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Book ; Online: Making the Palace Machine Work : Mobilizing People, Objects, and Nature in the Qing Empire

Siebert, Martina / Jun Chen, Kai / Ko, Dorothy

2021

Keywords	Museology & heritage studies ; Asian history ; China, Qing Court, Material culture ; Imperial Household Department
Size	1 electronic resource (347 pages)
Publisher	Amsterdam University Press
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021050933
ISBN	9789048553228 ; 9048553229
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: The Condorcet Jury Theorem with Information Acquisition

Jun Chen

Games, Vol 12, Iss 79, p

2021 Volume 79

Abstract: We analyze a committee decision in which individuals with common preferences are uncertain which of two alternatives is better for them. Members can acquire costly information. Private signals and information choice are both continuous. As is consistent ... ...

Abstract	We analyze a committee decision in which individuals with common preferences are uncertain which of two alternatives is better for them. Members can acquire costly information. Private signals and information choice are both continuous. As is consistent with Down’s rational ignorance hypothesis, each member acquires less information in a larger committee and tends to acquire zero information when the committee size goes to infinity. However, with more members, a larger committee can gather more aggregate information in equilibrium. The aggregate information is infinite with the size going to infinity if and only if marginal cost at “zero information acquisition” is zero. When the marginal cost at “zero information acquisition” is positive, the probability of making an appropriate decision tends to be less than one.
Keywords	information acquisition ; the Condorcet Jury Theorem ; jury size ; committee decision ; Technology ; T ; Social Sciences ; H
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Diversification or specialization

Jun Chen / Guangzhen Guo

Journal of Innovation & Knowledge, Vol 8, Iss 1, Pp 100306- (2023)

Measuring the impact of high-speed rail connection on technological diversity in China

2023

Abstract: Technological diversification and specialization have important roles in explaining volatility, innovation, income inequality, exports, and related concerns; however, the relationships between transportation improvement and technological diversification ... ...

Abstract	Technological diversification and specialization have important roles in explaining volatility, innovation, income inequality, exports, and related concerns; however, the relationships between transportation improvement and technological diversification and specialization remains unexplored. Using Chinese city-level panel data, we investigate the impact of China's high-speed rail (HSR) connection on technological diversity using the difference-in-differences method and instrumental variable regressions. The results demonstrate that HSR connection leads to reductions in technological diversity, particularly in core cities, cities along the four longest HSR lines, and cities that were initially diversified. The findings indicate that HSR connection is conducive to technological specialization rather than diversification, offering new insights for understanding the relationship between transportation improvement and innovation and determining that HSR connection spurs intra-industry knowledge spillovers more than inter-industry knowledge spillovers.
Keywords	Technological diversification ; Technological specialization ; High-speed rail ; Innovation ; Knowledge spillovers ; History of scholarship and learning. The humanities ; AZ20-999 ; Social sciences (General) ; H1-99
Subject code	339 ; 650
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A study of the mechanism for intergenerational transmission of gender roles in single-parent families

I-Jun Chen / Zisong Chen

Heliyon, Vol 9, Iss 12, Pp e22952- (2023)

2023

Abstract: The divorce rate in China is rising yearly, and the concept of marriage is changing, triggering many social topics related to single parents. Among them, gender-awareness education for children in single-parent families is particularly worthy of ... ...

Abstract	The divorce rate in China is rising yearly, and the concept of marriage is changing, triggering many social topics related to single parents. Among them, gender-awareness education for children in single-parent families is particularly worthy of attention, as there has been insufficient exploration of how parents transfer their gender role concepts to their children. This study conducted in-depth interviews with 58 single parents and children from 29 families in Suzhou and constructed the mechanism for intergenerational transmission of gender roles in single-parent families based on grounded theory. It found that single parents' gender stereotypes, the starting point of the intergenerational transmission mechanism, have been diluted. It affords them a more enlightened attitude towards child-rearing style, and they expect more equality in the gender role of their offspring. However, in some parents' actual parenting process, when the children's sexualization behaviours exceed their acceptance range, they will communicate with children in an authoritative and didactic way to “correct” the children's behaviour. In addition to direct verbal instruction, parents' expectations of their children's gender roles will be implicitly conveyed through various parent-child interactions in daily life to affect the formation of their children's gender roles. In the intergenerational transmission of gender roles, external people (such as grandparents, teachers and peer groups) have horizontal socialisation effects on children to modify or strengthen the results of gender education from their parents. Under the comprehensive influence of the above factors, the children's gender roles are finally determined. These studies expand previous theories and studies and have significant theoretical and practical implications.
Keywords	Gender roles ; Grounded theory ; Intergenerational transmission ; Single-parent family ; Transmission mechanism ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	370
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: A Review of the Pharmacokinetic Characteristics of Immune Checkpoint Inhibitors and Their Clinical Impact Factors.

Liu, Jun-Chen / Yu, Hong-Jing

Pharmacogenomics and personalized medicine

2023 Volume 16, Page(s) 29–36

Abstract: Immune checkpoint inhibitors (ICIs) have been shown to be significant in improving the overall survival rate in certain malignancies with poor prognoses. However, only 20-40% of patients achieve long-term benefits, highlighting the relevance of the ... ...

Abstract	Immune checkpoint inhibitors (ICIs) have been shown to be significant in improving the overall survival rate in certain malignancies with poor prognoses. However, only 20-40% of patients achieve long-term benefits, highlighting the relevance of the factors that influence the treatment, which can help clinicians improve their results and guide the development of new immune checkpoint therapies. In this study, the current pharmacokinetic aspects associated with the ICIs and the factors influencing clinical efficacy were characterised, including in terms of drug metabolism, drug clearance, hormonal effects and immunosuppressive effects.
Language	English
Publishing date	2023-01-20
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2508173-1
ISSN	1178-7066
ISSN	1178-7066
DOI	10.2147/PGPM.S391756
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Metal–Organic Cages

Shangjun Chen / Li-Jun Chen

Chemistry, Vol 4, Iss 36, Pp 494-

Applications in Organic Reactions

2022 Volume 519

Abstract: Supramolecular metal–organic cages, a class of molecular containers formed via coordination-driven self-assembly, have attracted sustained attention for their applications in catalysis, due to their structural aesthetics and unique properties. Their ... ...

Abstract	Supramolecular metal–organic cages, a class of molecular containers formed via coordination-driven self-assembly, have attracted sustained attention for their applications in catalysis, due to their structural aesthetics and unique properties. Their inherent confined cavity is considered to be analogous to the binding pocket of enzymes, and the facile tunability of building blocks offers a diverse platform for enzyme mimics to promote organic reactions. This minireview covers the recent progress of supramolecular metal–organic coordination cages for boosting organic reactions as reaction vessels or catalysts. The developments in the utilizations of the metal–organic cages for accelerating the organic reactions, improving the selectivity of the reactions are summarized. In addition, recent developments and successes in tandem or cascade reactions promoted by supramolecular metal–organic cages are discussed.
Keywords	catalysis ; green chemistry ; metal–organic cages ; organic reactions ; supramolecular chemistry ; tandem reactions ; Chemistry ; QD1-999
Subject code	540
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Spatiotemporal Variability in Water-Use Efficiency in Tianshan Mountains (Xinjiang, China) and the Influencing Factors

Jun Chen / Liguo Cao

Sustainability, Vol 14, Iss 8191, p

2022 Volume 8191

Abstract: Water-use efficiency (WUE) is a crucial physiological index in carbon–water interactions and is defined as the ratio of vegetation productivity to water loss. The variation in climatic variables and drought have the most significant effects on WUE and ... ...

Abstract	Water-use efficiency (WUE) is a crucial physiological index in carbon–water interactions and is defined as the ratio of vegetation productivity to water loss. The variation in climatic variables and drought have the most significant effects on WUE and evapotranspiration (ET). Nevertheless, how WUE varies with climate factors and drought processes in the Tianshan Mountains (TMS) is still poorly understood. In the present work, we analyzed the spatiotemporal variations in WUE, and investigated the correlations between WUE, climate factors, and drought, in the study area. The results showed that, in the TMS during 2000–2020, annual net primary productivity (NPP) ranged from 147.9 to 189.4 gC·m −2 , annual ET was in the range of 212.5–285.8 mm, and annual WUE ranged from 0.66 to 0.78 gC·kg −1 ·H 2 O. Both NPP and ET exhibited an increasing trend with some fluctuation, whereas WUE showed the opposite tendency during the study period. The obtained results demonstrated that the decrease in WUE was primarily because of the increase in ET. There were obvious differences in WUE, under different land-use types, caused by NPP and ET. However, the interannual variation in WUE showed small fluctuations and the dynamic process of WUE in each land-use type showed good consistency. Temperature and wind speed had a positive influence on WUE in the middle and eastern regions of the TMS. Precipitation also played a mainly positive role in enhancing WUE, especially on the northern slope of the TMS. There was strong spatial heterogeneity of the correlation coefficient (0.68, p < 0.05) between WUE and the temperature vegetation drought index (TVDI). Moreover, the slopes of WUE and TVDI showed good consistency in terms of spatial distribution, suggesting that drought had a significant impact on ecosystem WUE. This work will enhance the understanding of WUE variation, and provide scientific evidence for water resource management and sustainable utilization in the study area.
Keywords	water-use efficiency ; climate factor ; spatiotemporal variation ; drought ; Tianshan Mountains ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	333
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effects of Extracorporeal Shock Wave Combined with Vivaphototherapy on Blood Perfusion, Inflammatory Response, and Prognosis in Burn Patients

Jun Chen / Jianwei Nie

Computational and Mathematical Methods in Medicine, Vol

2022 Volume 2022

Abstract: Objective. To investigate the effect of extracorporeal shock wave treatment (ESWT) combined with water-filtered infrared-A (wIRA) therapy on pain, blood perfusion, and inflammatory response in burn patients. Methods. A total of 120 burn patients treated ... ...

Abstract	Objective. To investigate the effect of extracorporeal shock wave treatment (ESWT) combined with water-filtered infrared-A (wIRA) therapy on pain, blood perfusion, and inflammatory response in burn patients. Methods. A total of 120 burn patients treated in our hospital from May 2019 to June 2021 were selected and randomly divided into observation group (n=60) and control group (n=60). The control group was treated with wIRA, and the observation group was treated with ESWT combined with wIRA. The hospitalization conditions of the two groups were observed; the visual analogue scale (VAS) was used to evaluate the pain on the 1st, 7th, and 14th days of treatment in the two groups; the blood perfusion was compared between the two groups; the levels of cerebral neuropeptide (NPY), 5-serotonin (5-HT), prostaglandin E2 (PGE2), C-reactive protein (CRP), interleukin-10 (IL-10), tumor necrosis factor-α (TNF-α), serum intercellular adhesion molecule-1 (sICAM-1), soluble-triggering receptor expressed myeloidcells-1 (sTREM-1), and soluble hemoglobin scavenger receptor (sCD163) were measured. Modified Vancouver Scar Scale (mVSS) was used to evaluate the wound scar at 3 and 6 months after the end of treatment. Results. The wound healing rate in the observation group was significantly higher than that in the control group, and the wound healing time and hospitalization time were significantly shorter than that in the control group (P<0.05). On the 7th and 14th days of treatment, the VAS scores of the observation group were significantly lower than those of the control group (P<0.05). On 1st, 7th, and 14th days of treatment, the blood perfusion volume in the observation group was significantly higher than that in the control group (P<0.05). The scar scores in the observation group at 3 months and 6 months after treatment were significantly lower than those in the control group (P<0.05). After treatment, the levels of NPY, 5-HT, PGE2, CRP, IL-10, TNF-α, sICAM-1, sTREM-1, and sCD163 in the observation group were ...
Keywords	Computer applications to medicine. Medical informatics ; R858-859.7
Subject code	630
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Flower Bud from the Lower Cretaceous of China

Li-Jun Chen / Xin Wang

Biology, Vol 11, Iss 1598, p

2022 Volume 1598

Abstract: Background: Although various angiosperms (including their flowers) have been reported from the Yixian Formation (Lower Cretaceous) of China, which is famous worldwide for its fossils of early angiosperms, no flower bud has hitherto been seen in the Early ...

Abstract	Background: Although various angiosperms (including their flowers) have been reported from the Yixian Formation (Lower Cretaceous) of China, which is famous worldwide for its fossils of early angiosperms, no flower bud has hitherto been seen in the Early Cretaceous. Such a lack of examples hinders our understanding of the evolution of flowers. Methods: The specimen studied in the present paper was collected from an outcrop of the Yixian Formation (the Barremian-Aptian, Lower Cretaceous) of Dawangzhangzi in Lingyuan, Liaoning, China. The specimen was photographed using a Nikon D200 digital camera, its details were observed and photographed using a Nikon SMZ1500 stereomicroscope, and some of its details were observed using a Leo 1530 VP SEM. Results: We report a fossilized flower bud, Archaebuda lingyuanensis gen. et sp. nov, from the Yixian Formation of China. The debut of Archaebuda in the Yixian Formation provides first-hand material for debate on the early evolution of angiosperm flowers and underscores the great diversity of angiosperms in the Yixian Formation.
Keywords	fossil ; Lower Cretaceous ; China ; angiosperms ; flower ; bud ; Biology (General) ; QH301-705.5
Subject code	950
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Fibroblast growth factor 21

Shuo Li / Tiande Zou / Jun Chen / Jiaming Li / Jinming You

Genes and Diseases, Vol 11, Iss 3, Pp 101064- (2024)

An emerging pleiotropic regulator of lipid metabolism and the metabolic network

2024

Abstract: Fibroblast growth factor 21 (FGF21) was originally identified as an important metabolic regulator which plays a crucial physiological role in regulating a variety of metabolic parameters through the metabolic network. As a novel multifunctional endocrine ...

Abstract	Fibroblast growth factor 21 (FGF21) was originally identified as an important metabolic regulator which plays a crucial physiological role in regulating a variety of metabolic parameters through the metabolic network. As a novel multifunctional endocrine growth factor, the role of FGF21 in the metabolic network warrants extensive exploration. This insight was obtained from the observation that the FGF21-dependent mechanism that regulates lipid metabolism, glycogen transformation, and biological effectiveness occurs through the coordinated participation of the liver, adipose tissue, central nervous system, and sympathetic nerves. This review focuses on the role of FGF21-uncoupling protein 1 (UCP1) signaling in lipid metabolism and how FGF21 alleviates non-alcoholic fatty liver disease (NAFLD). Additionally, this review reveals the mechanism by which FGF21 governs glucolipid metabolism. Recent research on the role of FGF21 in the metabolic network has mostly focused on the crucial pathway of glucolipid metabolism. FGF21 has been shown to have multiple regulatory roles in the metabolic network. Since an adequate understanding of the concrete regulatory pathways of FGF21 in the metabolic network has not been attained, this review sheds new light on the metabolic mechanisms of FGF21, explores how FGF21 engages different tissues and organs, and lays a theoretical foundation for future in-depth research on FGF21-targeted treatment of metabolic diseases.
Keywords	Adipose ; FGF21 ; Insulin homeostasis ; Lipid metabolism ; Liver ; Metabolic network ; Medicine (General) ; R5-920 ; Genetics ; QH426-470
Subject code	570
Language	English
Publishing date	2024-05-01T00:00:00Z
Publisher	KeAi Communications Co., Ltd.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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