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  1. Article: Histoséminaire : ouf, c’est positif ! De l’usage salvateur des biomarqueurs en pathologie mammaire : cas n

    Joyon, Natacha

    Annales de pathologie

    2022  Volume 42, Issue 4, Page(s) 302–307

    Title translation Histoseminar: Saved by a positive staining! About the use of diagnostic biomarkers in breast pathology: Case No. 3.
    MeSH term(s) Biomarkers, Tumor ; Breast ; Breast Neoplasms/diagnosis ; Female ; Humans ; Staining and Labeling
    Chemical Substances Biomarkers, Tumor
    Language French
    Publishing date 2022-01-31
    Publishing country France
    Document type Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2022.01.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1652: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Histoséminaire : ouf, c’est positif ! De l’usage salvateur des biomarqueurs en pathologie mammaire : cas n

    Joyon, Natacha

    Annales de pathologie

    2022  Volume 42, Issue 4, Page(s) 308–312

    Title translation Histoseminar: Saved by a positive staining! About the use of diagnostic biomarkers in breast pathology: Case No. 4.
    MeSH term(s) Biomarkers, Tumor ; Breast ; Breast Neoplasms/diagnosis ; Female ; Humans ; Staining and Labeling
    Chemical Substances Biomarkers, Tumor
    Language French
    Publishing date 2022-01-31
    Publishing country France
    Document type Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2022.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1652: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Dislocation de E-cadhérine dans le carcinome lobulaire invasif du sein.

    Bani, Mohamed Amine / Joyon, Natacha

    Annales de pathologie

    2022  Volume 42, Issue 4, Page(s) 350

    Title translation E-cadherin dislocation in invasive mammary lobular carcinoma.
    MeSH term(s) Breast Neoplasms/pathology ; Cadherins ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Lobular/pathology ; Female ; Humans
    Chemical Substances Cadherins
    Language French
    Publishing date 2022-03-04
    Publishing country France
    Document type Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2022.02.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Uncommon invasive lobular carcinoma with papillary architecture-clinicopathologic and molecular characterization with review of the literature.

    Gessain, Grégoire / Joyon, Natacha / Petit, Thomas / Cotteret, Sophie / Lacroix-Triki, Magali

    Virchows Archiv : an international journal of pathology

    2023  Volume 483, Issue 5, Page(s) 723–729

    Abstract: Breast cancer is the most common malignancy in woman, and its associated mortality is still rising worldwide. Among all the different subtypes of breast cancer, invasive lobular carcinoma (ILC) is the second most frequent. Several histological variants ... ...

    Abstract Breast cancer is the most common malignancy in woman, and its associated mortality is still rising worldwide. Among all the different subtypes of breast cancer, invasive lobular carcinoma (ILC) is the second most frequent. Several histological variants of ILC currently exist such as solid, alveolar, pleomorphic, tubulo-lobular, and mixed types. Recently, a new variant of ILC with a papillary growth pattern has been described. Here, we make a review of the literature and report the sixth case of a woman suffering from this very uncommon variant. Of note, she had a concomitant axillary lymph node metastasis, a manifestation not yet described so far. Molecular analysis showed CDH1 and PIK3CA mutations, along with similar quantitative chromosomal alterations in both primary and metastasis. Because ILC and papillary carcinoma are managed differently, our aim here is to raise awareness among the pathologists to avoid misdiagnosis of this unusual variant and subsequent inappropriate treatment.
    MeSH term(s) Female ; Humans ; Carcinoma, Lobular/diagnosis ; Carcinoma, Lobular/genetics ; Carcinoma, Lobular/pathology ; Breast Neoplasms/pathology ; Lymphatic Metastasis ; Carcinoma, Ductal, Breast/pathology
    Language English
    Publishing date 2023-03-16
    Publishing country Germany
    Document type Review ; Journal Article
    ZDB-ID 1184867-4
    ISSN 1432-2307 ; 0945-6317
    ISSN (online) 1432-2307
    ISSN 0945-6317
    DOI 10.1007/s00428-023-03526-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud III Zs.10: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Une autre bactérie gastrique à connaître.

    Joyon, Natacha / Burtin, Pascal / Scoazec, Jean-Yves

    Annales de pathologie

    2020  Volume 40, Issue 1, Page(s) 31–34

    Title translation Another gastric bacteria to know.
    MeSH term(s) Adenocarcinoma/secondary ; Adenocarcinoma/therapy ; Aged ; Bezoars/diagnosis ; Chronic Disease ; Clostridium/isolation & purification ; Clostridium Infections/microbiology ; Gastritis/microbiology ; Gastritis/pathology ; Humans ; Lymphadenopathy/diagnostic imaging ; Male ; Mediastinal Diseases/diagnostic imaging ; Multiple Pulmonary Nodules/pathology ; Rectal Neoplasms/therapy
    Language French
    Publishing date 2020-01-03
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2019.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1652: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Diagnostic Challenges and Pitfalls of Mammary Pleomorphic Adenoma Illustrated by a Case Report.

    Joyon, Natacha / Mathieu, Marie-Christine / Rouleau, Etienne / Roulot-Paumelle, Aurélie / Scoazec, Jean-Yves / Suciu, Voichita

    International journal of surgical pathology

    2022  Volume 31, Issue 4, Page(s) 472–477

    Abstract: Mammary pleomorphic adenoma is a biphasic tumor, characterized by epithelial-myoepithelial components with myxochondroid stroma, resembling the prototypic pleomorphic adenoma of the salivary glands. We report the multiple diagnostic pitfalls raised by a ... ...

    Abstract Mammary pleomorphic adenoma is a biphasic tumor, characterized by epithelial-myoepithelial components with myxochondroid stroma, resembling the prototypic pleomorphic adenoma of the salivary glands. We report the multiple diagnostic pitfalls raised by a mammary pleomorphic adenoma, initially diagnosed as mucinous carcinoma on fine-needle aspiration (FNA) cytology and invasive carcinoma on needle core biopsy. The final diagnosis was made on the surgical specimen. As the term "pleomorphic" suggests, this tumor can present various phenotypes, some of which might be misleading on both FNA cytology or needle core biopsy. Rearrangements in
    MeSH term(s) Humans ; Adenoma, Pleomorphic/diagnosis ; Adenoma, Pleomorphic/pathology ; Salivary Glands/pathology ; Carcinoma/pathology ; Biopsy, Fine-Needle ; Breast/surgery ; Breast/pathology ; Salivary Gland Neoplasms/pathology
    Language English
    Publishing date 2022-05-29
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1336393-1
    ISSN 1940-2465 ; 1066-8969
    ISSN (online) 1940-2465
    ISSN 1066-8969
    DOI 10.1177/10668969221102552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4500: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Un nodule de la paroi rectale.

    Joyon, Natacha / Tran, Suzanne / Sourrouille, Isabelle / Scoazec, Jean-Yves

    Annales de pathologie

    2020  Volume 40, Issue 3, Page(s) 238–242

    Title translation A nodule of the rectal wall.
    MeSH term(s) Aged ; Choristoma/diagnosis ; Choristoma/pathology ; Diagnosis, Differential ; Histocytochemistry/methods ; Humans ; Immunohistochemistry/methods ; Intestinal Mucosa/pathology ; Male ; Prostate ; Rectal Neoplasms/diagnosis ; Rectal Neoplasms/pathology ; Rectum/pathology
    Language French
    Publishing date 2020-04-08
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2020.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1652: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Multifocal in situ mantle cell neoplasia of the ileocecal region: a case report with simultaneous nodal and extranodal involvement.

    Joyon, Natacha / Kanaan, Christina / Cotteret, Sophie / Sourrouille, Isabelle / Scoazec, Jean-Yves / Dartigues, Peggy

    Virchows Archiv : an international journal of pathology

    2021  Volume 479, Issue 5, Page(s) 1037–1040

    Abstract: In situ mantle cell neoplasia (ISMCN) is a rare entity of disputed clinical significance. We report an additional case, unusual by its presentation in the large intestine and its multifocal involvement of several nodal and extranodal sites. The diagnosis ...

    Abstract In situ mantle cell neoplasia (ISMCN) is a rare entity of disputed clinical significance. We report an additional case, unusual by its presentation in the large intestine and its multifocal involvement of several nodal and extranodal sites. The diagnosis was made in a 46-year-old male patient from a surgical specimen resected for cecal adenocarcinoma. Gross examination showed multiple small polypoid lesions surrounding the ileocecal valve, corresponding to lymphoid aggregates with hyperplastic follicles. Numerous cyclin D1/SOX11+ lymphoid cells, harboring the t(11;14)(q13;q32) translocation, were present in the inner layers of mantle zones. The same lesions were found in the ileum, the appendix, and the regional lymph nodes. The final diagnosis was multifocal ISMCN of the ileocecal region, with both nodal and extra-nodal involvement. A simple surveillance was decided. Our observation expands the clinical spectrum of the disease and underlines the necessity to closely examine even normal-appearing reactive lymphoid tissues.
    MeSH term(s) Adenocarcinoma/chemistry ; Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/genetics ; Biopsy ; Cecal Neoplasms/chemistry ; Cecal Neoplasms/genetics ; Cecal Neoplasms/pathology ; Diagnosis, Differential ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Lymphoid Tissue/chemistry ; Lymphoid Tissue/pathology ; Lymphoma, Mantle-Cell/chemistry ; Lymphoma, Mantle-Cell/genetics ; Lymphoma, Mantle-Cell/pathology ; Male ; Middle Aged ; Neoplasms, Multiple Primary ; Predictive Value of Tests ; Translocation, Genetic
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2021-03-01
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 1184867-4
    ISSN 1432-2307 ; 0945-6317
    ISSN (online) 1432-2307
    ISSN 0945-6317
    DOI 10.1007/s00428-021-03065-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud III Zs.10: Show issues Location:
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  9. Article ; Online: Malignant Adenomyoepithelioma of the Breast: An Unexpected Malignancy in a Lynch Syndrome Patient.

    Joyon, Natacha / Guillaume, Zoe / Ouafi, Lamia / Cotteret, Sophie / Rouleau, Etienne / Caron, Olivier / Goldbarg, Veronica / Lacroix-Triki, Magali

    International journal of surgical pathology

    2022  Volume 31, Issue 5, Page(s) 572–575

    MeSH term(s) Humans ; Female ; Adenomyoepithelioma/diagnosis ; Adenomyoepithelioma/surgery ; Adenomyoepithelioma/pathology ; Colorectal Neoplasms, Hereditary Nonpolyposis/complications ; Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Breast/surgery ; Breast/pathology ; Breast Neoplasms
    Language English
    Publishing date 2022-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1336393-1
    ISSN 1940-2465 ; 1066-8969
    ISSN (online) 1940-2465
    ISSN 1066-8969
    DOI 10.1177/10668969221105623
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Pullulation bactérienne gastrique : une observation histologique inhabituelle, à ne pas méconnaître.

    Langlois, Valentine / Joyon, Natacha / Farah, Rita Bou / Chachaty, Elisabeth / Scoazec, Jean-Yves

    Annales de pathologie

    2020  Volume 41, Issue 2, Page(s) 196–200

    Abstract: Gastric bacterial overgrowth is a rare situation, which may be associated with short- and long-term complications. It must be known from pathologists, since it might be detected incidentally at histological examination of gastric biopsies. We report here ...

    Title translation Gastric bacterial overgrowth: An unusual histological observation, not to be overlooked.
    Abstract Gastric bacterial overgrowth is a rare situation, which may be associated with short- and long-term complications. It must be known from pathologists, since it might be detected incidentally at histological examination of gastric biopsies. We report here the case of a 74-year old woman, obese, without significant medical history, apart from a gastro-esophageal reflux treated by the long-term administration of proton pump inhibitors (PPI). In this patient, gastric bacterial overgrowth was detected at histological examination of gastric biopsies performed after colectomy for left colon adenocarcinoma. Large clusters of small, round, "coccoid" bacteria were present in the gastric mucus. Their characteristics were suggestive of enterobacteria. Bacterial proliferation was associated with severe and diffuse lesions of active gastritis. The course was rapidly unfavorable, and the patient rapidly deceased with multiple infections and multi-organ failure. In our observation, the pathogenesis of gastric bacterial overgrowth was probably multifactorial. It might have been facilitated by long-term PPI treatment and obesity, which are known risk factors, and promoted, in the post-operative setting, by multiple infections and immune failure. Our observation underlines that gastric bacterial overgrowth might be associated with severe gastritis, which might justify antibiotherapy. Other consequences of prolonged gastric dysbiosis cannot be excluded, such as the promotion of neoplastic lesions.
    MeSH term(s) Aged ; Female ; Gastritis ; Humans ; Proton Pump Inhibitors/adverse effects ; Risk Factors
    Chemical Substances Proton Pump Inhibitors
    Language French
    Publishing date 2020-12-14
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2020.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    ab Jg. 2022: Lesesaal (EG)

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