LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 131

Search options

  1. Book: Local delivery of cytoreductive agents for the treatment of glioblastoma

    Kalkanis, Steven N.

    (Neuro-oncology ; 17, Suppl. 2)

    2015  

    Author's details physician ed.: Steven N. Kalkanis
    Series title Neuro-oncology ; 17, Suppl. 2
    Neuro-Oncology
    Collection Neuro-Oncology
    Language English
    Size ii36 S. : Ill., graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Cary, NC
    Publishing country United States
    Document type Book
    HBZ-ID HT018645022
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

  2. Article ; Online: Presidential Address to the 2021 Annual Meeting of the Congress of Neurological Surgeons.

    Kalkanis, Steven N

    Neurosurgery

    2022  Volume 68, Issue Suppl 1, Page(s) 1–5

    MeSH term(s) Humans ; Neurosurgeons ; Neurosurgery ; Societies, Medical
    Language English
    Publishing date 2022-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1227/NEU.0000000000001881
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Introduction. Update on brain metastases.

    Aghi, Manish K / Brastianos, Priscilla K / Kim, Albert H / Kalkanis, Steven N / Tonn, Joerg-Christian

    Neurosurgical focus

    2023  Volume 55, Issue 2, Page(s) E1

    MeSH term(s) Humans ; Brain Neoplasms/surgery ; Brain Neoplasms/secondary ; Radiosurgery
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2026589-X
    ISSN 1092-0684 ; 1092-0684
    ISSN (online) 1092-0684
    ISSN 1092-0684
    DOI 10.3171/2023.6.FOCUS23343
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: The AANS/CNS Section on Tumors: a summary of 40 years of advocacy to advance the care of patients with brain and spine tumors.

    Parney, Ian F / Warnick, Ronald E / Lang, Frederick F / Rutka, James T / Kalkanis, Steven / Glick, Roberta / Rosenblum, Mark L / Germano, Isabelle M

    Journal of neurosurgery

    2024  , Page(s) 1–7

    Abstract: The AANS/CNS Section on Tumors was founded 40 years ago in 1984 to assist in the education of neurosurgeons interested in neuro-oncology, and serves as a resource for other national organizations regarding the clinical treatment of nervous system tumors. ...

    Abstract The AANS/CNS Section on Tumors was founded 40 years ago in 1984 to assist in the education of neurosurgeons interested in neuro-oncology, and serves as a resource for other national organizations regarding the clinical treatment of nervous system tumors. The Section on Tumors was the first national physicians' professional organization dedicated to the study and treatment of patients with brain and spine tumors. Over the past 40 years, the Section on Tumors has built solid foundations, including establishing the tumor section satellite meetings, founding the Journal of Neuro-Oncology (the first medical journal dedicated to brain and spine surgical oncology), advancing surgical neuro-oncology education and research, promoting neurosurgical involvement in neuro-oncology clinical trials, and advocating for patients with brain and spine tumors. This review provides a synopsis of the Section on Tumors' history, its challenges, and its opportunities, drawing on the section's archives and input from the 17 section chairs who led it during its first 40 years.
    Language English
    Publishing date 2024-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3089-2
    ISSN 1933-0693 ; 0022-3085
    ISSN (online) 1933-0693
    ISSN 0022-3085
    DOI 10.3171/2023.12.JNS232781
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Setting the stage: local delivery of cytoreductive agents for the treatment of glioblastoma.

    Kalkanis, Steven N

    Neuro-oncology

    2015  Volume 17 Suppl 2, Page(s) ii1–ii2

    MeSH term(s) Antineoplastic Agents/therapeutic use ; Brain Neoplasms/drug therapy ; Drug Delivery Systems ; Glioblastoma/drug therapy ; Humans
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2015-03
    Publishing country England
    Document type Introductory Journal Article
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/nov001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Treatment of Adults With Metastatic Brain Tumors: Executive Summary.

    Olson, Jeffrey J / Kalkanis, Steven N / Ryken, Timothy C

    Neurosurgery

    2019  Volume 84, Issue 3, Page(s) 550–552

    Abstract: Background: The Congress of Neurological Surgeons systematic review and evidence-based clinical practice parameter guidelines for the treatment of adults with metastatic brain tumors was first published in 2010. Because of the time elapsed since that ... ...

    Abstract Background: The Congress of Neurological Surgeons systematic review and evidence-based clinical practice parameter guidelines for the treatment of adults with metastatic brain tumors was first published in 2010. Because of the time elapsed since that publication, an update of this set of guidelines based on literature published since is now indicated.
    Objective: To establish the best evidence-based management of metastatic brain tumors over all commonly used diagnostic and treatment modalities in regularly encountered clinical situations.
    Methods: Literature searches regarding management of metastatic brain tumors with whole brain radiation therapy, surgery, stereotactic radiosurgery, chemotherapy, prophylactic anticonvulsants, steroids, instances of multiple brain metastases, and emerging and investigational therapies were carried out to answer questions designed by consensus of a multidisciplinary writing group.
    Results: Recommendations were created and their strength linked to the quality of the literature data available thus creating an evidence-based guideline. Importantly, shortcomings and biases to the literature data are brought out so as to provide guidance for future investigation and improvements in the management of patients with metastatic brain tumors.
    Conclusion: This series of guidelines was constructed to assess the most current and clinically relevant evidence for management of metastatic brain tumors. They set a benchmark regarding the current evidence base for this management while also highlighting important key areas for future basic and clinical research, particularly on those topics for which no recommendations could be formulated.The full guideline can be found at: https://www.cns.org/guidelines-treatment-adults-metastatic-brain-tumors/chapter_1.
    MeSH term(s) Adult ; Brain Neoplasms/secondary ; Brain Neoplasms/surgery ; Congresses as Topic/standards ; Consensus ; Evidence-Based Medicine/standards ; Female ; Humans ; Male ; Neurosurgeons/standards ; Radiosurgery ; Therapies, Investigational
    Language English
    Publishing date 2019-01-10
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyy540
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: The CNS Mission and NEUROSURGERY® Publications.

    Shupak, Regina / Rao, Ganesh / Kalkanis, Steven N

    Neurosurgery

    2019  Volume 85, Issue 4, Page(s) 439–440

    Language English
    Publishing date 2019-09-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyz317
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Laser interstitial thermal therapy for deep-seated perivascular brain tumors is not associated with distal ischemia.

    Reese, Jared C / Fadel, Hassan A / Pawloski, Jacob A / Samir, Mariam / Haider, Sameah / Komatar, Ricardo J / Luther, Evan / Morell, Alexis A / Ivan, Mike E / Robin, Adam M / Kalkanis, Steven N / Lee, Ian Y

    Journal of neuro-oncology

    2024  Volume 166, Issue 2, Page(s) 265–272

    Abstract: Purpose: Laser interstitial thermal therapy (LITT) is a minimally invasive cytoreductive treatment option for brain tumors with a risk of vascular injury from catheter placement or thermal energy. This may be of concern with deep-seated tumors that have ...

    Abstract Purpose: Laser interstitial thermal therapy (LITT) is a minimally invasive cytoreductive treatment option for brain tumors with a risk of vascular injury from catheter placement or thermal energy. This may be of concern with deep-seated tumors that have surrounding end-artery perforators and critical microvasculature. The purpose of this study was to assess the risk of distal ischemia following LITT for deep-seated perivascular brain tumors.
    Methods: A retrospective review of a multi-institution database was used to identify patients who underwent LITT between 2013 and 2022 for tumors located within the insula, thalamus, basal ganglia, and anterior perforated substance. Demographic, clinical and volumetric tumor characteristics were collected. The primary outcome was radiographic evidence of distal ischemia on post-ablation magnetic resonance imaging (MRI).
    Results: 61 LITT ablations for deep-seated perivascular brain tumors were performed. Of the tumors treated, 24 (39%) were low-grade gliomas, 32 (52%) were high-grade gliomas, and 5 (8%) were metastatic. The principal location included 31 (51%) insular, 14 (23%) thalamic, 13 (21%) basal ganglia, and 3 (5%) anterior perforated substance tumors. The average tumor size was 19.6 cm
    Conclusion: We demonstrate that LITT for deep-seated perivascular brain tumors has minimal ischemic risks and is a feasible cytoreductive treatment option for otherwise difficult to access intracranial tumors.
    MeSH term(s) Humans ; Laser Therapy/methods ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/surgery ; Glioma/surgery ; Magnetic Resonance Imaging/methods ; Retrospective Studies ; Lasers
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604875-4
    ISSN 1573-7373 ; 0167-594X
    ISSN (online) 1573-7373
    ISSN 0167-594X
    DOI 10.1007/s11060-023-04546-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: COVID-19 in the hotspot of Metropolitan Detroit: A multi-faceted health system experience.

    Gifford, Linda / Johnson, Christine C / Haque, Nadia / Passalacqua, Karla D / Swiderek, Jennifer / Kalkanis, Steven

    The International journal of health planning and management

    2021  Volume 37, Issue 2, Page(s) 657–672

    Abstract: Health systems were abruptly plunged into a crisis as SARS-CoV-2 exploded into a pandemic in spring 2020. In March-April 2020, Metropolitan Detroit was a US "hotspot." As a large health system with five hospitals and two behavioural health inpatient ... ...

    Abstract Health systems were abruptly plunged into a crisis as SARS-CoV-2 exploded into a pandemic in spring 2020. In March-April 2020, Metropolitan Detroit was a US "hotspot." As a large health system with five hospitals and two behavioural health inpatient facilities, a health insurance company, a medical group and physician network, and 41 ambulatory clinics normally hosting over 10,000 daily patient encounters, the Henry Ford Health System deployed numerous strategies in the management of this upheaval. As hospitals and Emergency Departments were inundated with COVID-19 patients, other services and activities needed to shut down as state-mandated policies were promulgated, new internal and external communication networks established, and management of employees and resources such as ventilators, ICU beds, personal protective equipment, and laboratory supplies became critical challenges. We describe herein the system-wide strategies implemented and lessons learned in the operation of a health system in the initial throes of a global pandemic.
    MeSH term(s) COVID-19 ; Humans ; Pandemics ; Personal Protective Equipment ; SARS-CoV-2 ; Ventilators, Mechanical
    Language English
    Publishing date 2021-12-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 632786-2
    ISSN 1099-1751 ; 0749-6753
    ISSN (online) 1099-1751
    ISSN 0749-6753
    DOI 10.1002/hpm.3392
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Treatment of Adults With Vestibular Schwannomas: Executive Summary.

    Olson, Jeffrey J / Kalkanis, Steven N / Ryken, Timothy C

    Neurosurgery

    2018  Volume 82, Issue 2, Page(s) 129–134

    Abstract: Background: Vestibular schwannomas (VS) are uncommon lesions that are a substantial challenge to the neurosurgeons, otologists, and radiation oncologists who undertake their clinical management. A starting point to improving the current knowledge is to ... ...

    Abstract Background: Vestibular schwannomas (VS) are uncommon lesions that are a substantial challenge to the neurosurgeons, otologists, and radiation oncologists who undertake their clinical management. A starting point to improving the current knowledge is to define the benchmarks of the current research studying VS management using evidence-based techniques in order to allow meaningful points of departure for future scientific and clinical research.
    Objective: To establish the best evidence-based management of VS, including initial otologic evaluation, imaging diagnosis, use of surgical techniques, assessment of tumor pathology, and the administration of radiation therapy.
    Methods: Multidisciplinary writing groups were identified to design questions, literature searches, and collection and classification of relevant findings. This information was then translated to recommendations based on the strength of the available literature.
    Results: This guideline series yielded some level 2 recommendations and a greater number of level 3 recommendations directed at the management of VS. Importantly, in some cases, a number of well-designed questions and subsequent searches did not yield information that allowed creation of a meaningful and justifiable recommendation.
    Conclusion: This series of guidelines was constructed to assess the most current and clinically relevant evidence for the management of VS. They set a benchmark regarding the current evidence base for this type of tumor while also highlighting important key areas for future basic and clinical research, particularly on those topics for which no recommendations could be formulated.  The full guidelines can be found at: https://www.cns.org/guidelines/guidelines-management-patients-vestibular-schwannoma.
    MeSH term(s) Adult ; Guidelines as Topic ; Humans ; Neuroma, Acoustic/therapy ; Systematic Reviews as Topic
    Language English
    Publishing date 2018-02-05
    Publishing country United States
    Document type Introductory Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyx586
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top