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  1. Article ; Online: Fucoidan from Sargassum thunbergii obtained via step gradient ethanol precipitation indicate potential anti-obesity and anti-hepatic steatosis in vitro 3T3-L1 and HepG2 cells and in vivo high-fat diet-induced obesity mice.

    Lee, Hyo-Geun / Jeon, You-Jin / Kang, Min-Cheol

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2023  Volume 174, Page(s) 113686

    Abstract: This study investigated the potential lipid inhibitory and anti-obesity effects of compounds derived from Sargassum thunbergii in vitro and in vivo. We prepared a Celluclast-assisted hydrolysate from Sargassum thunbergii (STC) and three fractional ... ...

    Abstract This study investigated the potential lipid inhibitory and anti-obesity effects of compounds derived from Sargassum thunbergii in vitro and in vivo. We prepared a Celluclast-assisted hydrolysate from Sargassum thunbergii (STC) and three fractional ethanol precipitates (STCF1, STCF2, STCF3). We investigated their proximate composition, and anti-obesity effects in vitro and in vivo. STC and STCFs all significantly reduced intracellular lipid accumulation in PA-treated 3T3-L1 and HepG2 cells. STC, STCF1, and STCF3 had profound anti-obesity effects on high fat diet (HFD)-fed obesity model mice. Oral administration of STC, STCF1, and STCF3 significantly reduced body weight and white adipose tissue (WAT) mass. Furthermore, serum lipid levels were significantly decreased. Additionally, adipose specific hormone levels (adiponectin and fibroblast growth factor-21 (FGF-21)) were significantly decreased, and serum insulin levels were also decreased by STC, STCF1, and STCF3 treatment. A mechanistic study revealed that the adipogenesis and lipolysis associated proteins in epididymal adipose tissue, and free fatty acid oxidation in liver tissues were effectively regulated by STC, STCF1, and STCF3. Overall, our findings show the potent anti-obesity effects of STC, STCF1, and STCF3, achieved by regulation of adipogenesis, lipolysis, and the fatty acid oxidation pathway in HFD-treated obesity model mice.
    MeSH term(s) Mice ; Animals ; Humans ; Diet, High-Fat ; Sargassum ; Adipocytes ; Ethanol/metabolism ; 3T3-L1 Cells ; Hep G2 Cells ; Obesity/metabolism ; Fatty Liver/metabolism ; Adipogenesis ; Anti-Obesity Agents/pharmacology ; Lipids ; Mice, Inbred C57BL
    Chemical Substances fucoidan (9072-19-9) ; Ethanol (3K9958V90M) ; Anti-Obesity Agents ; Lipids
    Language English
    Publishing date 2023-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2023.113686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Catalytic Boosting by Surface-Plasmon-Driven Hot Electrons on Antenna-Reactor Schottky Nanodiodes.

    Kang, Mincheol / Jeon, Beomjoon / Park, Jeong Young

    Nano letters

    2023  Volume 23, Issue 11, Page(s) 5116–5122

    Abstract: Significant research has focused on enhancing catalytic performance through solar energy conversion, and the design of photocatalysis incorporating surface plasmons is drawing considerable attention as a highly competitive catalyst system. Although the ... ...

    Abstract Significant research has focused on enhancing catalytic performance through solar energy conversion, and the design of photocatalysis incorporating surface plasmons is drawing considerable attention as a highly competitive catalyst system. Although the hot electron process is the primary mechanism in plasmonic photocatalysis, the precise function of hot electron transport in catalytic reactions remains unclear due to the absence of direct measurement. Here, we demonstrate the intrinsic relationship between surface-plasmon-driven hot electrons and catalytic activity during hydrogen oxidation, utilizing catalytic Schottky nanodiodes (Pt/Ag/TiO
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c01037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Glyoxal-derived advanced glycation end products (GO-AGEs) with UVB critically induce skin inflammaging: in vitro and in silico approaches.

    Sultana, Razia / Parveen, Amna / Kang, Min-Cheol / Hong, Seong-Min / Kim, Sun Yeou

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1843

    Abstract: Advanced glycation end products (AGEs) have potential implications on several diseases including skin inflammation and aging. AGEs formation can be triggered by several factors such as UVB, glyoxal and methylglyoxal etc. However, little attention has ... ...

    Abstract Advanced glycation end products (AGEs) have potential implications on several diseases including skin inflammation and aging. AGEs formation can be triggered by several factors such as UVB, glyoxal and methylglyoxal etc. However, little attention has been paid to glyoxal-derived AGEs (GO-AGEs) and UVB-induced skin inflammaging, with none have investigated together. This study aimed to investigate the possible role of GO-AGEs and UVB in skin inflammaging focusing on revealing its molecular mechanisms. The effects of GO-AGEs in the presence or absence of UVB were studied by using enzyme linked immunosorbent assay, western blotting, qPCR, flow cytometry and in silico approaches. In HaCaT cells, GO-AGEs in the presence of UVB irradiation (125 mJ/cm
    MeSH term(s) Humans ; Glyoxal ; Molecular Docking Simulation ; Skin ; Dermatitis ; Interleukin-1beta ; Glycation End Products, Advanced
    Chemical Substances Glyoxal (50NP6JJ975) ; Interleukin-1beta ; Glycation End Products, Advanced
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52037-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Methods to Isolate Muscle Stem Cells for Cell-Based Cultured Meat Production: A Review.

    Lee, Jae-Hoon / Kim, Tae-Kyung / Kang, Min-Cheol / Park, Minkyung / Choi, Yun-Sang

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 5

    Abstract: Cultured meat production relies on various cell types, including muscle stem cells (MuSCs), embryonic stem cell lines, induced pluripotent cell lines, and naturally immortalized cell lines. MuSCs possess superior muscle differentiation capabilities ... ...

    Abstract Cultured meat production relies on various cell types, including muscle stem cells (MuSCs), embryonic stem cell lines, induced pluripotent cell lines, and naturally immortalized cell lines. MuSCs possess superior muscle differentiation capabilities compared to the other three cell lines, making them key for cultured meat development. Therefore, to produce cultured meat using MuSCs, they must first be effectively separated from muscles. At present, the methods used to isolate MuSCs from muscles include (1) the pre-plating method, using the ability of cells to adhere differently, which is a biological characteristic of MuSCs; (2) the density gradient centrifugation method, using the intrinsic density difference of cells, which is a physical characteristic of MuSCs; and (3) fluorescence- and magnetic-activated cell sorting methods, using the surface marker protein on the cell surface of MuSCs, which is a molecular characteristic of MuSCs. Further efficient and valuable methods for separating MuSCs are expected to be required as the cell-based cultured meat industry develops. Thus, we take a closer look at the four methods currently in use and discuss future development directions in this review.
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14050819
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effective Emoticon Suggestion Technique Based on Active Emotional Input Using Facial Expressions and Heart Rate Signals.

    Kim, Jesung / Kang, Mincheol / Seo, Bohun / Hong, Jeongkyu / Kim, Soontae

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 9

    Abstract: The evolution of mobile communication technology has brought about significant changes in the way people communicate. However, the lack of nonverbal cues in computer-mediated communication can make the accurate interpretation of emotions difficult. This ... ...

    Abstract The evolution of mobile communication technology has brought about significant changes in the way people communicate. However, the lack of nonverbal cues in computer-mediated communication can make the accurate interpretation of emotions difficult. This study proposes a novel approach for using emotions as active input in mobile systems. This approach combines psychological and neuroscientific principles to accurately and comprehensively assess an individual's emotions for use as input in mobile systems. The proposed technique combines facial and heart rate information to recognize users' five prime emotions, which can be implemented on mobile devices using a front camera and a heart rate sensor. A user evaluation was conducted to verify the efficacy and feasibility of the proposed technique, and the results showed that users could express emotions faster and more accurately, with average recognition accuracies of 90% and 82% for induced and intended emotional expression, respectively. The proposed technique has the potential to enhance the user experience and provide more personalized and dynamic interaction with mobile systems.
    MeSH term(s) Humans ; Facial Expression ; Heart Rate ; Emotions/physiology ; Communication ; Cues
    Language English
    Publishing date 2023-05-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23094460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Fucoidan from Sargassum thunbergii obtained via step gradient ethanol precipitation indicate potential anti-obesity and anti-hepatic steatosis in vitro 3T3-L1 and HepG2 cells and in vivo high-fat diet-induced obesity mice

    Lee, Hyo-Geun / Jeon, You-Jin / Kang, Min-Cheol

    Food and Chemical Toxicology. 2023 Apr., v. 174 p.113686-

    2023  

    Abstract: This study investigated the potential lipid inhibitory and anti-obesity effects of compounds derived from Sargassum thunbergii in vitro and in vivo. We prepared a Celluclast-assisted hydrolysate from Sargassum thunbergii (STC) and three fractional ... ...

    Abstract This study investigated the potential lipid inhibitory and anti-obesity effects of compounds derived from Sargassum thunbergii in vitro and in vivo. We prepared a Celluclast-assisted hydrolysate from Sargassum thunbergii (STC) and three fractional ethanol precipitates (STCF1, STCF2, STCF3). We investigated their proximate composition, and anti-obesity effects in vitro and in vivo. STC and STCFs all significantly reduced intracellular lipid accumulation in PA-treated 3T3-L1 and HepG2 cells. STC, STCF1, and STCF3 had profound anti-obesity effects on high fat diet (HFD)-fed obesity model mice. Oral administration of STC, STCF1, and STCF3 significantly reduced body weight and white adipose tissue (WAT) mass. Furthermore, serum lipid levels were significantly decreased. Additionally, adipose specific hormone levels (adiponectin and fibroblast growth factor-21 (FGF-21)) were significantly decreased, and serum insulin levels were also decreased by STC, STCF1, and STCF3 treatment. A mechanistic study revealed that the adipogenesis and lipolysis associated proteins in epididymal adipose tissue, and free fatty acid oxidation in liver tissues were effectively regulated by STC, STCF1, and STCF3. Overall, our findings show the potent anti-obesity effects of STC, STCF1, and STCF3, achieved by regulation of adipogenesis, lipolysis, and the fatty acid oxidation pathway in HFD-treated obesity model mice.
    Keywords Sargassum thunbergii ; adipogenesis ; adiponectin ; beta oxidation ; blood lipids ; blood serum ; epididymis ; ethanol ; fibroblasts ; free fatty acids ; fucoidan ; high fat diet ; hydrolysates ; insulin ; lipids ; lipolysis ; liver ; obesity ; oral administration ; proximate composition ; toxicology ; white adipose tissue ; Polysaccharides ; Anti-obesity ; Anti-hepatic steatosis
    Language English
    Dates of publication 2023-04
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2023.113686
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Plasmonic hot carrier-driven photoelectrochemical water splitting on antenna-reactor Pt/Ag/TiO

    Kim, Heeyoung / Park, Hyewon / Kang, Mincheol / Park, Jeong Young

    The Journal of chemical physics

    2022  Volume 157, Issue 8, Page(s) 84701

    Abstract: Plasmonic photoelectrochemical (PEC) water splitting has excited immense interest, as it can overcome the intrinsic limitations of semiconductors, in terms of light absorption, by the localized-surface plasmon resonances effect. Here, to get insight into ...

    Abstract Plasmonic photoelectrochemical (PEC) water splitting has excited immense interest, as it can overcome the intrinsic limitations of semiconductors, in terms of light absorption, by the localized-surface plasmon resonances effect. Here, to get insight into the role of plasmonic hot carriers in plasmonic water splitting, a rational design of an antenna-reactor type Pt/Ag/TiO
    Language English
    Publishing date 2022-08-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0097713
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Effect of Crude Polysaccharides from

    Lee, Jae-Hoon / Kim, Tae-Kyung / Kang, Min-Cheol / Park, Min-Kyung / Park, Sang-Hun / Choi, Jung-Seok / Choi, Yun-Sang

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 4

    Abstract: ... Ecklonia ... ...

    Abstract Ecklonia cava
    Language English
    Publishing date 2024-02-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13040563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Effects of myofibril-palatinose conjugate as a phosphate substitute on meat emulsion quality.

    Kim, Tae-Kyung / Kim, Yun Jeong / Kang, Min-Cheol / Cha, Ji Yoon / Kim, Yea-Ji / Choi, Yoo-Jeong / Jung, Samooel / Choi, Yun-Sang

    Heliyon

    2024  Volume 10, Issue 7, Page(s) e28315

    Abstract: The objective of this study was to investigate a replacement for phosphate in meat products. Protein structural modification was employed in this study, and grafted myofibrillar protein (MP) with palatinose was added to meat emulsion without phosphate. ... ...

    Abstract The objective of this study was to investigate a replacement for phosphate in meat products. Protein structural modification was employed in this study, and grafted myofibrillar protein (MP) with palatinose was added to meat emulsion without phosphate. Here, 0.15% of sodium polyphosphate (SPP) was replaced by the same (0.15%) concentration and double (0.3%) the concentration of grafted MP. Although the thermal stability was decreased, the addition of transglutaminase could increase stability. The rheological properties and pH also increased with the addition of grafted MP and transglutaminase. The addition of grafted protein could be perceived by the naked eye by observing a color difference before cooking, but it was not easy to detect after cooking. The cooking loss, emulsion stability, water holding capacity, lipid oxidation, and textural properties improved with the addition of grafted MP. However, the excessive addition of grafted MP and transglutaminase was not recommended to produce a high quality of phosphate replaced meat emulsion, and 0.15% was identified as a suitable addition ratio of grafted MP.
    Language English
    Publishing date 2024-03-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e28315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The effects of different extraction methods on essential oils from orange and tangor: From the peel to the essential oil.

    Park, Min Kyung / Cha, Ji Yoon / Kang, Min-Cheol / Jang, Hae Won / Choi, Yun-Sang

    Food science & nutrition

    2023  Volume 12, Issue 2, Page(s) 804–814

    Abstract: Citrus fruits are largely consumed due to their unique and pleasant aromas. ...

    Abstract Citrus fruits are largely consumed due to their unique and pleasant aromas.
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703010-6
    ISSN 2048-7177
    ISSN 2048-7177
    DOI 10.1002/fsn3.3785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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