Article ; Online: Bariatric Nutritional Intervention in Obese Patients with Compensated Liver Cirrhosis: A Four-Year Prospective Study.
Digestive diseases and sciences
2024 Volume 69, Issue 4, Page(s) 1467–1478
Abstract: Background: Obesity and liver cirrhosis represent significant health challenges, often leading to various complications.: Aims: This prospective study aimed to investigate the impact of a four-year bariatric intervention, focusing on adherence to the ...
| Abstract | Background: Obesity and liver cirrhosis represent significant health challenges, often leading to various complications. Aims: This prospective study aimed to investigate the impact of a four-year bariatric intervention, focusing on adherence to the Mediterranean Diet, on anthropometric, hematologic, and biochemical parameters in obese patients with compensated liver cirrhosis. Additionally, the study evaluated the concurrent contribution of weight loss to these health indicators. Methods: The study involved 62 patients with compensated liver cirrhosis (mean age 65.87 ± 6 years) and 44 healthy controls (mean age 59.11 ± 8 years), all with a BMI > 30 kg/m Results: Anthropometric parameters, including weight, BMI, waist and hip circumference, percentage of fat mass, and handgrip strength, exhibited significant improvements (p < 0.05), particularly within the first year of the intervention. Liver function tests and lipid profiles of the patients also showed significant enhancements (p < 0.05). Hematological and biochemical indices, such as hematocrit and ferritin, experienced discreet improvements in the patient cohort (p < 0.05). Conclusions: This study highlights the potential of a structured bariatric intervention rooted in the Mediterranean diet to positively influence the health of obese patients with compensated liver cirrhosis. The observed improvements in anthropometric, biochemical, and hematologic parameters, particularly within the first year of the intervention, suggest the importance of dietary modifications in managing the health of this patient population. |
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| MeSH term(s) | Humans ; Middle Aged ; Aged ; Prospective Studies ; Hand Strength ; Body Mass Index ; Obesity/epidemiology ; Liver Cirrhosis ; Weight Loss ; Bariatrics | |||||
| Language | English | |||||
| Publishing date | 2024-02-27 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 304250-9 | |||||
| ISSN | 1573-2568 ; 0163-2116 | |||||
| ISSN (online) | 1573-2568 | |||||
| ISSN | 0163-2116 | |||||
| DOI | 10.1007/s10620-023-08223-6 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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