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  1. Article: Short Latency Radiation Induced Osteosarcoma Detected on

    Gill, Sana Munir / Hassan, Aamna / Asghar, Namra / Ahmad, Usman / Kalsoom Awan, Umm E / Niazi, Imran Khalid

    Molecular imaging and radionuclide therapy

    2022  Volume 31, Issue 1, Page(s) 66–68

    Abstract: ... ...

    Abstract 18
    Language English
    Publishing date 2022-02-03
    Publishing country Turkey
    Document type Journal Article
    ISSN 2146-1414
    ISSN 2146-1414
    DOI 10.4274/mirt.galenos.2020.26566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Baseline Characteristics, Prognostic Factors, and Treatment Outcomes for Adult Patients With Rhabdomyosarcoma (RMS).

    Rab, Saif Ur / Bin Naeem, Sameen / Baloch, Naqib Ullah / Jhatial, Mussadique Ali / Waheed, Muhammad / Fasih, Samir / Kalsoom Awan, Umm-E

    Cureus

    2022  Volume 14, Issue 12, Page(s) e32961

    Abstract: Background: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood, while in adults it is one of the rarer tumors. Its prognosis is better in children with current treatment modalities; however, it carries poorer prognosis in adults. ...

    Abstract Background: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood, while in adults it is one of the rarer tumors. Its prognosis is better in children with current treatment modalities; however, it carries poorer prognosis in adults. Recent data on adult RMS is scarce from our part of world. We report outcomes of adult patients with RMS, and with 40 patients; it is the first study to publish such a large data from Pakistan.
    Methods: This was a retrospective study that included 64 adult patients aged 18 years and older. After data extraction and scrutiny, a total of 40 patients were segregated with diagnosis of RMS of various varieties who were treated and followed up subsequently. International Business Machines (IBM) Statistical Package for Social Sciences (SPSS), version 26 (IBM Corp., Armonk, NY) was used to evaluate all of the gathered data.
    Results: Embryonal RMS (ERMS) was the most common subtype. Factors favoring better overall survival (OS) at 5 years were absence of nodal and distal metastases, treatment with surgery, margin negative resection, and absence of residual disease on postoperative imaging. Adjuvant radiation therapy (XRT) for positive resection margins as well as for residual disease on postoperative imaging also favored better OS at 5 years. Chemotherapy did impart a trend towards better OS; however, it was not significant. Histopathologic subtype and tumor size did not have any significant impact on outcomes. Median progression free survival (PFS) was 11 months and median OS was 15 months.
    Conclusions: Adult RMS is a rare disease entity with widely heterogeneous clinical picture and poorer outcomes as compared to the disease of childhood and adolescence. Further prospective studies with larger sample size are required to establish role of patient, disease, and treatment-related factors affecting outcomes in our population.
    Language English
    Publishing date 2022-12-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.32961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: An Unusual Occurrence of Uterine Metastases in a Case of Invasive Ductal Breast Carcinoma.

    Azhar, Musa / Hamdani, Syed Abdul Mannan / Iftikhar, Jhanzeb / Ahmad, Waqas / Mushtaq, Sajid / Kalsoom Awan, Umm-E

    Cureus

    2021  Volume 13, Issue 11, Page(s) e19820

    Abstract: Breast cancer is the most frequent cancer in women and has a high proclivity for metastasizing, yet it seldom affects gynaecological organs. We present a case of invasive ductal carcinoma of the breast that metastasized to the uterus following initial ... ...

    Abstract Breast cancer is the most frequent cancer in women and has a high proclivity for metastasizing, yet it seldom affects gynaecological organs. We present a case of invasive ductal carcinoma of the breast that metastasized to the uterus following initial curative treatment. Our patient was taking tamoxifen, which can induce endometrial hyperplasia and make diagnosis more complicated.
    Language English
    Publishing date 2021-11-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.19820
    Database MEDical Literature Analysis and Retrieval System OnLINE

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