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  1. Article: Spontaneous Bladder Rupture in a Catatonic Schizophrenia Patient.

    Miyakoshi, Megumi / Arai, Takayuki / Kurose, Shin / Kaji, Masataka / Nakane, Jun / Onaya, Mitsumoto / Koreki, Akihiro

    Case reports in psychiatry

    2023  Volume 2023, Page(s) 4277372

    Abstract: Catatonia is a psychiatric emergency in schizophrenia that often leads to excessive activation of the sympathetic nervous system. Urinary retention in catatonia is often underestimated but has potentially detrimental consequences. Herein, we present the ... ...

    Abstract Catatonia is a psychiatric emergency in schizophrenia that often leads to excessive activation of the sympathetic nervous system. Urinary retention in catatonia is often underestimated but has potentially detrimental consequences. Herein, we present the case of a woman in her 40s with schizophrenia treated for catatonia during a relapse. When treated as an inpatient, the patient suddenly complained of severe abdominal pain. Computed tomography revealed a spontaneous rupture of the posterior wall of the bladder, requiring emergency repair surgery in the urology department. The patient was readmitted to our hospital following surgery and ultimately discharged 1 month later. Bladder rupture is life-threatening, and delayed diagnosis and treatment can be fatal. This case report serves as a warning that psychiatrists should not overlook urinary retention in patients with catatonia and should consider bladder rupture in the differential diagnosis when these patients have abdominal pain.
    Language English
    Publishing date 2023-11-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2629914-8
    ISSN 2090-6838 ; 2090-682X
    ISSN (online) 2090-6838
    ISSN 2090-682X
    DOI 10.1155/2023/4277372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Resting-state hyperperfusion in the whole brain: A case of malignant catatonia that improved with electric convulsion therapy.

    Kurose, Shin / Koreki, Akihiro / Funayama, Michitaka / Takahashi, Eriko / Kaji, Masataka / Ogyu, Kamiyu / Takasu, Shotaro / Koizumi, Teruki / Suzuki, Hisaomi / Onaya, Mitsumoto / Mimura, Masaru

    Schizophrenia research

    2019  Volume 210, Page(s) 287–288

    MeSH term(s) Brain/diagnostic imaging ; Brain/physiopathology ; Catatonia/etiology ; Catatonia/physiopathology ; Catatonia/therapy ; Cerebrovascular Circulation/physiology ; Electroconvulsive Therapy ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Schizophrenia/complications ; Schizophrenia/physiopathology ; Schizophrenia/therapy
    Language English
    Publishing date 2019-06-06
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2019.05.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Identification of potential biomarkers of lymph node metastasis in oral squamous cell carcinoma by cDNA microarray analysis.

    Nagata, Masaki / Fujita, Hajime / Ida, Hiroko / Hoshina, Hideyuki / Inoue, Tatsuo / Seki, Yukie / Ohnishi, Makoto / Ohyama, Tokio / Shingaki, Susumu / Kaji, Masataka / Saku, Takashi / Takagi, Ritsuo

    International journal of cancer

    2003  Volume 106, Issue 5, Page(s) 683–689

    Abstract: We surveyed the expression of 557 cancer-related genes in 15 cases of well-differentiated OSCC by cDNA microarray analysis. To identify potential biomarkers for lymph node metastasis, all microarray data were compared by the Mann-Whitney test and the ... ...

    Abstract We surveyed the expression of 557 cancer-related genes in 15 cases of well-differentiated OSCC by cDNA microarray analysis. To identify potential biomarkers for lymph node metastasis, all microarray data were compared by the Mann-Whitney test and the significance analysis of microarrays between OSCCs with and those without lymph node metastasis. The tissues of OSCCs with lymph node metastasis exhibited increased expression levels of MMP-1, MMP-3, uPA, integrin-alpha3, paxillin, tenascin C and IL-6 transcripts. All of these genes were included in common clusters on the Cluster/TreeView analysis, implying that functional gene groups of proteolytic enzymes and integrin-related molecules are involved in cervical lymph node metastasis. The results of RTQ-PCR for differentially expressed genes were in accord with those of cDNA microarray analyses, suggesting that the data obtained by microarray gene expression analyses were valid. Consistent with cooperative expression patterns, immunohistochemical analyses demonstrated that products of MMP-1, MMP-3 and uPA were colocalized to components of the neoplastic stroma, particularly mononuclear inflammatory cells with well-developed eosinophilic cytoplasm. Our results suggest that expression levels of molecules involved in tissue remodeling and cell-ECM adhesion, especially MMP-1 and integrin-alpha3, can provide an accurate biomarker system for predicting the risk of cervical lymph node metastasis in OSCC.
    MeSH term(s) Biomarkers, Tumor/genetics ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/secondary ; DNA Primers ; DNA, Neoplasm/analysis ; Gene Expression Profiling ; Humans ; Lymphatic Metastasis ; Mouth Neoplasms/genetics ; Mouth Neoplasms/pathology ; Neck Dissection ; Neoplasm Proteins/genetics ; Oligonucleotide Array Sequence Analysis/methods ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Neoplasm/genetics ; RNA, Neoplasm/metabolism ; Reverse Transcriptase Polymerase Chain Reaction
    Chemical Substances Biomarkers, Tumor ; DNA Primers ; DNA, Neoplasm ; Neoplasm Proteins ; RNA, Messenger ; RNA, Neoplasm
    Language English
    Publishing date 2003-09-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218257-9
    ISSN 1097-0215 ; 0020-7136
    ISSN (online) 1097-0215
    ISSN 0020-7136
    DOI 10.1002/ijc.11283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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