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  1. Article: [Arsenic Poisoning, in Murder is Easy].

    Kanda, Takashi

    Brain and nerve = Shinkei kenkyu no shinpo

    2023  Volume 75, Issue 12, Page(s) 1305–1308

    Abstract: Agatha Christie's detective novel Murder is Easy has the title with the message that the perpetrator of a serial murder in the English countryside was actually an unimaginable individual, and that murder is easy unless it is imagined. In the novel, ... ...

    Abstract Agatha Christie's detective novel Murder is Easy has the title with the message that the perpetrator of a serial murder in the English countryside was actually an unimaginable individual, and that murder is easy unless it is imagined. In the novel, arsenic is used as a murder tool. Therefore, and this essay aims to educate the readers about the neurological symptoms of arsenic poisoning. In the future, criminal acts using arsenic may appear before us. For reliable diagnosis, it is a major premise to have the basic knowledge written here; simultaneously, this novel shows that flexible thinking that is not bound by common sense is also required.
    MeSH term(s) Humans ; Arsenic Poisoning ; Arsenic ; Homicide
    Chemical Substances Arsenic (N712M78A8G)
    Language Japanese
    Publishing date 2023-12-14
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202528
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: [A Beginners' Guide to Scientific Writing and Critical Reading].

    Kanda, Takashi

    Brain and nerve = Shinkei kenkyu no shinpo

    2022  Volume 74, Issue 4, Page(s) 319–328

    Abstract: Writing a scientific paper is a time-consuming task that requires enormous effort, especially for beginners. However, novel scientific discoveries or useful clinical information obtained from a single patient may not be shared with the scientific and ... ...

    Abstract Writing a scientific paper is a time-consuming task that requires enormous effort, especially for beginners. However, novel scientific discoveries or useful clinical information obtained from a single patient may not be shared with the scientific and medical community if they are not published. This short article is intended to inform beginners and their tutors on how to write a scientific paper/case report in the field of neuroscience in Japanese. In addition, the methods used to conduct the peer review process are briefly mentioned. To write a scientific article, authors are required to use simple and direct expressions to avoid unnecessary misunderstandings. The introduction section must be attractive and flow from providing general to specific information, and the final discussion section should pertain to specific matter and end with general statements. A paper will be successful if the readers appreciate this "scientific arch" as a cardinal message of the article. Intensive reading of colleagues' papers also helps develop the beginners' writing skills. Although young researchers/physicians have rare opportunities to review scientific articles, peer-review experiences are useful for writing papers in the future.
    MeSH term(s) Humans ; Publishing
    Language Japanese
    Publishing date 2022-04-18
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  3. Article: [Encephalitis Lethargica: Awakenings].

    Kanda, Takashi

    Brain and nerve = Shinkei kenkyu no shinpo

    2022  Volume 74, Issue 12, Page(s) 1327–1330

    Abstract: Postencephalitic parkinsonism is a characteristic chronic sequelae of encephalitis lethargica, a pandemic disorder which swept the whole world in 1917-1928. Based on his clinical experiences at the Mount Carmel hospital, Oliver Sacks published Awakenings ...

    Abstract Postencephalitic parkinsonism is a characteristic chronic sequelae of encephalitis lethargica, a pandemic disorder which swept the whole world in 1917-1928. Based on his clinical experiences at the Mount Carmel hospital, Oliver Sacks published Awakenings in 1973, and an American drama film Awakenings was premiered in 1990. Success and setbacks of the levodopa trial in postencephalitic parkinsonism patients were chronologically described, and the mother's delight on her son's "return" was impressive; this scene can be shared by us neurologists, even if it was transient. Above all, the exemplary performances of the two distinguished actors, Robin Williams and Robert De Niro (especially the latter), enlivened the most excellent moments of the movie.
    Language Japanese
    Publishing date 2022-12-08
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article: [Shostakovich and Right Hand Weakness].

    Kanda, Takashi

    Brain and nerve = Shinkei kenkyu no shinpo

    2021  Volume 73, Issue 12, Page(s) 1309–1318

    Abstract: Russian composer Dmitri Dmitrievich Shostakovich (25 September 1903-9 August 1975) is sometimes considered to be a famous person who suffered from ALS. However, there are no medical records that mention that his asymmetric weakness was due to ALS, and ... ...

    Abstract Russian composer Dmitri Dmitrievich Shostakovich (25 September 1903-9 August 1975) is sometimes considered to be a famous person who suffered from ALS. However, there are no medical records that mention that his asymmetric weakness was due to ALS, and the exact diagnosis of his illness, which lasted over 17 years, is still obscure. The aim of this paper is to consider what kind of neurological disorder this great composer of the 20th century suffered from based on his piano recordings, photographs, and documents written by his colleagues.
    MeSH term(s) Famous Persons ; Hand ; History, 19th Century ; History, 20th Century ; Humans ; Music ; Nervous System Diseases
    Language Japanese
    Publishing date 2021-11-30
    Publishing country Japan
    Document type Historical Article ; Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416201940
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: [Therapeutic Strategies for Inflammatory Neuropathy].

    Nishihara, Hideaki / Kanda, Takashi

    Brain and nerve = Shinkei kenkyu no shinpo

    2023  Volume 75, Issue 5, Page(s) 533–538

    Abstract: Most cases of inflammatory neuropathy can be treated. It is important to treat patients before axonal degeneration can cause irreversible damage. Conventional treatments include corticosteroids, intravenous immunoglobulin (IVIg), and plasma exchange. ... ...

    Abstract Most cases of inflammatory neuropathy can be treated. It is important to treat patients before axonal degeneration can cause irreversible damage. Conventional treatments include corticosteroids, intravenous immunoglobulin (IVIg), and plasma exchange. Recently, the efficacy of various immunosuppressive and biological agents has increased. Drug efficacy varies depending on the disease and the underlying pathomechanisms. In addition, patients often respond differently to each treatment; therefore, selecting the most appropriate treatment for each patient by assessing the severity of the disease and the efficacy of drugs at appropriate time points is necessary.
    MeSH term(s) Humans ; Immunosuppressive Agents/therapeutic use ; Immunoglobulins, Intravenous/therapeutic use ; Adrenal Cortex Hormones/therapeutic use ; Plasma Exchange ; Immunotherapy ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
    Chemical Substances Immunosuppressive Agents ; Immunoglobulins, Intravenous ; Adrenal Cortex Hormones
    Language Japanese
    Publishing date 2023-03-07
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202373
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article: [Peripheral Neuropathy and Myopathy Associated with COVID-19].

    Honda, Masaya / Kanda, Takashi

    Brain and nerve = Shinkei kenkyu no shinpo

    2022  Volume 74, Issue 7, Page(s) 867–871

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated coronavirus disease (COVID-19) were reported to originate from Wuhan, China, in December 2019, spreading rapidly worldwide. With the emergence of this pandemic, an increasing ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated coronavirus disease (COVID-19) were reported to originate from Wuhan, China, in December 2019, spreading rapidly worldwide. With the emergence of this pandemic, an increasing number of cases of Guillain-Barré syndrome (GBS) have been reported following this infection. Most patients had a demyelinating subtype of GBS. The time interval between infectious and neuropathic symptoms, absence of cerebrospinal fluid pleocytosis, and negative polymerase chain reaction test result support a postinfectious mechanism. Skeletal muscle injury presents as muscle pain and elevated serum creatine kinase level in patients with COVID-19. Some patients developed several myopathic manifestations, including new-onset inflammatory myopathy. Muscle injury is caused by direct SARS-CoV-2 infection or through parainfectious mechanisms such as type I interferonopathy.
    MeSH term(s) COVID-19/complications ; Guillain-Barre Syndrome/diagnosis ; Guillain-Barre Syndrome/etiology ; Humans ; Myalgia/complications ; Pandemics ; SARS-CoV-2
    Language Japanese
    Publishing date 2022-07-20
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Article: [Steroid-Resistant Central Nervous System Sarcoidosis: The Selections of Multi-Agent Combination as the Initial Treatment].

    Fujisawa, Miwako / Kanda, Takashi

    Brain and nerve = Shinkei kenkyu no shinpo

    2022  Volume 74, Issue 5, Page(s) 455–461

    Abstract: Sarcoidosis is a granulomatous multiorgan disease of unknown etiology that commonly affects the respiratory system, eyes, and skin, and less commonly affects the nervous system. Because of its rarity, a standard treatment for central nervous system (CNS) ...

    Abstract Sarcoidosis is a granulomatous multiorgan disease of unknown etiology that commonly affects the respiratory system, eyes, and skin, and less commonly affects the nervous system. Because of its rarity, a standard treatment for central nervous system (CNS) sarcoidosis has not yet been established. Corticosteroids remain the cornerstone of CNS sarcoidosis treatment. However, CNS sarcoidosis, other than isolated facial nerve paralysis, is often refractory to treatment and requires long-term corticosteroid treatment. In particular, patients with hydrocephalus have a high mortality rate and a lack of response to this treatment. Therefore, immunosuppressants, including TNF-α inhibitors and corticosteroids, should be considered as the initial treatment. For older patients, it is important to pay attention to infection as an adverse event and to the toxicity of the therapeutic agents. Because steroid-related adverse events are more common in the older patient group, the lowest effective dose should be used, and the treatment duration should be kept as short as possible after careful evaluation of disease activity. Corticosteroid-sparing agents are effective at reducing the cumulative toxicity of corticosteroids. Recently, various new potential agents have emerged and their efficacy has been assessed. It is expected that more treatment options will be available for CNS sarcoidosis in future.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Central Nervous System ; Central Nervous System Diseases ; Humans ; Sarcoidosis/drug therapy ; Steroids/therapeutic use
    Chemical Substances Adrenal Cortex Hormones ; Steroids
    Language Japanese
    Publishing date 2022-05-16
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article: [Varicella-Zoster Virus Infection in the Central Nervous System].

    Nemoto, Joe / Kanda, Takashi

    Brain and nerve = Shinkei kenkyu no shinpo

    2022  Volume 74, Issue 10, Page(s) 1171–1178

    Abstract: Varicella-zoster virus (VZV) is known to causes various inflammatory disorders of the central nervous system (CNS) such as encephalitis, meningitis, and myelitis. Similar to the varicella rashes, these conditions are associated with the reactivation of ... ...

    Abstract Varicella-zoster virus (VZV) is known to causes various inflammatory disorders of the central nervous system (CNS) such as encephalitis, meningitis, and myelitis. Similar to the varicella rashes, these conditions are associated with the reactivation of VZV. Ganglionitis and vasculitis, in particular, may be linked to the pathogenesis of VZV infection in the CNS. This review provides an overview of the clinical presentation, diagnosis, treatment, and prognosis of VZV infection in the CNS based on its distinct pathophysiology.
    MeSH term(s) Central Nervous System ; Chickenpox ; Herpes Zoster/pathology ; Herpesvirus 3, Human ; Humans ; Myelitis
    Language Japanese
    Publishing date 2022-08-31
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effects of biochar application depth on nitrate leaching and soil water conditions.

    Hamada, Kosuke / Nakamura, Satoshi / Kanda, Takashi / Takahashi, Minako

    Environmental technology

    2023  , Page(s) 1–12

    Abstract: Nitrate leaching from farmland pollutes the surrounding environment, such as groundwater, causing health hazards to inhabitants. To mitigate the leaching, biochar can be applied. The effect of biochar application differs depending on the application ... ...

    Abstract Nitrate leaching from farmland pollutes the surrounding environment, such as groundwater, causing health hazards to inhabitants. To mitigate the leaching, biochar can be applied. The effect of biochar application differs depending on the application depth; however, the effect of the application depth remains unclear. To evaluate the effect, we conducted a pipe experiment with no plant using bagasse biochar with four treatments: no biochar application, surface application (0-5 cm), plow layer application (0-30 cm), and subsurface application (25-30 cm). The results showed that surface and plow layer applications reduced nitrate leaching, whereas subsurface application did not affect leaching. This difference was due to changes in the soil water movement and water budget. Surface application reduced evaporation, inducing increases in both drainage and the amount of water in the pipe. The increased amount of water might contribute to an increase in the amount of nitrogen in the pipe, reducing the leaching. Plow layer application increased evaporation, leading to decreased drainage and nitrate leaching. Subsurface application did not affect drainage and nitrate leaching; however, the change in the volumetric water content at a depth of 10 cm was the most significant among the treatments. Our study indicated that, although the same amount of biochar was applied, the effect of biochar application differs depending on the application depth.
    Language English
    Publishing date 2023-11-16
    Publishing country England
    Document type Journal Article
    ISSN 1479-487X
    ISSN (online) 1479-487X
    DOI 10.1080/09593330.2023.2283403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Mesial temporal lobe epilepsy with hippocampal sclerosis as a neuroimmunological disorder.

    Kanda, Takashi

    Journal of neurology, neurosurgery, and psychiatry

    2016  Volume 87, Issue 7, Page(s) 683

    Language English
    Publishing date 2016-07
    Publishing country England
    Document type Editorial
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp-2016-313358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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