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  1. Article ; Online: Parental Stress in NICU: Where Communication is the Key!

    Kainth, Deepika / Thukral, Anu

    Indian journal of pediatrics

    2023  Volume 91, Issue 1, Page(s) 5

    MeSH term(s) Humans ; Infant, Newborn ; Intensive Care Units, Neonatal ; Parents ; Stress, Psychological ; Communication
    Language English
    Publishing date 2023-07-29
    Publishing country India
    Document type Editorial
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04778-4
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    Zs.A 826: Show issues Location:
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  2. Article ; Online: 'Sad Man' Facies in a Preterm Neonate with Staphylococcal Scalded Skin Syndrome.

    Prakash, Satya / Kainth, Deepika

    Indian journal of pediatrics

    2023  

    Language English
    Publishing date 2023-11-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04953-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 826: Show issues Location:
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  3. Article: Fragility Index of Recently Published Meta-Analyses in Pediatric Urology: A Striking Observation.

    Anand, Sachit / Kainth, Deepika

    Cureus

    2021  Volume 13, Issue 7, Page(s) e16225

    Abstract: Background and objective Fragility Index (FI) of meta-analyses determines their stability in terms of the level of confidence and strength behind the results depicted by them. The present study was conducted to estimate the FI of recently published meta- ... ...

    Abstract Background and objective Fragility Index (FI) of meta-analyses determines their stability in terms of the level of confidence and strength behind the results depicted by them. The present study was conducted to estimate the FI of recently published meta-analyses in the Journal of Pediatric Urology (JPUrol). Method Twenty recently published articles on meta-analyses were screened to identify the eligible ones. The baseline data of each meta-analysis including the details of the author, number of included studies, total sample size, the total number of events, the status of the overall outcome (significant or non-significant), type of effect measure, type of method used for pooling the estimates, and type of effects model were recorded. FI was calculated by doing each single status modification. The 95% CI of the treatment effect was re-calculated until the statistical significance of the meta-analysis was reversed. Results A total of seven articles incorporating 22 meta-analyses were included. Seven (32%) of them had a statistically significant outcome prior to FI estimation. The risk ratio (17/22; 77%) was the most commonly used effect measure. The random-effects model (15/22; 68%) and the Mantel-Haenszel method (20/22; 91%) of pooling the estimates were utilized in the majority of meta-analyses. The median (Q1-Q3; range) FI of statistically significant, non-significant, and total meta-analyses were 5 (3-19.5; 2-39), 5 (3.5-6; 1-17), and 5 (3-13; 1-39) respectively. FI of ≤5 was noticed in four out of seven (57%), 9/15 (60%), and 13/22 (59%) of these meta-analyses respectively. Conclusion Based on our findings, the majority of the recently published meta-analyses in the field of pediatric urology are fragile and depend upon the event status of ≤5 participants.
    Language English
    Publishing date 2021-07-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.16225
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  4. Article ; Online: Intraoperative Regional Cerebral Oxygenation During Pediatric Thoracoscopic Surgery: A Systematic Review.

    Prasad, Gaurav / Singh, Apoorv / Kainth, Deepika / Khanna, Puneet / Anand, Sachit

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2023  Volume 34, Issue 3, Page(s) 274–279

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Child ; Humans ; Infant, Newborn ; Esophageal Atresia/surgery ; Hernias, Diaphragmatic, Congenital/surgery ; Lung/surgery ; Retrospective Studies ; Thoracoscopy/methods ; Tracheoesophageal Fistula/surgery ; Treatment Outcome ; Infant ; Child, Preschool ; Intraoperative Period ; Oxygen/analysis
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-10-20
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2023.0228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3246: Show issues Location:
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  5. Article ; Online: Questions about the HELIX trial.

    Kainth, Deepika / Sharma, Akash / Sankar, Mari Jeeva

    The Lancet. Global health

    2021  Volume 9, Issue 12, Page(s) e1652

    Language English
    Publishing date 2021-11-19
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2723488-5
    ISSN 2214-109X ; 2214-109X
    ISSN (online) 2214-109X
    ISSN 2214-109X
    DOI 10.1016/S2214-109X(21)00492-7
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  6. Article ; Online: A Hyperalert Newborn.

    Kainth, Deepika / Kathiresan, Preethy / Bhad, Roshan / Rao, Ravindra / Verma, Ankit

    NeoReviews

    2022  Volume 23, Issue 6, Page(s) e413–e415

    MeSH term(s) Humans ; Infant, Newborn ; Infant, Newborn, Diseases
    Language English
    Publishing date 2022-07-04
    Publishing country United States
    Document type Journal Article
    ISSN 1526-9906
    ISSN (online) 1526-9906
    DOI 10.1542/neo.23-6-e413
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  7. Article ; Online: Impact of preservation of the azygos vein during surgical repair of esophageal atresia-tracheoesophageal fistula (EA-TEF): a systematic review and meta-analysis.

    Kainth, Deepika / Anand, Sachit / Singh, Apoorv / Bajpai, Minu

    Pediatric surgery international

    2021  Volume 37, Issue 8, Page(s) 983–989

    Abstract: Esophageal atresia-tracheoesophageal fistula (EA-TEF) is one of the common congenital anomalies occurring in newborns. Over the last eight decades, various technical modifications have been proposed in the surgical repair of EA-TEF. Preservation of ... ...

    Abstract Esophageal atresia-tracheoesophageal fistula (EA-TEF) is one of the common congenital anomalies occurring in newborns. Over the last eight decades, various technical modifications have been proposed in the surgical repair of EA-TEF. Preservation of azygos vein is one such modification that has gained considerable attention. However, a consensus statement regarding the superiority of its preservation over its division is lacking. We aim to compare the outcomes of surgery between the two groups of newborns, i.e., those undergoing repair with and without azygos vein preservation, in terms of its complications. The authors systematically searched the databases PubMed, EMBASE, Web of Science, and Scopus through December 2020. The incidence of anastomotic complications and chest infection was compared among the two groups of newborns, i.e., those undergoing surgical repair with (group A) and without azygos vein preservation (group B). Statistical analysis was performed using a fixed-effects model, and pooled risk ratio (RR) and heterogeneity (I
    Language English
    Publishing date 2021-04-27
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-021-04913-2
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2138: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Prevention of fogging inside safety goggles for healthcare professionals during COVID-19 pandemic: A low-cost solution in resource-limited settings.

    Singh, Apoorv / Kainth, Deepika / Anand, Sachit / Mitra, Aparajita

    Tropical doctor

    2021  Volume 51, Issue 3, Page(s) 433–434

    Abstract: Fogging inside the safety goggles is a common problem experienced by more healthcare professionals during the COVID-19 pandemic than ever. Various anti-fogging remedies are available on the market. We have adopted a low-cost alternative that can be ... ...

    Abstract Fogging inside the safety goggles is a common problem experienced by more healthcare professionals during the COVID-19 pandemic than ever. Various anti-fogging remedies are available on the market. We have adopted a low-cost alternative that can be extremely useful in resource-limited settings.
    MeSH term(s) COVID-19/prevention & control ; Delivery of Health Care ; Eye Protective Devices/standards ; Humans ; Occupational Exposure/prevention & control ; Pandemics/prevention & control ; SARS-CoV-2
    Language English
    Publishing date 2021-03-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/0049475521997597
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    Zs.A 1056: Show issues Location:
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  9. Article ; Online: Short-Duration Prednisolone in Children with Nephrotic Syndrome Relapse: A Noninferiority Randomized Controlled Trial.

    Kainth, Deepika / Hari, Pankaj / Sinha, Aditi / Pandey, Shivam / Bagga, Arvind

    Clinical journal of the American Society of Nephrology : CJASN

    2021  Volume 16, Issue 2, Page(s) 225–232

    Abstract: Background and objectives: In children with nephrotic syndrome, steroids are the cornerstone of therapy for relapse. The adequate duration and dosage of steroids, however, have not been an active area of research, especially in children with ... ...

    Abstract Background and objectives: In children with nephrotic syndrome, steroids are the cornerstone of therapy for relapse. The adequate duration and dosage of steroids, however, have not been an active area of research, especially in children with infrequently relapsing nephrotic syndrome. This study investigated the efficacy of an abbreviated regimen for treatment of a relapse in this population.
    Design, setting, participants, & measurements: In a single-center, open-label, randomized controlled trial, we evaluated the efficacy of prednisolone as a "short regimen" (40 mg/m
    Results: A total of 117 patients were enrolled and randomized to short (55) or standard (62) regimen. Fourteen (24%) patients in standard regimen and 12 (23%) in short regimen developed frequent relapses or steroid dependence over a period of 1 year (risk difference, -1%; 95% confidence interval, -15 to 16;
    Conclusions: In children with infrequently relapsing nephrotic syndrome, a short steroid treatment for relapse resulted in a similar proportion of patients developing frequent relapses or steroid dependence; however, noninferiority of a short regimen was not established.
    Clinical trial registry name and registration number: CTRI/2015/11/006345.
    MeSH term(s) Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/adverse effects ; Child ; Child, Preschool ; Female ; Humans ; Male ; Nephrotic Syndrome/drug therapy ; Prednisolone/administration & dosage ; Prednisolone/adverse effects ; Prospective Studies ; Recurrence ; Time Factors
    Chemical Substances Anti-Inflammatory Agents ; Prednisolone (9PHQ9Y1OLM)
    Language English
    Publishing date 2021-01-21
    Publishing country United States
    Document type Comparative Study ; Equivalence Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.06140420
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    Zs.A 6584: Show issues Location:
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  10. Article: Utility of Ischemia-Modified Albumin as a Biomarker for Acute Appendicitis: A Systematic Review and Meta-Analysis.

    Singh, Apoorv / Pogorelić, Zenon / Agrawal, Aniket / Muñoz, Carlos Martin Llorente / Kainth, Deepika / Verma, Ajay / Jindal, Bibekanand / Agarwala, Sandeep / Anand, Sachit

    Journal of clinical medicine

    2023  Volume 12, Issue 17

    Abstract: Background: Acute appendicitis is a frequently encountered surgical emergency. Despite several scoring systems, the possibility of delayed diagnosis persists. In addition, a delayed diagnosis leads to an increased risk of complicated appendicitis. Hence, ...

    Abstract Background: Acute appendicitis is a frequently encountered surgical emergency. Despite several scoring systems, the possibility of delayed diagnosis persists. In addition, a delayed diagnosis leads to an increased risk of complicated appendicitis. Hence, there is a need to identify biological markers to help clinicians rapidly and accurately diagnose and prognosticate acute appendicitis with a high sensitivity and specificity. Although several markers have been evaluated, the pressing concern is still the low specificity of these markers. One such marker is serum ischemia-modified albumin (IMA), which can be a novel biomarker for accurately diagnosing and prognosticating acute appendicitis.
    Methods: The authors conducted a systematic search of the PubMed, EMBASE, Web of Science, and Scopus databases through February 2023 as per the PRISMA guidelines. The difference in the levels of IMA between patients with acute appendicitis vs. healthy controls, and the difference in the levels of IMA between patients with complicated vs. non-complicated acute appendicitis were taken as the outcome measures. Statistical analysis was performed using a random effects model and mean difference (MD) was calculated. The methodological quality of the studies was assessed by utilizing the Newcastle-Ottawa scale.
    Results: A total of six prospective comparative studies were included in the meta-analysis. The analysis revealed that the mean level of serum IMA was significantly raised in the acute appendicitis group (MD 0.21, 95% CI 0.05 to 0.37,
    Conclusions: Serum IMA is a viable potential marker for diagnosing and prognosticating acute appendicitis. However, due to the limited methodological quality of available studies, further prospectively designed and adequately powered studies are needed.
    Language English
    Publishing date 2023-08-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12175486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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