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  1. Article ; Online: Systems Anesthesiology: A New Conceptual Framework.

    Kain, Zeev N

    Anesthesia and analgesia

    2022  Volume 135, Issue 4, Page(s) 671–672

    MeSH term(s) Anesthesiology
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Research Support, N.I.H., Extramural ; Editorial ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Anesthesiology Meets the Metaverse.

    Kain, Zeev N / Cannesson, Maxime P

    Anesthesia and analgesia

    2024  Volume 138, Issue 3, Page(s) 488–490

    MeSH term(s) Anesthesiology
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Editorial
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The intersection of pediatric anesthesiology and social determinants of health.

    Martin, Sarah R / Kain, Zeev N

    Current opinion in anaesthesiology

    2024  Volume 37, Issue 3, Page(s) 271–276

    Abstract: Purpose of review: There is increasing evidence of racial and ethnic disparities in pediatric perioperative care, which indicates a need to identify factors driving disparities. Social determinants of health (SDOH) play a fundamental role in pediatric ... ...

    Abstract Purpose of review: There is increasing evidence of racial and ethnic disparities in pediatric perioperative care, which indicates a need to identify factors driving disparities. Social determinants of health (SDOH) play a fundamental role in pediatric health and are recognized as key underlying mechanisms of healthcare inequities. This article summarizes recent research exploring the influence of SDOH on pediatric perioperative outcomes.
    Recent findings: Despite the scarcity of research exploring SDOH and pediatric perioperative outcomes, recent work demonstrates an association between SDOH and multiple outcomes across the perioperative care continuum. Measures of social disadvantage were associated with preoperative symptom severity, longer hospital stays, and higher rates of postoperative complications and mortality. In some studies, these adverse effects of social disadvantage persisted even when controlling for medical comorbidities and clinical severity.
    Summary: The existing literature offers compelling evidence of the impact of SDOH on perioperative outcomes in children and reveals a critical area in pediatric anesthesia that necessitates further exploration and action. To improve outcomes and address care inequities, future efforts should prioritize the integration of SDOH assessment into pediatric perioperative research and practice.
    MeSH term(s) Humans ; Social Determinants of Health ; Child ; Anesthesiology ; Healthcare Disparities ; Perioperative Care/methods ; Perioperative Care/standards ; Pediatrics/methods ; Pediatrics/statistics & numerical data ; Pediatrics/trends ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Anesthesia/adverse effects ; Anesthesia/methods ; Length of Stay/statistics & numerical data
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645203-6
    ISSN 1473-6500 ; 0952-7907
    ISSN (online) 1473-6500
    ISSN 0952-7907
    DOI 10.1097/ACO.0000000000001367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Fueling Healing: Tackling Challenges in Integrating Nutrition Screening and Therapy Into Perioperative Care in the United States.

    Hung, Isaac / Wischmeyer, Paul E / Kain, Zeev N

    Anesthesia and analgesia

    2024  

    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006766
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  5. Article ; Online: Is Industry- Versus Government-Sponsored Research a Zero-Sum Game?

    Kain, Zeev N / Tsai, Mitchel / Browne, James

    Anesthesia and analgesia

    2023  Volume 136, Issue 6, Page(s) 1052–1054

    MeSH term(s) Industry ; Government ; Drug Industry
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Is Industry- Versus Government-Sponsored Research a Zero-Sum Game?

    Kain, Zeev N / Tsai, Mitchel / Browne, James

    The Journal of arthroplasty

    2023  Volume 38, Issue 6, Page(s) 984–985

    MeSH term(s) Humans ; Industry ; Government ; Drug Industry
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2023.02.017
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  7. Article ; Online: Language barriers and pain disparities in pediatric emergency settings: A call for action.

    Lim, Paulina S / Fortier, Michelle A / Bender, Miriam / Campos, Belinda / Heyming, Theodore / Kain, Zeev N

    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

    2024  

    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1329813-6
    ISSN 1553-2712 ; 1069-6563
    ISSN (online) 1553-2712
    ISSN 1069-6563
    DOI 10.1111/acem.14894
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    Zs.A 4479: Show issues Location:
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  8. Article ; Online: Response to: Does Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction.

    Walls, Halle R / Thomas, Evelyn S / Kain, Zeev N / Schlechter, John A

    Journal of pediatric orthopedics

    2023  Volume 44, Issue 2, Page(s) e209–e210

    MeSH term(s) Child ; Humans ; Adolescent ; Bupivacaine ; Narcotics ; Pain, Postoperative/drug therapy ; Anterior Cruciate Ligament Reconstruction ; Peripheral Nerves ; Anesthetics, Local ; Femoral Nerve ; Anterior Cruciate Ligament Injuries
    Chemical Substances Bupivacaine (Y8335394RO) ; Narcotics ; Anesthetics, Local
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604642-3
    ISSN 1539-2570 ; 0271-6798
    ISSN (online) 1539-2570
    ISSN 0271-6798
    DOI 10.1097/BPO.0000000000002538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1681: Show issues Location:
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  9. Article ; Online: Does Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction.

    Walls, Halle R / Thomas, Evelyn S / Kain, Zeev N / Schlechter, John A

    Journal of pediatric orthopedics

    2023  Volume 43, Issue 8, Page(s) 511–515

    Abstract: Background: Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. This study sought to determine whether liposomal bupivacaine injectable suspension admixture administered as a single-shot adductor canal ... ...

    Abstract Background: Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. This study sought to determine whether liposomal bupivacaine injectable suspension admixture administered as a single-shot adductor canal peripheral nerve block (SPNB+BL) would decrease utilization of at-home opioid analgesics after anterior cruciate ligament reconstruction (ACLR) in adolescents compared with single-shot peripheral nerve block with bupivacaine (SPNB+B) alone.
    Methods: Consecutive ACLR patients with or without meniscal surgery by a single surgeon were enrolled. All received a preoperative single-shot adductor canal peripheral nerve block with either admixture of liposomal bupivacaine injectable suspension with 0.25% bupivacaine (SPNB+BL) or 0.25% bupivacaine alone (SPNB+B). Postoperative pain management included cryotherapy, oral acetaminophen, and ibuprofen. A prescription for 10 doses of hydrocodone/acetaminophen (5/325 mg) was provided in a sealed envelope with instructions to only use in the case of uncontrolled pain. Pain using the visual analog scale; number of consumed narcotics, acetaminophen, ibuprofen, and pain treatment satisfaction for the first 3 postoperative days were recorded. Statistical analysis was performed.
    Results: Fifty-eight patients were enrolled, the average age was 15±1.5 years (SPNB+B=32 patients, SPNB+BL=26 patients). Forty-seven patients (81%) did not require home opioids postoperatively. A significantly lower proportion of patients in the SPNB+BL group required opioids compared with control patients (7.7% vs. 28.1%, P =0.048). Average opioid use was 2 morphine milligram equivalents (MME), 0.4 pills (range, 0 to 20 MME). There were no differences in the visual analog scale or pain treatment satisfaction scores, other demographics, or other operative data. Inverse probability of treatment weighting analysis that was performed to account for any potential group differences revealed home opioid use between groups is significantly different ( P <0.001).
    Conclusions: Liposomal bupivacaine injectable suspension admixture administered as an adductor canal nerve block in adolescents undergoing ACLR effectively reduces home opioid usage postoperatively compared with bupivacaine alone.
    Level of evidence: Level II-prospective comparative study.
    MeSH term(s) Humans ; Adolescent ; Child ; Bupivacaine/therapeutic use ; Narcotics ; Analgesics, Opioid/therapeutic use ; Acetaminophen/therapeutic use ; Anesthetics, Local/therapeutic use ; Pain, Postoperative/drug therapy ; Ibuprofen/therapeutic use ; Prospective Studies ; Analgesics ; Anterior Cruciate Ligament Reconstruction ; Peripheral Nerves
    Chemical Substances Bupivacaine (Y8335394RO) ; Narcotics ; Analgesics, Opioid ; Acetaminophen (362O9ITL9D) ; Anesthetics, Local ; Ibuprofen (WK2XYI10QM) ; MME (78185-58-7) ; Analgesics
    Language English
    Publishing date 2023-07-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604642-3
    ISSN 1539-2570 ; 0271-6798
    ISSN (online) 1539-2570
    ISSN 0271-6798
    DOI 10.1097/BPO.0000000000002466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Anesthesiologists and Hospitalists in Perioperative Care: Together We Are Stronger.

    Pfeifer, Kurt / Ahn, Kyle / Kain, Zeev N

    Anesthesia and analgesia

    2022  Volume 134, Issue 3, Page(s) 463–465

    MeSH term(s) Anesthesiologists ; Hospitalists ; Humans ; Perioperative Care
    Language English
    Publishing date 2022-02-16
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000005891
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