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  1. Article ; Online: Public Awareness of Medical Research Terminology in Japan, and the Accuracy of Physicians' Predictions regarding that Awareness.

    Kamisato, Ayako / Hong, Hyunsoo / Okubo, Suguru

    Asian bioethics review

    2023  Volume 15, Issue 4, Page(s) 397–416

    Abstract: One of the ethical principles of medical research involving human subjects is obtaining proper informed consent (IC). However, if the participants' actual awareness of medical research terminology is lower than the researchers' prediction of that ... ...

    Abstract One of the ethical principles of medical research involving human subjects is obtaining proper informed consent (IC). However, if the participants' actual awareness of medical research terminology is lower than the researchers' prediction of that awareness, it may cause difficulty obtaining proper IC. Therefore, this study aims to clarify the presence of "perception gaps" and then discuss IC-related issues and measures based on the insights obtained. We conducted two online surveys: a "public survey" to understand the Japanese public's awareness of 11 medical research terms and a "physicians' survey" to investigate physicians' predictions regarding public awareness. In the "public survey," for each term, respondents were instructed to select their situation from "understand," "have heard," or "have never heard." In the "physicians' survey," respondents were asked to estimate the proportions of the general public who would "have understood," "have heard," or "have never heard" by using an 11-step scale. We analyzed separately in two age groups to understand the age-related difference. We received 1002 valid responses for the "public survey" and 275 for the "physicians' survey." Of the public respondents, more than 80% had never heard of terms such as
    Supplementary information: The online version contains supplementary material available at 10.1007/s41649-023-00247-4.
    Language English
    Publishing date 2023-03-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2602378-7
    ISSN 1793-9453 ; 1793-8759
    ISSN (online) 1793-9453
    ISSN 1793-8759
    DOI 10.1007/s41649-023-00247-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Attitudes towards human fetal tissue research: Survey of researchers and the public in Japan.

    Yui, Hideki / Kamisato, Ayako / Muto, Kaori / Yashiro, Yoshimi / Watanabe, Saori / Kiya, Yukitaka / Fujisawa, Kumiko / Inoue, Yusuke / Yamagata, Zentaro

    Regenerative therapy

    2023  Volume 24, Page(s) 78–84

    Abstract: Introduction: The rules for human fetal tissue (HFT) research in Japan are unclear.: Methods: In this paper, we conducted a web survey to examine the attitudes of Japanese researchers (n=535) and the public (n=3,000) toward HFT research.: Results: ...

    Abstract Introduction: The rules for human fetal tissue (HFT) research in Japan are unclear.
    Methods: In this paper, we conducted a web survey to examine the attitudes of Japanese researchers (n=535) and the public (n=3,000) toward HFT research.
    Results: The results demonstrated that 5.8% of researchers and 18.8% of the public explicitly opposed HFT research, and 71.8% of the researchers thought that the rules for HFT research need to be clarified. Even among researchers who intended to consider conducting HFT research, 74.2% responded that the rules should be clarified. Although different from attitudes to make decisions regarding HFT donation, being non-religious and in their reproductive age among women in the public group were factors for accepting attitudes toward HFT research.
    Conclusion: To establish the rules, it is necessary to develop a system that can adequately protect vulnerable women who are asked to provide HFT.
    Language English
    Publishing date 2023-06-13
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2835333-X
    ISSN 2352-3204 ; 2352-3204
    ISSN (online) 2352-3204
    ISSN 2352-3204
    DOI 10.1016/j.reth.2023.05.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Concerns in Methodology for Self-Administered Questionnaire: Needs for Involvement of Social Scientists.

    Masuda, Takahiro / Uchimido, Ryo / Nosaka, Nobuyuki / Akiyama, Hiroko / Kamisato, Ayako / Yoshida, Masayuki

    Chest

    2021  Volume 160, Issue 1, Page(s) e92–e93

    MeSH term(s) Humans ; Needs Assessment ; Surveys and Questionnaires
    Language English
    Publishing date 2021-07-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.02.076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui III Zs.45: Show issues Location:
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  4. Article ; Online: Comparison of the 2021 International Society for Stem Cell Research (ISSCR) guidelines for "laboratory-based human stem cell research, embryo research, and related research activities" and the corresponding Japanese regulations.

    Yui, Hideki / Muto, Kaori / Yashiro, Yoshimi / Watanabe, Saori / Kiya, Yukitaka / Kamisato, Ayako / Inoue, Yusuke / Yamagata, Zentaro

    Regenerative therapy

    2022  Volume 21, Page(s) 46–51

    Abstract: This paper presents a comparison of the 2021 guidelines for stem cell research and clinical translation outlined by the International Society for Stem Cell Research (ISSCR) with the current regulations in Japan regarding the performance of such research. ...

    Abstract This paper presents a comparison of the 2021 guidelines for stem cell research and clinical translation outlined by the International Society for Stem Cell Research (ISSCR) with the current regulations in Japan regarding the performance of such research. This paper provides a convenient English-language summary of the Japanese regulations, and illustrates the difference between the ISSCR guidelines and Japanese regulations regarding the conditions of implementation of study activities using human embryos or stem cells, for researchers outside Japan. The regulations governing the performance of research activities using human embryos or stem cells in Japan are relatively complex and comprise a range of laws and guidelines; the specific rules applied depend on the characteristics of each study. Therefore, even similar research activities may differ in terms of not only the guidelines or laws implemented, but also the procedures required. Such situations may confuse researchers.
    Language English
    Publishing date 2022-06-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2835333-X
    ISSN 2352-3204 ; 2352-3204
    ISSN (online) 2352-3204
    ISSN 2352-3204
    DOI 10.1016/j.reth.2022.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study.

    Iimura, Yohei / Nakazawa, Mitsuko / Tsuru, Yukari / Togashi, Hitomi / Honda, Tomoe / Baba, Keisuke / Ishibashi, Masaaki / Sasuga, Chieko / Furukawa, Naoki / Sato, Tomoko / Matsubara, Yasuo / Kamisato, Ayako / Yoshii, Eiko / Kuroda, Seiichiro / Boku, Narikazu

    BMC gastroenterology

    2023  Volume 23, Issue 1, Page(s) 215

    Abstract: Background: Although the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer support team (MCST) to facilitate ... ...

    Abstract Background: Although the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer support team (MCST) to facilitate cooperation across multidisciplinary medical staff in our hospital and established clinical evidence of supportive care. This study aimed to prospectively evaluate the clinical activity and effect of MCST in patients with gastrointestinal cancer receiving chemotherapy.
    Methods: This is a single-center, single-arm, observational study. Patients with gastrointestinal cancer scheduled to receive chemotherapy are enrolled and supported by the MCST. The primary endpoints are the number of interventions by medical staff and the number of patients who showed improvement in side effects. The secondary endpoints are the severity of side effects, medical expenses, number of consultations, the acceptance rate of prescription recommendations, adjuvant chemotherapy completion rates, dose intensity, and time required for co-medical intervention. In addition, medical staff and attending physicians evaluate all adverse events.
    Discussion: This study is expected to contribute to establishing new cancer-supportive care teams for patients with gastrointestinal cancer receiving chemotherapy and those with cancer receiving chemotherapy.
    Trial registration: This trial was registered in the Japan Registry of Clinical Trials (jRCT) as jRCT1030220495. The date of first registration, 29/11/2022, https://jrct.niph.go.jp/search.
    MeSH term(s) Humans ; Gastrointestinal Neoplasms/drug therapy ; Chemotherapy, Adjuvant ; Japan ; Prospective Studies ; Observational Studies as Topic
    Language English
    Publishing date 2023-06-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041351-8
    ISSN 1471-230X ; 1471-230X
    ISSN (online) 1471-230X
    ISSN 1471-230X
    DOI 10.1186/s12876-023-02849-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Surrogacy: donor conception regulation in Japan.

    Semba, Yukari / Chang, Chiungfang / Hong, Hyunsoo / Kamisato, Ayako / Kokado, Minori / Muto, Kaori

    Bioethics

    2010  Volume 24, Issue 7, Page(s) 348–357

    Abstract: As of 2008, surrogacy is legal and openly practised in various places; Japan, however, has no regulations or laws regarding surrogacy. This paper reports the situation of surrogacy in Japan and in five other regions (the USA, the UK, Taiwan, Korea and ... ...

    Abstract As of 2008, surrogacy is legal and openly practised in various places; Japan, however, has no regulations or laws regarding surrogacy. This paper reports the situation of surrogacy in Japan and in five other regions (the USA, the UK, Taiwan, Korea and France) to clarify the pros and cons of prohibiting surrogacy, along with the problems and issues relating to surrogacy compensation. Not only in a country such as France that completely prohibits surrogacy within the country, but also in a country such as the UK that allows non-commercial surrogacy, infertile couples travel overseas for the purpose of surrogacy. In addition, some couples might seek underground surrogacy if the government prohibits surrogacy. If an intended parent couple and a surrogate make an agreement among themselves and then a problem occurs, they cannot ask for support from professionals or bring a case to court, as can be observed in South Korea and Taiwan. We also conclude that there is little difference between commercial surrogacy and non-commercial surrogacy in the absence of a clear definition of 'reasonable expenses.' In the UK, the law does not allow surrogates to receive compensation. However, in reality, there may be little difference between the amounts paid to surrogates for profit in the US and those paid to surrogates for reasonable expenses in the UK. We conclude that the issue of surrogacy demands further discussion in Japan.
    MeSH term(s) Commerce/legislation & jurisprudence ; Female ; Humans ; Japan ; Medical Tourism ; Pregnancy ; Reproductive Rights/legislation & jurisprudence ; Reproductive Techniques, Assisted/legislation & jurisprudence ; Surrogate Mothers/legislation & jurisprudence
    Language English
    Publishing date 2010-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 632984-6
    ISSN 1467-8519 ; 0269-9702
    ISSN (online) 1467-8519
    ISSN 0269-9702
    DOI 10.1111/j.1467-8519.2009.01780.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2998: Show issues Location:
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