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  1. Article: Risk Factors that Predict Levothyroxine Medication after Thyroid Lobectomy.

    Song, H S / Kim, C J / Lee, S / Bae, J S / Jung, C K / Jang, J

    Acta endocrinologica (Bucharest, Romania : 2005)

    2021  Volume 16, Issue 4, Page(s) 454–461

    Abstract: Context and objective: The risk of needing lifelong thyroid hormone supplementation is an important factor affecting treatment decisions for both patients and clinicians ahead thyroid lobectomy. The purposes of this study were to assess the predictive ... ...

    Abstract Context and objective: The risk of needing lifelong thyroid hormone supplementation is an important factor affecting treatment decisions for both patients and clinicians ahead thyroid lobectomy. The purposes of this study were to assess the predictive factors of levothyroxine medication after thyroid lobectomy.
    Methods: We retrospectively reviewed 252 patients who had undergone lobectomy for benign thyroid nodules between April 2009 and April 2017. We conducted two independent analyses: patients who started taking levothyroxine after surgery were compared with those who did not, and patients who did not need levothyroxine at last follow-up were compared with those who required continued treatment. We investigated the correlations of patient clinicopathological characteristics and levothyroxine medication after lobectomy.
    Results: Ninety-eight patients started levothyroxine after surgery. Of these, 34 patients successfully ceased medication and 64 patients continued treatment as of their last follow-up. In multivariate analysis, older age and preoperative TSH ≥2.0mIU/L were associated with levothyroxine initiation after surgery. In terms of continuity of levothyroxine, both older age and TSH ≥ 3.0mIU/L showed a significant correlation with continuous medication. We created a risk-scoring system to predict likelihood of starting and maintaining levothyroxine using the two significant factors in each comparison. A risk score of 3 or more indicated an increased risk of starting levothyroxine (specificity = 81.8%; sensitivity = 48.0%). A risk score of 3 or more indicated increased risk of continuous medication, (specificity = 94.2%; sensitivity = 35.9%).
    Conclusions: Greater age and higher preoperative TSH levels correlated with initiation and continuity of levothyroxine medication after lobectomy.
    Language English
    Publishing date 2021-04-09
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 1433812-9
    ISSN 1843-066X ; 1841-0987
    ISSN (online) 1843-066X
    ISSN 1841-0987
    DOI 10.4183/aeb.2020.454
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    Zs.A 6261: Show issues Location:
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  2. Article ; Online: Safety and efficacy of trastuzumab biosimilar plus irinotecan or gemcitabine in patients with previously treated HER2 (ERBB2)-positive non-breast/non-gastric solid tumors: a phase II basket trial with circulating tumor DNA analysis.

    Hyung, J / Lee, J Y / Kim, J E / Yoon, S / Yoo, C / Hong, Y S / Jeong, J H / Kim, T W / Jeon, S / Jun, H R / Jung, C K / Jang, J P / Kim, J / Chun, S M / Ahn, J H

    ESMO open

    2023  Volume 8, Issue 3, Page(s) 101583

    Abstract: Background: Human epidermal growth factor receptor 2 (HER2) (ERBB2)-directed agents are standard treatments for patients with HER2-positive breast and gastric cancer. Herein, we report the results of an open-label, single-center, phase II basket trial ... ...

    Abstract Background: Human epidermal growth factor receptor 2 (HER2) (ERBB2)-directed agents are standard treatments for patients with HER2-positive breast and gastric cancer. Herein, we report the results of an open-label, single-center, phase II basket trial to investigate the efficacy and safety of trastuzumab biosimilar (Samfenet®) plus treatment of physician's choice for patients with previously treated HER2-positive advanced solid tumors, along with biomarker analysis employing circulating tumor DNA (ctDNA) sequencing.
    Methods: Patients with HER2-positive unresectable or metastatic non-breast, non-gastric solid tumors who failed at least one prior treatment were included in this study conducted at Asan Medical Center, Seoul, Korea. Patients received trastuzumab combined with irinotecan or gemcitabine at the treating physicians' discretion. The primary endpoint was the objective response rate as per RECIST version 1.1. Plasma samples were collected at baseline and at the time of disease progression for ctDNA analysis.
    Results: Twenty-three patients were screened from 31 December 2019 to 17 September 2021, and 20 were enrolled in this study. Their median age was 64 years (30-84 years), and 13 patients (65.0%) were male. The most common primary tumor was hepatobiliary cancer (seven patients, 35.0%), followed by colorectal cancer (six patients, 30.0%). Among 18 patients with an available response evaluation, the objective response rate was 11.1% (95% confidence interval 3.1% to 32.8%). ERBB2 amplification was detected from ctDNA analysis of baseline plasma samples in 85% of patients (n = 17), and the ERBB2 copy number from ctDNA analysis showed a significant correlation with the results from tissue sequencing. Among 16 patients with post-progression ctDNA analysis, 7 (43.8%) developed new alterations. None of the patients discontinued the study due to adverse events.
    Conclusions: Trastuzumab plus irinotecan or gemcitabine was safe and feasible for patients with previously treated HER2-positive advanced solid tumors with modest efficacy outcomes, and ctDNA analysis was useful for detecting HER2 amplification.
    MeSH term(s) Female ; Humans ; Male ; Middle Aged ; Biosimilar Pharmaceuticals/adverse effects ; Circulating Tumor DNA/genetics ; Gemcitabine ; Irinotecan ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/genetics ; Trastuzumab/adverse effects ; Adult ; Aged ; Aged, 80 and over
    Chemical Substances Biosimilar Pharmaceuticals ; Circulating Tumor DNA ; ERBB2 protein, human (EC 2.7.10.1) ; Gemcitabine ; Irinotecan (7673326042) ; Trastuzumab (P188ANX8CK)
    Language English
    Publishing date 2023-06-14
    Publishing country England
    Document type Clinical Trial, Phase II ; Journal Article
    ISSN 2059-7029
    ISSN (online) 2059-7029
    DOI 10.1016/j.esmoop.2023.101583
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  3. Article ; Online: Thyroid FNA cytology in Asian practice-Active surveillance for indeterminate thyroid nodules reduces overtreatment of thyroid carcinomas.

    Kakudo, K / Higuchi, M / Hirokawa, M / Satoh, S / Jung, C K / Bychkov, A

    Cytopathology : official journal of the British Society for Clinical Cytology

    2017  Volume 28, Issue 6, Page(s) 455–466

    Abstract: Although Asian thyroid practices have implemented the American Thyroid Association guidelines, significant deviations in actual risk of malignancy (ROM) have been reported. With review of the literature from Asia, the authors examine the underlining ... ...

    Abstract Although Asian thyroid practices have implemented the American Thyroid Association guidelines, significant deviations in actual risk of malignancy (ROM) have been reported. With review of the literature from Asia, the authors examine the underlining reasons for actual ROMs reported in Asia being so different from western practice based on the author's perspective. Although the most popular diagnostic system for thyroid cytology used in Asian countries is the Bethesda system, the Japan Thyroid Association published clinical guidelines, including a national reporting system for thyroid cytology, to adapt conservative clinical management (active surveillance and strict triage patients for surgery) for low-risk thyroid carcinomas. As less aggressive clinical management is favoured in Asian societies, strict triage of patients with indeterminate thyroid nodules for surgery is usually applied, which ultimately reduces overtreatment of indolent thyroid tumours. As a result, low resection rates and high ROMs for indeterminate nodules were achieved in Asian practices using the same Bethesda system. Recently, borderline thyroid tumours were introduced in the thyroid tumour classification and significant decreases in ROMs have been reported in the indeterminate categories in western practice. However, ROM of indeterminate nodules remained high in Asian practice even after borderline tumours were deemed benign. These results suggested that the diagnostic threshold of papillary thyroid carcinoma-type nuclear features varied among practices (stricter in Asia than in western practice), and diagnostic surgery was not performed for a significant number of indeterminate nodules with benign clinical features in Asian practice, resulting in low rates of borderline tumours in surgically-treated patients.
    MeSH term(s) Biopsy, Fine-Needle/methods ; Carcinoma, Papillary/drug therapy ; Cytodiagnosis ; Humans ; Medical Overuse/prevention & control ; Thyroid Cancer, Papillary ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/drug therapy ; Thyroid Neoplasms/pathology ; Thyroid Nodule/pathology
    Language English
    Publishing date 2017-11-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.12491
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  4. Article ; Online: An unusual presentation of aggressive epithelial-myoepithelial carcinoma of the nasal cavity with high-grade histology.

    Park, J-O / Jung, C-K / Sun, D-I / Kim, M-S

    The Journal of laryngology and otology

    2011  Volume 125, Issue 12, Page(s) 1286–1289

    Abstract: Background: Epithelial-myoepithelial carcinoma is an uncommon, low-grade carcinoma that generally occurs in the salivary glands. A few cases of epithelial-myoepithelial carcinoma arising in the nasal cavity have been reported. We describe a unique case ... ...

    Abstract Background: Epithelial-myoepithelial carcinoma is an uncommon, low-grade carcinoma that generally occurs in the salivary glands. A few cases of epithelial-myoepithelial carcinoma arising in the nasal cavity have been reported. We describe a unique case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity.
    Case report: A 36-year-old woman presented with a mass in her left nasal cavity. Histopathological evaluation revealed it to be an epithelial-myoepithelial carcinoma with overt nuclear atypia, frequent mitoses and necrosis. The tumour recurred in the contralateral nasal cavity 15 months following primary excision. Medial maxillectomy and radiation therapy were performed. Seven-month follow up revealed extensive bone metastases.
    Conclusion: We report a rare case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity, with high-grade histology.
    MeSH term(s) Adult ; Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/secondary ; Carcinoma/diagnostic imaging ; Carcinoma/pathology ; Carcinoma/surgery ; Female ; Histological Techniques ; Humans ; Multimodal Imaging ; Myoepithelioma/diagnostic imaging ; Myoepithelioma/pathology ; Myoepithelioma/surgery ; Nasal Cavity/pathology ; Nasal Cavity/surgery ; Nose Neoplasms/diagnostic imaging ; Nose Neoplasms/pathology ; Nose Neoplasms/surgery ; Positron-Emission Tomography ; Tomography, X-Ray Computed
    Language English
    Publishing date 2011-12
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/S0022215111002222
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  5. Article: A study on the characteristics of TiOxNy thin films with various nitrogen flow rate by PECVD method

    Cho, S.-J / Jung, C.-K / Boo, J.-H

    Current applied physics. 2012 Dec. 20, v. 12S4

    2012  

    Abstract: TiOxNy thin films were deposited on Si(100) substrates at 500 °C using RF PECVD system. Titanium isopropoxide was used as precursor with different nitrogen flow rate to control nitrogen contents in the films. Changes of chemical states of constituent ... ...

    Abstract TiOxNy thin films were deposited on Si(100) substrates at 500 °C using RF PECVD system. Titanium isopropoxide was used as precursor with different nitrogen flow rate to control nitrogen contents in the films. Changes of chemical states of constituent elements in the deposited films were examined by X-ray photoelectron spectroscopy (XPS) analysis. The data showed that the nitrogen content ratio was increased with increasing nitrogen flow rate, also the binding energy shift toward high energy side. The characteristics of film growth orientation and structure as well as morphology were also analyzed by X-ray diffraction (XRD), transmission electron diffraction (TED), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). The film growth orientation, structure, and morphology were changed by increasing nitrogen flow rate. Nano-indentation experiments showed strong dependency on the composition of nitrogen and nano-structure in the hardness range of between 8 and 16 GPa.
    Keywords X-ray diffraction ; X-ray photoelectron spectroscopy ; energy ; hardness ; nitrogen ; nitrogen content ; scanning electron microscopy ; silicon ; titanium ; transmission electron microscopy
    Language English
    Dates of publication 2012-1220
    Size p. S29-S34.
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 1567-1739
    DOI 10.1016/j.cap.2012.05.037
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: The distance between the carina and the distal margin of the right upper lobe orifice measured by computerised tomography as a guide to right-sided double-lumen endobronchial tube use.

    Kim, J H / Park, S H / Han, S H / Nahm, F S / Jung, C K / Kim, K M

    Anaesthesia

    2013  Volume 68, Issue 7, Page(s) 700–705

    Abstract: Our hypothesis was that the incidence of malposition of a right-sided double-lumen endobronchial tube and right upper lobe collapse may increase when the distance between the carina and the distal margin of the right upper lobe orifice is less than 23 mm, ...

    Abstract Our hypothesis was that the incidence of malposition of a right-sided double-lumen endobronchial tube and right upper lobe collapse may increase when the distance between the carina and the distal margin of the right upper lobe orifice is less than 23 mm, measured from a computerised tomography scan. A total of 76 patients undergoing left-sided thoracic surgery were enrolled. Patients with a measured distance of <23 mm (n=38) were compared with age-, sex- and body mass index-matched patients with a distance≥23 mm (n=38). Right-sided double-lumen endobronchial tubes were used universally. We monitored endobronchial tube malposition and incidence of right upper lobe collapse throughout surgery. There was a significantly higher incidence of bronchial cuff herniation in patients with a distance<23 mm in both the supine position and the lateral decubitus position (p<0.001). The incidence of intra-operative malposition in the <23 mm group was also significantly higher than in the ≥23 mm group (31 (82%) vs 8 (21%), respectively, p<0.001). Right upper lobe collapse was detected postoperatively in five patients (13%) in the distance<23 mm group, compared to none in the ≥23 mm group. We recommend that the distance between the carina and the distal margin of the right upper lobe bronchus should be routinely measured on the pre-operative computerised tomography scan, and if it is <23 mm, consideration should be given to using a left-sided endobronchial double-lumen tube in preference to a right-sided one.
    MeSH term(s) Anesthesia, General ; Bronchoscopy ; Female ; Humans ; Intraoperative Complications/prevention & control ; Intubation, Intratracheal/instrumentation ; Intubation, Intratracheal/methods ; Lung/anatomy & histology ; Lung/diagnostic imaging ; Lung/surgery ; Male ; Medical Errors/prevention & control ; Middle Aged ; Pulmonary Atelectasis/prevention & control ; Sample Size ; Supine Position ; Thoracic Surgical Procedures ; Tomography, X-Ray Computed
    Language English
    Publishing date 2013-05-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.12208
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    Zs.A 388: Show issues Location:
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  7. Article: Decentration and tilt: silicone multifocal versus acrylic soft intraocular lenses.

    Jung, C K / Chung, S K / Baek, N H

    Journal of cataract and refractive surgery

    2000  Volume 26, Issue 4, Page(s) 582–585

    Abstract: Purpose: To compare differences in decentration and tilt between a silicone multifocal and an acrylic intraocular lens (IOL) by evaluating postoperative changes.: Setting: Department of Ophthalmology, College of Medicine, The Catholic University of ... ...

    Abstract Purpose: To compare differences in decentration and tilt between a silicone multifocal and an acrylic intraocular lens (IOL) by evaluating postoperative changes.
    Setting: Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    Methods: Forty eyes of 20 patients with IOL implantation were randomized into 2 groups according to IOL type: 3-piece silicone multifocal IOL or 3-piece acrylic IOL. All lenses were implanted in the capsular bag through a clear corneal incision after continuous curvilinear capsulorhexis and phacoemulsification. The amount of the decentration and the degree of the tilt of each IOL were measured using the EAS-1000 anterior eye segment analysis system 1 day and 1 and 2 months after surgery.
    Results: No significant difference in decentration and tilt was found among the 3 follow-ups or between lens types.
    Conclusion: Neither IOL decentration nor tilt showed significant progression up to 2 months in eyes with a silicone multifocal or acrylic IOL when the IOLs were placed properly in the capsular bag. The amount of decentration and tilt was similar between lens types.
    MeSH term(s) Acrylic Resins ; Aged ; Biocompatible Materials ; Capsulorhexis ; Female ; Foreign-Body Migration/etiology ; Humans ; Lens Implantation, Intraocular ; Lenses, Intraocular ; Male ; Middle Aged ; Phacoemulsification ; Prospective Studies ; Prosthesis Design ; Prosthesis Failure ; Refraction, Ocular ; Silicone Elastomers ; Visual Acuity
    Chemical Substances Acrylic Resins ; Biocompatible Materials ; Silicone Elastomers
    Language English
    Publishing date 2000-04
    Publishing country United States
    Document type Clinical Trial ; Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1016/s0886-3350(99)00401-0
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  8. Article ; Online: Impact of tumor infiltration pattern into the surrounding tissue on prognosis of the subserosal gastric cancer (pT2b).

    Song, K Y / Hur, H / Jung, C K / Jung, E S / Kim, S N / Jeon, H M / Park, C H

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2010  Volume 36, Issue 6, Page(s) 563–567

    Abstract: Background: The aim of this study was to clarify the impact of infiltration pattern on prognosis in patients with gastric carcinoma invading subserosa.: Methods: Clinicopathologic findings in patients with ssgamma pattern (n = 144) were compared with ...

    Abstract Background: The aim of this study was to clarify the impact of infiltration pattern on prognosis in patients with gastric carcinoma invading subserosa.
    Methods: Clinicopathologic findings in patients with ssgamma pattern (n = 144) were compared with those in patients with ssalpha/ssbeta cancers (n = 222). Prognostic factors of pT2b patients were analyzed by univariate and multivariate analysis.
    Results: Compared with the ssalpha/beta group, ssgamma gastric cancer exhibited more frequent undifferentiated histology, disseminated lymph node metastasis and perineural invasion. Frequency of postoperative peritoneal recurrence was significantly higher in ssgamma gastric cancer (P < 0.05). The 5-year survival rate for patients with ssgamma gastric cancer was significantly lower compared with ssalpha/beta group (63.2% vs. 74.8%, respectively; P < 0.05). Lymph node metastasis, vein invasion and infiltrative pattern (ssgamma) were significant independent prognostic factors affecting survival in pT2b patients.
    Conclusion: In patients with gastric cancer invading the subserosa, infiltrative type growth pattern is closely related to carcinomatosis and poorer prognosis.
    MeSH term(s) Female ; Gastric Mucosa/pathology ; Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Invasiveness ; Neoplasm Staging ; Peritoneal Neoplasms/pathology ; Predictive Value of Tests ; Prognosis ; Stomach Neoplasms/pathology ; Survival Rate
    Language English
    Publishing date 2010-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2010.04.006
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  9. Article ; Online: Case report. Lipomatous haemangiopericytoma (fat-forming solitary fibrous tumour) involving the perineum: CT and MRI findings and pathological correlation.

    Kim, M Y / Rha, S E / Oh, S N / Lee, Y J / Byun, J Y / Jung, C K / Kang, W K

    The British journal of radiology

    2009  Volume 82, Issue 974, Page(s) e23–6

    Abstract: Lipomatous haemangiopericytoma (a fat-forming solitary fibrous tumour) is a rare soft-tissue tumour histologically characterized by haemangiopericytomatous vasculature and the presence of mature adipocytes. We report the CT and MRI findings of a case of ... ...

    Abstract Lipomatous haemangiopericytoma (a fat-forming solitary fibrous tumour) is a rare soft-tissue tumour histologically characterized by haemangiopericytomatous vasculature and the presence of mature adipocytes. We report the CT and MRI findings of a case of lipomatous haemangiopericytoma involving the perineum. CT showed a well-circumscribed soft-tissue density mass containing a small area of fat density and a punctuate calcification. On MR images, the mass was mostly isointense to the muscle on T(1) weighted images, with heterogeneous signal intensity on T(2) weighted images, and showed strong contrast enhancement except for the fatty and dense collagenous components. This is the first case report of imaging findings of a lipomatous haemangiopericytoma in the radiological literature. Although rare, lipomatous haemangiopericytoma should be considered as a differential diagnosis of fat-containing, hypervascular soft-tissue tumours with variable signal intensity on T(2) weighted images.
    MeSH term(s) Adult ; Hemangiopericytoma/diagnosis ; Hemangiopericytoma/diagnostic imaging ; Hemangiopericytoma/pathology ; Humans ; Lipoma/diagnosis ; Lipoma/diagnostic imaging ; Lipoma/pathology ; Magnetic Resonance Imaging ; Male ; Perineum ; Solitary Fibrous Tumors/diagnosis ; Solitary Fibrous Tumors/diagnostic imaging ; Solitary Fibrous Tumors/pathology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2009-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr/26727658
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  10. Article ; Online: Pathological validation of supracricoid partial laryngectomy in laryngeal cancer.

    Sun, D-I / Cho, K-J / Cho, J-H / Joo, Y-H / Jung, C-K / Kim, M-S

    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

    2009  Volume 34, Issue 2, Page(s) 132–139

    Abstract: Objectives: To validate pathologically whether supracricoid partial laryngectomy is an oncologically sound procedure in cases with invasion of the thyroid cartilage, paraglottic space, pre-epiglottic space, anterior commissure, or subglottis.: Design!# ...

    Abstract Objectives: To validate pathologically whether supracricoid partial laryngectomy is an oncologically sound procedure in cases with invasion of the thyroid cartilage, paraglottic space, pre-epiglottic space, anterior commissure, or subglottis.
    Design: A retrospective review of case notes was performed.
    Setting: Patients treated at a single institute in the Republic of Korea.
    Participants: Sixty-three patients who underwent supracricoid partial laryngectomy for laryngeal squamous cell carcinoma between June 1994 and May 2005 who were followed for at least 2 years.
    Main outcome measures: Local control and overall survival rates. Pathological invasion of the thyroid cartilage, anterior commissure, pre-epiglottic space, paraglottic space, or subglottis was also investigated as a cause of recurrence. Prognostic factors for local control and survival were evaluated with univariate and multivariate models.
    Results: Invasion of the anterior commissure, paraglottic space, thyroid cartilage, pre-epiglottic space, or subglottis had no significant impact on the recurrence or overall survival rates. The presence of a positive resection margin was significantly associated with recurrence in the univariate and multivariate analyses (P = 0.026, 0.028, respectively). When considering the prognostic factors influencing survival, the univariate analysis showed that N stage, a positive resection margin and recurrence had significant influences on the overall survival rate (P = 0.010, 0.0004 and 0.000 respectively). In the multivariate analysis, only recurrence affected the survival rate (P = 0.002).
    Conclusion: Supracricoid partial laryngectomy can be used with oncological safety in selected cases of laryngeal cancer with invasion of the anterior commissure, thyroid cartilage, pre-epiglottic space, paraglottic space, or subglottis.
    MeSH term(s) Aged ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/radiotherapy ; Carcinoma, Squamous Cell/surgery ; Combined Modality Therapy ; Cricoid Cartilage/pathology ; Cricoid Cartilage/surgery ; Epiglottis/pathology ; Female ; Follow-Up Studies ; Glottis/pathology ; Humans ; Laryngeal Neoplasms/mortality ; Laryngeal Neoplasms/pathology ; Laryngeal Neoplasms/radiotherapy ; Laryngeal Neoplasms/surgery ; Laryngectomy/methods ; Larynx/pathology ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local/mortality ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Prognosis ; Radiotherapy, Adjuvant ; Survival Analysis ; Thyroid Cartilage/pathology
    Language English
    Publishing date 2009-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2205891-6
    ISSN 1749-4486 ; 1749-4478 ; 0307-7772 ; 1365-2273
    ISSN (online) 1749-4486
    ISSN 1749-4478 ; 0307-7772 ; 1365-2273
    DOI 10.1111/j.1749-4486.2008.01854.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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