Article: Clinical and Swallowing Characteristics Related With Respiratory Infection in Parkinsonism Patients.
Annals of rehabilitation medicine
2023 Volume 47, Issue 2, Page(s) 138–146
Abstract: Objective: To investigate the clinical and swallowing characteristics related to respiratory infection in patients with parkinsonism.: Methods: One hundred and forty-two patients with parkinsonism who underwent videofluoroscopic swallowing studies ( ... ...
| Abstract | Objective: To investigate the clinical and swallowing characteristics related to respiratory infection in patients with parkinsonism. Methods: One hundred and forty-two patients with parkinsonism who underwent videofluoroscopic swallowing studies (VFSS) were enrolled in this study. The initial clinical and VFSS characteristics were compared between patients with and without a history of respiratory infection in the past year. A multivariate logistic regression model was applied to identify clinical and swallowing characteristics related to respiratory infections. Results: Patients with respiratory infections were older (74.75±10.20 years vs. 70.70±8.83 years, p=0.037), had a higher Hoehn and Yahr (H&Y) stage (stage IV-V, 67.9% vs. 49.1%; p=0.047), and were more likely to have a diagnosis of idiopathic Parkinson's disease (IPD) (67.9% vs. 41.2%, p=0.011) than those without respiratory infections. Among VFSS findings, bolus formation, premature bolus loss, oral transit time, pyriform sinus residues, pharyngeal wall coatings, and penetration/aspiration were significantly worse in patients with respiratory infections (p<0.05). Regarding clinical characteristics, higher H&Y stage (odds ratio [OR], 3.174; 95% confidence interval [CI], 1.226-8.216; p=0.017) and diagnosis of IPD (OR, 0.280, 95% CI, 0.111-0.706; p=0.007) were significantly related to respiratory infections in the multivariate analysis. Among VFSS findings, pyriform sinus residue (OR, 14.615; 95% CI, 2.257-94.623; p=0.005) and premature bolus loss (OR, 5.151; 95% CI, 1.047-25.338; p=0.044) were also significantly associated with respiratory infection. Conclusion: This study suggests that disease severity, diagnosis, pyriform sinus residue, and premature bolus loss observed in VFSS are associated with respiratory infection in patients with parkinsonism. |
|---|---|
| Language | English |
| Publishing date | 2023-04-30 |
| Publishing country | Korea (South) |
| Document type | Journal Article |
| ZDB-ID | 2659431-6 |
| ISSN | 2234-0653 ; 2234-0645 |
| ISSN (online) | 2234-0653 |
| ISSN | 2234-0645 |
| DOI | 10.5535/arm.22152 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.