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Article: Spontaneous Coronary Artery Disease (SCAD) in a Patient With Systemic Lupus Erythematosus (SLE).

Patel, Ravi / Patel, Richa / Rahming, Hamfreth / Tian, Julia / Kandov, Ruben

2023 Volume 15, Issue 8, Page(s) e43061

Abstract: Spontaneous coronary artery dissection (SCAD) is a rare phenomenon that emerges as an acute coronary syndrome (ACS) and sudden cardiac death, especially in young women. We report a case of a woman with systemic lupus erythematosus (SLE) who presented ... ...

Abstract	Spontaneous coronary artery dissection (SCAD) is a rare phenomenon that emerges as an acute coronary syndrome (ACS) and sudden cardiac death, especially in young women. We report a case of a woman with systemic lupus erythematosus (SLE) who presented with syncope and was found to have SCAD.
Language	English
Publishing date	2023-08-07
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.43061
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Curious Case of an Anomalous Right Coronary Artery.

Cinelli, Michael / Rahming, Hamfreth / Assaad, Marc / Singh, Chetan / Aridi, Hussam / Karam, Boutros / Kandov, Ruben

Cardiology research

2022 Volume 13, Issue 4, Page(s) 246–249

Abstract: Single coronary artery (SCA) is an unusual congenital anomaly, seen by diagnostic coronary angiography. Absence of the right coronary artery (RCA) is one of the rarest coronary artery anomalies occurring when the artery fails to develop in the right ... ...

Abstract	Single coronary artery (SCA) is an unusual congenital anomaly, seen by diagnostic coronary angiography. Absence of the right coronary artery (RCA) is one of the rarest coronary artery anomalies occurring when the artery fails to develop in the right atrioventricular (AV) groove. Herein, we describe the case of a 58-year-old man presenting with new onset decompensated congestive heart failure found to have a congenitally absent right coronary ostium. The AV groove extended such that the left circumflex artery supplied the domain of the RCA. Such coronary artery anomalies are rare, and we aim to shed further insight into these congenital processes so that operators may remain vigilant of them in their practice.
Language	English
Publishing date	2022-08-15
Publishing country	Canada
Document type	Case Reports
ZDB-ID	2598593-0
ISSN	1923-2837 ; 1923-2829
ISSN (online)	1923-2837
ISSN	1923-2829
DOI	10.14740/cr1406
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Article: Coronary Artery Diffuse Aneurysmal Dilation in an Acute Myocardial Infarction Patient.

Elhosseiny, Sherif / Barsoum, Emad / Kandov, Ruben / Lafferty, James C / Zgheib, Mohammad

Cureus

2019 Volume 11, Issue 5, Page(s) e4747

Abstract: Coronary artery aneurysm (CAA) is a rare disease that is associated with dangerous dormant complications. It is associated with atherosclerotic heart disease in half of the cases during a coronary angiogram. Currently, there are no guidelines for the ... ...

Abstract	Coronary artery aneurysm (CAA) is a rare disease that is associated with dangerous dormant complications. It is associated with atherosclerotic heart disease in half of the cases during a coronary angiogram. Currently, there are no guidelines for the management of such cases. We present a case of acute ST-segment elevation myocardial infarction in a male patient who was found to have diffuse aneurysmal dilation of the coronary arteries along with 100% occlusion of the right coronary artery. The complexity of the lesions caused him not to be a candidate for either percutaneous or surgical intervention. This raises an important question regarding treatment options in such a rare case.
Language	English
Publishing date	2019-05-24
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.4747
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Article: Calreticulin Mutated Essential Thrombocythemia Presenting as Acute Coronary Syndrome.

Nazha, Bassel / Garcia, Gwenalyn / Kandov, Ruben / Odaimi, Marcel

Case reports in hematology

2015 Volume 2015, Page(s) 161764

Abstract: Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by a clonal expansion of megakaryocytes. ET can result in both arterial and venous thrombosis. Involvement of the coronary arteries has been reported. Patients who harbor a ... ...

Abstract	Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by a clonal expansion of megakaryocytes. ET can result in both arterial and venous thrombosis. Involvement of the coronary arteries has been reported. Patients who harbor a CALR mutation are half as likely to suffer a thrombotic event as compared to patients with a JAK2 mutation. We report a case of CALR-mutated ET whose initial disease manifestation was a non-ST segment elevation myocardial infarction.
Language	English
Publishing date	2015-04-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	2627639-2
ISSN	2090-6579 ; 2090-6560
ISSN (online)	2090-6579
ISSN	2090-6560
DOI	10.1155/2015/161764
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Article ; Online: Gender-related Disparities of Percutaneous Coronary Interventions in ST-elevation Myocardial Infarction: A Retrospective Chart Review of 500 Patients.

Sleiman, Elsa / Hosry, Jeff / Caruana, Lisa / Schwartz, Moishe / Boutros, Karam / Tabet, Rabih / Salmane, Chadi / Kandov, Ruben / Royzman, Roman / Tamburrino, Frank / Lafferty, James

Critical pathways in cardiology

2020 Volume 20, Issue 2, Page(s) 63–66

Abstract: Door-to-balloon (DTB) time of primary percutaneous coronary intervention in ST-elevation myocardial infarction (STEMI) is a predictive indicator of outcomes and mortality. Traditional gender-related differences that existed in the provision of DTB in ... ...

Abstract	Door-to-balloon (DTB) time of primary percutaneous coronary intervention in ST-elevation myocardial infarction (STEMI) is a predictive indicator of outcomes and mortality. Traditional gender-related differences that existed in the provision of DTB in STEMI had been allegedly improving until recent controversial data showed re-emergence of longer DTB in females. The objective of our study was to compare circadian disparities in percutaneous coronary intervention for STEMI according to gender in our institution. We compared DTB and symptom-to-balloon (STB) as well as mortality outcomes in a registry of 514 patients. We studied 117 females and 397 males. Baseline characteristics and cardiovascular risk factors were similar among both populations. Men used more self-transportation (51% vs. 38%) compared with women. Both had similar DTB median times: males, 63 (47-79) min; and females, 61 (44-76) min. In addition, STB median times were also similar: males, 155 (116-264) min; and females, 165 (115-261) min. Mortality outcomes at 1 month were comparable at 3% in males versus 0.9% in females (P = 0.164). In a review of a tertiary care center in New York, we observed no gender differences in DTB and STB, endorsing the role of emergency medical service transportation in eliminating disparities.
MeSH term(s)	Female ; Humans ; Male ; Percutaneous Coronary Intervention ; Registries ; Retrospective Studies ; ST Elevation Myocardial Infarction/surgery ; Time Factors ; Treatment Outcome
Language	English
Publishing date	2020-08-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2079676-6
ISSN	1535-2811 ; 1535-282X
ISSN (online)	1535-2811
ISSN	1535-282X
DOI	10.1097/HPC.0000000000000238
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Article ; Online: Short- and Mid-Term Outcomes of Complex and High-Risk Versus Standard Percutaneous Coronary Interventions in Patients Undergoing Transcatheter Aortic Valve Replacement.

The Journal of invasive cardiology

2022 Volume 35, Issue 2, Page(s) E92–E98

Abstract: Background: The prevalence of coronary artery disease (CAD) in patients undergoing TAVR varies and is associated with increased morbidity and mortality. We evaluated the outcomes of complex and high-risk percutaneous coronary interventions (CHIP-PCIs) ... ...

Abstract	Background: The prevalence of coronary artery disease (CAD) in patients undergoing TAVR varies and is associated with increased morbidity and mortality. We evaluated the outcomes of complex and high-risk percutaneous coronary interventions (CHIP-PCIs) and TAVR compared with standard PCI and TAVR. Between January 2014 and March 2021, a total of 276 consecutive patients with severe aortic stenosis (AS) who underwent TAVR and PCI at 3 centers within Northwell Health were retrospectively reviewed. CHIP-PCI was defined as PCI with one of the following: left ventricular ejection fraction (LVEF) <30%; left main coronary artery (LMCA)/chronic total occlusion (CTO) intervention; atherectomy; or need for left ventricular (LV) support. One hundred twenty- seven patients (46%) had CHIP-PCI prior to TAVR and 149 patients (54%) had standard PCI. Thirteen percent of CHIP-PCI and 22% of standard PCI cases were done concomitantly with TAVR. CHIP-PCI criteria were met for low EF (19%), LMCA (25%), CTO (3%), LV support (20%), and atherectomy (50%). The types of valves used were similarly divided (49% balloon expandable vs 51% self expanding. Major adverse cardiac or cerebrovascular event (MACCE) rate for CHIP-PCI/TAVR was 4.9% at 30 days vs 1.3% for standard PCI/TAVR (P=.09), driven by in-hospital stroke. At 1 year, the rates of MACCE for CHIP-PCI/TAVR remained higher than for standard PCI/TAVR, but was not statistically significant (8.7% vs 4%; P=.06), driven by revascularization. We found no differences between major and/or minor vascular complications. New York Heart Association classification at 1 month was similar (I/II 93% vs 95%; P=.87). Our study suggests that CHIP-PCI can be safely performed in patients with complex CAD and concomitant severe AS.
MeSH term(s)	Humans ; Transcatheter Aortic Valve Replacement/adverse effects ; Percutaneous Coronary Intervention/adverse effects ; Aortic Valve Stenosis/complications ; Aortic Valve Stenosis/diagnosis ; Aortic Valve Stenosis/surgery ; Retrospective Studies ; Stroke Volume ; Treatment Outcome ; Ventricular Function, Left ; Coronary Artery Disease/complications ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/surgery ; Aortic Valve/surgery ; Risk Factors
Language	English
Publishing date	2022-12-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	1154372-3
ISSN	1557-2501 ; 1042-3931
ISSN (online)	1557-2501
ISSN	1042-3931
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Zs.A 3701: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Biodegradable polymer stents vs second generation drug eluting stents: A meta-analysis and systematic review of randomized controlled trials.

Pandya, Bhavi / Gaddam, Sainath / Raza, Muhammad / Asti, Deepak / Nalluri, Nikhil / Vazzana, Thomas / Kandov, Ruben / Lafferty, James

World journal of cardiology

2016 Volume 8, Issue 2, Page(s) 240–246

Abstract: Aim: To evaluate the premise, that biodegradable polymer drug eluting stents (BD-DES) could improve clinical outcomes compared to second generation permanent polymer drug eluting stents (PP-DES), we pooled the data from all the available randomized ... ...

Abstract	Aim: To evaluate the premise, that biodegradable polymer drug eluting stents (BD-DES) could improve clinical outcomes compared to second generation permanent polymer drug eluting stents (PP-DES), we pooled the data from all the available randomized control trials (RCT) comparing the clinical performance of both these stents. Methods: A systematic literature search of PubMed, Cochrane, Google scholar databases, EMBASE, MEDLINE and SCOPUS was performed during time period of January 2001 to April 2015 for RCT and comparing safety and efficacy of BD-DES vs second generation PP-DES. The primary outcomes of interest were definite stent thrombosis, target lesion revascularization, myocardial infarction, cardiac deaths and total deaths during the study period. Results: A total of 11 RCT's with a total of 12644 patients were included in the meta-analysis, with 6598 patients in BD-DES vs 6046 patients in second generation PP-DES. The mean follow up period was 16 mo. Pooled analysis showed non-inferiority of BD-DES, comparing events of stent thrombosis (OR = 1.42, 95%CI: 0.79-2.52, P = 0.24), target lesion revascularization (OR = 0.99, 95%CI: 0.84-1.17, P = 0.92), myocardial infarction (OR = 1.06, 95%CI: 0.86-1.29, P = 0.92), cardiac deaths (OR = 1.07, 95%CI 0.82-1.41, P = 0.94) and total deaths (OR = 0.96, 95%CI: 0.80-1.17, P = 0.71). Conclusion: BD-DES, when compared to second generation PP-DES, showed no significant advantage and the outcomes were comparable between both the groups.
Language	English
Publishing date	2016-03-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573665-6
ISSN	1949-8462
ISSN	1949-8462
DOI	10.4330/wjc.v8.i2.240
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Article ; Online: Propensity matched comparison of in-hospital outcomes of TAVR vs. SAVR in patients with previous history of CABG: Insights from the Nationwide inpatient sample.

Nalluri, Nikhil / Atti, Varunsiri / Patel, Nileshkumar J / Kumar, Varun / Arora, Shilpkumar / Nalluri, Sreeram / Nelluri, Bhargava Krishna / Maniatis, Gregory A / Kandov, Ruben / Kliger, Chad

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

2018 Volume 92, Issue 7, Page(s) 1417–1426

Abstract: Background: The incidence of patients with previous history of coronary artery bypass grafting (CABG) presenting for aortic valvular replacement has been consistently on the rise. Repeat sternotomy for surgical aortic valve replacement (SAVR) carries an ...

Abstract	Background: The incidence of patients with previous history of coronary artery bypass grafting (CABG) presenting for aortic valvular replacement has been consistently on the rise. Repeat sternotomy for surgical aortic valve replacement (SAVR) carries an inherent risk of morbidity and mortality when compared to Transcatheter aortic valve replacement (TAVR). Methods: The Nationwide inpatient sample (NIS) from 2012 to 2014 was queried using the International Classification of Diseases-Ninth edition, Clinical Modification (ICD-9-CM) codes to identify all patients ≥ 18 years with prior CABG who underwent TAVR (35.05 and 35.06) or SAVR (35.21 and 35.22). Propensity score matching (1:1) was performed and in-hospital outcomes were compared between matched cohorts. Results: From 2012 to 2014, there was progressive increase in the annual number of TAVR procedures from 1485 to 4020, with a decrease in patients undergoing SAVR from 2330 to 1955 (P Conclusion: In this large cohort of patients with previous CABG, there is no significant difference in in-hospital mortality between TAVR and SAVR. TAVR was associated with lower risk of in-hospital outcomes.
MeSH term(s)	Aged ; Aged, 80 and over ; Coronary Artery Bypass/adverse effects ; Coronary Artery Bypass/mortality ; Coronary Artery Disease/mortality ; Coronary Artery Disease/surgery ; Databases, Factual ; Female ; Heart Valve Diseases/mortality ; Heart Valve Diseases/surgery ; Heart Valve Prosthesis Implantation/adverse effects ; Heart Valve Prosthesis Implantation/mortality ; Heart Valve Prosthesis Implantation/trends ; Hospital Mortality ; Humans ; Inpatients ; Male ; Postoperative Complications/mortality ; Postoperative Complications/therapy ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Sternotomy/adverse effects ; Sternotomy/mortality ; Sternotomy/trends ; Time Factors ; Transcatheter Aortic Valve Replacement/adverse effects ; Transcatheter Aortic Valve Replacement/mortality ; Transcatheter Aortic Valve Replacement/trends ; Treatment Outcome ; United States/epidemiology
Language	English
Publishing date	2018-08-05
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Observational Study
ZDB-ID	1459995-8
ISSN	1522-726X ; 1522-1946
ISSN (online)	1522-726X
ISSN	1522-1946
DOI	10.1002/ccd.27708
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Zs.A 1226: Show issues

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Article ; Online: Contrast media use in patients with chronic kidney disease undergoing coronary angiography: A systematic review and meta-analysis of randomized trials.

Pandya, Bhavi / Chaloub, Jean / Parikh, Valay / Gaddam, Sainath / Spagnola, Jonathan / El-Sayegh, Suzanne / Bogin, Marc / Kandov, Ruben / Lafferty, James / Bangalore, Sripal

International journal of cardiology

2017 Volume 228, Page(s) 137–144

Abstract: Background: Patients with chronic kidney disease (CKD) undergoing coronary angiography (CA), adequate hydration and minimizing volume of contrast media (CM) are class 1b recommendations for preventing contrast induced nephropathy (CIN). Current data are ...

Abstract	Background: Patients with chronic kidney disease (CKD) undergoing coronary angiography (CA), adequate hydration and minimizing volume of contrast media (CM) are class 1b recommendations for preventing contrast induced nephropathy (CIN). Current data are insufficient to justify specific recommendations about isoosmolar vs. low-osmolar contrast media by the ACCF/AHA/SCAI guidelines. Methods: Randomized trials comparing IOCM to LOCM in CKD stage 3 and above patients undergoing CA, and reporting incidence of CIN (defined by a rise in creatinine of 25% from baseline) were included in the analysis. The secondary outcome of the study was the incidence of serum creatinine increase by >1mg/dl. Results: A total of 2839 patients were included in 10 trials, in which 1430 patients received IOCM and 1393 received LOCM. When compared to LOCM, IOCM was not associated with significant benefit in preventing CIN (OR=0.72, [CI: 0.50-1.04], P=0.08, I2=59%). Subgroup analysis revealed non-significant difference in incidence of CIN based on baseline use of N-acetylcystine (NAC), diabetes status, ejection fraction, and whether percutaneous coronary intervention vs coronary angiography alone was performed. The difference between IOCM and LOCM was further attenuated when restricted to studies with larger sample size (>250 patients) (OR=0.93; [CI: 0.66-1.30]) or when compared with non-ionic LOCM (OR=0.79, [CI: 0.52-1.21]). Conclusion: In patients with CKD stage 3 and above undergoing coronary angiography, use of IOCM showed overall non-significant difference in incidence of CIN compared to LOCM. The difference was further attenuated when IOCM was compared with non-ionic LOCM.
MeSH term(s)	Contrast Media/classification ; Contrast Media/pharmacology ; Coronary Angiography/adverse effects ; Coronary Angiography/methods ; Coronary Disease/complications ; Coronary Disease/diagnosis ; Humans ; Kidney Diseases/chemically induced ; Kidney Diseases/prevention & control ; Kidney Function Tests ; Preventive Medicine/methods ; Renal Insufficiency, Chronic/complications
Chemical Substances	Contrast Media
Language	English
Publishing date	2017-02-01
Publishing country	Netherlands
Document type	Journal Article ; Meta-Analysis
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2016.11.170
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Article ; Online: Corrigendum to "Contrast media use in patients with chronic kidney disease undergoing coronary angiography: A systematic review and meta-analysis of randomized trials" [Int. J. Cardiol. (2017) 137-144].

Pandya, Bhavi / Chalhoub, Jean M / Parikh, Valay / Gaddam, Sainath / Spagnola, Jonathan / El-Sayegh, Suzanne / Bogin, Marc / Kandov, Ruben / Lafferty, James / Bangalore, Sripal

International journal of cardiology

2017 Volume 235, Page(s) 205

Language	English
Publishing date	2017-05-15
Publishing country	Netherlands
Document type	Published Erratum
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2017.03.021
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