LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 4 of total 4

Search options

  1. Article: Borna disease virus: evidence of naturally-occurring infection in cats in Australia

    KAMHIEH, SUNDRELA

    APMIS. 2008 June., v. 116, suppl. 124

    2008  

    Language English
    Dates of publication 2008-06
    Size p. 50-52.
    Publisher Blackwell Publishing Ltd
    Publishing place Oxford, UK
    Document type Article
    ISSN 0108-0172 ; 0903-465X ; 0903-4641
    ISSN 0108-0172 ; 0903-465X ; 0903-4641
    DOI 10.1111/j.1600-0463.2008.000m7.x
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  2. Article: Letter to the Editor refuting "Epidemiological pattern of classical Borna disease and regional genetic clustering of Borna disease viruses point towards the existence of to-date unknown endemic reservoir host populations" by Ralf Dürrwald, Jolanta Kolodziejek, Aemero Muluneh, Sibylle Herzog and Norbert Nowotny, Microbes and Infection 8 (2006) 917-929.

    Flower, Robert / Kamhieh, Sundrela

    Microbes and infection

    2006  Volume 8, Issue 5, Page(s) 1419–20; author reply 1421–2

    MeSH term(s) Animals ; Borna Disease/epidemiology ; Borna Disease/virology ; Borna disease virus/classification ; Borna disease virus/genetics ; Cats ; Disease Reservoirs ; Dogs ; Genetic Variation ; Humans ; Molecular Sequence Data ; Phylogeny
    Language English
    Publishing date 2006-04
    Publishing country France
    Document type Comment ; Letter
    ZDB-ID 1465093-9
    ISSN 1769-714X ; 1286-4579
    ISSN (online) 1769-714X
    ISSN 1286-4579
    DOI 10.1016/j.micinf.2006.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Borna disease virus: evidence of naturally-occurring infection in cats in Australia.

    Kamhieh, Sundrela / Hodgson, Jennifer L / Bode, Liv / Ludwig, Hanns / Flower, Robert L P

    APMIS. Supplementum

    2008  , Issue 124, Page(s) 50–52

    Abstract: In Europe, Borna disease virus (BDV) infection has been linked with staggering disease. The aim of this study was serological investigation for BDV infection in Australian cats. De-identified sera were obtained from domestic cats presented at various ... ...

    Abstract In Europe, Borna disease virus (BDV) infection has been linked with staggering disease. The aim of this study was serological investigation for BDV infection in Australian cats. De-identified sera were obtained from domestic cats presented at various veterinary clinics. BDV antigen levels were measured by a monoclonal antibody-based ELISA. Antibody to BDV measured semiquantitatively by ELISA was detected in 0.8% of cats from South Australia and 3.2% of animals from NSW Confirmatory assays for ELISA positive samples included Western blot and immunofluorescence assay (IFA) with BDV-specific staining. Seven BDV-antigen positive sera (2.4%) were identified in sera from cats from New South Wales (NSW). In blinded testing, amongst a large number of negative results, repeat submissions over a seven-month period from a cat co-infected with Feline Immunodeficiency Virus (FIV) were BDV-antigen positive. Anti-BDV antibody detected in this cat by ELISA was confirmed by Western blot (p24/ p40/p56) and IFA. For 4 other anti-BDV ELISA-positive samples, specific reactions with BDV proteins were observed by Western blot. Ten other anti-BDV ELISA-positive samples were IFA positive. These data provide consistent serological evidence that, while horses in Australia are free of BDV infection, there may be a low rate of BDV infection in cats.
    MeSH term(s) Animals ; Antibodies, Viral/blood ; Antigens, Viral/blood ; Australia/epidemiology ; Blotting, Western ; Borna Disease/blood ; Borna Disease/epidemiology ; Borna disease virus/immunology ; Cat Diseases/blood ; Cat Diseases/epidemiology ; Cats ; Enzyme-Linked Immunosorbent Assay ; Fluorescent Antibody Technique, Indirect ; Seroepidemiologic Studies
    Chemical Substances Antibodies, Viral ; Antigens, Viral
    Language English
    Publishing date 2008-09-03
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 0903-465X
    ISSN 0903-465X
    DOI 10.1111/j.1600-0463.2008.000m7.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Human Borna disease virus infection in Australia: serological markers of infection in multi-transfused patients.

    Flower, Robert L P / Kamhieh, Sundrela / McLean, Loyola / Bode, Liv / Ludwig, Hanns / Ward, Christopher M

    APMIS. Supplementum

    2008  , Issue 124, Page(s) 89–93

    Abstract: Borna disease virus (BDV) causes neurological disease in horses, however, there is no consensus as to the extent or significance of human infection. BDV antigen levels in plasma (BDVpAg) and anti-BDV were measured by ELISAs. Confirmation was by Western ... ...

    Abstract Borna disease virus (BDV) causes neurological disease in horses, however, there is no consensus as to the extent or significance of human infection. BDV antigen levels in plasma (BDVpAg) and anti-BDV were measured by ELISAs. Confirmation was by Western blot (WB), immunofluorescence assay (IFA) or BDV-peptide-epitope ELISA. For 42 volunteers psychiatrically-defined as non-depressed (82 samples) neither BDVpAg nor anti-BDV was detected. For 104 patients with diagnosed depression (290 samples) 1 was BDVpAg positive and 5 anti-BDV positive, one epitope-e8 positive and 4 IFA positive, with 96% concordance for repeat samples. No BDVpAg was detected in 214 pregnant women, 2 were anti-BDV positive, one WB-confirmed (p24/p40). For 219 donors 2 were BDVpAg positive with anti-BDV detected in 5 (2.3%) one IFA 1:10, another IFA 1:40/epitope-e8 positive. In multitransfused patients, 3/168 were BDV pAg positive, with 14/168 anti-BDV positive, 1 epitope-e8 positive, 2 WB positive and 1 IFA 1:10. In BDVpAg positive multi-transfused patients there was an elevated risk of transaminitis. In one case, a patient BDV-negative prior to transfusion was BDVpAg positive for several months posttransfusion (associated with transaminitis). These data provide serological evidence, supported by confirmatory assays and repeat-sample concordance, of BDV infection in Australia, particularly in multi-transfused patients.
    MeSH term(s) Antibodies, Viral/blood ; Antigens, Viral/blood ; Australia/epidemiology ; Blood Transfusion ; Blotting, Western ; Borna Disease/blood ; Borna Disease/epidemiology ; Borna disease virus/immunology ; Depression/blood ; Depression/immunology ; Enzyme-Linked Immunosorbent Assay ; Epitopes/immunology ; Female ; Fluorescent Antibody Technique, Indirect ; Humans ; Peptides/immunology ; Pregnancy ; Risk Factors
    Chemical Substances Antibodies, Viral ; Antigens, Viral ; Epitopes ; Peptides
    Language English
    Publishing date 2008-09-03
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 0903-465X
    ISSN 0903-465X
    DOI 10.1111/j.1600-0463.2008.00m17.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top