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  1. Article ; Online: Ambulatory microdose induction of buprenorphine-naloxone in two adolescent patients with sickle cell disease.

    Buchheit, Bradley M / Joslin, Timothy / Turner, Helen N / Wong, Trisha E

    Pediatric blood & cancer

    2020  Volume 68, Issue 1, Page(s) e28766

    Abstract: Sickle cell disease (SCD) is a hematologic disorder defined by presence of sickle-shaped red blood cells that can occlude blood vessels and cause tissue ischemia and pain. Treating SCD pain adequately and safely is difficult given today's opioid climate. ...

    Abstract Sickle cell disease (SCD) is a hematologic disorder defined by presence of sickle-shaped red blood cells that can occlude blood vessels and cause tissue ischemia and pain. Treating SCD pain adequately and safely is difficult given today's opioid climate. Buprenorphine-naloxone has been described as an alternative option to treat chronic pain in the adult literature; however, it historically required discontinuation of full-agonist opioids before initiation, resulting in opioid withdrawal. Herein we present two adolescents with SCD who successfully weaned off large doses of full-agonist opioids by using microdose induction of buprenorphine-naloxone in clinic, without experiencing significant opioid withdrawal. Ambulatory microdose induction may remove hurdles that otherwise would discourage patients from trying this regimen while still controlling pain safely.
    MeSH term(s) Adolescent ; Adult ; Analgesics, Opioid/therapeutic use ; Anemia, Sickle Cell/complications ; Buprenorphine, Naloxone Drug Combination/therapeutic use ; Dose-Response Relationship, Drug ; Humans ; Male ; Pain/drug therapy ; Pain/etiology ; Pain/pathology ; Prognosis ; Young Adult
    Chemical Substances Analgesics, Opioid ; Buprenorphine, Naloxone Drug Combination
    Language English
    Publishing date 2020-10-27
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.28766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Storylines of family medicine III: core principles-primary care, systems and family.

    Ventres, William B / Stone, Leslie A / Joslin, Timothy A / Saultz, John W / Aldulaimi, Sommer / Gordon, Paul R / Lane, John C / Lee, Eric R / Prunuske, Jacob / Gildenblatt, Limor / Friedman, Michael H / Fogarty, Colleen T / McDaniel, Susan H / Rohrberg, Tessa / Odom, Amy

    Family medicine and community health

    2024  Volume 12, Issue Suppl 3

    Abstract: Storylines of Family ... ...

    Abstract Storylines of Family Medicine
    MeSH term(s) Humans ; Family Practice ; Physicians, Family ; Family ; Family Health ; Patient-Centered Care
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2986753-8
    ISSN 2009-8774 ; 2305-6983
    ISSN (online) 2009-8774
    ISSN 2305-6983
    DOI 10.1136/fmch-2024-002790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Expert Consensus Statement on Proficiency Standards for Dermoscopy Education in Primary Care.

    Tran, Tiffaney / Cyr, Peggy R / Verdieck, Alex / Lu, Miranda D / Ahrns, Hadjh T / Berry, Elizabeth G / Bowen, William / Braun, Ralph P / Cusick-Lewis, Joshua M / Doan, Hung Q / Donohue, Valerie L / Erlich, Deborah R / Ferris, Laura K / Harkemanne, Evelyne / Hartman, Rebecca I / Holt, James / Jaimes, Natalia / Joslin, Timothy A / Kabaeva, Zhyldyz /
    Liebman, Tracey N / Ludzik, Joanna / Marghoob, Ashfaq A / Simpson, Isac / Stein, Jennifer A / Stulberg, Daniel L / Tromme, Isabelle / Turnquist, Matthew J / Usatine, Richard P / Walker, Alison M / Walker, Bryan L / West, Robert F / Wilson, Megan L / Witkowski, Alexander / Wu, Dominic J / Seiverling, Elizabeth V / Nelson, Kelly C

    Journal of the American Board of Family Medicine : JABFM

    2023  Volume 36, Issue 1, Page(s) 25–38

    Abstract: Background: Primary care providers (PCPs) frequently address dermatologic concerns and perform skin examinations during clinical encounters. For PCPs who evaluate concerning skin lesions, dermoscopy (a noninvasive skin visualization technique) has been ... ...

    Abstract Background: Primary care providers (PCPs) frequently address dermatologic concerns and perform skin examinations during clinical encounters. For PCPs who evaluate concerning skin lesions, dermoscopy (a noninvasive skin visualization technique) has been shown to increase the sensitivity for skin cancer diagnosis compared with unassisted clinical examinations. Because no formal consensus existed on the fundamental knowledge and skills that PCPs should have with respect to dermoscopy for skin cancer detection, the objective of this study was to develop an expert consensus statement on proficiency standards for PCPs learning or using dermoscopy.
    Methods: A 2-phase modified Delphi method was used to develop 2 proficiency standards. In the study's first phase, a focus group of PCPs and dermatologists generated a list of dermoscopic diagnoses and associated features. In the second phase, a larger panel evaluated the proposed list and determined whether each diagnosis was reflective of a foundational or intermediate proficiency or neither.
    Results: Of the 35 initial panelists, 5 PCPs were lost to follow-up or withdrew; 30 completed the fifth and last round. The final consensus-based list contained 39 dermoscopic diagnoses and associated features.
    Conclusions: This consensus statement will inform the development of PCP-targeted dermoscopy training initiatives designed to support early cancer detection.
    MeSH term(s) Humans ; Melanoma/diagnosis ; Melanoma/pathology ; Dermoscopy/methods ; Skin Neoplasms/diagnostic imaging ; Skin ; Primary Health Care
    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2239939-2
    ISSN 1558-7118 ; 1557-2625
    ISSN (online) 1558-7118
    ISSN 1557-2625
    DOI 10.3122/jabfm.2022.220143R1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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