LIVIVO - Search results -

Search results

Result 1 - 10 of total 20

Search options

Article ; Online: Methanol Mass Poisoning Outbreak

Kambiz Soltaninejad

The International Journal of Occupational and Environmental Medicine, Vol 11, Iss 3 July, Pp 148-

A Consequence of COVID-19 Pandemic and Misleading Messages on Social Media

2020 Volume 50

Abstract: No abstract available] ...

Abstract	[No abstract available]
Keywords	methanol ; poisoning ; covid-19 ; outbreak ; Industrial medicine. Industrial hygiene ; RC963-969 ; covid19
Language	English
Publishing date	2020-07-01T00:00:00Z
Publisher	National Iranian Oil Company (NIOC) Health Organization
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Outbreak of Mushroom Poisoning in Iran

Kambiz Soltaninejad

The International Journal of Occupational and Environmental Medicine, Vol 9, Iss 3, Pp 152-

April–May, 2018

2018 Volume 156

Abstract: From April 28 to May 28, 2018, more than 1200 patients with impression of mushroom poisoning were referred to hospital emergency departments in 13 west and northwestern provinces, Iran; 112 (8.9%) patients were hospitalized and 19 were expired (ie, a ... ...

Abstract	From April 28 to May 28, 2018, more than 1200 patients with impression of mushroom poisoning were referred to hospital emergency departments in 13 west and northwestern provinces, Iran; 112 (8.9%) patients were hospitalized and 19 were expired (ie, a fatality rate of 1.5%). The outbreak began in Kermanshah province with increasing number of patients presenting with severe abdominal pain, nausea, vomiting, and diarrhea soon after consumption of wild mushrooms. Lepiota brunneioncarnata, Hypholoma fascicalare, and Coprinopsis atramentaria have been involved in this outbreak. To prevent similar outbreaks, raising public awareness about risky behaviors of collecting and consuming wild self-picked mushrooms is of paramount importance. Herein, we present our experience with this outbreak.
Keywords	Mushroom poisoning ; Disease outbreaks ; Epidemics ; Iran ; Industrial medicine. Industrial hygiene ; RC963-969
Language	English
Publishing date	2018-07-01T00:00:00Z
Publisher	National Iranian Oil Company (NIOC) Health Organization
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Tramadol-Induced Organ Toxicity via Oxidative Stress

Leila Mohammadnejad / Kambiz Soltaninejad

International Journal of Medical Toxicology and Forensic Medicine, Vol 12, Iss 1, Pp 35430-

A Review Study

2022 Volume 35430

Abstract: Background: Tramadol (TR) is a synthetic opioid-like centrally acting analgesic used for moderate to severe pain management in various diseases. Numerous investigations have supported the association between tramadol use and increased levels of oxygen- ... ...

Abstract	Background: Tramadol (TR) is a synthetic opioid-like centrally acting analgesic used for moderate to severe pain management in various diseases. Numerous investigations have supported the association between tramadol use and increased levels of oxygen-free radicals. Mass production of reactive oxygen species produces secondary toxic compounds. This could damage the internal components of the cell and ultimately causes organ damage. There exists a growing trend of tramadol abuse and the increasing reports of poisoning, abuse, and mortality due to this drug. Thus, the present study aimed to review the animals and human studies on the effects of acute and chronic exposure of tramadol in inducing organ toxicities through oxidative stress. Methods: Pubmed, Google Scholar, and Scopus bibliographic databases were searched for studies that investigated oxidative stress as a mechanism of toxicity by tramadol. A manual search of reference lists of the retrieved articles was conducted. Data were collected from 2000 to 2021 (up to June 2021). Results: From 28 articles concerning experimental and human studies of TR-induced oxidative stress organ damage, which included in this review, the occurrence of lipid peroxidation, alteration in the levels of total antioxidant capacity, and other oxidative stress biomarkers in many organs such as the brain, liver, kidney, adrenal and lung in the experimental studies of tramadol exposure have been observed. Conclusion: Oxidative stress could be considered the most critical toxic mechanism in TR-induced tissue damage.
Keywords	tramadol ; reactive oxygen species ; oxidative stress ; toxicity ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	500
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Shaheed Beheshti University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Analyzing Toxic Chemical Components in Illegal Alcoholic Beverages

Mahmoud Abbasi / Kambiz Soltaninejad

International Journal of Medical Toxicology and Forensic Medicine, Vol 10, Iss

2020 Volume 3

Abstract: Background: The illegal production of alcoholic beverages, due to the non-standard conditions, increases the risk of producing counterfeit and toxic products. The chemical analysis of toxic components in illegally-produced alcoholic beverages is ... ...

Abstract	Background: The illegal production of alcoholic beverages, due to the non-standard conditions, increases the risk of producing counterfeit and toxic products. The chemical analysis of toxic components in illegally-produced alcoholic beverages is necessary for each country. The present study aimed to identify the existence of methanol and other potentially toxic compounds in the seized illegally-produced alcoholic beverages. Methods: In this descriptive laboratory-based study, we analyzed the toxic chemical components in sized illegally-produced alcoholic beverages, submitted to the Forensic Toxicology Laboratory of the Legal Medicine Center of Markazi Province, Arak City, Iran, in a year. A total of 100 seized illegally-produced alcohol beverage samples were collected. The qualitative and quantitative analysis of ethanol, methanol, 1-propanol, 2-propanol, and acetone was performed by the Gas Chromatography-Flame Ionization Detection (GC–FID) method. Results: Methanol was detected in 6% of the evaluated samples (concentration range:1.2%-12%v/v). Acetone was detected in two of the studied samples (mean concentration: 0.7%v/v), and 2-propanol with a concentration of 0.5%v/v was found in one sample. Besides, ethanol was detected in all explored samples (mean concentration: 24%v/v). Conclusion: Methanol was the main toxic chemical component in illegal alcoholic beverages; thus, it should be considered in public health policy and prevention programs in the country.
Keywords	adulteration ; alcoholic beverages ; chemical analysis ; methanol ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	540
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	Shaheed Beheshti University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Sudden Infant Death Due to Postvaccinal Myocarditis

Babak Salahshour / Sajjad Sadeghi / Ahmad Sajadianfar / Kambiz Soltaninejad

International Journal of Medical Toxicology and Forensic Medicine, Vol 11, Iss 3, p

A Case Report

2021 Volume 32227

Abstract: Background: Vaccination is a fundamental strategy in public health for controlling and eradicating infectious diseases. However, the undesirable Adverse Events Following Immunization (AEFI) should be effectively monitored, prevented, and managed in ... ...

Abstract	Background: Vaccination is a fundamental strategy in public health for controlling and eradicating infectious diseases. However, the undesirable Adverse Events Following Immunization (AEFI) should be effectively monitored, prevented, and managed in societies. Previously, Sudden Infant Death (SID) has been reported as a serious AEFI. We present a rare case of SID in an 18-month-old girl due to severe myocarditis following vaccination. Case Presentation: An 18-month-old girl presented to the Emergency Department (ED) with a history of the injection of Diphtheria-Tetanus-Whole Cell Pertussis (DTwP); Measles, Mumps, and Rubella (MMR), and oral poliovirus vaccines. She expired one-hour post ED admission after the episodes of vomiting and cardiopulmonary arrest. Postmortem histopathological examination signified marked congestion and the destruction of muscle fibers in the myocardium with inflammatory cells infiltration predominantly eosinophils. Given the postmortem histopathological findings, the cause of death was concluded as severe myocarditis following vaccination. Finally, the causality assessment was performed according to the Naranjo scale; the relevant data revealed a probable association in this regard (Naranjo score 6). Conclusion: Myocarditis is a rare and probable AEFI; thus, cardiac monitoring should be recommended as a diagnostic measure in managing postvaccinal adverse effects.
Keywords	vaccine ; death ; myocarditis ; histopathology ; case report ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	610
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	Shaheed Beheshti University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Determining Undeclared Synthetic Pharmaceuticals as Adulterants in Weight Loss Herbal Medicines

Babak Salahshour / Sajjad Sadeghi / Hajar Nazari / Kambiz Soltaninejad

International Journal of Medical Toxicology and Forensic Medicine, Vol 10, Iss 1, p

2020 Volume 26253

Abstract: Background: The popularity and use of herbal medicines and supplements are growing worldwide. Herbal anti-obesity products have been considered as suitable alternatives to synthetic pharmaceuticals as they are introduced as harmless natural products. ... ...

Abstract	Background: The popularity and use of herbal medicines and supplements are growing worldwide. Herbal anti-obesity products have been considered as suitable alternatives to synthetic pharmaceuticals as they are introduced as harmless natural products. However, some manufacturers often add undeclared synthetic pharmaceuticals to the anti-obesity herbal medicine products to improve their efficacy and potency. The present study aimed to analyze herbal weight loss products collected from the drug market in Bojnurd City, Iran. Methods: Ninety-six herbal drug samples, as weight loss products, were obtained from herb shops and pharmacies in Bojnurd City, Iran. All samples were analyzed to detect undeclared active pharmaceutical ingredients using High-Performance Liquid Chromatography with Diode Array Detector (HPLC-DAD) and Gas Chromatography-Mass Spectrometry (GC-MS) techniques. Results: Caffeine, trimethoxyamphetamine, and vitamin E were identified in herbal weight loss products. Caffeine was detected in 21.8% of the obtained samples, as the most common undeclared active pharmaceutical adulterant. Conclusion: Undeclared active pharmaceutical ingredients in herbal weight loss products could threaten patients’ health. Thus, it is necessary to create awareness through health authorities in this regard.
Keywords	adulteration ; caffeine ; trimethoxyamphetamine ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	540
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Shaheed Beheshti University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Ultrasound-Assisted Liquid-Liquid Extraction for Analyzing Methadone in Urine Samples by Gas Chromatography-Mass Spectrometry

Ahmad Shekari / Rooholah Valipour / Mehrdad Setareh / Kambiz Soltaninejad

International Journal of Medical Toxicology and Forensic Medicine, Vol 10, Iss

2020 Volume 3

Abstract: Background: Methadone abuse and dependence are a growing concern in some countries. The present study developed and validated a rapid, simple, easy, and sensitive method for analyzing methadone in urine specimens. This approach was intended for use in ... ...

Abstract	Background: Methadone abuse and dependence are a growing concern in some countries. The present study developed and validated a rapid, simple, easy, and sensitive method for analyzing methadone in urine specimens. This approach was intended for use in clinical and forensic toxicology and drug screening laboratories. Methods: We determined methadone in urine samples by Gas Chromatography / Mass Spectrometry (GC / MS). Besides, we used Ultrasound-Assisted Liquid-Liquid Extraction (UALLE) method for the extraction and preconcentration of methadone before analysis. Results: The detection limit was 2.1 ng/mL and the limit of quantification equaled 7 ng/mL. The methadone calibration curve was linear and ranged from 7 to 10000 ng/mL, and the correlation coefficient was calculated as 0.9984. The tested method was accurate and precise. Recovery fell in the range of 81.3% to 97.4% and the enrichment factor was measured as 8.7. The method was successfully used for determining methadone in real clinical and postmortem urine samples. Conclusion: The presented method was a rapid, easy, simple, and sensitive procedure; thus, it could be applied in clinical and forensic toxicology laboratories as a routine approach for analyzing methadone.
Keywords	gas chromatography-mass spectrometry (gc-ms) ; methadone ; ultrasound-assisted liquid-liquid microextraction ; urine ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	660
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	Shaheed Beheshti University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Clinical and Medicolegal Aspects of Fatal Imidacloprid Deliberate Self-poisoning

Vida Shiri-Ghaleh / Salim Khani / Mehrdad Moradi / Kambiz Soltaninejad

International Journal of Medical Toxicology and Forensic Medicine, Vol 11, Iss 1, p

A Case Report

2021 Volume 32228

Abstract: Background: Imidacloprid is a neonicotinoid insecticide and agonist of nicotinic acetylcholine receptors. Despite its low toxicity profile, there are rare studies on its fatal poisoning. In this report, we described clinical and postmortem findings of a ... ...

Abstract	Background: Imidacloprid is a neonicotinoid insecticide and agonist of nicotinic acetylcholine receptors. Despite its low toxicity profile, there are rare studies on its fatal poisoning. In this report, we described clinical and postmortem findings of a fatal imidacloprid poisoning. Methods: A 33-year-old female presented to the emergency department with a history of deliberate consumption of unknown insecticide. On admission, she was drowsy and hypotensive with tachycardia and miotic pupils. Despite supportive therapy, she continued to be unconscious, with severe metabolic acidosis and developed a cardio-respiratory arrest and expired. Results: A forensic autopsy was performed. The result of the toxicological analysis showed that imidacloprid concentrations were 267.8 µg/mL in femoral blood, 144.5 µg/mL in stomach content, and 292.3 µg/mL in bile. Conclusion: Although imidacloprid is generally less toxic to humans high concentrations in biological samples could be considered lethal. Therefore, the educational programs about its toxicity should be considered for health care providers.
Keywords	imidacloprid ; self-poisoning ; neonicotinoid insecticide ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	Shaheed Beheshti University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Determination of Common Pharmaceutical Adulterants in Herbal Medicinal Products Used in the Treatment of Opioid Addiction

Vida Shiri-Ghaleh / Mehrdad Moradi / Kambiz Soltaninejad

International Journal of Medical Toxicology and Forensic Medicine, Vol 9, Iss 4, Pp 243-

2019 Volume 254

Abstract: Background: Opioid addiction is a serious and growing global concern. Recently, herbal medicine has been popular for the treatment of opioid abusers worldwide. Unfortunately, the adulteration of herbal remedies with undeclared synthetic pharmaceuticals ... ...

Abstract	Background: Opioid addiction is a serious and growing global concern. Recently, herbal medicine has been popular for the treatment of opioid abusers worldwide. Unfortunately, the adulteration of herbal remedies with undeclared synthetic pharmaceuticals has been reported. In Iran, there are few reports on the adulteration of herbal remedies by synthetic pharmaceuticals sold as opioid addiction treatment. The aim of this study was to analyze herbal products used in opioid addiction treatment for the identification of synthetic pharmaceuticals as adulterants in the remedies. Methods: Forty commonly-used handmade herbal products for the treatment of opioid addiction were collected from herbal shops in Kermanshah (western area of Iran). After organoleptic examinations, the samples were prepared and analyzed by high-performance liquid chromatography and gas chromatography-mass spectrometry for detecting probable synthetic pharmaceutical adulterants. Results: The chromatographic analysis of the samples showed that 90% of the products had at least one undeclared pharmaceutical ingredient as an adulterant. The majority of the samples (n=19, 47.5%) had only one undeclared pharmaceutical. Diphenoxylate (n=24, 39.3%), tramadol (n=16, 26.2), methadone (n=8, 13.2%), and the combination of these drugs were reported as common adulterants. We detected the presence of buprenorphine and sildenafil as adulterating agents in the herbal formulations for the first time. Conclusion: According to the presence of undeclared synthetic pharmaceuticals in opioid addiction herbal products, as well as their threats to public health, awareness, in this case, is necessary.
Keywords	herbal medicines ; pharmaceutical adulterants ; opioid addiction ; iran ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	540
Language	English
Publishing date	2019-10-01T00:00:00Z
Publisher	Shaheed Beheshti University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Optimization and Validation of a novel Nebulizer-assisted Liquid Phase Microextraction Followed by HPLC-DAD for Diazinon Analysis in Plasma Samples

Reza Mohammadzaheri / Mehdi Ansari Dogaheh / Maryam Kazemipour / Kambiz Soltaninejad

International Journal of Medical Toxicology and Forensic Medicine, Vol 9, Iss 4, Pp 221-

2019 Volume 232

Abstract: Background: Diazinon is among the most prevalently used broad-spectrum organophosphates insecticides. Diazinon toxicity depends on its blood concentration. The current study aimed to extract and determine diazinon in plasma samples using a new Nebulizer - ...

Abstract	Background: Diazinon is among the most prevalently used broad-spectrum organophosphates insecticides. Diazinon toxicity depends on its blood concentration. The current study aimed to extract and determine diazinon in plasma samples using a new Nebulizer -Assisted Liquid-Phase Microextraction followed by High-Performance Liquid Chromatography with Diode-Array Detection (NALPME-HPLC-DAD). Methods: Several effective parameters, including the type and volume of extracting solvent, pH, surfactant, salt amount, and nebulizing, were evaluated and optimized to find the best condition for the extraction and determination of diazinon in plasma samples using High-Performance Liquid Chromatography with Diode-Array Detection (HPLC-DAD). Additionally, the Plackett-Burman design was employed in preliminary experiments to screen the most appropriate parameters. Furthermore, we selected a central composite design to determine the best experimental conditions in NALPME-HPLC-DAD. Results: In an optimum condition, 412 μL of toluene (as extracting solvent) and nebulizing with nitrogen gas as dispersing and emulsification, sodium lauryl sulfate (2.8% w/v) and 100μL sodium chloride (1.5% w/v) in pH 8.1 were selected. The standard calibration curves for diazinon were linear with the concentration range of 0.5–4 µg/mL with a correlation coefficient of 0.9992. The Limit Of Detection (LOD) and Limit Of Quantification (LOQ) for diazinon were 0.123 µg/mL and 0.372 µg/mL, respectively. Conclusion: The proposed method was simple, accurate, precise, and sensitive for analyzing diazinon in the plasma samples. This method can be used for analyzing plasma diazinon concentrations in acute poisoning cases in clinical and forensic toxicology analyses.
Keywords	diazinon ; nebulizer-assisted liquid phase microextraction ; high-performance liquid chromatograph ; plasma ; determination ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	660
Language	English
Publishing date	2019-10-01T00:00:00Z
Publisher	Shaheed Beheshti University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

Your last searches

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED