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  1. Article ; Online: Effects of Replacing Fish Meal with Stickwater Hydrolysate and Meal on the Growth, Serum Biochemical Indexes, and Muscle Quality of Yellow Catfish ( Tachysurus fulvidraco )

    Shuang Zheng / Yong Shi / Junzhi Zhang / Jihong Dai / Yi Hu / Lei Zhong

    Fishes, Vol 8, Iss 12, p

    2023  Volume 566

    Abstract: An eight-week feeding experiment was conducted to evaluate the effects of replacing fish meal with stickwater hydrolysate (SWH) or stickwater hydrolysate meal (SWM) on the growth, serum biochemical parameters, intestinal digestive enzyme activity, and ... ...

    Abstract An eight-week feeding experiment was conducted to evaluate the effects of replacing fish meal with stickwater hydrolysate (SWH) or stickwater hydrolysate meal (SWM) on the growth, serum biochemical parameters, intestinal digestive enzyme activity, and muscle quality of yellow catfish ( Tachysurus fulvidraco ). The control diet (CON) contained 30% fish meal and the remaining five diets were substituted for fish meal with 2.5% (SWM2.5), 5% (SWM5) SWM, and 5% (SWH5), 10% (SWH10), and 15% (SWH15) SWH, respectively. The results showed that there were no significant differences in weight gain rate, feed conversion rate, survival rate, hepatosomatic index, and viscerosomatic index among the groups. The substitution of fish meal with SWH significantly augmented the serum triglyceride and total cholesterol levels, whereas urea nitrogen content exhibited a reduction proportional to the replacement ratio. The incorporation of SWH led to a notable rise in glutamate-pyruvate transaminase activity, albeit with a gradual decline as the substitution ratio escalated. Relative to the CON group, the SWH5 group displayed a significant reduction in serum superoxide dismutase activity and a significant elevation in serum catalase activity. The substitution of fish meal with SWM yielded noticeable increments in the activities of complement 3, immunoglobulin M, and alkaline phosphatase. Neither SWH nor SWM exerted a substantial influence on intestinal amylase activity. Regarding muscle characteristics, neither SWH nor SWM showed a marked effect on hardness and springiness; however, adhesiveness, cohesiveness, gumminess, and chewiness properties exhibited enhancement as the proportion of fish meal replacement increased. In conclusion, within this experimental context, substituting fish meal with SWH and SWM did not adversely impact the growth and meat quality of yellow catfish. Specifically, replacing 15% fish meal with stickwater hydrolysate and 5% fish meal with stickwater hydrolysate meal contributed to an enhanced immune capacity in ...
    Keywords Tachysurus fulvidraco ; fish meal substitution ; stickwater hydrolysate (meal) ; growth ; serum biochemistry ; serum immunity ; Biology (General) ; QH301-705.5 ; Genetics ; QH426-470
    Subject code 590
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Factors Driving Microbial Community Dynamics and Potential Health Effects of Bacterial Pathogen on Landscape Lakes with Reclaimed Water Replenishment in Beijing, PR China

    Junzhi Zhang / Xiao He / Huixin Zhang / Yu Liao / Qi Wang / Luwei Li / Jianwei Yu

    International Journal of Environmental Research and Public Health, Vol 19, Iss 5127, p

    2022  Volume 5127

    Abstract: Assessing the bacteria pathogens in the lakes with reclaimed water as major influents are important for public health. This study investigated microbial communities of five landscape lakes replenished by reclaimed water, then analyzed driven factors and ... ...

    Abstract Assessing the bacteria pathogens in the lakes with reclaimed water as major influents are important for public health. This study investigated microbial communities of five landscape lakes replenished by reclaimed water, then analyzed driven factors and identified health effects of bacterial pathogens. 16S rRNA gene sequence analysis demonstrated that Proteobacteria , Actinobacteria , Cyanobacteria , Firmicutes, and Verrucomicrobia were the most dominant phyla in five landscape lakes. The microbial community diversities were higher in June and July than that in other months. Temperature, total nitrogen and phosphorus were the main drivers of the dominant microbial from the Redundancy analysis (RDA) results. Various potential bacterial pathogens were identified, including Pseudomonas , GKS98_freshwater_group , Sporosarcina , Pseudochrobactrum , Streptomyces and Bacillus , etc, some of which are easily infectious to human. The microbial network analysis showed that some potential pathogens were nodes that had significant health effects. The work provides a basis for understanding the microbial community dynamics and safety issues for health effects in landscape lakes replenished by reclaimed water.
    Keywords reclaimed water ; health effects ; microbial community dynamics ; diversity and richness ; driven factors ; pathogens ; Medicine ; R
    Subject code 550
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Sustainability of Reinforced Concrete Beams with/without BF Influenced by Cracking Capacity and Chloride Diffusion

    Yurong Zhang / Chaojun Mao / Jiandong Wang / Yanhong Gao / Junzhi Zhang

    Sustainability, Vol 12, Iss 3, p

    2020  Volume 1054

    Abstract: Concrete’s production causes pronounced environmental impacts. It is confirmed that adding basalt fiber (BF) into concrete can improve the mechanical properties and reduce the chloride diffusion coefficient of concrete. Moreover, research on the ... ...

    Abstract Concrete’s production causes pronounced environmental impacts. It is confirmed that adding basalt fiber (BF) into concrete can improve the mechanical properties and reduce the chloride diffusion coefficient of concrete. Moreover, research on the environmental impact of BF and its application in concrete has gradually emerged in recent years. However, there is little research on the chloride diffusivity of concrete structures with BF under the coupling interaction of external loads and chloride action. Therefore, at first, six beams were cast to obtain the depth-dependent chloride diffusivity of concrete under the coupling interaction of chloride penetration and 50% and 80% of the cracking capacity. Then, a functional unit ( FU ) combining durability, cracking capacity and volume was proposed to evaluate the sustainability of the concrete structure. In addition, three extra FU s (volume, considering volume and cracking capacity simultaneously and considering volume, cracking capacity and durability simultaneously) were also proposed and compared with the first FU . Results indicate that, regardless of the applied load level, the average chloride diffusion coefficient of a reinforced concrete (RC) beam with BF is larger than that of an ordinary RC beam. Moreover, the sorting of life cycle assessment (LCA) results will vary significantly with the different preset functional units. When taking the cracking capacity into consideration, adding BF into concrete is a suitable solution to improve the sustainability of RC beams.
    Keywords environmental aspects ; fiber-reinforced concrete ; permeability and pore-related properties ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Adaptive distributed finite‐time fault‐tolerant controller for cooperative braking of the vehicle platoon

    Jinheng Han / Junzhi Zhang / Chengkun He / Chen Lv / Chao Li / Xiaohui Hou / Yuan Ji

    IET Intelligent Transport Systems, Vol 15, Iss 12, Pp 1562-

    2021  Volume 1581

    Abstract: Abstract Vehicle platooning can significantly reduce traffic accidents and enhance transportation safety. Among many subsystems and functionalities equipped in a vehicle platoon, cooperative braking is a safety‐critical one. Besides, as actuator faults ... ...

    Abstract Abstract Vehicle platooning can significantly reduce traffic accidents and enhance transportation safety. Among many subsystems and functionalities equipped in a vehicle platoon, cooperative braking is a safety‐critical one. Besides, as actuator faults would deteriorate vehicle safety and stability, they pose a great challenge to the platoon, particularly during cooperative braking. To address the aforementioned problems, this study designed an adaptive distributed finite‐time fault‐tolerant controller for vehicle platoons under cooperative braking condition. First, based on the graph theory and vehicle longitudinal dynamics, the cooperative braking model of a platoon is constructed. Then, the models of hydraulic braking system and regenerative braking system are developed with malfunction analysis. Based on the vehicle's fault model and the representation of the platoon consensus errors, an adaptive finite‐time sliding‐mode fault tolerant controller is proposed to maintain consensus between vehicle's states during fault occurring. Further, a distributed adaptive law is presented considering the parameter estimation error and sliding‐mode surface. The finite‐time convergence property and the stability of the proposed controller are demonstrated. Numerical simulations are conducted under different conditions. The simulation results reflected by the control performance and actuators' responses validate the feasibility and effectiveness of the designed control method.
    Keywords Transportation engineering ; TA1001-1280 ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 629
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Effects of Dietary Andrographolide Levels on Growth Performance, Antioxidant Capacity, Intestinal Immune Function and Microbioma of Rice Field Eel ( Monopterus Albus )

    Yong Shi / Lei Zhong / Yanli Liu / Junzhi Zhang / Zhao Lv / Yao Li / Yi Hu

    Animals, Vol 10, Iss 1744, p

    2020  Volume 1744

    Abstract: An eight-week feeding trial was conducted to investigate the effects of dietary andrographolide on the growth performance, antioxidant capacity in the liver, intestinal inflammatory response and microbiota of Monopterus albus . A total of 900 health fish ...

    Abstract An eight-week feeding trial was conducted to investigate the effects of dietary andrographolide on the growth performance, antioxidant capacity in the liver, intestinal inflammatory response and microbiota of Monopterus albus . A total of 900 health fish (25.00 ± 0.15 g) were randomly divided into five groups: AD1 (the basal diet) as the control, and AD2, AD3, AD4 and AD5 groups, which were fed the basal diet supplemented with 75, 150, 225 and 300 mg/kg andrographolide, respectively. The results showed that compared with the control group, dietary andrographolide supplementation (1) significantly increased trypsin and lipase activities in the intestine, and increased the weight gain rate but not significantly; (2) significantly increased the levels of glutathione reductase (GR), glutathione (GSH) and glutathione peroxidase (GPx) and the content of in the liver; significantly decreased the contents of reactive oxygen species (ROS) and malondialdehyde (MDA); remarkably upregulated the Nrf2, SOD1, GSTK and GSTO mRNA levels in the liver; downregulated the Keap1 mRNA level; (3) significantly increased the villi length and goblet cell numbers in the intestine, remarkably upregulated the Occludin mRNA level in the intestine, downregulated the Claudin-15 mRNA level; (4) remarkably upregulated the IL-10, TGF-β1 and TGF-β3 mRNA levels in the intestine; downregulated the IL-12β and TLR-3 mRNA levels; (5) significantly decreased the richness and diversity of the intestinal microbioma, increased the percentages of Fusobacteria and Firmicutes and significantly decreased the percentages of Cyanobacteria and Proteobacteria. In conclusion, these results showed that dietary low-dose andrographolide (75 and 150 mg/kg) promoted growth and antioxidant capacity, regulated the intestinal microbioma, enhanced intestinal physical and immune barrier function in rice field eel.
    Keywords andrographolide ; Monopterus albus ; growth ; antioxidant capacity ; intestinal immune ; intestinal microbioma ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
    Subject code 610
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: TP 53 polymorphisms and melanoma

    Ting He / Jinhu Wu / Yong Chen / Junzhi Zhang

    Journal of Cancer Research and Therapeutics, Vol 11, Iss 2, Pp 409-

    A meta-analysis

    2015  Volume 414

    Abstract: Background: p53 is a tumor suppressor encoded by the TP53 gene. It is critical in activating deoxyribonucleic acid (DNA) repair upon damage, and thus preserving genomic stability. TP53 is implicated in tumor progression. Melanoma results from transformed ...

    Abstract Background: p53 is a tumor suppressor encoded by the TP53 gene. It is critical in activating deoxyribonucleic acid (DNA) repair upon damage, and thus preserving genomic stability. TP53 is implicated in tumor progression. Melanoma results from transformed melanocytes in the skin. Data gathered on the association between the TP53 Arg72, Pro72 (rs1042522; G>C) polymorphism and melanoma are conflicting. Aims: To assess the relationship between the TP53 genotype and the risk of melanoma, we performed a meta-analysis. Materials and Methods: We searched on PubMed for studies of TP53 polymorphism published in English up to 12 th April 2014. For each study, we calculated odds ratio (OR) and 95% confidence interval (CI), assuming frequency of allele comparison, heterozygote comparison, homozygote comparison, dominant, and recessive genetic models. Seven case-control studies were carried out during the meta-analysis. Results: The TP53 Callele was not associated with the risk of melanoma in the frequency of allele comparison (C vs G: OR = 1.031; 95% CI = 0.824-1.290; P < 0.001 for heterogeneity). The TP53 GC genotype was not associated with the risk of melanoma as compared with the GG genotype (GC vs GG: OR = 0.922; 95% CI = 0.716-1.186; P = 0.010 for heterogeneity). The TP53 CC genotype was not associated with the risk of melanoma as revealed by both the homozygote comparison and the recessive genetic model. Analysis of the dominant model also did not indicate a significant association between the TP53 polymorphism and melanoma. Conclusions: This meta-analysis suggests that genotypes for the TP53 rs1042522 G>C polymorphism might not be associated with the risk of melanoma.
    Keywords Genetic polymorphisms ; melanoma ; meta-analysis ; TP53 ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Effect of compressive strength and chloride diffusion on life cycle CO2 assessment of concrete containing supplementary cementitious materials

    Zhang, Yurong / Junzhi Zhang / Wei Luo / Jiandong Wang / Jiale Shi / Huaxia Zhuang / Yuanfeng Wang

    Journal of cleaner production. 2019 May 01, v. 218

    2019  

    Abstract: Using supplementary cementitious materials (SCMs) in concrete is considered as one of the possible solutions to making green concrete. Previous research often analyzed the environmental impact of concrete without considering the influences of compressive ...

    Abstract Using supplementary cementitious materials (SCMs) in concrete is considered as one of the possible solutions to making green concrete. Previous research often analyzed the environmental impact of concrete without considering the influences of compressive strength and durability simultaneously. Such a practice will lead to less rational life cycle assessment (LCA) results, since the service life of concrete could be shortened when durability is poor, especially if concrete is exposed to marine dry-wet environment where chloride ion is intensive. Moreover, Fick’s second law of diffusion was always used to determine the chloride diffusion coefficient of concrete, without considering the influences of convection zone and peak value of chloride concentration. Therefore, this paper proposed an integrated functional unit combining durability (resistance to chloride ion diffusion), compressive strength and volume to evaluate the environmental impact of concrete containing SCMs. The chloride diffusion coefficient was calculated by re-scaling the ‘‘zero’’ of penetration axis to calibrate Fick’s second law of diffusion. In addition, three other functional units (volume, combining volume and compressive strength, combing volume and durability) were also proposed and compared. Results indicate that the selection of functional unit has a significant influence on the LCA results of the studied concrete. Despite the variation with different functional units, concrete containing silica fume or silica fume as well as fly ash shows a consistently superior environmental performance over the ordinary concrete.
    Keywords carbon dioxide ; compression strength ; concrete ; convection ; diffusivity ; durability ; environmental impact ; environmental performance ; fly ash ; life cycle assessment ; silica
    Language English
    Dates of publication 2019-0501
    Size p. 450-458.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2019.01.335
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Synthesis and Evaluation of a New Type of Small Molecule Epigenetic Modulator Containing Imidazo[1,2-b][1,2,4]triazole Motif

    Fan Wu / Jing Zhang / Erchang Shang / Junzhi Zhang / Xiang Li / Bing Zhu / Xiaoguang Lei

    Frontiers in Chemistry, Vol

    2018  Volume 6

    Abstract: Epigenetic modifications such as DNA methylation is important for many cellular processes, such as cell differentiation and cell death. The disorder of epigenetic state is closely related to human diseases, especially cancers. DNA methylation is a well- ... ...

    Abstract Epigenetic modifications such as DNA methylation is important for many cellular processes, such as cell differentiation and cell death. The disorder of epigenetic state is closely related to human diseases, especially cancers. DNA methylation is a well-characterized epigenetic modification which is related to gene silencing and is considered as a repressive epigenetic mark. DNA methylation caused gene repression can be derepressed by chemical agents. Small molecules targeting DNA methyltransferases, histone deacetylases, and other regulatory factors can activate genes silenced by DNA methylation. However, more and more studies have shown that histone deacetylation is not the only downstream event of DNA methylation. Some additional, unknown mechanisms that promote DNA methylation-mediated gene silencing may exist. Recently, through high-throughput screening using a 308,251-member chemical library to identify potent small molecules that derepress an EGFP reporter gene silenced by DNA methylation, we identified seven hit compounds that did not directly target bulk DNA methylation or histone acetylation. Three of them (LX-3, LX-4, LX-5) were proven to selectively activate the p38 MAPK pathway in multiple cell types. In order to identify the exact cellular targets of these compounds, we turn to work on the SAR study of LX-3 by constructing a structurally diverse chemical library based on the imidazo[1,2-b][1,2,4]triazole core structure via diversity-oriented synthesis. Our work provides a general approach to efficiently access diverse heterocyclic molecules with interesting epigenetic modulation activities.
    Keywords epigenetics ; DNA methylation ; gene silence ; structure activity relationship ; p38 MAPK pathway ; Imidazo[1 ; 2-b][1 ; 2 ; 4]triazole ; Chemistry ; QD1-999
    Subject code 570 ; 612
    Language English
    Publishing date 2018-12-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: The influence of accessory energy consumption on evaluation method of braking energy recovery contribution rate

    Li, Ning / Junzhi Zhang / Siyi Zhang / Xiaohui Hou / Yingshuai Liu

    Energy conversion and management. 2018 June 15, v. 166

    2018  

    Abstract: This article discusses the influence of accessory energy consumption on evaluation method of braking energy recovery contribution rate. The energy flow model of three types of the electrified buses were firstly analyzed. Then, methodologies for the ... ...

    Abstract This article discusses the influence of accessory energy consumption on evaluation method of braking energy recovery contribution rate. The energy flow model of three types of the electrified buses were firstly analyzed. Then, methodologies for the economic contribution rate of the brake energy recovery system including accessories and the system without accessories were proposed. The test method of the braking energy recovery efficiency was analyzed and proposed combining with the practical application. Vehicle tests were carried out under the China city bus typical driving cycle. The tests demonstrated that the effect of vehicle accessory system energy consumption on the braking energy recovery contribution rate is very little.
    Keywords energy flow ; energy recovery ; models ; China
    Language English
    Dates of publication 2018-0615
    Size p. 545-555.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2000891-0
    ISSN 0196-8904
    ISSN 0196-8904
    DOI 10.1016/j.enconman.2018.04.040
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Novel control algorithm of braking energy regeneration system for an electric vehicle during safety–critical driving maneuvers

    Lv, Chen / Junzhi Zhang / Yutong Li / Ye Yuan

    Energy conversion and management. 2015 Dec., v. 106

    2015  

    Abstract: This paper mainly focuses on control algorithm of the braking energy regeneration system of an electric bus under safety–critical driving situations. With the aims of guaranteeing vehicle stability in various types of tyre–road adhesion conditions, ... ...

    Abstract This paper mainly focuses on control algorithm of the braking energy regeneration system of an electric bus under safety–critical driving situations. With the aims of guaranteeing vehicle stability in various types of tyre–road adhesion conditions, based on the characteristics of electrified powertrain, a novel control algorithm of regenerative braking system is proposed for electric vehicles during anti-lock braking procedures. First, the models of vehicle dynamics and main components including braking energy regenerative system of the case-study electric bus are built in MATLAB/Simulink. Then, based on the phase-plane method, the optimal brake torque is calculated for ABS control of vehicle. Next, a novel allocation strategy, wherein the target optimal brake torque is divided into two parts that are handled separately by the regenerative and friction brakes, is developed. Simulations of the proposed control strategy are conducted based on system models built using MATLAB/Simulink. The simulation results demonstrate that the developed strategy enables improved control in terms of vehicle stability and braking performance under different emergency driving conditions. To further verify the synthesized control algorithm, hardware-in-the-loop tests are also performed. The experimental results validate the simulation data and verify the feasibility and effectiveness of the developed control algorithm.
    Keywords adhesion ; algorithms ; energy ; friction ; models ; torque ; vehicles (equipment)
    Language English
    Dates of publication 2015-12
    Size p. 520-529.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2000891-0
    ISSN 0196-8904
    ISSN 0196-8904
    DOI 10.1016/j.enconman.2015.09.062
    Database NAL-Catalogue (AGRICOLA)

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