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  1. Article ; Online: Birth Preparedness and Complication Readiness among Pregnant Women in a Secondary Health Facility in Abakaliki, Ebonyi State, Nigeria

    Chidebe Christian Anikwe / Bartholomew Chukwunonye Okorochukwu / Cyril Chijioke Ikeoha / Obiora G. K. Asiegbu / Ugochukwu Uzodimma Nnadozie / Justus Ndulue Eze / Johnson Akuma Obuna / Francis Chigozie Okoroafor

    BioMed Research International, Vol

    2020  Volume 2020

    Abstract: Background. Birth preparedness and complication readiness (BP/CR) concept is based on the premise that preparing for birth and being ready for complications reduce all three phases of delay to a bad obstetric outcome. Objectives. To determine the ... ...

    Abstract Background. Birth preparedness and complication readiness (BP/CR) concept is based on the premise that preparing for birth and being ready for complications reduce all three phases of delay to a bad obstetric outcome. Objectives. To determine the knowledge of BP/CR with its determinants and BP/CR index among pregnant women in Abakaliki, southeast Nigeria. Methods. A cross-sectional survey was done between 1st March 2019 and 31st July 2019 among 450 randomly selected antenatal attendees at Mile Four Hospital, Abakaliki, Nigeria. The data were obtained using a pretested interviewer-administered structured questionnaire adapted from the maternal and neonatal health program handbook of the Johns Hopkins Program for International Education in Gynaecology and Obstetrics (JHPIEGO). The data obtained were analyzed using percentages, chi-square, and odds ratios. The level of significance is at P value < 0.05. Results. The birth preparedness and complication readiness index was 41.9%. Only 44.9% and 36.9% of the study population had adequate knowledge of birth preparedness (BP) and complication readiness (CR), respectively. Upper social class, lower educational level, urban residence, and less than 30 years of age were associated with increased odds of respondents having adequate knowledge of BP and CR (P>0.05). However, only booking in the 1st or 2nd trimester was a significant determinant of the respondent’s adequate knowledge of BP (AOR=0.63, 95% CI 0.40-0.98) and CR (AOR=0.62, 95% CI 0.39-0.97). Identification of transport and saving of money was the commonest birth plan while the commonest danger sign known to the participants was bleeding. Conclusion. This study revealed that knowledge of BP/CR is suboptimal. The determinant of this knowledge is antenatal booking. It is recommended that women should have adequate antenatal care education to improve their knowledge of BP/CR. This will help to increase the low BP/CR index seen in our study.
    Keywords Medicine ; R
    Subject code 300
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Pregnancy Outcome among Elderly Primigravidae

    Okechukwu Bonaventure Anozie / Johnbosco Emmanuel Mamah / Chidi U Esike / Obiora Godfrey Asiegbu / Lucky Osaheni Lawani / Justus Ndulue Eze / Robinson Chukwudi Onoh

    Journal of Clinical and Diagnostic Research, Vol 13, Iss 1, Pp QC01-QC

    A Five-year Review at Abakaliki, Ebonyi State, Nigeria

    2019  Volume 04

    Abstract: Introduction: Maternal age is an important determinant of pregnancy outcome and women aged 35 years or more at their first pregnancy are considered high risk pregnancy due to increased risk of feto-maternal morbidity and mortality. Aim: To evaluate the ... ...

    Abstract Introduction: Maternal age is an important determinant of pregnancy outcome and women aged 35 years or more at their first pregnancy are considered high risk pregnancy due to increased risk of feto-maternal morbidity and mortality. Aim: To evaluate the outcome of pregnancy in primigravid women who were aged 35 years and above. Materials and Methods: A five-year retrospective study among elderly primigravidae was conducted. The study assessed 78 booked primigravidae aged 35 years or more who delivered at the Federal Teaching Hospital Abakaliki from 1st January 2012 to 31st December 2016. Each elderly primigravida was matched with two primigravid women aged 20-25 years who delivered during the same period. Postnatal visit was also assessed. Results: During the study period, there were 11,329 deliveries and 78 of these were elderly primigravidae giving an incidence of 0.69% or 1:145 deliveries. The mean age of the elderly primigravidae was 36.28±1.20 years. The study group had more antepartum complications with anaemia, antepartum haemorrhage, hypertensive disorders of pregnancies, diabetes mellitus and preterm labour (p<0.05). Intrapartum complications such as poor progress of labour and cephalo-pelvic disproportion were also significantly higher. Almost half of the study group were delivered by caesarean section, the commonest indication being maternal request based on prolonged infertility (16.67%). The study group had higher incidence of preterm delivery and perinatal mortality of significant proportion. However, they were more likely to come for the 6th week postnatal visit 71.2% versus 32.1%. Conclusion: The problems of elderly primigravidae are still germane and relevant in present day obstetrics. Efforts should be intensified towards identifying this high-risk group with a view to take proactive measures aimed at minimising pregnancy related complications so as to achieve the best outcome for them and their babies.
    Keywords advanced maternal age ; maternal morbidity ; parturient ; perinatal complications ; reproductive outcome ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Knowledge, Attitude and Practice of Healthcare Managers to Medical Waste Management and Occupational Safety Practices

    Okechukwu Bonaventure Anozie / Lucky Osaheni Lawani / Justus Ndulue Eze / Emmanuel Johnbosco Mamah / Robinson Chukwudi Onoh / Emeka Onwe Ogah / Daniel Akuma Umezurike / Rita Onyinyechi Anozie

    Journal of Clinical and Diagnostic Research, Vol 11, Iss 3, Pp IC01-IC

    Findings from Southeast Nigeria

    2017  Volume 04

    Abstract: Introduction: Awareness of appropriate waste management procedures and occupational safety measures is fundamental to achieving a safe work environment, and ensuring patient and staff safety. Aim: This study was conducted to assess the attitude of ... ...

    Abstract Introduction: Awareness of appropriate waste management procedures and occupational safety measures is fundamental to achieving a safe work environment, and ensuring patient and staff safety. Aim: This study was conducted to assess the attitude of healthcare managers to medical waste management and occupational safety practices. Materials and Methods: This was a cross-sectional study conducted among 54 hospital administrators in Ebonyi state. Semi-structured questionnaires were used for qualitative data collection and analyzed with SPSS statistics for windows (2011), version 20.0 statistical software (Armonk, NY: IBM Corp). Results: Two-fifth (40%) of healthcare managers had received training on medical waste management and occupational safety. Standard operating procedure of waste disposal was practiced by only one hospital (1.9%), while 98.1% (53/54) practiced indiscriminate waste disposal. Injection safety boxes were widely available in all health facilities, nevertheless, the use of incinerators and waste treatment was practiced by 1.9% (1/54) facility. However, 40.7% (22/54) and 59.3% (32/54) of respondents trained their staff and organize safety orientation courses respectively. Staff insurance cover was offered by just one hospital (1.9%), while none of the hospitals had compensation package for occupational hazard victims. Over half (55.6%; 30/54) of the respondents provided both personal protective equipment and post exposure prophylaxis for HIV. Conclusion: There was high level of non-compliance to standard medical waste management procedures, and lack of training on occupational safety measures. Relevant regulating agencies should step up efforts at monitoring and regulation of healthcare activities and ensure staff training on safe handling and disposal of hospital waste.
    Keywords health hazard ; healthcare workers ; medical waste disposal ; occupational exposure ; Medicine ; R
    Language English
    Publishing date 2017-03-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: A standardised Phase III clinical trial framework to assess therapeutic interventions for Lassa fever.

    Adebola Tolulope Olayinka / Josephine Bourner / George O Akpede / Joseph Okoeguale / Chukwuyem Abejegah / Nnennaya A Ajayi / Christian Akude / Oluwafemi Ayodeji / Daniel G Bausch / Hilde de Clerck / Chioma Dan-Nwafor / Jake Dunning / Cyril Erameh / Justus Ndulue Eze / Pierre Formenty / Annelies Gillesen / Sulaiman Jalloh / Marie Jaspard / Tolulope Jegede /
    Jacob Maikere / Denis Malvy / Ephraim Ogbaini-Emovon / Olalekan Ezekial Ojo / Sylvanus Okogbenin / Kwame O'Neill / Maria-Lauretta Orji / Sampson Omagbemi Owhin / Michael Ramharter / Robert J Samuels / Nathan Shehu / Laura Merson / Alex Paddy Salam / Nzelle Delphine Kayem / Peter Horby / Chikwe Ihekweazu / Piero Olliaro

    PLoS Neglected Tropical Diseases, Vol 16, Iss 1, p e

    2022  Volume 0010089

    Abstract: Background Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. This recommendation is primarily based on evidence generated from a single clinical trial that ...

    Abstract Background Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. This recommendation is primarily based on evidence generated from a single clinical trial that was conducted more than 30 years ago-the methodology and results of which have recently come under scrutiny. The requirement for novel therapeutics and reassessment of ribavirin is therefore urgent. However, a significant amount of work now needs to be undertaken to ensure that future trials for LF can be conducted consistently and reliably to facilitate the efficient generation of evidence. Methodology We convened a consultation group to establish the position of clinicians and researchers on the core components of future trials. A Core Eligibility Criteria (CEC), Core Case Definition (CCD), Core Outcome Set (COS) and Core Data Variables (CDV) were developed through the process of a multi-stakeholder consultation that took place using a modified-Delphi methodology. Results A consensus position was achieved for each aspect of the framework, which accounts for the inclusion of pregnant women and children in future LF clinical trials. The framework consists of 8 core criteria, as well as additional considerations for trial protocols. Conclusions This project represents the first step towards delineating the clinical development pathway for new Lassa fever therapeutics, following a period of 40 years without advancement. Future planned projects will bolster the work initiated here to continue the advancement of LF clinical research through a regionally-centred, collaborative methodology, with the aim of delineating a clear pathway through which LF clinical trials can progress efficiently and ensure sustainable investments are made in research capacity at a regional level.
    Keywords Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
    Subject code 670
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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