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Article ; Online: Impact of adenoid hypertrophy on the open bite in children.

Poddębniak, Justyna / Zielnik-Jurkiewicz, Beata

Otolaryngologia polska = The Polish otolaryngology

2019 Volume 73, Issue 4, Page(s) 8–13

Abstract: Nasal obstruction caused by adenoid hypertrophy can lead to malocclusion. The research material consisted of children aged 7-12 years with adenoid hypertrophy qualified for adenoidectomy. On the basis of the conducted tests (laryngological, orthodontic, ... ...

Abstract	Nasal obstruction caused by adenoid hypertrophy can lead to malocclusion. The research material consisted of children aged 7-12 years with adenoid hypertrophy qualified for adenoidectomy. On the basis of the conducted tests (laryngological, orthodontic, pediatric), the occurrence of open frontal bite in children with pharyngeal tonsil hypertrophy, in particular in boys, was confirmed in comparison to children without hypertrophy correctly breathing through the nose.
MeSH term(s)	Adenoidectomy/methods ; Adenoids/pathology ; Adenoids/surgery ; Child ; Female ; Humans ; Hypertrophy/complications ; Hypertrophy/surgery ; Male ; Nasal Obstruction/etiology ; Nasal Obstruction/surgery
Language	English
Publishing date	2019-08-31
Publishing country	Poland
Document type	Journal Article
ZDB-ID	417458-6
ISSN	2300-8423 ; 0030-6657
ISSN (online)	2300-8423
ISSN	0030-6657
DOI	10.5604/01.3001.0013.1536
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Article ; Online: Bacterial lysates in the prevention of respiratory tract infections.

Jurkiewicz, Dariusz / Zielnik-Jurkiewicz, Beata

Otolaryngologia polska = The Polish otolaryngology

2018 Volume 72, Issue 5, Page(s) 1–8

Abstract: Bacterial lysates stimulate the general immunity of the body in a non-specific way. They act on non-specific defense mechanisms, leading to an increase in type A antibody in mucous membranes, phagocytic activity and INF-ƴ production. They can also ... ...

Abstract	Bacterial lysates stimulate the general immunity of the body in a non-specific way. They act on non-specific defense mechanisms, leading to an increase in type A antibody in mucous membranes, phagocytic activity and INF-ƴ production. They can also stimulate the production of specific antibodies against the bacterial antigens that make up the preparation. The oral immunomodulatory preparations with the best documented clinical efficacy available on the Polish market are Ismigen, Broncho-Vaxom, Ribomunyl and Luivac. They are all lysates of bacterial strains that most often cause respiratory tract infections. In many clinical trials, oral bacterial lysates have been shown to minimize the risk of recurrent respiratory infections in children and adults and reduce the need for antibiotics.
MeSH term(s)	Adjuvants, Immunologic/therapeutic use ; Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Antigens, Bacterial/therapeutic use ; Bacterial Infections/drug therapy ; Bacterial Infections/immunology ; Bacterial Vaccines/therapeutic use ; Cell Extracts/therapeutic use ; Child ; Child, Preschool ; Drug Dosage Calculations ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Poland ; Respiratory Tract Infections/drug therapy ; Respiratory Tract Infections/immunology ; Young Adult
Chemical Substances	Adjuvants, Immunologic ; Antigens, Bacterial ; Bacterial Vaccines ; Broncho-Vaxom ; Cell Extracts ; LW 50020 ; Ribomunyl
Language	English
Publishing date	2018-11-20
Publishing country	Poland
Document type	Journal Article ; Review
ZDB-ID	417458-6
ISSN	2300-8423 ; 0030-6657
ISSN (online)	2300-8423
ISSN	0030-6657
DOI	10.5604/01.3001.0012.7216
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Article: Surgical treatment methods of urolithiasis in the pediatric population.

Samotyjek, Joanna / Jurkiewicz, Beata / Krupa, Andrzej

Developmental period medicine

2018 Volume 22, Issue 1, Page(s) 88–93

Abstract: Urolithiasis in the pediatric population represents a major challenge associated with both the diagnosis and therapy of the condition. Over the past 25 years, the incidence has increased. The average age of pediatric patients with stones is about 7-8 ... ...

Abstract	Urolithiasis in the pediatric population represents a major challenge associated with both the diagnosis and therapy of the condition. Over the past 25 years, the incidence has increased. The average age of pediatric patients with stones is about 7-8 years and the recurrence rate is 24%-50%. More than 80% of the stones are eliminated spontaneously. The remaining ones require conservative or surgical treatment. Choosing the most appropriate treatment depends on many factors. Surgical procedures in children are the same as in adults. These include extracorporeal shockwave lithotripsy (ESWL), ureterolithotripsy (URSL), retrograde intrarenal surgery (RIRS), percutaneous nephrolithotomy (PCNL) and laparoscopic or open surgery. ESWL is a method of choice for the treatment of stones with a diameter of ≤20 mm located in the upper urinary tract, while PCNL is used in the treatment of deposits ≥1.5 cm located in the upper pole of the kidney, deposits of ≥1.0 cm located in the lower pole of the kidney, as well as hard stones such as cystic or struvite ones. URSL/RIRS is a method for ureteral and renal stones. Open surgery is indicated in cases when anatomical anomalies coexist with urolithiasis, or when the use of PCNL or ESWL is impossible. The ideal procedure should be effective, safe and allow the complete evacuation of the stones after the 1st procedure.
MeSH term(s)	Child ; Humans ; Lithotripsy ; Practice Guidelines as Topic ; Urolithiasis/surgery ; Urologic Surgical Procedures
Language	English
Publishing date	2018-04-10
Publishing country	Poland
Document type	Journal Article ; Review
ZDB-ID	2576573-5
ISSN	1428-345X
ISSN	1428-345X
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Article ; Online: Antibiotic resistance of Streptococcus pneumoniae in children with acute otitis media treatment failure.

Zielnik-Jurkiewicz, Beata / Bielicka, Anna

International journal of pediatric otorhinolaryngology

2015 Volume 79, Issue 12, Page(s) 2129–2133

Abstract: Objectives: The emergence of antibiotic-resistant bacteria is a major cause of treatment failure in children with acute otitis media (AOM). This study aimed to analyze the types of bacterial strains in fluid isolated from the middle ear of children with ...

Abstract	Objectives: The emergence of antibiotic-resistant bacteria is a major cause of treatment failure in children with acute otitis media (AOM). This study aimed to analyze the types of bacterial strains in fluid isolated from the middle ear of children with AOM who did not respond to oral antibiotic treatment. We also determined the antibiotic resistance of the most frequently isolated bacterial strain (Streptococcus pneumoniae) found in these children. Methods: This was a prospective study of 157 children with AOM aged from 6 months to 7 years admitted due to unsuccessful oral antibiotic treatment. All children underwent a myringotomy, and samples of the middle ear fluid were collected for bacteriological examination. Results: Positive bacterial cultures were obtained in 104 patients (66.2%), with Streptococcus pneumoniae (39.69%), Haemophilus influenzae (16.03%) Staphylococcus aureus (16.03%), Staphylococcus haemolyticus (6.9%) and Streptococcus pyogenes (5.34%) found most frequently. The majority (65.4%) of S. pneumoniae strains were penicillin-intermediate-resistant or penicillin-resistant, and 67.2% strains of S. pneumoniae were multidrug-resistant. Conclusions: We identified S. pneumoniae as the most frequently isolated pathogen from the middle ear in children with AOM treatment failure and determined that the majority of strains were antibiotic-resistant. We propose that the microbiological identification of bacterial strains and their degree of antibiotic resistance should be performed prior to therapy in order to choose the most appropriate antibiotic therapy for children with AOM treatment failure.
MeSH term(s)	Acute Disease ; Anti-Bacterial Agents/therapeutic use ; Child ; Child, Preschool ; Drug Resistance, Multiple, Bacterial ; Female ; Haemophilus Infections/complications ; Haemophilus Infections/drug therapy ; Haemophilus influenzae/isolation & purification ; Humans ; Infant ; Male ; Microbial Sensitivity Tests ; Middle Ear Ventilation ; Otitis Media with Effusion/drug therapy ; Otitis Media with Effusion/microbiology ; Otitis Media with Effusion/surgery ; Penicillin Resistance ; Pneumococcal Infections/complications ; Pneumococcal Infections/drug therapy ; Prospective Studies ; Staphylococcal Infections/complications ; Staphylococcal Infections/drug therapy ; Staphylococcus aureus/isolation & purification ; Staphylococcus haemolyticus/isolation & purification ; Streptococcus pneumoniae/drug effects ; Streptococcus pneumoniae/isolation & purification ; Streptococcus pyogenes/isolation & purification ; Treatment Failure
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2015-12
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	754501-0
ISSN	1872-8464 ; 0165-5876
ISSN (online)	1872-8464
ISSN	0165-5876
DOI	10.1016/j.ijporl.2015.09.030
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Article ; Online: Nonkeratinised squamous metaplasia of the urinary bladder in children: a report of case experiences.

Jurkiewicz, Beata / Ząbkowski, Tomasz

BioMed research international

2014 Volume 2014, Page(s) 936970

Abstract: Background: Squamous metaplasia refers to the pathological transformation of the urothelium leading to nonkeratinised stratified squamous metaplasia (N-KSM).: Objective: To present our experiences in the diagnosis and treatment of N-KSM of the ... ...

Abstract	Background: Squamous metaplasia refers to the pathological transformation of the urothelium leading to nonkeratinised stratified squamous metaplasia (N-KSM). Objective: To present our experiences in the diagnosis and treatment of N-KSM of the urinary bladder in children. Materials and methods: In this study, we present our experiences in the diagnosis and treatment of N-KSM of the urinary bladder in children aged from 5 to 17 years. From 2005 to 2013, metaplasia was diagnosed in 119 patients. The reasons behind visiting the hospital were nonspecific intense pain in the abdomen, recurrent urinary tract infections, and urination disorders. The most common symptoms of urinary bladder dysfunction were pollakiuria and difficulties in initiating micturition and retention of urine (reduced detrusor muscle activity). Results: In 20/119 patients (16.8%), metaplasia was incidentally diagnosed during cystoscopy performed for other causes. The changes characteristic for squamous metaplasia were diagnosed--in all these patients, a biopsy was performed. In all 119 patients, a squamous metaplasia was histopathologically diagnosed. Conclusions: Squamous metaplasia of the urinary bladder mucosa occurs in children and adolescents. Symptomatic treatment is administered mainly to improve the patients' quality of life and disease prognosis.
MeSH term(s)	Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Metaplasia ; Progesterone/blood ; Urinary Bladder/cytology ; Urinary Bladder/pathology ; Urinary Bladder/physiopathology ; Urinary Bladder Diseases ; Urination Disorders
Chemical Substances	Progesterone (4G7DS2Q64Y)
Language	English
Publishing date	2014-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2014/936970
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Article: Pediatric Multisystem Inflammatory Syndrome in Children as a Challenging Problem for Pediatric Surgeons in the COVID 19 Pandemic-A Case Report.

Jurkiewicz, Beata / Szymanek-Szwed, Magdalena / Hartmann, Piotr / Samotyjek, Joanna / Brędowska, Eliza / Kaczorowska, Joanna / Wajszczuk, Ewa / Twardowska-Merecka, Martyna / Cybulska, Joanna

Frontiers in pediatrics

2021 Volume 9, Page(s) 677822

Abstract: The first cases of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection were identified at the end of 2019 and, in the next few months, coronavirus disease (COVID-19) spread throughout the world. Initially, it was believed that this ... ...

Abstract	The first cases of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection were identified at the end of 2019 and, in the next few months, coronavirus disease (COVID-19) spread throughout the world. Initially, it was believed that this disease mainly affected elderly individuals with comorbidities, in whom respiratory failure often occurs. It was believed that children fell ill from the infection more often, although the course of infection in the vast majority of pediatric cases has been asymptomatic or mildly symptomatic. In April and May 2020, the first report of a rapidly progressing disease, similar to Kawasaki syndrome, was found in children who had been infected with SARS-CoV-2. Shortly thereafter, children with symptoms of pediatric inflammatory multisystem syndrome (PIMS-ST [temporally associated with SARS-CoV-2 infection]) began presenting to pediatric hospitals around the world. The syndrome has a mortality rate of up to 2%. Symptoms of PIMS-TS include those that may suggest the need for surgical treatment (severe abdominal pain with the presence of peritoneal symptoms, ascites, high levels of inflammatory markers, intestinal inflammation, and appendages revealed on ultrasound examination). However, there are few reports addressing surgical cases associated with this condition. The authors present a case involving an 11-year-old boy who was admitted to hospital with severe abdominal pain and underwent surgery for symptoms of peritonitis and was diagnosed with PIMS in the post-operative period. Due to the large number of illnesses caused by SARS-CoV-2 infection in recent months, the diagnosis of PIMS-TS/MISC should be considered in the differential diagnosis of acute abdominal symptoms, especially in atypical courses and interviews indicating exposure to SARS-CoV-2.
Language	English
Publishing date	2021-06-11
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2711999-3
ISSN	2296-2360
ISSN	2296-2360
DOI	10.3389/fped.2021.677822
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Article: High-Normal Arterial Blood Pressure in Children With Excess Body Weight.

Kolpa, Malgorzata / Jankowicz-Szymanska, Agnieszka / Jurkiewicz, Beata

Iranian journal of pediatrics

2016 Volume 26, Issue 4, Page(s) e4677

Abstract: Background: Childhood overweight and obesity are common causes of metabolic disorders that persist until adulthood.: Objectives: The purpose of this study was to determine the prevalence of high-normal arterial blood pressure (ABP) in children with ... ...

Abstract	Background: Childhood overweight and obesity are common causes of metabolic disorders that persist until adulthood. Objectives: The purpose of this study was to determine the prevalence of high-normal arterial blood pressure (ABP) in children with excess body weight. Material and methods: A total of 1,093 schoolchildren aged 10 - 12 years (51% girls and 49% boys) participated in the study. The children's weight, height, body fat percentage (BFP), waist and hip circumference, and ABP were measured. The waist-to-height ratio (WHtR) and body mass index (BMI) were calculated and compared to the normative reference values accepted by the International obesity task force (IOTF). Results: Excess weight was identified in 20% of the participants, and obesity in 5%. A total of 35.5% of overweight children had above-normal ABP, which implied hypertension. In obese children, that proportion equaled 59.3%. BFP was 6.5% greater in children with hypertension than in those with normal BP. The children with hypertension also had a 7.6-cm larger waist circumference, a 7.6-cm larger hip circumference, and a greater WHtR (by 0.04). Conclusions: Excess body weight was identified in 25% of children aged 10 - 12 years, significantly increasing their risk of developing hypertension.
Language	English
Publishing date	2016-06-18
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2388780-1
ISSN	2008-2150 ; 2008-2142
ISSN (online)	2008-2150
ISSN	2008-2142
DOI	10.5812/ijp.4677
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Article: Evaluation of the Interleukin-1 Receptor Antagonist and Immunoregulatory Interleukin-10 in the Middle Ear in Chronic Otitis Media With Effusion in Children With and Without Atopy.

Zielnik-Jurkiewicz, Beata / Stankiewicz-Szymczak, Wanda

Clinical and experimental otorhinolaryngology

2016 Volume 9, Issue 2, Page(s) 104–108

Abstract: Objectives: The role of pro-inflammatory cytokines in the course of chronic otitis media with effusion (COME) has been documented. However, there are fewer studies on the action of anti-inflammatory cytokines in the middle ear. We sought determine ... ...

Abstract	Objectives: The role of pro-inflammatory cytokines in the course of chronic otitis media with effusion (COME) has been documented. However, there are fewer studies on the action of anti-inflammatory cytokines in the middle ear. We sought determine whether there is an association between COME and anti-inflammatory cytokines and whether there are any differences in the cytokine profile in COME children with and without atopy. Methods: Eighty-four children were divided into 3 groups: 32 nonatopic children with COME (group NA), 31 atopic children with COME (group A), and 21 children without COME and without atopy (control group C). Specimens from the middle ear were collected and evaluated by enzyme-linked immunosorbent assay for the cytokines interleukin-1 receptor antagonist (IL-1Ra) and immunoregulatory IL-10. Results: Significantly higher IL-10 concentrations were found in both nonatopic and atopic children with COME compared to controls. No significant differences in IL-1Ra levels were found between atopic and nonatopic children with COME and the control group. Conclusion: We found no differences in the levels of IL-1Ra in atopic and nonatopic children with COME compared to controls. However, we found elevated IL-10 levels in the middle ear effusions from children with COME, with or without atopy. These elevated immunoregulatory cytokine levels suggest a role for new immunomodulatory treatments to prevent disease progression in COME, regardless of atopy.
Language	English
Publishing date	2016-04-19
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2491719-9
ISSN	2005-0720 ; 1976-8710
ISSN (online)	2005-0720
ISSN	1976-8710
DOI	10.21053/ceo.2015.00129
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Article ; Online: Pro-inflammatory interleukins in middle ear effusions from atopic and non-atopic children with chronic otitis media with effusion.

Zielnik-Jurkiewicz, Beata / Stankiewicz-Szymczak, Wanda

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

2016 Volume 273, Issue 6, Page(s) 1369–1378

Abstract: Chronic otitis media with effusion (OME) is associated with irreversible changes in the middle ear, sometimes leading to hearing loss and abnormal language development in children. While the pathogenesis of OME is not fully understood, inflammatory and ... ...

Abstract	Chronic otitis media with effusion (OME) is associated with irreversible changes in the middle ear, sometimes leading to hearing loss and abnormal language development in children. While the pathogenesis of OME is not fully understood, inflammatory and allergic factors are thought to be involved. The study aimed to investigate the role of cytokines in the local development of chronic OME, and assess differences in the cytokine profiles between atopic and non-atopic children. 84 atopic and non-atopic children with chronic OME (mean age of 6 years 7 months) were studied. Age-matched children with hypertrophy of the adenoids and Eustachian tube dysfunction served as the control group. The number of past acute otitis media (AOM) episodes, their age, and the type of effusion were recorded for all children. Pro-inflammatory cytokine concentrations (TNF-α, IL-1β, IL-6 and IL-8) were determined and the presence of pathogenic bacteria in the patients' effusions was examined. High concentrations of TNF-α, IL-1β, IL-6 and IL-8 were found in the effusions in all children with chronic OME, with the highest levels observed in the non-atopic group. The atopic group showed persistently high IL-1β levels, while in the non-atopic children, IL-1β and TNF-α levels positively correlated with the patient's age and the number of past AOM episodes. Pathogenic bacteria were more frequently isolated from effusions in non-atopic children. In both atopic and non-atopic children, pro-inflammatory cytokines are found at high concentrations. This argues in favor of instituting anti-inflammatory management for treating OME, regardless of atopy.
MeSH term(s)	Case-Control Studies ; Child ; Child, Preschool ; Chronic Disease ; Ear, Middle ; Female ; Hearing Loss/etiology ; Humans ; Interleukin-1beta/analysis ; Interleukin-1beta/metabolism ; Interleukin-6/analysis ; Interleukin-6/metabolism ; Interleukin-8/analysis ; Interleukin-8/metabolism ; Interleukins/analysis ; Interleukins/metabolism ; Male ; Otitis Media with Effusion/etiology ; Otitis Media with Effusion/metabolism ; Otitis Media with Effusion/microbiology ; Tumor Necrosis Factor-alpha/analysis ; Tumor Necrosis Factor-alpha/metabolism
Chemical Substances	Interleukin-1beta ; Interleukin-6 ; Interleukin-8 ; Interleukins ; Tumor Necrosis Factor-alpha
Language	English
Publishing date	2016-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1017359-6
ISSN	1434-4726 ; 0937-4477
ISSN (online)	1434-4726
ISSN	0937-4477
DOI	10.1007/s00405-015-3683-9
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Article: Zakazenia górnych dróg oddechowych u dzieci wywołane przez bakterie atypowe.

Zielnik-Jurkiewicz, Beata

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego

2008 Volume 25, Issue 149, Page(s) 415–419

Abstract: Unlabelled: It encounters despite solid progress in development of diagnostic methods diagnostics the diseases of upper respiratory tract and ears in children called out by atypical bacteria's on the ground clinical symptoms and their treatment is ... ...

Title translation	Upper respiratory tract infections in children caused by atypical bacteria.
Abstract	Unlabelled: It encounters despite solid progress in development of diagnostic methods diagnostics the diseases of upper respiratory tract and ears in children called out by atypical bacteria's on the ground clinical symptoms and their treatment is difficulty still. Aim: The performance of accessible review of current literature was on the aim of work opinion of the atypical bacteria's part in evocation the infections the upper respiratory tract and ears in children, and performance of characteristic symptoms of clinical diseases these organs the bacteria's also. Conclusions: The quoted in work results of investigations do not it let on the unambiguous opinion the atypical bacteria part in contagions of infections the upper respiratory tract and ears in children. It seems however, that Mycoplasma pneumoniae answers first of all for evocation the acute infections of upper respiratory tract; however Chlamydophila pneumoniae plays the larger part in illnesses chronic as well as co-existent pathogen in illnesses sharp. Atypical bacteria can cause upper respiratory tract infections significantly more often than previously thought. These infections often occur in patients with history of respiratory recurrences.
MeSH term(s)	Atypical Bacterial Forms/classification ; Atypical Bacterial Forms/isolation & purification ; Bacterial Infections/diagnosis ; Bacterial Infections/microbiology ; Child ; Chlamydophila pneumoniae/isolation & purification ; Humans ; Mycoplasma pneumoniae/isolation & purification ; Otitis/microbiology ; Respiratory Tract Infections/microbiology
Language	Polish
Publishing date	2008-11
Publishing country	Poland
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	1388406-2
ISSN	1426-9686
ISSN	1426-9686
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