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  1. Article: Renal calculus at presentation in a child with Crohn's disease.

    Joy, Harriet M / Fairhurst, Joanna J / Beattie, R Mark

    Pediatric radiology

    2003  Volume 33, Issue 4, Page(s) 250–252

    Abstract: Genitourinary complications are relatively common in inflammatory bowel disease, with a reported incidence of 4-23%, although they more frequently occur in established disease. We present the case of a 12-year-old boy, already under investigation for ... ...

    Abstract Genitourinary complications are relatively common in inflammatory bowel disease, with a reported incidence of 4-23%, although they more frequently occur in established disease. We present the case of a 12-year-old boy, already under investigation for short stature, who only developed florid symptoms of colitis after removal of a large staghorn calculus. In all cases of childhood nephrolithiasis, the possibility of underlying inflammatory bowel disease needs to be considered.
    MeSH term(s) Child ; Crohn Disease/complications ; Crohn Disease/diagnostic imaging ; Humans ; Intestines/diagnostic imaging ; Kidney/diagnostic imaging ; Kidney Calculi/complications ; Kidney Calculi/diagnosis ; Kidney Calculi/diagnostic imaging ; Male ; Radiography ; Ultrasonography
    Language English
    Publishing date 2003-04
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 124459-0
    ISSN 1432-1998 ; 0301-0449
    ISSN (online) 1432-1998
    ISSN 0301-0449
    DOI 10.1007/s00247-002-0819-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Spectrum, risk factors and outcomes of neurological and psychiatric complications of COVID-19: a UK-wide cross-sectional surveillance study.

    Ross Russell, Amy L / Hardwick, Marc / Jeyanantham, Athavan / White, Laura M / Deb, Saumitro / Burnside, Girvan / Joy, Harriet M / Smith, Craig J / Pollak, Thomas A / Nicholson, Timothy R / Davies, Nicholas W S / Manji, Hadi / Easton, Ava / Ray, Stephen / Zandi, Michael S / Coles, Jonathan P / Menon, David K / Varatharaj, Aravinthan / McCausland, Beth /
    Ellul, Mark A / Thomas, Naomi / Breen, Gerome / Keddie, Stephen / Lunn, Michael P / Burn, John P S / Quattrocchi, Graziella / Dixon, Luke / Rice, Claire M / Pengas, George / Al-Shahi Salman, Rustam / Carson, Alan / Joyce, Eileen M / Turner, Martin R / Benjamin, Laura A / Solomon, Tom / Kneen, Rachel / Pett, Sarah / Thomas, Rhys H / Michael, Benedict D / Galea, Ian

    Brain communications

    2021  Volume 3, Issue 3, Page(s) fcab168

    Abstract: SARS-CoV-2 is associated with new-onset neurological and psychiatric conditions. Detailed clinical data, including factors associated with recovery, are lacking, hampering prediction modelling and targeted therapeutic interventions. In a UK-wide cross- ... ...

    Abstract SARS-CoV-2 is associated with new-onset neurological and psychiatric conditions. Detailed clinical data, including factors associated with recovery, are lacking, hampering prediction modelling and targeted therapeutic interventions. In a UK-wide cross-sectional surveillance study of adult hospitalized patients during the first COVID-19 wave, with multi-professional input from general and sub-specialty neurologists, psychiatrists, stroke physicians, and intensivists, we captured detailed data on demographics, risk factors, pre-COVID-19 Rockwood frailty score, comorbidities, neurological presentation and outcome.
    Language English
    Publishing date 2021-07-22
    Publishing country England
    Document type Journal Article
    ISSN 2632-1297
    ISSN (online) 2632-1297
    DOI 10.1093/braincomms/fcab168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: MRI assessment of basal ganglia iron deposition in Parkinson's disease.

    Wallis, Lauren I / Paley, Martyn N J / Graham, Jacqueline M / Grünewald, Richard A / Wignall, Emma L / Joy, Harriet M / Griffiths, Paul D

    Journal of magnetic resonance imaging : JMRI

    2008  Volume 28, Issue 5, Page(s) 1061–1067

    Abstract: Purpose: To estimate the levels of basal ganglia iron levels in Parkinson's disease (PD) using the PRIME MR sequence at 3.0 Tesla, in relation to patients' motor symptom severity.: Materials and methods: Seventy patients with PD and 10 healthy ... ...

    Abstract Purpose: To estimate the levels of basal ganglia iron levels in Parkinson's disease (PD) using the PRIME MR sequence at 3.0 Tesla, in relation to patients' motor symptom severity.
    Materials and methods: Seventy patients with PD and 10 healthy controls underwent assessment of movement and MR imaging. Mean R2' relaxation rates were recorded in the substantia nigra, frontal white matter and in the rostral, mid, and caudal putamen.
    Results: R2' relaxation rates were significantly higher in patients with PD than in healthy controls. R2' in the most affected substantia nigra correlated with PD patients' motor symptom severity, but not with disease duration. Neuroradiological observation revealed a rostral to caudal "gradient" of putaminal hypointensity. This was substantiated by the finding that the mid and caudal putamen showed significantly higher R2' relaxation rates, consistent with higher iron levels in PD relative to the healthy controls.
    Conclusion: MRI at 3.0 Tesla suggests that substantia nigra iron levels are increased and linked to the severity of motor symptoms experienced in PD. Findings consistent with increased iron levels in the PD putamen are shown, in a region-specific rostral to caudal gradient.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Algorithms ; Basal Ganglia/metabolism ; Basal Ganglia/pathology ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Iron/analysis ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Parkinson Disease/diagnosis ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; Reproducibility of Results ; Sensitivity and Specificity
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2008-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1146614-5
    ISSN 1522-2586 ; 1053-1807
    ISSN (online) 1522-2586
    ISSN 1053-1807
    DOI 10.1002/jmri.21563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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