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Article ; Online: 자기공명영상 유도하 유방의 중재적시술: 조직생검술 및 침위치결정술.

Park, Ga Eun / Lee, Jeongmin / Kang, Bong Joo / Kim, Sung Hun

Journal of the Korean Society of Radiology

2023 Volume 84, Issue 2, Page(s) 345–360

Abstract: In Korea, the number of institutions providing breast MRI, as well as the number of breast MRIs, has recently increased. However, MRI-guided procedures, including biopsy and needle localization, are rarely performed compared to ultrasound-guided or ... ...

Title translation	MRI-Guided Breast Intervention: Biopsy and Needle Localization.
Abstract	In Korea, the number of institutions providing breast MRI, as well as the number of breast MRIs, has recently increased. However, MRI-guided procedures, including biopsy and needle localization, are rarely performed compared to ultrasound-guided or stereotactic biopsy. As breast MRI has high sensitivity but limited specificity, lesions detected only on MRI require pathologic confirmation through MRI-guided biopsy or surgical excision with MRI-guided needle localization. Thus, we aimed to review MRI-guided procedures, including their indications, techniques, procedural considerations, and limitations.
Language	Korean
Publishing date	2023-03-28
Publishing country	Korea (South)
Document type	English Abstract ; Journal Article ; Review
ISSN	2951-0805
ISSN (online)	2951-0805
DOI	10.3348/jksr.2022.0162
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The Role of Diffusion-Weighted Imaging Based on Maximum-Intensity Projection in Young Patients with Marked Background Parenchymal Enhancement on Contrast-Enhanced Breast MRI.

Park, Ga-Eun / Kang, Bong-Joo / Kim, Sung-Hun / Jung, Na-Young

Life (Basel, Switzerland)

2023 Volume 13, Issue 8

Abstract: Diffusion-weighted imaging (DWI) utilizing maximum-intensity projection (MIP) was suggested as a cost-effective alternative tool without the risk of gadolinium-based contrast agents. The purpose of this study was to investigate whether DWI MIPs played a ... ...

Abstract	Diffusion-weighted imaging (DWI) utilizing maximum-intensity projection (MIP) was suggested as a cost-effective alternative tool without the risk of gadolinium-based contrast agents. The purpose of this study was to investigate whether DWI MIPs played a supportive role in young (≤60) patients with marked background parenchymal enhancement (BPE) on contrast-enhanced MRI (CE-MRI). The research included 1303 patients with varying degrees of BPE, and correlations between BPE on CE-MRI, the background diffusion signal (BDS) on DWI, and clinical parameters were analyzed. Lesion detection scores were compared between CE-MRI and DWI, with DWI showing higher scores. Among the 186 lesions in 181 patients with marked BPE on CE-MRI, the main lesion on MIPs of CE-MRI was partially or completely seen in 88.7% of cases, while it was not seen in 11.3% of cases. On the other hand, the main lesion on MIPs of DWI was seen in 91.4% of cases, with only 8.6% of cases showing no visibility. DWI achieved higher scores for lesion detection compared to CE-MRI. The presence of a marked BDS was significantly associated with a lower likelihood of a higher DWI score (
Language	English
Publishing date	2023-08-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life13081744
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Article ; Online: Wideband dispersion-free THz waveguide platform.

Rohrbach, David / Kang, Bong Joo / Zyaee, Elnaz / Feurer, Thomas

Scientific reports

2023 Volume 13, Issue 1, Page(s) 15228

Abstract: We present a versatile THz waveguide platform for frequencies between 0.1 THz and 1.5 THz, designed to exhibit vacuum-like dispersion and electric as well as magnetic field enhancement. While linear THz spectroscopy benefits from the extended interaction ...

Abstract	We present a versatile THz waveguide platform for frequencies between 0.1 THz and 1.5 THz, designed to exhibit vacuum-like dispersion and electric as well as magnetic field enhancement. While linear THz spectroscopy benefits from the extended interaction length in combination with moderate losses, nonlinear THz spectroscopy profits from the field enhancement and zero dispersion, with the associated reshaping-free propagation of broadband single- to few-cycle THz pulses. Moreover, the vacuum-like dispersion allows for velocity matching in mixed THz and visible to infrared pump-probe experiments. The platform is based on the motif of a metallic double ridged waveguide. We experimentally characterize essential waveguide properties, for instance, propagation and bending losses, but also demonstrate a junction and an interferometer, essentially because those elements are prerequisites for THz waveform synthesis, and hence, for coherently controlled linear and nonlinear THz interactions.
Language	English
Publishing date	2023-09-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-41843-6
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Article: Combination of shear-wave elastography with ultrasonography for detection of breast cancer and reduction of unnecessary biopsies: a systematic review and meta-analysis.

Park, Sun-Young / Kang, Bong Joo

Ultrasonography (Seoul, Korea)

2020 Volume 40, Issue 3, Page(s) 318–332

Abstract: Purpose: This study was undertaken to compare the diagnostic performance and biopsy reduction rate of combined shear-wave elastography (SWE) and B-mode ultrasonography (US) versus B-mode US alone for breast lesions and to determine the most ... ...

Abstract	Purpose: This study was undertaken to compare the diagnostic performance and biopsy reduction rate of combined shear-wave elastography (SWE) and B-mode ultrasonography (US) versus B-mode US alone for breast lesions and to determine the most discriminatory parameter in SWE. Methods: A systematic review and meta-analysis were conducted. The resources for the study were obtained from MEDLINE, Embase, Cochrane Library, and KoreaMed on August 17, 2018. The quality of the articles was evaluated using the Scottish Intercollegiate Guidelines Network (SIGN) tool. Results: Twenty-five articles with 5,147 breast lesions were selected. The meta-analysis showed pooled sensitivities of 0.94 and 0.97 (P=0.087), pooled specificities of 0.85 and 0.61 (P=0.009), and area under the receiver operating characteristic curve (AUC) of 0.96 and 0.96 (P=0.095) for combined SWE and B-mode US versus B-mode US alone. When SWE was combined with B-mode US, the Breast Imaging Reporting and Data System category changed from 4 to 3 in 71.3% of the tests, decreasing the frequency of unnecessary biopsies by 41.1%. All four parameters of SWE (the color grade of lesion stiffness, maximum elasticity, mean elasticity, and color grade of lesion stiffness/homogeneity of the lesion) improved the specificity when they were added to B-mode US. The AUC for each SWE parameter was 0.99, 0.96, 0.96, and 0.93, respectively. Conclusion: Adding SWE to B-mode US not only provides additional diagnostic information for differentiating between benign and malignant breast lesions, but also decreases the likelihood of unnecessary biopsies.
Language	English
Publishing date	2020-12-24
Publishing country	Korea (South)
Document type	Meta-Analysis
ZDB-ID	2775801-1
ISSN	2288-5943 ; 2288-5919
ISSN (online)	2288-5943
ISSN	2288-5919
DOI	10.14366/usg.20058
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Article ; Online: Usefulness of postoperative surveillance MR for women after breast-conservation therapy: Focusing on MR features of early and late recurrent breast cancer.

Lee, Jeongmin / Kang, Bong Joo / Kim, Sung Hun

PloS one

2021 Volume 16, Issue 6, Page(s) e0252476

Abstract: Purpose: To investigate the imaging characteristics of early and late recurrent breast cancer and the detectability of mammography, ultrasonography, and breast magnetic resonance imaging (MRI) in patients who underwent breast-conservation therapy (BCT).! ...

Abstract	Purpose: To investigate the imaging characteristics of early and late recurrent breast cancer and the detectability of mammography, ultrasonography, and breast magnetic resonance imaging (MRI) in patients who underwent breast-conservation therapy (BCT). Materials and methods: Total of 1312 women with 2026 surveillance breast MRI after BCT between January 2014 and September 2018 were studied. Early recurrence was defined as newly diagnosed breast cancer and/or axillary metastasis within 12 months of surgery. Late recurrence was defined as recurrence after 12months of surgery. We assessed the detectability of recurrent lesions in each postoperative imaging modality and evaluated characteristics of recurrent lesions on postoperative MRI by comparing early and late recurrence groups. Result: Of the 2026 cases, 103 were confirmed as recurrent breast cancer by biopsy or surgery. Thirty-one cases were early recurrence, and 72 cases were late recurrence. MRI showed significantly higher detectability for recurrent lesions (102 cases, 99%) than mammography (59.4%, p < 0.001) or ultrasound (68.9%, p < 0.001), or both mammography and ultrasound (81.6%, p < 0.001). The recurrent lesions did not have typical malignant morphologic features, but variable features on MRI. However, early recurrent lesions showed fast enhancement in early dynamic phase regardless of the kinetic pattern of delayed dynamic phase; and late recurrence lesions showed early fast enhancement and delayed washout pattern. There were 19 cases which were not detected on mammography or ultrasound but could only be detected with MRI. Conclusion: Postoperative breast MRI showed significantly higher detectability for recurrent lesions than mammography and ultrasound. Early fast enhancement is the most important feature of recurrent lesions on postoperative breast MRI for both early and late recurrence groups. Due to its high possibility of recurrence, further work-up should be considered regardless of their morphologic features.
MeSH term(s)	Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/surgery ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Mastectomy, Segmental/methods ; Ultrasonography, Mammary
Language	English
Publishing date	2021-06-11
Publishing country	United States
Document type	Journal Article
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0252476
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Article: The Usefulness of Magnetic Resonance Imaging (MRI) for the Detection of Local Recurrence after Mastectomy with Reconstructive Surgery in Breast Cancer Patients.

Lee, Jeongmin / Kang, Bong Joo / Park, Ga Eun / Kim, Sung Hun

Diagnostics (Basel, Switzerland)

2022 Volume 12, Issue 9

Abstract: The purpose of this study is to investigate the usefulness of magnetic resonance imaging (MRI) for the detection of local recurrence after nipple-sparing mastectomy (NSM) or skin-sparing mastectomy (SSM) with immediate reconstructive surgery for breast ... ...

Abstract	The purpose of this study is to investigate the usefulness of magnetic resonance imaging (MRI) for the detection of local recurrence after nipple-sparing mastectomy (NSM) or skin-sparing mastectomy (SSM) with immediate reconstructive surgery for breast cancer. Two hundred and eighty-six NSM or SSM procedures and immediate reconstruction cases between August 2015 and February 2020 were reviewed. The detectability rates of for local recurrence using MRI and ultrasound were assessed, and the characteristics of recurrent and primary cancers were evaluated. The patients with multifocal or multicentric primary cancer and a dense parenchymal pattern showed a higher recurrence rate (p < 0.001). A total of 22 cases showed recurrence, and due to multifocal recurrence, a total of 27 recurrent lesions were identified in the reconstructed breast, of which 12 were symptomatic and 15 were asymptomatic (p < 0.001). With the exception of skin recurrence (n = 6), MRI showed a significantly higher detectability rate (95.2%, 20 of 21) than ultrasound (38.1%, 8 of 21) for the recurrence of cancer in the reconstructed breast (p < 0.001), especially for small-sized (<1 cm) asymptomatic lesions. In addition, the mean recurrence interval of MRI-detected asymptomatic lesions was 21.7 months (SD ± 17.7), which was significantly longer than that of symptomatic recurrence. In conclusion, postoperative MRI can be useful for identifying small-sized (<1 cm) asymptomatic recurrence lesions in reconstructed breast tissue after NSM or SSM, which can be implemented within two years of surgery.
Language	English
Publishing date	2022-09-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics12092203
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Article: Retrospective Review of Missed Cancer Detection and Its Mammography Findings with Artificial-Intelligence-Based, Computer-Aided Diagnosis.

Park, Ga Eun / Kang, Bong Joo / Kim, Sung Hun / Lee, Jeongmin

Diagnostics (Basel, Switzerland)

2022 Volume 12, Issue 2

Abstract: To investigate whether artificial-intelligence-based, computer-aided diagnosis (AI-CAD) could facilitate the detection of missed cancer on digital mammography, a total of 204 women diagnosed with breast cancer with diagnostic (present) and prior ... ...

Abstract	To investigate whether artificial-intelligence-based, computer-aided diagnosis (AI-CAD) could facilitate the detection of missed cancer on digital mammography, a total of 204 women diagnosed with breast cancer with diagnostic (present) and prior mammograms between 2018 and 2020 were included in this study. Two breast radiologists reviewed the mammographic features and classified them into true negative, minimal sign or missed cancer. They analyzed the AI-CAD results with an abnormality score and assessed whether the AI-CAD correctly localized the known cancer sites. Of the 204 cases, 137 were classified as true negative, 33 as minimal signs, and 34 as missed cancer. The sensitivity, specificity and diagnostic accuracy of AI-CAD were 84.7%, 91.5% and 86.3% on diagnostic mammogram and 67.2%, 91.2% and 83.38% on prior mammogram, respectively. The AI-CAD correctly localized 27 cases from 34 missed cancers on prior mammograms. The findings in the preceding mammography of AI-CAD-detected missed cancer were common in the order of calcifications, focal asymmetry and asymmetry. Asymmetry was the most common finding among the seven cases, which could not be detected by AI-CAD in the missed cases (5/7). The assistance of AI-CAD can be helpful in the early detection of breast cancer in mammography screenings.
Language	English
Publishing date	2022-02-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics12020387
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Article ; Online: 3D-printed THz wave- and phaseplates.

Rohrbach, David / Kang, Bong Joo / Feurer, Thomas

Optics express

2021 Volume 29, Issue 17, Page(s) 27160–27170

Abstract: Three-dimensional printing based on fused deposition modeling has been shown to provide a cost-efficient and time-saving tool for fabricating a variety of THz optics for a frequency range of <0.2 THz. By using a broadband THz source, with a useful ... ...

Abstract	Three-dimensional printing based on fused deposition modeling has been shown to provide a cost-efficient and time-saving tool for fabricating a variety of THz optics for a frequency range of <0.2 THz. By using a broadband THz source, with a useful spectral range from 0.08 THz to 1.5 THz, we show that 3D-printed waveplates operate well up to 0.6 THz and have bandwidths similar to commercial products. Specifically, we investigate quarter- and half-waveplates, q-plates, and spiral phaseplates. We demonstrate a route to achieve broadband performance, so that 3D-printed waveplates can also be used with broadband, few-cycle THz pulses, for instance, in nonlinear THz spectroscopy or other THz high field applications.
Language	English
Publishing date	2021-09-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.433881
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Article: Evaluation of Computer-Aided Detection (CAD) in Screening Automated Breast Ultrasound Based on Characteristics of CAD Marks and False-Positive Marks.

Lee, Jeongmin / Kang, Bong Joo / Kim, Sung Hun / Park, Ga Eun

Diagnostics (Basel, Switzerland)

2022 Volume 12, Issue 3

Abstract: The present study evaluated the effectiveness of computer-aided detection (CAD) system in screening automated breast ultrasound (ABUS) and analyzed the characteristics of CAD marks and the causes of false-positive marks. A total of 846 women who ... ...

Abstract	The present study evaluated the effectiveness of computer-aided detection (CAD) system in screening automated breast ultrasound (ABUS) and analyzed the characteristics of CAD marks and the causes of false-positive marks. A total of 846 women who underwent ABUS for screening from January 2017 to December 2017 were included. Commercial CAD was used in all ABUS examinations, and its diagnostic performance and efficacy in shortening the reading time (RT) were evaluated. In addition, we analyzed the characteristics of CAD marks and the causes of false-positive marks. A total of 1032 CAD marks were displayed based on the patient and 534 CAD marks on the lesion. Five cases of breast cancer were diagnosed. The sensitivity, specificity, PPV, and NPV of CAD were 60.0%, 59.0%, 0.9%, and 99.6% for 846 patients. In the case of a negative study, it was less time-consuming and easier to make a decision. Among 530 false-positive marks, 459 were identified clearly for pseudo-lesions; the most common cause was marginal shadowing, followed by Cooper's ligament shadowing, peri-areolar shadowing, rib, and skin lesions. Even though CAD does not improve the performance of ABUS and a large number of false-positive marks were detected, the addition of CAD reduces RT, especially in the case of negative screening ultrasound.
Language	English
Publishing date	2022-02-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics12030583
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Article ; Online: Ethanol purification enables high-quality α-phase FAPbI

Kim, Hyun Seo / Yun, Hyun-Sung / Seo, Chae-Eun / Bin Yoo, Soo / Kang, Bong Joo / Jung, Eui Hyuk / Jeon, Nam Joong

Nanoscale horizons

2024

Abstract: Reliable quality and sustainable processes must be developed for commodities to enter the commercial stage. For next-generation photovoltaic applications such as perovskite solar cells, it is essential to manufacture high-quality photoactive ... ...

Abstract	Reliable quality and sustainable processes must be developed for commodities to enter the commercial stage. For next-generation photovoltaic applications such as perovskite solar cells, it is essential to manufacture high-quality photoactive perovskites
Language	English
Publishing date	2024-05-02
Publishing country	England
Document type	Journal Article
ISSN	2055-6764
ISSN (online)	2055-6764
DOI	10.1039/d4nh00061g
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