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  1. Article: Bypassing conventional anaesthetics: Dexmedetomidine sedation in MEGDEL syndrome.

    Dhanaboopathy, Kishorkumar / Joselyn, Anita S

    Indian journal of anaesthesia

    2022  Volume 66, Issue 2, Page(s) 152–153

    Language English
    Publishing date 2022-02-24
    Publishing country India
    Document type Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.ija_696_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Epidural catheter migration in non-obstetric adult surgical patients: A prospective, observational, cohort study.

    Jose, Riya / Greenlin, Latha / Isac, Divya / Yadav, Bijesh / Joselyn, Anita Shirley

    Indian journal of anaesthesia

    2023  Volume 67, Issue 6, Page(s) 509–514

    Abstract: Background and aims: Epidural catheter migration is a well-described complication in the obstetric population, though its significance in the non-obstetric surgical population is not known. The purpose of this study was to explore the incidence of ... ...

    Abstract Background and aims: Epidural catheter migration is a well-described complication in the obstetric population, though its significance in the non-obstetric surgical population is not known. The purpose of this study was to explore the incidence of epidural catheter migration in a non-obstetric adult surgical cohort, assess the factors associated with migration and analyse complications among patients with and without catheter migration.
    Methods: In this single-centre, prospective, observational study, the acute pain services team collected data over 12 months on consecutive, adult non-obstetric surgical patients who received an epidural catheter for postoperative pain management. Details of epidural catheter insertion, fixation, migration and complications were collected from the first to the fourth postoperative day.
    Results: Of the 510 patients recruited, epidural catheter migration was noted in 233 patients (45.7%), of which 152 (65.2%) migrated outwards and the rest migrated inwards. Also, 72 (30.9%) and 86 (31.05%) complications were noted in the groups with and without catheter migration, respectively. The most frequent complications noted were inadequate analgesia, unilateral sensory block, motor block and hypotension in both groups. We did not find any correlation between the frequency of epidural catheter migration and demographic factors.
    Conclusions: Epidural catheter migration is a sizeable postoperative occurrence in non-obstetric surgical patients. Factors that might play a role in catheter migration could not be established in this study. There is an almost similar frequency of complications noted among patients with and without catheter migration, with the most common being inadequate analgesia in both groups.
    Language English
    Publishing date 2023-06-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.ija_830_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Development and validation of Daycare Anesthesia Satisfaction (DAS) questionnaire to assess patient's satisfaction with daycare anesthesia.

    Joselyn, Anita Shirley / Suhag, Kanika / Joy, Melvin / Jeyaseelan, L

    Journal of anaesthesiology, clinical pharmacology

    2022  Volume 38, Issue 3, Page(s) 474–479

    Abstract: Background and aims: The patient's satisfaction can be considered as a unique indicator of the quality of healthcare provided. The advantages of patient satisfaction surveys rely heavily on using standardized, psychometrically tested data collection ... ...

    Abstract Background and aims: The patient's satisfaction can be considered as a unique indicator of the quality of healthcare provided. The advantages of patient satisfaction surveys rely heavily on using standardized, psychometrically tested data collection approaches. There is a lack of a proper, psychometrically robust instrument to evaluate the patient's perioperative satisfaction following all types of anesthesia in daycare facility. Hence, this study aimed to develop a Daycare Anesthesia Satisfaction (DAS) questionnaire to measure the patient's satisfaction with the experience of daycare anesthesia services.
    Material and methods: A preliminary pool of questions was generated from research literature, expert consultations, and pilot tested on patients. The internal consistency and reliability of the preliminary questionnaire was evaluated by calculating Cronbach's alpha, intraclass correlation coefficient (ICC), and feasibility with the formation of a final 27-item questionnaire. In the next step, the questionnaire was distributed to a larger group of patients in the phase 2 of postanesthesia care unit (PACU). The results were subjected to confirmatory factor analysis to determine the goodness of fit of the questions under each domain.
    Results: The internal consistency of the preliminary questionnaire as measured by Cronbach's alpha was 0.929. Intraclass correlation coefficient measured for test-retest reliability was 0.97 (95% confidence interval [CI]). Feasibility was confirmed, as 75% of the patients could fill the questionnaire within 15 min. In the second step of confirmatory factor analysis (CFA), questionnaire has been shown to have goodness of fit with Bentler's comparative fit index (CFI) of 0.99 that is greater than the suggested cutoff of 0.90. The root mean square error of approximation (RMSEA) of 0.09 is also close to the suggested cutoff of 0.06.
    Conclusion: This systematically developed and validated, 27-item DAS questionnaire can be tentatively recommended to be used to measure patient's satisfaction with day care anesthesia services following all types of surgical procedures, under various types of anesthesia.
    Language English
    Publishing date 2022-02-24
    Publishing country India
    Document type Journal Article
    ZDB-ID 1401760-x
    ISSN 0970-9185
    ISSN 0970-9185
    DOI 10.4103/joacp.JOACP_563_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A cross sectional, observational study to evaluate the surgeons' knowledge and perspective on preoperative fasting guidelines in a tertiary care teaching hospital in Southern India.

    Paul, Pallapati Aparanjit / Joselyn, Anita Shirley / Pande, Priyanka Vandana / Gowri, Mahasampath

    Journal of anaesthesiology, clinical pharmacology

    2022  Volume 38, Issue 3, Page(s) 434–439

    Abstract: Background and aims: The preoperative fasting orders given by the Anesthesiologists as per ASA and Enhanced Recovery After Surgery protocol, are often modified by the surgeons, for practical convenience, which can end up with patients being starved for ... ...

    Abstract Background and aims: The preoperative fasting orders given by the Anesthesiologists as per ASA and Enhanced Recovery After Surgery protocol, are often modified by the surgeons, for practical convenience, which can end up with patients being starved for prolonged periods of time. Hence, this study was conducted among various specialty surgical colleagues, to evaluate the knowledge and their perspective regarding patients' preoperative fasting guidelines.
    Material and methods: A validated questionnaire was distributed to 68 surgeons belonging to various surgical specialties, which included consultants and postgraduate residents. The surgeons were grouped as surgeons operating only on children, only on adults, and on adults and children (mixed). Data were summarized using the mean (SD)/median for continuous variables and categorical data were expressed as frequency and percentage. The difference in knowledge score, among the surgeons of three groups, was analyzed using ANOVA, with Bonferroni as post hoc.
    Results: This study shows an overall decrease in knowledge (score of 6.13 ± 1.74) about preoperative fasting guidelines among surgeons. We found that the level of knowledge about preoperative fasting guidelines and complications was higher among surgeons who operate only on children (score of 7.05) as compared to surgeons operating only on adults (score 5.5) and adults and children (mixed) (score 6.1), which was statistically significant (
    Conclusion: Preoperative fasting orders for all surgical patients, especially for vulnerable patients such as children and geriatrics, should be administered by the anesthesiologist or surgeon who is familiar with fasting guidelines. We intend to raise the awareness of fasting guidelines of surgical colleagues by putting up placards and posters in the wards.
    Language English
    Publishing date 2022-06-15
    Publishing country India
    Document type Journal Article
    ZDB-ID 1401760-x
    ISSN 0970-9185
    ISSN 0970-9185
    DOI 10.4103/joacp.JOACP_413_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Preoperative anxiety among patients scheduled for elective surgical procedures during the COVID-19 pandemic - A cross-sectional study in a tertiary care teaching hospital in India.

    Viola, Chelsea Thanga / Joselyn, Anita Shirley / Sukumar, Ashwin / Sahajanandan, Raj

    Indian journal of anaesthesia

    2021  Volume 65, Issue 8, Page(s) 619–625

    Language English
    Publishing date 2021-08-25
    Publishing country India
    Document type Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.ija_594_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Implementation and outcomes of enhanced recovery protocols in pediatric surgery: a systematic review and meta-analysis.

    Loganathan, Arun Kumar / Joselyn, Anita Shirley / Babu, Malavika / Jehangir, Susan

    Pediatric surgery international

    2021  Volume 38, Issue 1, Page(s) 157–168

    Abstract: Background: This systematic review examines the feasibility and safety of implementing Enhanced recovery after Surgery (ERAS) protocols in children.: Study design: A systematic search of Medline, PubMed, and the Cochrane library for papers describing ...

    Abstract Background: This systematic review examines the feasibility and safety of implementing Enhanced recovery after Surgery (ERAS) protocols in children.
    Study design: A systematic search of Medline, PubMed, and the Cochrane library for papers describing ERAS implementation in children between January 2000 and January 2021. The systematic review was performed according to the PRISMA statement. The meta-analysis was done using R Software (Ver 4.0.2). p value of < 0.05 was considered statistically significant.
    Results: Sixteen studies, describing a total of 1723 patients, were included in the meta-analysis. An average of 15 (range 11-16) relevant components were implemented with an overall compliance close to 84%. The time to initiate feeds and reach full enteral nutrition was reduced in ERAS group with mean difference (MD) of - 21.20 h (95% CI - 22.80, - 19.59, p < 0.01), and - 2.20 days (95% CI - 2.72, - 1.71, p < 0.01), respectively. The use of opioids for postoperative analgesia was reduced with MD of -0.86 morphine equivalents mg/kg (95% CI - 1.40, - 0.32, p < 0.01). The length of hospital stay showed a significant reduction with MD of -2.54 days (95% CI - 2.94, - 2.13, p < 0.01). There was no difference in the complication and readmission rates between the groups.
    Conclusion: ERP implementation in pediatric perioperative care is a viable option in a variety of surgical settings. There is clear evidence of a decrease in hospital stay duration with no increase in complication or readmission rates. The length of hospital stay reduced in inverse proportion to the number of ERAS elements implemented. Parental satisfaction is increased by initiating enteral feeding early, minimizing catheter and drain use, and reducing opioid use.
    MeSH term(s) Analgesics, Opioid/therapeutic use ; Child ; Clinical Protocols ; Enhanced Recovery After Surgery ; Humans ; Length of Stay ; Morphine ; Perioperative Care ; Postoperative Complications
    Chemical Substances Analgesics, Opioid ; Morphine (76I7G6D29C)
    Language English
    Publishing date 2021-09-15
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-021-05008-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Improving safety in anesthetized patients undergoing magnetic resonance imaging-Concept of time-out in the MRI suite and measures to improve adherence to time-out protocol.

    Joselyn, Anita Shirley / Teddy, Dan Anna / Jose, Riya / Shanthini, Sharon / Joseph, Lallu / Rai, Ekta / Williams, Aparna

    Paediatric anaesthesia

    2023  Volume 33, Issue 5, Page(s) 370–376

    Abstract: Background: The time-out protocol introduced by the Joint Commission is an important tool to prevent adverse events and improve safety in various health-care environments. However, its implementation and utilization involve human, social, behavioral as ... ...

    Abstract Background: The time-out protocol introduced by the Joint Commission is an important tool to prevent adverse events and improve safety in various health-care environments. However, its implementation and utilization involve human, social, behavioral as well as system issues.
    Aims: The SMART aim of the current project was to increase the utilization of the time-out protocol to more than 80% from baseline of 13%, over 6-month period in all the magnetic resonance imaging (MRI) procedures performed at a tertiary care, teaching institute in South India.
    Methods: The Plan, Do, Study, Act (PDSA) cycle and root cause analysis strategies were utilized in this quality improvement initiative. The time-out protocol was modified for MRI environment and put into practice to improve safety. Six months after the initiation of this safety protocol, our audit showed only a 13% compliance to the time-out protocol. A multimodal strategy was utilized by involving all the stakeholders, educational interventions, and placing reminders for following the time-out protocol, to affect change and achieve improvement in safety.
    Results: The compliance to time-out protocol increased from 13% to 86% and the run chart showed that a special cause variation indicated by six points above the centerline at 86%. When analyzing individual components of the time-out, the greatest improvement was noted in the ferromagnetic check of the personnel involved, namely, the Anesthesiologist, radiographer, and anesthesia technician. There were no delays in the list because of adherence to the time-out protocol.
    Conclusion: Time-out protocol in an MRI suite provides a final check to the anesthesia team before the anesthetized patient is wheeled into MR gantry. Using quality improvement methodology, we increased the compliance of time-out protocol in the magnetic resonance imaging environment. Our study is an example how other institutions in India and elsewhere can adapt similar improvement strategies to enhance patient safety.
    MeSH term(s) Humans ; Anesthesia ; Anesthesiologists ; Magnetic Resonance Imaging/methods ; Quality Improvement ; Patient Safety
    Language English
    Publishing date 2023-01-16
    Publishing country France
    Document type Journal Article
    ZDB-ID 1086049-6
    ISSN 1460-9592 ; 1155-5645
    ISSN (online) 1460-9592
    ISSN 1155-5645
    DOI 10.1111/pan.14627
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A prospective observational study to evaluate the magnitude of temperature changes in children undergoing elective MRI under general anesthesia.

    Ruth, Merlin S / Sridharan, Nivetha / Rai, Ekta / Joselyn, Anita S

    Saudi journal of anaesthesia

    2020  Volume 14, Issue 2, Page(s) 200–205

    Abstract: Context: Induction of general anesthesia and mandatory low-ambient temperature in the magnetic resonance imaging (MRI) suite renders the pediatric patient prone to fall in core temperature. Previously done studies have shown mixed results with core ... ...

    Abstract Context: Induction of general anesthesia and mandatory low-ambient temperature in the magnetic resonance imaging (MRI) suite renders the pediatric patient prone to fall in core temperature. Previously done studies have shown mixed results with core temperature showing both rise and fall.
    Aims: The aim of this study is to evaluate which effect, hypothermia or hyperthermia, predominates in children anesthetized for MRI. Is the change in temperature the same across age groups and for different MRI scanners?.
    Settings and design: Prospective, observational study in a tertiary care teaching hospital.
    Subjects and methods: Two hundred and fifty children of age between 1 month and 16 years scheduled for MRI under propofol-based total intravenous anesthesia (TIVA) were recruited. A baseline core temperature (pre-scan) was recorded with the pediatric nasopharyngeal temperature probe after induction of anesthesia and also after the scan in the recovery room.
    Results: The study shows that there is a significant fall in temperature of 1.022°C (CI = 0.964, 1.081) following MRI (
    Conclusion: Vigilant temperature preservation strategies have to be maintained during the time the anesthetized child is present in the MRI suite. MRI compatible active warming devices are warranted especially in high turnover centers.
    Language English
    Publishing date 2020-03-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2562174-9
    ISSN 0975-3125 ; 1658-354X
    ISSN (online) 0975-3125
    ISSN 1658-354X
    DOI 10.4103/sja.SJA_791_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Simulation with a colour indicator to help reduce contamination during airway management in COVID-19 times: An experience from a tertiary centre in India.

    George, Leah R / George, Smitha E / Dhawan, Ira / Babu, Malavika / Sahajanandan, Raj / Joselyn, Anita S

    Indian journal of anaesthesia

    2021  Volume 65, Issue 11, Page(s) 820–829

    Abstract: Background and aims: The coronavirus disease 2019 (COVID-19) pandemic has initiated modified protocols for aerosol-generating procedures. A simulation study using dye was conducted to highlight contamination at intubation and extubation and to encourage ...

    Abstract Background and aims: The coronavirus disease 2019 (COVID-19) pandemic has initiated modified protocols for aerosol-generating procedures. A simulation study using dye was conducted to highlight contamination at intubation and extubation and to encourage adherence to the new COVID-19 protocol among anaesthesia personnel in our institution.
    Methods: A video demonstrating the new COVID-19 protocols was circulated in the Department of Anaesthesiology a week prior to the study. Thirty teams, each comprising an anaesthesia resident and a staff technician, were enroled. Each team was asked to demonstrate the steps of preparation, intubation and extubation on a mannequin in a COVID-19 scenario. Checklists were used to assess points of contamination and adherence to the protocols. Following debriefing, a repeat simulation was conducted. The use of a dye highlighted the points of contamination. The study subjects provided feedback on the usefulness of the session and practical difficulties encountered in adapting to the new protocols.
    Results: The average contamination scores decreased by 3.4 (95% confidence interval (CI): 2.4-4.4,
    Conclusion: Simulation with a low-fidelity mannequin by using colour indicator for secretions is an effective teaching tool to reduce health hazards during airway management in COVID-19 times.
    Language English
    Publishing date 2021-11-23
    Publishing country India
    Document type Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.ija_768_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Intravenous clonidine as a part of balanced anaesthesia for controlled hypotension in functional endoscopic sinus surgery: A randomised controled trial.

    Jiwanmall, Meghna / Joselyn, Anita Shirley / Kandasamy, Subramani

    Indian journal of anaesthesia

    2016  Volume 61, Issue 5, Page(s) 418–423

    Abstract: Background and aims: Controlled hypotension with balanced anaesthesia minimises blood loss. This study was done to evaluate the effectiveness of intravenous clonidine as a single bolus dose to establish controlled hypotension during functional ... ...

    Abstract Background and aims: Controlled hypotension with balanced anaesthesia minimises blood loss. This study was done to evaluate the effectiveness of intravenous clonidine as a single bolus dose to establish controlled hypotension during functional endoscopic sinus surgery (FESS).
    Methods: This randomised, double-blind, placebo-controlled study was done in a tertiary hospital in India. Sixty American Society of Anesthesiologists physical status I and II patients (18-65 years) undergoing FESS were randomly allocated to one of the two groups. Placebo group (group A,
    Results: Target MAP was easily achieved in clonidine group as against the placebo group (
    Conclusion: Clonidine is effective in achieving controlled hypotension in patients undergoing FESS. It reduces intra-operative blood loss, requirement of additional hypotensive drugs, improves the surgical field and offers good analgesia without significant side effects.
    Language English
    Publishing date 2016-10-26
    Publishing country India
    Document type Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.IJA_58_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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