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  1. Article ; Online: [What Should Pharmacists Do through the Clinical Research, toward the Community-based Integrated Care Systems? -From the Perspective of Dissemination and Implementation Research].

    Kamei, Miwako / Okada, Hiroshi

    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

    2022  Volume 142, Issue 3, Page(s) 205–206

    MeSH term(s) Attitude of Health Personnel ; Community Pharmacy Services ; Delivery of Health Care, Integrated ; Humans ; Pharmacists ; Professional Role
    Language Japanese
    Publishing date 2022-02-28
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 200514-1
    ISSN 1347-5231 ; 0031-6903 ; 0372-7750 ; 0919-2085 ; 0919-2131
    ISSN (online) 1347-5231
    ISSN 0031-6903 ; 0372-7750 ; 0919-2085 ; 0919-2131
    DOI 10.1248/yakushi.21-00174-F
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 643: Show issues Location:
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  2. Article ; Online: Safety of mirogabalin and pregabalin in Japanese patients with neuropathic pain: a retrospective cohort study.

    Nakajima, Rie / Ooba, Nobuhiro / Kamei, Miwako / Hashiba, Hajime / Miyazaki, Choichiro

    Expert opinion on drug safety

    2023  Volume 22, Issue 9, Page(s) 841–848

    Abstract: Background: Few studies have compared the safety risks between the gabapentinoids, pregabalin, and mirogabalin in post-marketing clinical settings. We assessed reported events associated with gabapentinoid use in patients with neuropathic pain.: ... ...

    Abstract Background: Few studies have compared the safety risks between the gabapentinoids, pregabalin, and mirogabalin in post-marketing clinical settings. We assessed reported events associated with gabapentinoid use in patients with neuropathic pain.
    Research design and methods: We conducted a retrospective cohort study between September 2020 and December 2020 using the community pharmacies records in Japan. The pharmacists identified new vs. prevalent users of mirogabalin and pregabalin in September 2020 and reported data regarding baseline and adverse events to the Japan Pharmaceutical Association using web-based questionnaires. The incidence of events and hazard ratio (HR) were consequently compared.
    Results: New users of mirogabalin and pregabalin were identified (n = 1,650 and 2,244; mean age (SD): 69 (15) and 68 (16) years; women: 59% and 56%, respectively). Although serious events were not reported, a marked difference in HRs of common adverse events, including somnolence (1.6), dizziness (1.3), nausea (2.8), edema (3.1), and acetaminophen (2.0)/antidepressant (2.4) addition, was observed.
    Conclusion: No new serious safety concerns were found for mirogabalin and pregabalin use in patients with neuropathic pain, although the HR of some events indicated increased risk among mirogabalin users. However, further studies are needed as estimates for events occurring in small numbers with wide confidence intervals.
    MeSH term(s) Female ; Humans ; Analgesics/adverse effects ; Analgesics/therapeutic use ; East Asian People ; Neuralgia/drug therapy ; Pregabalin/adverse effects ; Pregabalin/therapeutic use ; Retrospective Studies ; Bridged Bicyclo Compounds/adverse effects ; Bridged Bicyclo Compounds/therapeutic use ; Male ; Middle Aged ; Aged ; Aged, 80 and over
    Chemical Substances Analgesics ; mirogabalin (S7LK2KDM5U) ; Pregabalin (55JG375S6M) ; Bridged Bicyclo Compounds
    Language English
    Publishing date 2023-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2088728-0
    ISSN 1744-764X ; 1474-0338
    ISSN (online) 1744-764X
    ISSN 1474-0338
    DOI 10.1080/14740338.2023.2193395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Factors Associated with Medication Non-Adherence among Patients with Lifestyle-Related Non-Communicable Diseases.

    Nakajima, Rie / Watanabe, Fumiyuki / Kamei, Miwako

    Pharmacy (Basel, Switzerland)

    2021  Volume 9, Issue 2

    Abstract: This cross-sectional study explored the association between medication non-adherence and its factors in patients with non-communicable diseases (NCDs) using an online structured questionnaire emailed to 30,000 people (aged over 20 years who lived in ... ...

    Abstract This cross-sectional study explored the association between medication non-adherence and its factors in patients with non-communicable diseases (NCDs) using an online structured questionnaire emailed to 30,000 people (aged over 20 years who lived in Japan at the time of the survey). The questions concerned respondents' characteristics, medication non-adherence, health beliefs, lifestyles, and trouble taking medication. Factors related to non-adherence were analyzed among patients with lifestyle-related NCDs categorized into two age groups: 20-59, and >60 years. Unintentional (
    Language English
    Publishing date 2021-04-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737194-3
    ISSN 2226-4787 ; 2226-4787
    ISSN (online) 2226-4787
    ISSN 2226-4787
    DOI 10.3390/pharmacy9020090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comparative study of preciseness in the regional variation of influenza in Japan among the National Official Sentinel Surveillance of Infectious Diseases and the National Database of Electronic Medical Claims.

    Ohkusa, Yasushi / Sugawara, Tamie / Takahashi, Kenzo / Kamei, Miwako

    Bioscience trends

    2019  Volume 12, Issue 6, Page(s) 636–640

    Abstract: In Japan, national official surveillance for influenza has been performed at about 5,000 sentinel hospitals/clinics by the National Official Sentinel Surveillance of Infectious Diseases (NOSSID). Meanwhile, all electronic medical claims nationwide in the ...

    Abstract In Japan, national official surveillance for influenza has been performed at about 5,000 sentinel hospitals/clinics by the National Official Sentinel Surveillance of Infectious Diseases (NOSSID). Meanwhile, all electronic medical claims nationwide in the National Database of Electronic Medical Claims (NDBEMC) were recently disclosed by the Ministry of Health, Labour and Welfare of Japan. We compared the regional variation of influenza incidence among prefectures between the NOSSID and NDBEMC. The data were extracted from NOSSID and the NDBEMC for the 2010/2011 through 2013/2014 seasons. We compared the data of both datasets season by season by using Spearman's rank correlation in each season. Spearman's rank correlation values for the four seasons were 0.7823, 0.3907, 0.4961 and 0.4543, and their p-values were less than 0.00005, 0.0066, 0.0004 and 0.0013, respectively. Statistically, regional variation of influenza incidence in NOSSID is not imprecise, but its correlation with the NDBEMC dataset is not so high. It is important to note this fact when interpreting regional variation in NOSSID.
    MeSH term(s) Administrative Claims, Healthcare ; Age Distribution ; Databases, Factual ; Hospitals/statistics & numerical data ; Humans ; Incidence ; Influenza, Human/epidemiology ; Japan ; Seasons ; Sentinel Surveillance ; Sex Distribution
    Language English
    Publishing date 2019-01-23
    Publishing country Japan
    Document type Comparative Study ; Journal Article
    ZDB-ID 2543899-2
    ISSN 1881-7823 ; 1881-7815
    ISSN (online) 1881-7823
    ISSN 1881-7815
    DOI 10.5582/bst.2018.01279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Prescription surveillance for early detection system of emerging and reemerging infectious disease outbreaks.

    Sugawara, Tamie / Ohkusa, Yasushi / Kawanohara, Hirokazu / Kamei, Miwako

    Bioscience trends

    2018  Volume 12, Issue 5, Page(s) 523–525

    Abstract: Based on prescriptions filled at external pharmacies, prescription surveillance (PS) in Japan has been reporting the estimated numbers of influenza and varicella patients and people prescribed certain drugs since 2009. Every morning, this system ... ...

    Abstract Based on prescriptions filled at external pharmacies, prescription surveillance (PS) in Japan has been reporting the estimated numbers of influenza and varicella patients and people prescribed certain drugs since 2009. Every morning, this system estimates the numbers of patients from the numbers of prescriptions filled nationwide for neuraminidase inhibitors, anti-herpes virus drugs, antibiotic drugs, antipyretic analgesics, and multi-ingredient cold medications. Moreover, it can detect "unexplained" infectious diseases that are not explained as infectious diseases monitored by other surveillance systems. Such "unexplained" infectious diseases might be emerging and re-emerging infectious diseases including bioterrorism attacks, which are reportedly difficult to diagnose, at least in early outbreak stages. To ascertain the system's potential benefits, this study examined schemes to detect "unexplained" infectious diseases using PS information. The numbers of patients prescribed the respective drugs are first regressed on the known infectious diseases, time trends, and dummies for day-of-the-week, holidays, and days following a holiday. Known infectious diseases are defined as covered by the National Official Sentinel Surveillance for Infectious Diseases under the Infection Control Law. After the numbers of patients from PS are compared with the predicted numbers of patients, their probabilities of occurrence are calculated. We examined the system's prospective operation from January 2017 through July 2018. The criterion we used to define aberrations varied, from 0.01 to 10
    MeSH term(s) Antiviral Agents/therapeutic use ; Chickenpox/drug therapy ; Chickenpox/epidemiology ; Clinical Pharmacy Information Systems ; Communicable Diseases/epidemiology ; Communicable Diseases, Emerging/epidemiology ; Data Collection ; Disease Outbreaks ; Humans ; Infectious Disease Medicine ; Influenza, Human/drug therapy ; Influenza, Human/epidemiology ; Japan/epidemiology ; Pharmaceutical Preparations ; Pharmacies ; Population Surveillance ; Prospective Studies ; Time Factors
    Chemical Substances Antiviral Agents ; Pharmaceutical Preparations
    Language English
    Publishing date 2018-11-25
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2543899-2
    ISSN 1881-7823 ; 1881-7815
    ISSN (online) 1881-7823
    ISSN 1881-7815
    DOI 10.5582/bst.2018.01201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Evaluation of the global action plan on antimicrobial resistance in Japan during its first eighteen months.

    Ohkusa, Yasushi / Sugawara, Tamie / Kawanohara, Hirokazu / Kamei, Miwako

    Drug discoveries & therapeutics

    2018  Volume 12, Issue 3, Page(s) 182–184

    Abstract: Antimicrobial resistance (AMR) has garnered the most attention among public health concerns worldwide. Japan formulated a national action plan for AMR in April 2016. The plan seeks to reduce the amount of antimicrobials used in 2020 to two-thirds of the ... ...

    Abstract Antimicrobial resistance (AMR) has garnered the most attention among public health concerns worldwide. Japan formulated a national action plan for AMR in April 2016. The plan seeks to reduce the amount of antimicrobials used in 2020 to two-thirds of the use recorded in 2013. Prescription surveillance (PS) is being used to monitor trends in the amount of antimicrobials used. PS estimates the number of patients prescribed an antimicrobial each day. The number of patients who were prescribed an antimicrobial under the action plan was analyzed by including dummy variables with other control variables. Data from April 1, 2011 to 30 September 30, 2017 were analyzed. When the number of patients with an infectious disease (1 of 13 specified diseases) served as a dummy variable, estimates indicated that the coefficient of that dummy variable was not significant. If the number of patients with an infectious disease (1 of 13 specified diseases) was excluded as an explanatory variable, then the estimated coefficient was significant. The global action plan in Japan might not reduce the amount of antimicrobials used. The current results indicated that the number of patients who were prescribed an antimicrobial did not decrease significantly after initiation of the action plan. This finding does not exclude the possibility that the average amount of antimicrobials used per patient has decreased.
    MeSH term(s) Anti-Infective Agents/therapeutic use ; Drug Resistance, Microbial ; Humans ; Japan ; Practice Patterns, Physicians'/trends ; Program Evaluation ; Public Health
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2018-08-10
    Publishing country Japan
    Document type Journal Article
    ISSN 1881-7831
    ISSN 1881-7831
    DOI 10.5582/ddt.2018.01011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Welfare analysis of a zero-smoking policy - A case study in Japan.

    Nakamura, Yuuki / Takahashi, Kenzo / Nomura, Marika / Kamei, Miwako

    Drug discoveries & therapeutics

    2018  Volume 12, Issue 1, Page(s) 37–41

    Abstract: Smoking cessation efforts in Japan reduce smoking rates. A future zero-smoking policy would completely prohibit smoking (0% rate). We therefore analyzed the social welfare of smokers and non-smokers under a hypothetical zero-smoking policy. The demand ... ...

    Abstract Smoking cessation efforts in Japan reduce smoking rates. A future zero-smoking policy would completely prohibit smoking (0% rate). We therefore analyzed the social welfare of smokers and non-smokers under a hypothetical zero-smoking policy. The demand curve for smoking from 1990 to 2014 was estimated by defining quantity as the number of cigarettes smoked and price as total tobacco sales/total cigarettes smoked by the two-stage least squares method using the tax on tobacco as the instrumental variable. In the estimation equation (calculated using the ordinary least squares method), the price of tobacco was the dependent variable and tobacco quantity the explanatory variable. The estimated constant was 31.90, the estimated coefficient of quantity was - 0.0061 (both, p < 0.0004), and the determinant coefficient was 0.9187. Thus, the 2015 consumer surplus was 1.08 trillion yen (US$ 9.82 billion) (95% confidence interval (CI), 889 billion yen (US$ 8.08 billion) - 1.27 trillion yen (US$ 11.6 billion)). Because tax revenue from tobacco in 2011 was 2.38 trillion yen (US$ 21.6 billion), the estimated deadweight loss if smoking were prohibited in 2014 was 3.31 trillion yen (US$ 30.2 billion) (95% CI, 3.13 trillion yen (US$ 28.5 billion) - 3.50 trillion yen (US$ 31.8 billion)), representing a deadweight loss about 0.6 trillion yen (US$ 5.45 billion) below the 2014 disease burden (4.10-4.12 trillion yen (US$ 37.3-37.5 billion)). We conclude that a zero-smoking policy would improve social welfare in Japan.
    MeSH term(s) Commerce ; Health Policy ; Humans ; Japan/epidemiology ; Least-Squares Analysis ; Smoking/economics ; Smoking/epidemiology ; Smoking Prevention/legislation & jurisprudence ; Social Welfare/legislation & jurisprudence ; Tobacco Products/statistics & numerical data
    Language English
    Publishing date 2018-02-25
    Publishing country Japan
    Document type Journal Article
    ISSN 1881-7831
    ISSN 1881-7831
    DOI 10.5582/ddt.2017.01062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: [Adherence to Oral Antihyperglycemic Agents (Dipeptidyl Peptidase-4 Inhibitors and Biguanides) and Its Associated Factors in Patients with Type 2 Diabetes].

    Hayashi, Ai / Kubo, Takekazu / Okuyama, Kotoba / Tokita, Shigeru / Kamei, Miwako

    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

    2019  Volume 139, Issue 12, Page(s) 1569–1581

    Abstract: To investigate medication adherence to oral antihyperglycemic agents and its associated factors in Japanese type 2 diabetic patients, a questionnaire survey was conducted in 983 adult patients receiving once-daily (QD) or twice-daily (BID) dipeptidyl ... ...

    Abstract To investigate medication adherence to oral antihyperglycemic agents and its associated factors in Japanese type 2 diabetic patients, a questionnaire survey was conducted in 983 adult patients receiving once-daily (QD) or twice-daily (BID) dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitor) or BID biguanides (BG) as monotherapy at 502 pharmacies in Japan. The percentage of patients with good adherence (the proportion of days in which patients took all pills as prescribed in the past 7 days ≥80%) was high (≥90%) in any dosing regimen with no significant difference among the groups. The following factors were identified as associating with good adherence: the longer duration of type 2 diabetes (≥1 year) (p=0.002), "Feeling your disease gets worse if you don't take medications" (p=0.031), "Not forgetting to bring along your medicine when you leave home" (p=0.007), "Feeling anxiety on taking medications for long period of time" (p=0.042), "Neither feeling nor not feeling anxiety on taking medications for a long period of time" (p=0.004), "Never run out of your medicine because you get a refill on time" (p=0.035), and the lower MMAS-4 score (p<0.001). Subgroup analyses revealed that adherence of younger patients (<65 years) with BG (BID) was lower than those with DPP-4 inhibitor (QD) (p=0.021). Additionally, around 60% of patients currently prescribed with QD preferred QD regimen, and ≥80% patients prescribed with BID equally preferred once-weekly or QD regimen, suggesting a large discrepancy exists between their preference and the actual regimen in patients on BID.
    MeSH term(s) Administration, Oral ; Adult ; Aged ; Anxiety ; Biguanides/administration & dosage ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/psychology ; Dipeptidyl-Peptidase IV Inhibitors/administration & dosage ; Female ; Humans ; Hypoglycemic Agents/administration & dosage ; Male ; Medication Adherence/statistics & numerical data ; Middle Aged ; Young Adult
    Chemical Substances Biguanides ; Dipeptidyl-Peptidase IV Inhibitors ; Hypoglycemic Agents
    Language Japanese
    Publishing date 2019-11-13
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 200514-1
    ISSN 1347-5231 ; 0031-6903 ; 0372-7750 ; 0919-2085 ; 0919-2131
    ISSN (online) 1347-5231
    ISSN 0031-6903 ; 0372-7750 ; 0919-2085 ; 0919-2131
    DOI 10.1248/yakushi.18-00197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 643: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Article ; Online: Validation of a Reorganized Training Program Using a Cognitive Behavioral Therapy Approach to Enable Community Pharmacists to Provide Empathic Patient Counseling.

    Tanuma, Kazunori / Watanabe, Fumiyuki / Maeda, Hatsuyo / Saitoh, Nobutaka / Kamei, Miwako

    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

    2018  Volume 139, Issue 1, Page(s) 97–106

    Abstract: To enable community pharmacists to provide empathic patient counseling, we developed and validated a training program based on the cognitive behavioral therapy approach (CBT-A) in our previous study. The major focus points of the re-structured training ... ...

    Abstract To enable community pharmacists to provide empathic patient counseling, we developed and validated a training program based on the cognitive behavioral therapy approach (CBT-A) in our previous study. The major focus points of the re-structured training program were "inclusion of basic communication skills", "exemplifying correspondence involving CBT-A using pre-recorded video(VTR)", and "approach methods for cases where counter-evidence is unavailable". The training program lasted for 4 h per day, for a total of 8 h. We also performed role-play scenarios on information gathering and medication guidance for simulated patients before and after training, and evaluated patient satisfaction with counseling, patient counseling alliance scores, and the degrees of the psychological distance between patients and pharmacists. Participants had high satisfaction with the discussion and role-play aspects of the training, as in our previous study. Participants also showed high satisfaction with "exemplifying correspondence involving CBT-A using VTR". Counseling time was significantly longer when using CBT-A compared to ordinary information gathering and medication guidance, but patient satisfaction and patient counseling alliance scores were both higher, and the psychological distance between patient and pharmacist was lower. Accordingly, if patients cannot solve their own problems, even when pharmacists provide polite responses and expertise, patients can be guided in their problem solving using CBT-A. It suggested that using CBT-A could solve the problem of patients with anxiety due to problems that cannot be solved only via drug-centered approach.
    MeSH term(s) Anxiety ; Clinical Competence ; Cognitive Behavioral Therapy ; Communication ; Counseling ; Education, Pharmacy/methods ; Empathy ; Female ; Humans ; Male ; Patient Satisfaction ; Patients/psychology ; Personal Satisfaction ; Pharmacists/psychology ; Professional-Patient Relations
    Language English
    Publishing date 2018-12-31
    Publishing country Japan
    Document type Journal Article ; Validation Studies
    ZDB-ID 200514-1
    ISSN 1347-5231 ; 0031-6903 ; 0372-7750 ; 0919-2085 ; 0919-2131
    ISSN (online) 1347-5231
    ISSN 0031-6903 ; 0372-7750 ; 0919-2085 ; 0919-2131
    DOI 10.1248/yakushi.18-00115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: [Learning outcomes of six-year pharmaceutical education program].

    Nakamura, Akihiro / Hasegawa, Yoichi / Kamei, Miwako

    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

    2015  Volume 135, Issue 3, Page(s) 331–332

    MeSH term(s) Education, Pharmacy ; Learning ; Time Factors
    Language Japanese
    Publishing date 2015
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 200514-1
    ISSN 1347-5231 ; 0031-6903 ; 0372-7750 ; 0919-2085 ; 0919-2131
    ISSN (online) 1347-5231
    ISSN 0031-6903 ; 0372-7750 ; 0919-2085 ; 0919-2131
    DOI 10.1248/yakushi.14-00206-F
    Database MEDical Literature Analysis and Retrieval System OnLINE

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