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  1. Article: [Research prospect of preclinical model construction and precision therapy in ameloblastoma].

    Kang, X D / Sun, L L / Zhang, Z Y / Sun, S Y

    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

    2023  Volume 58, Issue 8, Page(s) 844–851

    Abstract: Ameloblastoma (AM) is a benign odontogenic tumor with unknown etiology. It is prone to recurrence and has a potential for malignant transformation. Patients often show high rates of relapse after curettage, or suffer from structural and functional damage ...

    Abstract Ameloblastoma (AM) is a benign odontogenic tumor with unknown etiology. It is prone to recurrence and has a potential for malignant transformation. Patients often show high rates of relapse after curettage, or suffer from structural and functional damage of jaw after partial resection. Whole-genome sequencing data revealed that BRAF mutations and SMO mutations were common and likely to be mutually exclusive in AM. It was also reported that BRAF inhibitors were effective in several patients carrying BRAF
    MeSH term(s) Humans ; Animals ; Mice ; Ameloblastoma/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Mice, Nude ; Neoplasm Recurrence, Local ; Odontogenic Tumors ; Mutation
    Chemical Substances Proto-Oncogene Proteins B-raf (EC 2.7.11.1)
    Language Chinese
    Publishing date 2023-08-27
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 1027950-7
    ISSN 1002-0098
    ISSN 1002-0098
    DOI 10.3760/cma.j.cn112144-20230703-00264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2507: Show issues Location:
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  2. Article: [HBV genotyping based on key epitopes of PreS1 antigen and its correlation with genotyping by full-length PreS1 sequencing].

    Zhang, X C / Li, Y M / Li, J Y / Kang, X D / He, X Y / Niu, J Q / Wen, X Y / Liu, Z N

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2018  Volume 26, Issue 5, Page(s) 371–376

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Amino Acid Sequence ; China ; Epitopes ; Genotype ; Hepatitis B ; Hepatitis B Antibodies ; Hepatitis B Surface Antigens ; Hepatitis B virus ; Humans ; Polymerase Chain Reaction
    Chemical Substances Epitopes ; Hepatitis B Antibodies ; Hepatitis B Surface Antigens
    Language Chinese
    Publishing date 2018-08-27
    Publishing country China
    Document type Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.issn.1007-3418.2018.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Application of Quantitative Analysis of Diatoms in Lung Tissue for the Diagnosis of Drowning of Experimental Animals.

    Zhao, J / Luo, Y Z / Wang, Y Z / Xiao, C / Shi, H / Hu, S L / Kang, X D / Xu, Q Y / Cheng, J D / Liu, C

    Fa yi xue za zhi

    2019  Volume 35, Issue 6, Page(s) 706–709

    Abstract: Abstract: Objective To discuss the application value of diatom examination in lung tissue for the forensic diagnosis of drowning. Methods The experimental animals were divided randomly into drowning, postmortem submergence and dying on land group. ... ...

    Abstract Abstract: Objective To discuss the application value of diatom examination in lung tissue for the forensic diagnosis of drowning. Methods The experimental animals were divided randomly into drowning, postmortem submergence and dying on land group. Diatoms in lung tissue and drowning fluid were analyzed quantitatively by microwave digestion-vacuum filtration-automated scanning electron microscopy diatom examination method. The ratios of content of diatoms in lung tissue and drowning fluid （
    MeSH term(s) Animals ; Autopsy ; Diatoms/cytology ; Drowning/diagnosis ; Lung ; Microscopy, Electron, Scanning ; Rabbits ; Random Allocation ; Swine
    Language Chinese
    Publishing date 2019-12-25
    Publishing country China
    Document type Journal Article
    ISSN 1004-5619
    ISSN 1004-5619
    DOI 10.12116/j.issn.1004-5619.2019.06.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Research Progress on Determination of Drowning Site].

    Zhao, J / Xu, L W / Kang, X D / Shi, H / Liu, C / Hu, S L / Yang, X Y / Xu, Q Y / Cheng, J D / Ai, M

    Fa yi xue za zhi

    2018  Volume 34, Issue 1, Page(s) 55–59

    Abstract: The bodies found in water are one of the most common types in forensic practice. The discovery site of the body is often not the drowning site. However, the determination of drowning site is vital for the identification of victim. Inorganic particles and ...

    Abstract The bodies found in water are one of the most common types in forensic practice. The discovery site of the body is often not the drowning site. However, the determination of drowning site is vital for the identification of victim. Inorganic particles and planktons, such as granular impurities, diatoms and bacteria, are valuable markers for the diagnosis of drowning. By comparing the granular impurities and planktons in tissues and suspicious drowning mediums, the drowning site can be concluded based on their similarity of types and distribution, which has practical applied value. In this paper, the research progress on determination of drowning site is summarized to provide reference for the peers.
    MeSH term(s) Diatoms ; Drowning/pathology ; Forensic Pathology/trends ; Fresh Water ; Humans ; Plankton ; Water
    Chemical Substances Water (059QF0KO0R)
    Language Chinese
    Publishing date 2018-02
    Publishing country China
    Document type Journal Article ; Review
    ISSN 1004-5619
    ISSN 1004-5619
    DOI 10.3969/j.issn.1004-5619.2018.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [The design of a multifunctional mobile operating table].

    Kang, X D / Ye, Y / Xia, Z Q

    Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation

    2001  Volume 25, Issue 1, Page(s) 34–35

    Abstract: This article introduces the principles and design of a multifunctional medical table which could be used to immobilize patient from/to bed to/from table, and it can also be used as an operating table. So the dangerous and serious patients can get ... ...

    Abstract This article introduces the principles and design of a multifunctional medical table which could be used to immobilize patient from/to bed to/from table, and it can also be used as an operating table. So the dangerous and serious patients can get continuous servo and monitoring during the transfer. The hydraulic pressure lifter, machinery transmission, flat movement and asymmetry structure are employed in the product.
    MeSH term(s) Durable Medical Equipment ; Equipment Design ; Surgical Equipment
    Language Chinese
    Publishing date 2001-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1671-7104
    ISSN 1671-7104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A mutation in the Kit gene leads to novel gonadal phenotypes in both heterozygous and homozygous mice.

    Wu, B J / Yin, L J / Yin, H P / Ying, X S / Yang, W W / Zeng, Y M / Zhu, J / Kang, X D / Liu, G J / Yu, L P / Gu, M E / Wu, P L

    Hereditas

    2010  Volume 147, Issue 2, Page(s) 62–69

    Abstract: The direct sequencing of the Kit cDNA obtained from mutant mice was used to reveal the molecular nature of the W(-3Bao) ENU-induced mutation. There was a T to A transversion at the 441st nucleotide in the W(-3Bao) open reading frame (ORF), which ... ...

    Abstract The direct sequencing of the Kit cDNA obtained from mutant mice was used to reveal the molecular nature of the W(-3Bao) ENU-induced mutation. There was a T to A transversion at the 441st nucleotide in the W(-3Bao) open reading frame (ORF), which introduced a pre-mature termination codon at residue 147. The gross embryonic development, hematopoiesis and spermatogenesis were examined in the mutant mice. There was no visible difference among the W(-3Bao/+), W(-3Bao/3Bao) and wild type embryos before embryonic day 12.5. W(-3Bao/3Bao) embryos appeared pale after E14.5 and dwarf after E16.5. An extremely low level of hematochrome and large red blood cells were found in W(-3Bao/3Bao) 18.5 days old embryos, leading to the stillbirth of the homozygotes. In 18.5 days old embryos the spermatogonia of W(-3Bao/3Bao) embryos did not migrate to the contorted seminiferous tubules properly, but instead were found in the interstitial tissue. The spermatogonia of W(-3Bao/+) or W(+/+) mice were present in both the interstitial tissue and contorted seminiferous tubules. In the adult male hetereozygotes, there are contorted seminiferous tubules with no spermatogonia, suggesting that the migration defect was dominant. In female W(-3Bao/3Bao) ovaries, primordial follicles were absent while primordial follicles appeared clearly in the ovaries of W(-3Bao/+) or W(+/+) mice. With a nonsense mutation in the Kit gene, W(-3Bao/+) mice show white spotting and an abnormal development of the contorted seminiferous tubules and W(-3Bao/3Bao) mice are stillborn due to severe macrocytic anemia, and have abnormal genital glands in both the male and female.
    MeSH term(s) Animals ; Mice ; Mutation ; Phenotype ; Proto-Oncogene Proteins c-kit/genetics
    Chemical Substances Proto-Oncogene Proteins c-kit (EC 2.7.10.1)
    Language English
    Publishing date 2010-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 214294-6
    ISSN 1601-5223 ; 0018-0661
    ISSN (online) 1601-5223
    ISSN 0018-0661
    DOI 10.1111/j.1601-5223.2009.02131.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ub I Zs.89: Show issues Location:
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