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  1. AU="Kang, Ji-Hoon"
  2. AU="González-Gómez, Julio César"
  3. AU="Eisinger, Felix"
  4. AU="van Arkel, Gijs H J"
  5. AU="Dukkipati, Haripriya"
  6. AU="Mansoor, Farheen"
  7. AU="Stanton, Clive"
  8. AU=Herholz K AU=Herholz K
  9. AU="Marichal, Axel"
  10. AU="Camon, Ana M"
  11. AU="Randall, Michael D"

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  1. Artikel ; Online: Understanding inactivation of Listeria monocytogenes and Escherichia coli O157:H7 inoculated on romaine lettuce by emulsified thyme essential oil.

    Kang, Ji-Hoon

    Food microbiology

    2022  Band 105, Seite(n) 104013

    Abstract: Effects of thyme essential oil (TEO) emulsion (TEE) with cationic charge formulated using cetylpyridinium chloride (CPC) on attachment strength and inactivation of Listeria monocytogenes and Escherichia coli O157:H7 on romaine lettuce surface were ... ...

    Abstract Effects of thyme essential oil (TEO) emulsion (TEE) with cationic charge formulated using cetylpyridinium chloride (CPC) on attachment strength and inactivation of Listeria monocytogenes and Escherichia coli O157:H7 on romaine lettuce surface were examined in this study. Regardless of the inoculation time (2 h and 24 h), pathogen attachment was stronger on the adaxial surface of the romaine lettuce than on the abaxial surface because of the lower roughness of the former. Moreover, attachment strength increased with increasing inoculation time. TEE washing had the strongest inhibitory effect on pathogen attachment at 2 h when compared with that of TEO, CPC, and sodium hypochlorite (SH), demonstrating a 3.32 and 2.53 log-reduction in the size of the L. monocytogenes and E. coli O157:H7 populations, respectively, compared to the control samples. Additionally, the TEE washing effects were maintained even after inoculation for 24 h, and it decreased attachment to adaxial surface of the samples. These results indicate that TEE could be a good alternative to SH in improving the microbiological safety of romaine lettuce.
    Mesh-Begriff(e) Colony Count, Microbial ; Escherichia coli O157 ; Food Microbiology ; Lactuca/microbiology ; Listeria monocytogenes ; Oils, Volatile/pharmacology ; Thymus Plant
    Chemische Substanzen Oils, Volatile
    Sprache Englisch
    Erscheinungsdatum 2022-03-08
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 50892-5
    ISSN 1095-9998 ; 0740-0020
    ISSN (online) 1095-9998
    ISSN 0740-0020
    DOI 10.1016/j.fm.2022.104013
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Effects of benzalkonium chloride as a cationic surfactant on the physicochemical properties of adlay millet starch films.

    Kim, Minjun / Kang, Ji-Hoon

    Food science and biotechnology

    2023  Band 33, Heft 2, Seite(n) 355–362

    Abstract: The effects of benzalkonium chloride (BC) as a cationic surfactant on the mechanical, water barrier, microstructural, and thermal properties of adlay millet starch (AS) films were investigated in this study. With increasing BC concentration, tensile ... ...

    Abstract The effects of benzalkonium chloride (BC) as a cationic surfactant on the mechanical, water barrier, microstructural, and thermal properties of adlay millet starch (AS) films were investigated in this study. With increasing BC concentration, tensile strength (from 5.93 to 6.15 MPa) and elongation at break (from 41.39 to 45.48%) of AS-BC films significantly increased, whereas their moisture content, water solubility, and water vapor permeability were reduced, indicating water resistance improvement. Fourier transform infrared spectroscopy and scanning electron microscopy analysis showed that BC at concentrations below 1% did not cause noticeable changes in the microstructure of AS-BC films. In addition, the thermal stability of AS-BC films was not affected by BC, indicating good miscibility between AS and BC. Therefore, BC could improve the physicochemical properties of starch films, and AS-BC films developed in this study can be applied as novel biodegradable packaging materials in the food packaging industry.
    Supplementary information: The online version contains supplementary material available at 10.1007/s10068-023-01383-1.
    Sprache Englisch
    Erscheinungsdatum 2023-07-29
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article
    ZDB-ID 2000008-X
    ISSN 2092-6456 ; 1226-7708
    ISSN (online) 2092-6456
    ISSN 1226-7708
    DOI 10.1007/s10068-023-01383-1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Understanding inactivation of Listeria monocytogenes and Escherichia coli O157:H7 inoculated on romaine lettuce by emulsified thyme essential oil

    Kang, Ji-Hoon

    Food microbiology. 2022 Aug., v. 105

    2022  

    Abstract: Effects of thyme essential oil (TEO) emulsion (TEE) with cationic charge formulated using cetylpyridinium chloride (CPC) on attachment strength and inactivation of Listeria monocytogenes and Escherichia coli O157:H7 on romaine lettuce surface were ... ...

    Abstract Effects of thyme essential oil (TEO) emulsion (TEE) with cationic charge formulated using cetylpyridinium chloride (CPC) on attachment strength and inactivation of Listeria monocytogenes and Escherichia coli O157:H7 on romaine lettuce surface were examined in this study. Regardless of the inoculation time (2 h and 24 h), pathogen attachment was stronger on the adaxial surface of the romaine lettuce than on the abaxial surface because of the lower roughness of the former. Moreover, attachment strength increased with increasing inoculation time. TEE washing had the strongest inhibitory effect on pathogen attachment at 2 h when compared with that of TEO, CPC, and sodium hypochlorite (SH), demonstrating a 3.32 and 2.53 log-reduction in the size of the L. monocytogenes and E. coli O157:H7 populations, respectively, compared to the control samples. Additionally, the TEE washing effects were maintained even after inoculation for 24 h, and it decreased attachment to adaxial surface of the samples. These results indicate that TEE could be a good alternative to SH in improving the microbiological safety of romaine lettuce.
    Schlagwörter Escherichia coli O157 ; Listeria monocytogenes ; cetylpyridinium chloride ; emulsions ; essential oils ; food microbiology ; microbiological quality ; pathogens ; romaine lettuce ; roughness ; sodium hypochlorite ; thyme
    Sprache Englisch
    Erscheinungsverlauf 2022-08
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    ZDB-ID 50892-5
    ISSN 1095-9998 ; 0740-0020
    ISSN (online) 1095-9998
    ISSN 0740-0020
    DOI 10.1016/j.fm.2022.104013
    Datenquelle NAL Katalog (AGRICOLA)

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  4. Artikel ; Online: Devitalizing noise-driven instability of entangling logic in silicon devices with bias controls.

    Ryu, Hoon / Kang, Ji-Hoon

    Scientific reports

    2022  Band 12, Heft 1, Seite(n) 15200

    Abstract: The quality of quantum bits (qubits) in silicon is highly vulnerable to charge noise that is omnipresent in semiconductor devices and is in principle hard to be suppressed. For a realistically sized quantum dot system based on a silicon-germanium ... ...

    Abstract The quality of quantum bits (qubits) in silicon is highly vulnerable to charge noise that is omnipresent in semiconductor devices and is in principle hard to be suppressed. For a realistically sized quantum dot system based on a silicon-germanium heterostructure whose confinement is manipulated with electrical biases imposed on top electrodes, we computationally explore the noise-robustness of 2-qubit entangling operations with a focus on the controlled-X (CNOT) logic that is essential for designs of gate-based universal quantum logic circuits. With device simulations based on the physics of bulk semiconductors augmented with electronic structure calculations, we not only quantify the degradation in fidelity of single-step CNOT operations with respect to the strength of charge noise, but also discuss a strategy of device engineering that can significantly enhance noise-robustness of CNOT operations with almost no sacrifice of speed compared to the single-step case. Details of device designs and controls that this work presents can establish practical guideline for potential efforts to secure silicon-based quantum processors using an electrode-driven quantum dot platform.
    Sprache Englisch
    Erscheinungsdatum 2022-09-07
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-19404-0
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Design of high-performance entangling logic in silicon quantum dot systems with Bayesian optimization.

    Kang, Ji-Hoon / Yoon, Taehyun / Lee, Chanhui / Lim, Sungbin / Ryu, Hoon

    Scientific reports

    2024  Band 14, Heft 1, Seite(n) 10080

    Abstract: Device engineering based on computer-aided simulations is essential to make silicon (Si) quantum bits (qubits) be competitive to commercial platforms based on superconductors and trapped ions. Combining device simulations with the Bayesian optimization ( ... ...

    Abstract Device engineering based on computer-aided simulations is essential to make silicon (Si) quantum bits (qubits) be competitive to commercial platforms based on superconductors and trapped ions. Combining device simulations with the Bayesian optimization (BO), here we propose a systematic design approach that is quite useful to procure fast and precise entangling operations of qubits encoded to electron spins in electrode-driven Si quantum dot (QD) systems. For a target problem of the controlled-X (CNOT) logic operation, we employ BO with the Gaussian process regression to evolve design factors of a Si double QD system to the ones that are optimal in terms of speed and fidelity of a CNOT logic driven by a single microwave pulse. The design framework not only clearly contributes to cost-efficient securing of solutions that enhance performance of the target quantum operation, but can be extended to implement more complicated logics with Si QD structures in experimentally unprecedented ways.
    Sprache Englisch
    Erscheinungsdatum 2024-05-02
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-60478-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Cystadenocarcinoma of the intrahepatic bile duct in a dog.

    Kang, Ji-Hoon / Ahn, Seoung-Yob / Yoon, Hun-Young

    The Journal of veterinary medical science

    2022  Band 84, Heft 11, Seite(n) 1514–1519

    Abstract: A 14-year-old spayed female Shih-Tzu was referred to the Veterinary Medical Teaching Hospital of Konkuk University for evaluation of an abdominal mass. In diagnostic imaging, two large cystic masses were identified. The affected liver lobes were ... ...

    Abstract A 14-year-old spayed female Shih-Tzu was referred to the Veterinary Medical Teaching Hospital of Konkuk University for evaluation of an abdominal mass. In diagnostic imaging, two large cystic masses were identified. The affected liver lobes were surgically resected, and the specimens were submitted for histopathological evaluation and immunohistochemical staining. The two cystic lesions were diagnosed as biliary cystadenocarcinoma (BCAC). Recurrence and regional invasion were identified on ultrasonography 36 days postoperatively. The patient died on postoperative day 271. To the best of our knowledge, previously reported case studies of BCAC in dogs presented limited clinical information. In this report, we present a detailed picture comprising a range of clinical information and histopathological examination of BCAC in a dog.
    Mesh-Begriff(e) Animals ; Dogs ; Female ; Bile Duct Neoplasms/diagnostic imaging ; Bile Duct Neoplasms/surgery ; Bile Duct Neoplasms/veterinary ; Bile Ducts, Intrahepatic/pathology ; Cholangiocarcinoma/pathology ; Cholangiocarcinoma/veterinary ; Cystadenocarcinoma/diagnosis ; Cystadenocarcinoma/surgery ; Cystadenocarcinoma/veterinary ; Cystadenoma/diagnosis ; Cystadenoma/pathology ; Cystadenoma/surgery ; Cystadenoma/veterinary ; Dog Diseases/diagnostic imaging ; Dog Diseases/surgery
    Sprache Englisch
    Erscheinungsdatum 2022-10-04
    Erscheinungsland Japan
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 1071753-5
    ISSN 1347-7439 ; 0916-7250
    ISSN (online) 1347-7439
    ISSN 0916-7250
    DOI 10.1292/jvms.22-0370
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Antimicrobial activity of honeybush (Cyclopia intermedia) ethanol extract against foodborne pathogens and its application in washing fresh-cut Swiss chard

    Kang, Ji-Hoon / Song, Kyung Bin

    Food control. 2021 Mar., v. 121

    2021  

    Abstract: This study aimed to determine the antimicrobial activities of honeybush ethanol extract (HBE) against Listeria monocytogenes and Escherichia coli O157:H7, and to define whether it could be used to wash fresh-cut Swiss chard. HPLC analysis showed that HBE ...

    Abstract This study aimed to determine the antimicrobial activities of honeybush ethanol extract (HBE) against Listeria monocytogenes and Escherichia coli O157:H7, and to define whether it could be used to wash fresh-cut Swiss chard. HPLC analysis showed that HBE contained the phenolic compounds, hesperidin, luteolin, kaempferol, mangiferin, and epicatechin, indicating potential antimicrobial activities. The results of disc diffusion tests, time-kill assays, and analyses of the released intracellular compounds revealed that HBE was more effective against L. monocytogenes than E. coli O157:H7. Moreover, scanning electron microscopy images showed that HBE damaged and shriveled the cells of both pathogens. Washing fresh-cut Swiss chard spiked with L. monocytogenes and E. coli O157:H7 with HBE (6 mg/mL) resulted in 2.31–2.67 log reductions in the populations of these bacteria compared with those in the controls. These results were similar to those of washing with sodium hypochlorite (2.20–2.58 log reduction). In addition, washing with HBE maintained the marketable qualities of fresh-cut Swiss chard, namely, color, texture, and electrolyte leakage rates that indicated tissue deterioration. In contrast, the electrolyte leakage rate of the samples washed with sodium hypochlorite increased. These results indicate that HBE could replace sodium hypochlorite and serve as a novel washing agent to ensure the safety and quality of fresh-cut leafy vegetables.
    Schlagwörter Beta vulgaris subsp. vulgaris ; Cyclopia intermedia ; Escherichia coli O157 ; Listeria monocytogenes ; antimicrobial properties ; assays ; bacteria ; cells ; color ; deterioration ; diffusion ; electrolyte leakage ; epicatechin ; ethanol ; food pathogens ; food safety ; green leafy vegetables ; hesperidin ; kaempferol ; luteolin ; phenolic compounds ; population ; sampling ; scanning electron microscopy ; sodium hypochlorite ; testing ; texture ; washing
    Sprache Englisch
    Erscheinungsverlauf 2021-03
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    ZDB-ID 1027805-9
    ISSN 0956-7135
    ISSN 0956-7135
    DOI 10.1016/j.foodcont.2020.107674
    Datenquelle NAL Katalog (AGRICOLA)

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  8. Artikel: Prognostic Value of the Anatomic Region of Metastatic Lymph Nodes in the Current TNM Staging of Gastric Cancer.

    Jeong, Oh / Jung, Mi Ran / Kang, Ji Hoon

    Journal of gastric cancer

    2021  Band 21, Heft 3, Seite(n) 236–245

    Abstract: Purpose: The numeric N stage has replaced the topographic N stage in the current tumor node metastasis (TNM) staging in gastric carcinoma. However, the usefulness of the topographic N stage in the current TNM staging system is uncertain. We aimed to ... ...

    Abstract Purpose: The numeric N stage has replaced the topographic N stage in the current tumor node metastasis (TNM) staging in gastric carcinoma. However, the usefulness of the topographic N stage in the current TNM staging system is uncertain. We aimed to investigate the prognostic value of the topographic N stage in the current TNM staging system.
    Materials and methods: We reviewed the data of 3350 patients with gastric cancer who underwent curative gastrectomy. The anatomic regions of the metastatic lymph nodes (MLNs) were classified into 2 groups: perigastric and extra-perigastric. The prognostic value of the anatomic region was analyzed using a multivariate prognostic model with adjustments for the TNM stage.
    Results: In patients with lymph node metastasis, extra-perigastric metastasis demonstrated significantly worse survival than perigastric metastasis alone (5-year survival rate, 39.6% vs. 73.1%, respectively, P<0.001). Extra-perigastric metastasis demonstrated significantly worse survival within the same pN stage; the multivariate analysis indicated that extra-perigastric metastasis was an independent poor prognostic factor (hazard ratio=1.33; 95% confidence interval=1.01-1.75). The anatomic region of the MLNs improved the goodness-of-fit (likelihood ratio statistics, 4.57; P=0.033) of the prognostic model using the TNM stage.
    Conclusions: The anatomic region of MLNs has an independent prognostic value in the numeric N stage in the current TNM staging of gastric carcinoma.
    Sprache Englisch
    Erscheinungsdatum 2021-08-04
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article
    ZDB-ID 2637180-7
    ISSN 2093-5641 ; 2093-582X
    ISSN (online) 2093-5641
    ISSN 2093-582X
    DOI 10.5230/jgc.2021.21.e22
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Treatment Modality Based Survival in Gastric Carcinoma Patients with Stand-Alone Peritoneal Metastasis: a Case-Control Study.

    Jeong, Oh / Jung, Mi Ran / Kang, Ji Hoon

    Journal of gastric cancer

    2021  Band 21, Heft 2, Seite(n) 122–131

    Abstract: Purpose: To date, there are no promising treatments for gastric carcinoma with peritoneal metastasis. Some researchers have suggested a survival benefit of gastrectomy in select patients. This study investigated the survival of gastric carcinoma ... ...

    Abstract Purpose: To date, there are no promising treatments for gastric carcinoma with peritoneal metastasis. Some researchers have suggested a survival benefit of gastrectomy in select patients. This study investigated the survival of gastric carcinoma patients with stand-alone peritoneal metastasis according to the type of treatment modality.
    Materials and methods: We reviewed the data of 132 patients with gastric carcinoma and stand-alone peritoneal metastasis. We performed gastrectomy when the primary tumor was deemed resectable and systemic chemotherapy was administered. We analyzed patient survival according to the type of treatment, and the prognostic value of gastrectomy was evaluated in univariate and multivariate models.
    Results: Among all patients, 70 underwent gastrectomy plus chemotherapy, 20 underwent gastrectomy alone, 36 underwent chemotherapy alone, and 6 received supportive care. The median patient survival was 13 months. Patients who underwent gastrectomy had significantly longer survival than those who did not undergo gastrectomy (14 vs. 8 months, P<0.001). Patients who received chemotherapy showed significantly longer survival than those who did not (13 vs. 7 months, P=0.032). Patients who underwent gastrectomy plus chemotherapy showed better survival than those who underwent other treatments. In multivariate analysis, gastrectomy was found to be an independent prognostic factor (hazard ratio, 0.52; 95% confidence interval, 0.33-0.82) in addition to chemotherapy.
    Conclusions: Our study showed that patients who underwent gastrectomy plus chemotherapy had the best survival. Although the survival benefit of gastrectomy remains uncertain, it is a favorable prognostic indicator in patients with stand-alone peritoneal metastasis.
    Sprache Englisch
    Erscheinungsdatum 2021-05-20
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article
    ZDB-ID 2637180-7
    ISSN 2093-5641 ; 2093-582X
    ISSN (online) 2093-5641
    ISSN 2093-582X
    DOI 10.5230/jgc.2021.21.e12
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Antibacterial activity of the noni fruit extract against Listeria monocytogenes and its applicability as a natural sanitizer for the washing of fresh-cut produce.

    Kang, Ji-Hoon / Song, Kyung Bin

    Food microbiology

    2019  Band 84, Seite(n) 103260

    Abstract: This study was conducted to investigate the antibacterial activity of the noni fruit extract (NFE) against Listeria monocytogenes (ATCC, 19111 and 19115) and assess its applicability for the washing of fresh-cut produce. Based on the results of the disc ... ...

    Abstract This study was conducted to investigate the antibacterial activity of the noni fruit extract (NFE) against Listeria monocytogenes (ATCC, 19111 and 19115) and assess its applicability for the washing of fresh-cut produce. Based on the results of the disc diffusion test, L. monocytogenes (ATCC, 19111 and 19115) was susceptible to the activity of NFE than other pathogens studied. Additionally, results of the time-kill assay indicated that NFE at a concentration of 0.5-0.7% effectively killed L. monocytogenes within 7 h. Furthermore, analysis of the intracellular components such as nucleic acids and proteins released from the bacterial cells and their SEM imaging revealed that NFE could increase the membrane permeability of cells resulting in their death. Compared to their unwashed samples, washing of romaine lettuce, spinach, and kale with 0.5% NFE gave a reduction of 1.47, 2.28, and 3.38 log CFU/g, respectively against L. monocytogenes (ATCC, 19111 and 19115), which is significantly different to that of NaOCl. A significant correlation was observed between the antibacterial effect induced due to NFE washing with the surface roughness of the fresh-cut produce than its surface hydrophobicity. Moreover, washing with NFE was not found to affect the color of the samples. These results indicated that NFE demonstrates good antibacterial activity against L. monocytogenes and can be used as a natural sanitizer to ensure the microbiological safety of fresh-cut produce.
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Colony Count, Microbial ; Disinfectants/pharmacology ; Food Handling/methods ; Food Microbiology/methods ; Fruit/chemistry ; Lactuca/microbiology ; Listeria monocytogenes/drug effects ; Morinda/chemistry ; Plant Extracts/pharmacology ; Scopoletin/pharmacology ; Spinacia oleracea/microbiology
    Chemische Substanzen Anti-Bacterial Agents ; Disinfectants ; Plant Extracts ; Scopoletin (KLF1HS0SXJ)
    Sprache Englisch
    Erscheinungsdatum 2019-07-05
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 50892-5
    ISSN 1095-9998 ; 0740-0020
    ISSN (online) 1095-9998
    ISSN 0740-0020
    DOI 10.1016/j.fm.2019.103260
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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