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  1. Article: Fontan-associated liver disease.

    Hilscher, Moira B / Kamath, Patrick S

    Clinical liver disease

    2023  Volume 22, Issue 4, Page(s) 130–133

    Language English
    Publishing date 2023-06-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2657644-2
    ISSN 2046-2484
    ISSN 2046-2484
    DOI 10.1097/CLD.0000000000000061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Portopulmonary hypertension: May we agree to disagree?

    Krowka, Michael J / Kamath, Patrick S

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2023  Volume 29, Issue 4, Page(s) 349–350

    MeSH term(s) Humans ; Liver Transplantation ; Liver Diseases ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/etiology ; Hypertension, Pulmonary/therapy
    Language English
    Publishing date 2023-02-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1097/LVT.0000000000000078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Chronic liver failure

    Ginès, Pere / Kamath, Patrick S. / Arroyo, Vicente

    mechanisms and management

    (Clinical gastroenterology)

    2011  

    Author's details ed. by Pere Ginès ; Patrick S. Kamath ; Vicente Arroyo
    Series title Clinical gastroenterology
    Language English
    Size XVIII, 588 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016601544
    ISBN 978-1-60761-865-2 ; 9781607618669 ; 1-60761-865-6 ; 1607618664
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Lung Infection in Severe Alcohol-related Hepatitis: Not to be Underestimated.

    Gonzalez, Stevan A / Kamath, Patrick S

    The American journal of gastroenterology

    2022  Volume 117, Issue 7, Page(s) 1044–1045

    MeSH term(s) Hepatitis, Alcoholic/complications ; Humans ; Lung ; Pneumonia
    Language English
    Publishing date 2022-06-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000001864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Pharmacotherapies for Portal Hypertension: Current Status and Expanding Indications.

    Elfeki, Mohamed A / Singal, Ashwani K / Kamath, Patrick S

    Current hepatology reports

    2023  Volume 22, Issue 1, Page(s) 44–50

    Abstract: Purpose: Non-selective beta blockers remain pharmacotherapy of choice for prevention of first episode of variceal bleeding (primary prevention) and for prevention of its recurrence after initial hemostasis (secondary prophylaxis). This review will ... ...

    Abstract Purpose: Non-selective beta blockers remain pharmacotherapy of choice for prevention of first episode of variceal bleeding (primary prevention) and for prevention of its recurrence after initial hemostasis (secondary prophylaxis). This review will update the current and emerging pharmacological therapies for portal hypertension.
    Recent findings: Data have emerged on carvedilol in preventing hepatic decompensation and improving patient survival among patients with clinically significant portal hypertension. Because measurement of WHVP is invasive and not feasible in routine practice, non-invasive tests with liver stiffness measurement in combination with platelet count may be accurate in identifying clinically significant portal hypertension.
    Summary: Carvedilol is more effective in reducing portal pressure compared to nadolol or propranolol. Its use has expanded to reduce risk of hepatic decompensation among patients with CSPH, which can be identified non-invasively using liver stiffness and platelet count. Studies are needed on non-invasive biomarkers to guide and optimize pharmacological treatment of portal hypertension.
    Language English
    Publishing date 2023-02-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2813071-6
    ISSN 2195-9595 ; 2195-9595 ; 1540-3416
    ISSN (online) 2195-9595
    ISSN 2195-9595 ; 1540-3416
    DOI 10.1007/s11901-023-00600-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Should patients with acute-on-chronic liver failure grade 3 receive higher priority for liver transplantation?

    Artru, Florent / Goldberg, David / Kamath, Patrick S

    Journal of hepatology

    2023  Volume 78, Issue 6, Page(s) 1118–1123

    Abstract: In this debate, the authors consider whether patients with acute-on-chronic liver failure grade 3 (ACLF-3) should receive higher liver transplant priority, with reference to the following clinical case: a 62-year-old male with a history of decompensated ... ...

    Abstract In this debate, the authors consider whether patients with acute-on-chronic liver failure grade 3 (ACLF-3) should receive higher liver transplant priority, with reference to the following clinical case: a 62-year-old male with a history of decompensated alcohol-associated cirrhosis, with recurrent ascites and hepatic encephalopathy, and metabolic comorbidities (type 2 diabetes mellitus, arterial hypertension and a BMI of 31 kg/m
    MeSH term(s) Male ; Humans ; Middle Aged ; Acute-On-Chronic Liver Failure/diagnosis ; Acute-On-Chronic Liver Failure/etiology ; Acute-On-Chronic Liver Failure/surgery ; Liver Transplantation ; Hepatic Encephalopathy/complications ; Diabetes Mellitus, Type 2/complications ; Prognosis ; Liver Cirrhosis/complications ; Severity of Illness Index ; Retrospective Studies
    Language English
    Publishing date 2023-05-12
    Publishing country Netherlands
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2022.12.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Liver Cirrhosis and Portal Hypertension: How to Deal with Esophageal Varices?

    Jothimani, Dinesh / Rela, Mohamed / Kamath, Patrick S

    The Medical clinics of North America

    2023  Volume 107, Issue 3, Page(s) 491–504

    Abstract: The understanding of pathogenesis of portal hypertension in patients with liver cirrhosis continues to evolve. In addition to progressive fibrosis, cirrhosis is characterized by parenchymal extinction and vascular remodelling, causing architectural ... ...

    Abstract The understanding of pathogenesis of portal hypertension in patients with liver cirrhosis continues to evolve. In addition to progressive fibrosis, cirrhosis is characterized by parenchymal extinction and vascular remodelling, causing architectural distortion. Existence of prothrombotic state and more recently, intestinal bacterial dysbiosis are recently described in the pathogenesis of portal hypertension. Clinically significant portal hypertension (CSPH) is an important prognostic milestone in patients with liver cirrhosis. This is a pre-symptomatic phase that predicts the development of varices, ascites and importantly increased risk of Hepatocellular carcinoma (HCC). CSPH is associated with significantly reduced survival. Endoscopic surveillance is necessary in these patients. Non-selective Beta-blocker is the preferred therapy for primary prophylaxis in the management of portal hypertension. Patients with acute variceal bleed should be resuscitated appropriately, followed by vasoactive drugs and endoscopic therapy. Early TIPS should be considered in those with refractory bleed or in endoscopic treatment failure. Application of artificial intelligence and machine learning may be useful in future for identifying patients at risk of variceal hemorrhage.
    MeSH term(s) Humans ; Esophageal and Gastric Varices/diagnosis ; Esophageal and Gastric Varices/etiology ; Esophageal and Gastric Varices/therapy ; Carcinoma, Hepatocellular/complications ; Artificial Intelligence ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/therapy ; Liver Neoplasms/complications ; Hypertension, Portal/complications ; Hypertension, Portal/diagnosis ; Hypertension, Portal/therapy ; Liver Cirrhosis/complications
    Language English
    Publishing date 2023-02-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 215710-x
    ISSN 1557-9859 ; 0025-7125
    ISSN (online) 1557-9859
    ISSN 0025-7125
    DOI 10.1016/j.mcna.2023.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A History of the Assessment of Liver Performance.

    Mousa, Omar Y / Kamath, Patrick S

    Clinical liver disease

    2021  Volume 18, Issue Suppl 1, Page(s) 28–48

    Abstract: Content available: Author Interview and Audio Recording. ...

    Abstract Content available: Author Interview and Audio Recording.
    Language English
    Publishing date 2021-10-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2657644-2
    ISSN 2046-2484
    ISSN 2046-2484
    DOI 10.1002/cld.1100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Resolution of Loculated Chylous Ascites Using Intraperitoneal Fibrinolytic Therapy.

    Oblizajek, Nicholas R / Kamath, Patrick S

    Hepatology (Baltimore, Md.)

    2021  Volume 74, Issue 4, Page(s) 2293–2295

    MeSH term(s) Chylous Ascites/diagnosis ; Chylous Ascites/drug therapy ; Chylous Ascites/etiology ; Fibrinolytic Agents/administration & dosage ; Humans ; Infusions, Parenteral/methods ; Lymphatic System/abnormalities ; Lymphatic System/diagnostic imaging ; Lymphography/methods ; Male ; Middle Aged ; Paracentesis/methods ; Risk Adjustment/methods ; Tissue Plasminogen Activator/administration & dosage ; Tomography, X-Ray Computed/methods ; Treatment Outcome ; Ultrasonography/methods
    Chemical Substances Fibrinolytic Agents ; Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2021-06-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1002/hep.31816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Acute on chronic liver failure.

    Kamath, Patrick S

    Clinical liver disease

    2017  Volume 9, Issue 4, Page(s) 86–88

    Language English
    Publishing date 2017-04-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2657644-2
    ISSN 2046-2484
    ISSN 2046-2484
    DOI 10.1002/cld.625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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