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  1. Article ; Conference proceedings: Akzeptanz von Keuchhustenimpfungen während der Schwangerschaft in Deutschland

    Jung, L

    Das Gesundheitswesen

    2019  Volume 81, Issue 08/09

    Event/congress „Neue Ideen für mehr Gesundheit“, Düsseldorf, 2019-09-16
    Language German
    Publishing date 2019-08-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/s-0039-1694342
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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Conference proceedings: TBC unter Asylbewerbern und Geflüchteten aus der Ukraine – Daten und Fallbeispiele aus 10929 Erstaufnahmeuntersuchungen.

    Tegtmeyer, B. / Alabadla, M. / Jung, L. / Haag-Milz, S.

    Das Gesundheitswesen

    2024  Volume 86, Issue S 02

    Event/congress Der Öffentliche Gesundheitsdienst - Rückenwind für Gesundheit! 73. Wissenschaftlicher Kongress | BVÖGD e.V., BZÖG e.V., DGÖG e.V., Hamburg, 2024-04-24
    Language German
    Publishing date 2024-04-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/s-0044-1781850
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  3. Article ; Conference proceedings: Influence of different ventilation modes of non-invasive ventilation in patients with hypercapnic-hypoxic ventilation failure – iVAPS vs. ST

    Jagomast, T / Jung, L / Lüthgen, M / Drömann, D / Franzen, K

    Pneumologie

    2024  Volume 78, Issue S 01

    Event/congress 64. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V., Mannheim, 2024-03-20
    Language German
    Publishing date 2024-03-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 607630-0
    ISSN 1438-8790 ; 0934-8387
    ISSN (online) 1438-8790
    ISSN 0934-8387
    DOI 10.1055/s-0044-1778837
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    Zs.MO 54: Show issues

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  4. Article ; Online: 19 Effects of recombinant equine intra-articular IL-1 on synovial fluid PGE2 and movement asymmetry: A pilot study

    Jung, L. / St. George, L. / McCrae, P. / Korac, L. / Fraser, A. / Pearson, W.

    Journal of Equine Veterinary Science. 2023 May, v. 124 p.104321-

    2023  

    Abstract: Synovitis is a common feature of osteoarthritis (OA). Exogeneous intra-articular inflammatory compounds such as lipopolysaccharide or interleukin 1β (human or equine) produce a convenient, self-limiting, and reversible synovitis in horses, which can be ... ...

    Abstract Synovitis is a common feature of osteoarthritis (OA). Exogeneous intra-articular inflammatory compounds such as lipopolysaccharide or interleukin 1β (human or equine) produce a convenient, self-limiting, and reversible synovitis in horses, which can be useful to evaluate putative OA interventions. Although biochemical responses to this minimally invasive synovitis model have been described, its effects on functional adaptations in movement remains unclear. The aim of this pilot study was to correlate synovial fluid biochemical responses to intra-articular injection of recombinant equine IL-1b (IL-1) with objective measures of movement asymmetry. Horses (n = 3) randomly received 0, 50 or 75ng reIL-1 in 500μL of sterile saline into the left or right intercarpal joint in a 3-way crossover design, with 50 and 75ng treatments applied to the contralateral carpus and 24 h between treatments. Synovial fluid was collected by aseptic arthrocentesis at 0 (before IL-1 injection), 6, 12 and 24 h after IL-1 injection and analyzed for prostaglandin E₂ (PGE₂) by ELISA. To quantify movement asymmetry, MinDiff was calculated using withersvertical displacement data (2000 Hz) acquired from an inertial measurement unit (IMU) (Delsys Trigno) during in-hand trot trials at each time point/condition. PGE₂ and MinDiff data were analyzed using 2-way repeated measures ANOVA with respect to IL-1 challenge dose and time. Correlations between variables were determined using the Spearman correlation. PGE₂ significantly increased at 6 h (314.4 ± 136.4 pg/mL) compared with 0 h (128.0 ± 43.2 pg/mL) following challenge with 75ng IL-1 (P = 0.04). An increase in MinDiff 6 h following 75ng challenge was not significant (P = 0.13). MinDiff and PGE₂ peaked simultaneously at 6 h after injection of 75ng IL-1, but the correlation was not significant (P = 0.27). Data from this small pilot study indicate that low intra-articular dose of reIL-1b induces measurable increase in local synovial fluid PGE₂, which is a key pro-inflammatory biomarker. Effects on adaptations in gait asymmetry warrant further investigation.
    Keywords asymmetry ; biomarkers ; carpus ; cross-over studies ; gait ; horses ; humans ; interleukin-1 ; lipopolysaccharides ; models ; osteoarthritis ; prostaglandins ; synovial fluid ; synovitis ; veterinary medicine
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier Inc.
    Document type Article ; Online
    ZDB-ID 2102631-2
    ISSN 1542-7412 ; 0737-0806
    ISSN (online) 1542-7412
    ISSN 0737-0806
    DOI 10.1016/j.jevs.2023.104321
    Database NAL-Catalogue (AGRICOLA)

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  5. Book ; Thesis: Zur Ätiologie keilförmiger Defekte der Zahnhartsubstanz

    Jung, Lix

    ein In-vitro-Versuch

    2000  

    Author's details vorgelegt von: Lix Jung
    Language German
    Size 151 S. : Ill.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Bonn, Univ., Diss., 2000
    HBZ-ID HT012755019
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 D 347 order for loan Magazin

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  6. Article: An insight into the runs of homozygosity distribution and breed differentiation in Mangalitsa pigs.

    Addo, Sowah / Jung, Lisa

    Frontiers in genetics

    2022  Volume 13, Page(s) 909986

    Abstract: Mangalitsa pigs exhibit three distinct coat color patterns based on which they are described as Red, Blond, and Swallow-bellied. The current study investigated genome-wide diversity and selection signatures in the three breeds using fixation index, runs ... ...

    Abstract Mangalitsa pigs exhibit three distinct coat color patterns based on which they are described as Red, Blond, and Swallow-bellied. The current study investigated genome-wide diversity and selection signatures in the three breeds using fixation index, runs of homozygosity and population structure analyses. The analyses were originally based on quality-controlled data on 77 Mangalitsa animals from Germany, including 23 Blond, 30 Swallow-bellied and 24 Red Mangalitsa genotyped with a customized version of the ProcineSNP60 v2 Genotyping Bead Chip. Also, 20 Hungarian Mangalitsa genotypes were included as outgroup data for comparison. Estimates of observed heterozygosity were 0.27, 0.28, and 0.29, and inbreeding coefficients estimated based on runs of homozygosity were 24.11%, 20.82%, and 16.34% for Blond, Swallow-bellied and Red Mangalitsa, respectively. ROH islands were detected in all breeds, however, none of these were shared amongst them. The KIF16B gene previously reported to play a role in synaptic signaling was found in a ROH island (SSC17: 16-26) in Swallow-bellied Mangalitsa. The same gene was found to harbor a significantly differentiated SNP (MARC0032380) while contrasting either Blond or Red to Swallow-belied Mangalitsa. In the Red Mangalitsa, some ROH islands were associated with genes that play a role in meat quality traits, i.e., ABCA12, VIL1, PLSCR5, and USP37. Our population structure analysis highlighted a separation of the three breeds, but also showed the closest relatedness between Red and Blond Mangalitsa pigs. Findings of this study improve our understanding of the diversity in the three breeds of Mangalitsa pigs.
    Language English
    Publishing date 2022-10-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.909986
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  7. Article ; Online: Presence of keel bone damage in laying hens, pullets and roosters of local chicken breeds.

    Jung, Lisa / Hillemacher, Sonja / Tiemann, Inga / Lepke, Mascha / Hinrichs, Dirk

    PloS one

    2024  Volume 19, Issue 1, Page(s) e0297586

    Abstract: In commercial laying hens, keel bone damage (KBD) is a severe health and welfare problem leading to pain, reduced mobility and decreased laying performance. Flocks of all production systems and hybrid lines can be affected. KBD is a multifactorial ... ...

    Abstract In commercial laying hens, keel bone damage (KBD) is a severe health and welfare problem leading to pain, reduced mobility and decreased laying performance. Flocks of all production systems and hybrid lines can be affected. KBD is a multifactorial welfare issue and, among other factors, associated with a high laying performance which negatively affects the calcium deposit in the medullary bones. Therefore, mature hens of local breeds with much lower egg production than commercial hybrids may be expected to show less or even no keel bone damage. This study evaluates (i) the prevalence of KBD in local breeds, (ii) the difference in type and level of damages, and (iii) if roosters and pullets are also affected. In total, we palpated 343 mature hens, 40 pullets, and 18 roosters of 13 different local breeds and one commercial hybrid. The animals were kept on eight different farms in free-range or floor-housing systems. Our results showed that on average 44.2% of mature hens per local breed were affected by KBD (range: 11.1%-84.7%). We found deviation of less than 1 cm in 26.9%, deviations of more than 1 cm in 6.4% and palpable fractures in 23.8% of the mature hens of local breeds. The tip was damaged in 23.6% of the mature hens. Also, pullets and roosters were affected by KBD. Finally, we found that KBD also occurs in local breeds. Therefore, we conclude that even the low laying performance of local breeds does not prevent them from the occurrence of KBD.KBD in local breeds may rather be associated with genetics (breed) as well as management and housing. Thus, breeders of local breeds should include bone health as a selection trait. Owners of local breeds should also pay attention to the condition of the keel and ought to be trained about preventive measures.
    MeSH term(s) Animals ; Female ; Male ; Chickens/genetics ; Housing, Animal ; Poultry Diseases/genetics ; Poultry Diseases/epidemiology ; Bone and Bones ; Fractures, Bone/epidemiology ; Animal Welfare
    Language English
    Publishing date 2024-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0297586
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  8. Article: From Satirical Poems and Invisible Poisons to Radical Surgery and Organized Cervical Cancer Screening-A Historical Outline of Cervical Carcinoma and Its Relation to HPV Infection.

    Jung, Leonard / Klamminger, Gilbert Georg / Bier, Bert / Eltze, Elke

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 3

    Abstract: Over the last century, the narrative of cervical cancer history has become intricately tied to virus research, particularly the human papillomavirus (HPV) since the 1970s. The unequivocal proof of HPV's causal role in cervical cancer has placed its ... ...

    Abstract Over the last century, the narrative of cervical cancer history has become intricately tied to virus research, particularly the human papillomavirus (HPV) since the 1970s. The unequivocal proof of HPV's causal role in cervical cancer has placed its detection at the heart of early screening programs across numerous countries. From a historical perspective, sexually transmitted genital warts have been already documented in ancient Latin literature; the remarkable symptoms and clinical descriptions of progressed cervical cancer can be traced back to Hippocrates and classical Greece. However, in the new era of medicine, it was not until the diagnostic-pathological accomplishments of Aurel Babeş and George Nicolas Papanicolaou, as well as the surgical accomplishments of Ernst Wertheim and Joe Vincent Meigs, that the prognosis and prevention of cervical carcinoma were significantly improved. Future developments will likely include extended primary prevention efforts consisting of better global access to vaccination programs as well as adapted methods for screening for precursor lesions, like the use of self-sampling HPV-tests. Furthermore, they may also advantageously involve additional novel diagnostic methods that could allow for both an unbiased approach to tissue diagnostics and the use of artificial-intelligence-based tools to support decision making.
    Language English
    Publishing date 2024-02-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14030307
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  9. Article ; Conference proceedings: Impact of disopables head-to-head to e-cigarettes, and combustible cigarettes on arterial stiffness

    Rabenstein, A / Falarowski, C / Lüthgen, M / Jung, L / Drömann, D / Franzen, K

    Pneumologie

    2024  Volume 78, Issue S 01

    Event/congress 64. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V., Mannheim, 2024-03-20
    Language German
    Publishing date 2024-03-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 607630-0
    ISSN 1438-8790 ; 0934-8387
    ISSN (online) 1438-8790
    ISSN 0934-8387
    DOI 10.1055/s-0044-1778863
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    Zs.MO 54: Show issues

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  10. Article: Urban Traumatic Moving Injuries Before and During SARS-CoV-2: A Multilinear Regression Analysis.

    Jung, Geena / Giordano, Vincent / Harrington, Tara / Jung, Lance

    Cureus

    2023  Volume 15, Issue 3, Page(s) e36905

    Abstract: Background The onset of the coronavirus pandemic (COVID-19/SARS-CoV-2) saw an overall decline in traffic. Fundamental shifts in the pattern of traffic-related traumas were observed across the United States and beyond.  Objectives This study aims to ... ...

    Abstract Background The onset of the coronavirus pandemic (COVID-19/SARS-CoV-2) saw an overall decline in traffic. Fundamental shifts in the pattern of traffic-related traumas were observed across the United States and beyond.  Objectives This study aims to predict changes in the length of stay (LOS) for patients sustaining traumatic moving injuries before and during the coronavirus pandemic.  Methods All moving injuries (bicycle accidents, pedestrians struck, motor vehicle/motorcycle accidents) before and during the first SARS-CoV-2 wave in the US were extracted from our hospital's trauma registry. The study period was from March 1st to October 31st of 2019 and 2020, respectively. Ordinary least squares (OLS) multilinear regression models were estimated with a significance level of 0.05.
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.36905
    Database MEDical Literature Analysis and Retrieval System OnLINE

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