breeding of marching saddle mules. This is achieved by crossing gaited Pêga donkeys with horses from the Mangalarga Marchador and Campolina breeds. The DMRT3 :g.22999655C>A SNP is implicated in regulating gait phenotypes observed in various horse breeds, including the batida (CC) and picada (CA) gaits found in these horse breeds. We aimed to determine if genotypes influenced gait type in 159 mules and 203 donkeys genotyped for the DMRT3 SNP by PCR-RFLP analysis. About 47% of mules had the CC-genotype, while 53% had the CA-genotype. Donkeys predominantly had the CC-genotype (97%), and none had AA. Both CC- and CA-genotypes were evenly distributed among mules with the batida or picada gaits. In donkeys, the CC-genotype frequencies were consistent regardless of gait type. However, the CA-genotype was more common in picada-gaited donkeys than in batida-gaited donkeys. The prevalence of CA mules and the rare presence of the non-reference allele in donkeys align with previous findings in Mangalarga Marchador and Campolina horses. This suggests that the non-reference allele likely originated from the mares involved in donkey crosses. Our results also imply that factors beyond this variant, such as other genes and polymorphisms, influence gait traits in equids.
    Schlagwörter equids ; gait keeper ; locomotion pattern ; genotype effect ; Brazil ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Serial measurements of Paraoxonase-1 (PON-1) activity in horses with experimentally induced endotoxemia

    Donatella Scavone / Micaela Sgorbini / Alexandre S. Borges / José P. Oliveira-Filho / Valentina Vitale / Saverio Paltrinieri

    BMC Veterinary Research, Vol 16, Iss 1, Pp 1-

    2020  Band 7

    Abstract: Abstract Background Paraoxonase-1 (PON-1) is an antioxidant enzyme, whose activity decreases during the acute phase response in many species. Little is known about PON-1 and its role as a negative acute phase protein during septic inflammation in horses, ...

    Abstract Abstract Background Paraoxonase-1 (PON-1) is an antioxidant enzyme, whose activity decreases during the acute phase response in many species. Little is known about PON-1 and its role as a negative acute phase protein during septic inflammation in horses, but promising findings about its utility in diagnosing SIRS and predicting the outcome in diseased horses, were recently highlighted. The objective of the study was to investigate the behaviour of PON-1 in horses after experimentally induced endotoxemia. To this aim, PON-1 activity was measured on 66 plasma samples collected from six clinically healthy mares, previously included in another study, before and at multiple time points between 12 and 240 h after intravenous infusion of Escherichia coli O55:B5 lipopolysaccharide (LPS). Results Compared with baseline values, a progressive transient decrease of PON-1 activity was observed starting from 24 h post-infusion, with lowest values observed between 3 to 7 days post-infusion, followed by a normalisation to pre-infusion levels the tenth day. Conclusions The results of this study suggest that measurement and monitoring of PON-1 activity might be useful to evaluate progression and recovery from endotoxemia in horses. Further studies in horses with naturally occurring sepsis are warranted.
    Schlagwörter Equine ; Inflammation ; Oxidative stress ; Veterinary medicine ; SF600-1100
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2020-11-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Clinical findings of equine leukoencephalomalacia

    Lukas G. Albertino / Natália M. Dias / Juliana J. Moreira / José P. Oliveira-Filho / Regina K. Takahira / Renée Laufer-Amorim / Alexandre S. Borges / Rogério M. Amorim

    Pesquisa Veterinária Brasileira, Vol

    2021  Band 41

    Abstract: ABSTRACT: Equine leukoencephalomalacia (LEM) is a disease caused by the ingestion of food, especially corn, contaminated by fumonisin, a Fusarium verticillioides (synonymous with F. moniliforme) metabolite. The clinical signs of brain injuries have an ... ...

    Abstract ABSTRACT: Equine leukoencephalomalacia (LEM) is a disease caused by the ingestion of food, especially corn, contaminated by fumonisin, a Fusarium verticillioides (synonymous with F. moniliforme) metabolite. The clinical signs of brain injuries have an acute onset and rapid evolution. This study aimed to describe the clinical findings in 11 animals diagnosed with LEM, including cerebrospinal fluid (CSF) analysis. Of these animals, 91% (10/11) were horses, and only 9% (1/11) were asinine. The clinical localization of the lesions was 64% (7/10) cerebral, manifested mainly by altered mental state and behavioral disturbance, and 36% (4/11) were brainstem lesions, manifested by incoordination, head tilt, nystagmus, facial hypoalgesia, difficulty in apprehension, chewing, and swallowing food. Postmortem findings revealed that 82% (9/11) of the lesions were in the cerebrum and 18% (2/11) in the brainstem. CSF findings, such as xanthochromia (43%, 3/7), hyperproteinorrachia (50%, 3/6), and pleocytosis (43%, 3/7) were observed. The affected animals showed neurological signs that were compatible with cerebral and/or brainstem injuries. The CSF from animals with LEM may present with xanthochromia, hyperproteinorrachia, and pleocytosis, reinforcing the fact that this disease should be included in the differential diagnosis of encephalomyelopathies.
    Schlagwörter Leukoencephalomalacia ; equine ; epidemiological aspects ; clinical aspects ; Veterinary medicine ; SF600-1100
    Thema/Rubrik (Code) 630 ; 610
    Sprache Englisch
    Erscheinungsdatum 2021-11-01T00:00:00Z
    Verlag Colégio Brasileiro de Patologia Animal (CBPA)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Occurrence of Salmonella spp. in fecal samples from foals with and without diarrhea in the state of São Paulo

    Pollyana R.C. Braga / Roberta M. Basso / Lorrayne S.A. Martins / Marcio G. Ribeiro / Ariadne F. Amarante / Monique R.T. Casas / Alessandra F.C. Nassar / Juliano G. Pereira / José Carlos F. Pantoja / Fabricio M. Cerri / Fábio S. Possebon / José P. Oliveira-Filho / Alexandre S. Borges

    Pesquisa Veterinária Brasileira, Vol

    microbiological diagnosis, antimicrobial susceptibility profile, and molecular detection

    2023  Band 43

    Abstract: ABSTRACT: The present study investigated Salmonella spp. in the feces of 200 foals up to one year of age (100 with clinical signs of diarrhea and 100 without clinical signs of diarrhea). Bacteriological culture, serotyping, antimicrobial susceptibility, ... ...

    Abstract ABSTRACT: The present study investigated Salmonella spp. in the feces of 200 foals up to one year of age (100 with clinical signs of diarrhea and 100 without clinical signs of diarrhea). Bacteriological culture, serotyping, antimicrobial susceptibility, and real-time PCR (qPCR SYBR® Green or a TaqMan®) for detecting the invA gene (with and without a selective pre-enrichment step in tetrathionate broth) were performed. Bacterial culture revealed 15% (n=30) of positive animals (21 animals with diarrhea and nine without diarrhea). Among the 30 isolates, 13 different serovars were identified: S. Infantis, S. Minnesota, S. I.4,5,12:i:-; S. Anatum, S. Cerro, S. Oranienburg, S. Braenderup, S. Give, S. Newport, S. IIIb 61:c:z35, S. 109:-:1.5, S. I.4.12:d:-, S. I.6.8:-:-. Multidrug resistance was found in 43.33% (n=13) of the isolates, with one isolate obtained from animals without diarrhea and 12 isolates from animals with diarrhea. All qPCR techniques used in the study classified more samples as positive for Salmonella spp. than the bacterial culture of feces. In addition, all qPCR techniques detected more positive animals in the diarrhea group than in the diarrhea-free group. The results confirm the utility of the qPCR method without the pre-enrichment step in tetrathionate as a rapid test for Salmonella spp. in carrier animals. In animals with clinical signs of diarrhea, it can be combined with bacterial culture (antimicrobial susceptibility testing and serotyping). The isolation of Salmonella spp. in nine animals without diarrhea confirms the importance of asymptomatic carrier animals in the epidemiology of the disease. The multidrug resistance observed highlights the importance of rational antimicrobial use in horses and adopting biosecurity protocols that are efficacious in controlling the spread of infections between animals and zoonotic transmission in farms.
    Schlagwörter Horses ; faeces ; invA gene ; multidrug resistance ; serovars ; Salmonella spp ; Veterinary medicine ; SF600-1100
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2023-08-01T00:00:00Z
    Verlag Colégio Brasileiro de Patologia Animal (CBPA)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Canine POMC deletion (P187fs) allele frequency in Labrador Retrievers in Brazil

    Natalia O. Lourenço / Ana Luísa H. Albuquerque / Roberta M. Basso / Anelize S. Trecenti / Lukas G. Albertino / Alessandra Melchert / Alexandre S. Borges / José P. Oliveira-Filho

    Pesquisa Veterinária Brasileira, Vol 39, Iss 11, Pp 909-

    2019  Band 914

    Abstract: ABSTRACT: The Labrador Retriever is among the main breeds with the greatest predisposition to obesity. Several factors, especially the interrelationships between food management, exercise and social factors; influence the likelihood of a dog becoming ... ...

    Abstract ABSTRACT: The Labrador Retriever is among the main breeds with the greatest predisposition to obesity. Several factors, especially the interrelationships between food management, exercise and social factors; influence the likelihood of a dog becoming obese. Furthermore, genetic factors are also responsible for obesity in dogs, and in Labrador Retriever, a frameshift mutation (P187fs) in pro-opiomelanocortin (POMC) gene is strongly associated with obesity. There is no knowledge of studies that have previously evaluated the prevalence of the canine POMC deletion (P187fs) in Brazilian Labrador Retriever. Therefore, the objective of this study was to investigate this mutation in Labrador Retriever dogs in Brazil. Of the 108 Labrador Retrievers that were assessed in this study, 59 were from a previous study, composed by animals assisted in a veterinary hospital with unknown lineage, and 49 were from a prospective study, composed of 19 pet and 30 assistance/rescue Labrador Retriever dogs. The obesity risk and appetite questionnaire were applied, with some modifications, to tutors of the animals used in the prospective study. Fragments of the DNA, containing the mutation, were amplified by PCR and submitted to direct gene sequencing. The allele frequency of the mutation was 21.3% and was out of Hardy-Weinberg equilibrium (P<0.05). Using only the data of animals with known lineage, the presence of the mutated allele was higher in the Assistance/rescue Group than Pet Group (P<0.01), furthermore, the allele frequencies observed in Assistance Group (31.7%) was out of Hardy-Weinberg equilibrium (P<0.05), while that in the Pet Group (18.4%) was in equilibrium (P>0.05). Although the mutation has increased the food-motivation in the assistance/rescue dogs, other variables, especially frequent exercising, favored that these animals maintained the ideal body weight (body condition score = 5). In summary, the Hardy-Weinberg disequilibrium observed in the allele distribution of the deletion POMC_P187fs in this study, ...
    Schlagwörter Canine POMC ; P187fs ; allele frequency ; Labrador Retriever ; Brazil ; gene ; mutation ; dogs ; obesity ; prevalence ; Veterinary medicine ; SF600-1100
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2019-12-01T00:00:00Z
    Verlag Colégio Brasileiro de Patologia Animal (CBPA)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Allele Frequency of the C.5G>A Mutation in the PRCD Gene Responsible for Progressive Retinal Atrophy in English Cocker Spaniel Dogs

    Larissa R. Andrade / Amanda M. Caceres / Anelize S. Trecenti / Claudia Valeria S. Brandão / Micaella G. Gandolfi / Evian V. Aguiar / Danilo G.A. Andrade / Alexandre S. Borges / Jose P. Oliveira-Filho

    Animals, Vol 9, Iss 10, p

    2019  Band 844

    Abstract: Progressive retinal atrophy (PRA) due to the c.5G>A mutation in the progressive rod−cone degeneration ( PRCD ) gene is an important genetic disease in English cocker spaniel (ECS) dogs. Because the prevalence of this disease has not been verified in ... ...

    Abstract Progressive retinal atrophy (PRA) due to the c.5G>A mutation in the progressive rod−cone degeneration ( PRCD ) gene is an important genetic disease in English cocker spaniel (ECS) dogs. Because the prevalence of this disease has not been verified in Brazil, this study aimed to evaluate the allele frequency of the c.5G>A mutation in the PRCD gene. Purified DNA from 220 ECS dogs was used for genotyping, of which 131 were registered from 18 different kennels and 89 were unregistered. A clinical eye examination was performed in 28 of the genotyped animals; 10 were homozygous mutants. DNA fragments containing the mutation region were amplified by PCR and subjected to direct genomic sequencing. The prcd-PRA allele frequency was 25.5%. Among the registered dogs, the allele frequency was 14.9%; among the dogs with no history of registration, the allele frequency was 41%. Visual impairment was observed in 80% (8/10) of the homozygous mutant animals that underwent clinical eye examination. The high mutation frequency found in this study emphasizes the importance of genotyping ECSs as an early diagnostic test, especially as part of an informed breeding program, to avoid clinical cases of PRA.
    Schlagwörter diagnosis ; genetic disease ; genotyping ; prcd-pra ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2019-10-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Prevalence study of SNP c.421G>T in the ADAMTS2 gene responsible for dermatosparaxis in White Dorper sheep in Brazil

    Danilo G.A. Andrade / Felipe M. Dalanezi / Anelize S. Trecenti / Paulo Henrique J. Cunha / Alexandre S. Borges / José P. Oliveira-Filho

    Pesquisa Veterinária Brasileira, Vol 36, Iss 2, Pp 73-

    2016  Band 76

    Abstract: Abstract: Dermatosparaxis is an autosomal recessive disorder of connective tissue; the disorder is clinically characterized by skin fragility and hyperextensibility. Dermatosparaxis in White Dorper sheep is caused by a single nucleotide polymorphism (SNP) ...

    Abstract Abstract: Dermatosparaxis is an autosomal recessive disorder of connective tissue; the disorder is clinically characterized by skin fragility and hyperextensibility. Dermatosparaxis in White Dorper sheep is caused by a single nucleotide polymorphism (SNP) (c.421G>T) in the ADAM metalloproteinase with thrombospondin type 1 motif, 2 (ADAMTS2) gene. The aim of this study was to investigate the prevalence of this SNP in a White Dorper herd in São Paulo state, Brazil. In this study, we collected blood DNA samples from 303 White Dorper sheep and performed polymerase chain reaction to amplify the SNP region. The samples were sequenced to determine the presence of the SNP in the ADAMTS2 gene. The SNP prevalence in the studied population was 15.5%; this finding indicates that more effective control measures should be used to prevent the inheritance of SNP c.421G>T in the ADAMTS2 gene in Brazilian White Dorper herds.
    Schlagwörter Astenia cutânea ; autossômica recessiva ; PCR ; White Dorper ; ovinos ; Veterinary medicine ; SF600-1100
    Sprache Englisch
    Erscheinungsdatum 2016-02-01T00:00:00Z
    Verlag Colégio Brasileiro de Patologia Animal (CBPA)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Ocorrência do SNP c.767G>T no gene DNM1responsável pelo colapso induzido pelo exercício em cães da raça Labrador Retriever no Estado de São Paulo

    Roberta M. Basso / José P. Oliveira-Filho / Mariana I.P. Palumbo / Luiza S. Zakia / João P. Araújo Jr / Alexandre S. Borges

    Pesquisa Veterinária Brasileira, Vol 35, Iss 5, Pp 486-

    2015  Band 490

    Abstract: Resumo:O colapso induzido pelo exercício (EIC) é considerado uma síndrome autossômica recessiva que afeta principalmente cães da raça Labrador Retriever. A doença é caracterizada por fraqueza muscular e colapso após exercício intenso. Usualmente, ocorre ... ...

    Abstract Resumo:O colapso induzido pelo exercício (EIC) é considerado uma síndrome autossômica recessiva que afeta principalmente cães da raça Labrador Retriever. A doença é caracterizada por fraqueza muscular e colapso após exercício intenso. Usualmente, ocorre recuperação clínica após o episódio, mas alguns animais podem vir a óbito. Os sinais clínicos são decorrentes do polimorfismo de base única (SNP) c.767G>T no gene Dynamin 1 (DNM1). O objetivo deste trabalho foi determinar a ocorrência deste SNP em 321 cães da raça Labrador Retriever do Estado de São Paulo. Primers específicos para a amplificação de todo o exon 6 do gene DNM1 foram usados nas PCRs utilizando DNA a partir de amostras de sangue ou swab bucal, a avaliação final foi realizada com sequenciamento direto dos produtos da PCR. Dentre os 321 animais estudados, 3,4 % (11/321) eram homozigotos para o SNP c.767G>T no gene DNM1 e 24,6% (79/321) eram heterozigotos. Somente um dos 11 animais homozigotos apresentavam sinais clínicos compatíveis com a EIC. Este é o primeiro estudo sobre a ocorrência deste SNP no Brasil e considerando que quase 25% dos animais estudados eram heterozigotos, a genotipagem dos animais para este SNP pode ser importante antes dos acasalamentos para cães desta raça. A EIC deve ser considerada nos diagnósticos diferenciais de enfermidades neuromusculares em cães da raça Labrador Retriever.
    Schlagwörter Cães ; Labrador Retriever ; DNM1 ; exercício ; PCR ; sequenciamento ; Veterinary medicine ; SF600-1100
    Sprache Englisch
    Erscheinungsdatum 2015-05-01T00:00:00Z
    Verlag Colégio Brasileiro de Patologia Animal (CBPA)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Freund's adjuvant-induced inflammation

    José P. Oliveira-Filho / Peres R. Badial / Paulo Henrique J. Cunha / Ana Paula Bordon / João P. Araujo Jr / Thomas J. Divers / Nena J. Winand / Alexandre S. Borges

    Pesquisa Veterinária Brasileira, Vol 34, Iss 1, Pp 51-

    clinical findings and its effect on hepcidin mRNA expression in horses

    2014  Band 56

    Abstract: Hypoferremia observed during systemic inflammatory disorders is regulated by hepcidin. Hepcidin up-regulation is particularly important during acute inflammation, as it restricts the availability of iron, which is necessary for pathogenic microorganism ... ...

    Abstract Hypoferremia observed during systemic inflammatory disorders is regulated by hepcidin. Hepcidin up-regulation is particularly important during acute inflammation, as it restricts the availability of iron, which is necessary for pathogenic microorganism growth before adaptive immunity occurs. The aim of this study was to evaluate the clinical findings and hepatic hepcidin mRNA expression in horses using a Freund's complete adjuvant (FCA) model of inflammation. The expression of hepcidin mRNA in the liver was determined in healthy horses following two intramuscular injections of FCA at 0 h and 12 h. Plasma iron and fibrinogen concentrations were measured at multiple time points between 0 h and 240 h post-FCA injection (PI). Hepcidin mRNA expression was determined by RT-qPCR using liver biopsy samples performed at 0 h (control), 6 h and 18 h PI. The mean plasma fibrinogen level was significantly different from the control values only between 120 and 216 h PI. The mean plasma iron level was significantly lower than the control between 16 and 72 h PI, reaching the lowest levels at 30 h PI (33 % of the initial value), and returned to the reference value from 96 h PI to the end of the experiment. Hepcidin mRNA expression increased at 6 h PI and remained high at 18 h PI. The iron plasma concentration was an earlier indicator of inflammatory processes in horses when compared with fibrinogen and might be useful for the early detection of inflammation in the horse. FCA administration caused the rapid onset of hypoferremia, and this effect was likely the result of up-regulated hepatic hepcidin gene expression. This study emphasizes the importance of hepcidin and iron metabolism during inflammation in horses.
    Schlagwörter Hepcidina ; Adjuvante completo de Freund ; reagente de fase aguda ; inflamação ; metabolismo do ferro ; cavalo ; Animal culture ; SF1-1100 ; Agriculture ; S
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2014-01-01T00:00:00Z
    Verlag Colégio Brasileiro de Patologia Animal - CBPA
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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