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  1. Article ; Online: Native point defects in antiperovskite Ba

    Kang, Youngho

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 14, Page(s) 9800–9806

    Abstract: We present a theoretical investigation on intrinsic defects of hexagonal antiperovskite ... ...

    Abstract We present a theoretical investigation on intrinsic defects of hexagonal antiperovskite Ba
    Language English
    Publishing date 2023-04-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp00619k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Landscape of NcRNAs involved in drug resistance of breast cancer.

    Kang, Yujuan

    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

    2023  Volume 25, Issue 7, Page(s) 1869–1892

    Abstract: Breast cancer (BC) leads to the most amounts of deaths among women. Chemo-, endocrine-, and targeted therapies are the mainstay drug treatments for BC in the clinic. However, drug resistance is a major obstacle for BC patients, and it leads to poor ... ...

    Abstract Breast cancer (BC) leads to the most amounts of deaths among women. Chemo-, endocrine-, and targeted therapies are the mainstay drug treatments for BC in the clinic. However, drug resistance is a major obstacle for BC patients, and it leads to poor prognosis. Accumulating evidences suggested that noncoding RNAs (ncRNAs) are intricately linked to a wide range of pathological processes, including drug resistance. Till date, the correlation between drug resistance and ncRNAs is not completely understood in BC. Herein, we comprehensively summarized a dysregulated ncRNAs landscape that promotes or inhibits drug resistance in chemo-, endocrine-, and targeted BC therapies. Our review will pave way for the effective management of drug resistance by targeting oncogenic ncRNAs, which, in turn will promote drug sensitivity of BC in the future.
    MeSH term(s) Humans ; Female ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; RNA, Long Noncoding/genetics ; RNA, Untranslated/genetics ; Drug Resistance, Neoplasm/genetics
    Chemical Substances RNA, Long Noncoding ; RNA, Untranslated
    Language English
    Publishing date 2023-04-17
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2397359-6
    ISSN 1699-3055 ; 1699-048X
    ISSN (online) 1699-3055
    ISSN 1699-048X
    DOI 10.1007/s12094-023-03189-3
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    Zs.A 6644: Show issues Location:
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  3. Article: [Ascites CD100 levels and immunomodulation effects in the peripheral blood of patients with liver cirrhosis combined with spontaneous bacterial peritonitis].

    Hou, H R / Kang, Y

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2023  Volume 31, Issue 2, Page(s) 138–146

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Ascites/immunology ; Immunomodulation/immunology ; Antigens, CD/blood ; Antigens, CD/immunology ; Liver Cirrhosis/blood ; Liver Cirrhosis/complications ; Liver Cirrhosis/immunology ; Peritonitis/blood ; Peritonitis/complications ; Peritonitis/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Humans
    Chemical Substances CD100 antigen ; Antigens, CD
    Language Chinese
    Publishing date 2023-05-03
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20220314-00108
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  4. Article ; Online: Evaluating the cutoff score of the advanced practice nurse certification examination in Korea.

    Kang, Younhee

    Nurse education in practice

    2022  Volume 63, Page(s) 103407

    Abstract: Aim: This study aimed to evaluate the cutoff score of the Advanced Practice Nurse (APN) certification examination determined using two standard-setting methods and to compare it with the current score.: Background: The APN qualification is ... ...

    Abstract Aim: This study aimed to evaluate the cutoff score of the Advanced Practice Nurse (APN) certification examination determined using two standard-setting methods and to compare it with the current score.
    Background: The APN qualification is established by passing a certification examination. However, the method of determining the passing criterion is different among countries. In Korea, the passing criterion has been predetermined as 60% of the total score or above without any theoretical or empirical basis.
    Design: In this study, two typical and popular standard-setting methods, the modified Angoff and Bookmark methods, were used to determine the passing criterion of the APN certification examination.
    Methods: The performance data of a gerontological APN certification examination were used to conduct standard setting with both the modified Angoff and Bookmark methods. The total number of examinees in the dataset was 121. Item analysis with a 2-parameter logistic model was performed based on the item response theory using the Bilog-MG3.0 program. A total of 5 raters in APN education and clinical nursing practice were selected.
    Results: The modified Angoff and Bookmark methods gave cutoff scores of 113 and 110.5 with passing ratios of 52.9% and 57.0%, respectively. These results were different from the conventional cutoff score of 90 with a passing ratio of 93.4%.
    Conclusion: The present arbitrary fixed cutoff score should be reconsidered to improve the robustness of the APN qualification and standard-setting methods should be employed to determine an adequate cutoff score for the APN certification examination to ensure the competency of APNs in providing advanced care.
    MeSH term(s) Certification ; Educational Measurement/methods ; Humans ; Republic of Korea
    Language English
    Publishing date 2022-07-05
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2058575-5
    ISSN 1873-5223 ; 1471-5953
    ISSN (online) 1873-5223
    ISSN 1471-5953
    DOI 10.1016/j.nepr.2022.103407
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5492: Show issues Location:
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  5. Article: [Validation of a C57/BL6J mouse model of focal cerebral ischemia established by electrocoagulation of the middle cerebral artery].

    Kang, Y / Tang, D / Zhang, J / Xia, Q

    Nan fang yi ke da xue xue bao = Journal of Southern Medical University

    2024  Volume 44, Issue 1, Page(s) 100–107

    Abstract: Objective: To modify the method for establishing mouse models of middle cerebral artery occlusion (MCAO)-induced focal cerebral ischemia using electrocoagulation.: Methods: Forty-six C57/BL6J male mice were divided into MCAO model group (: Results!# ...

    Abstract Objective: To modify the method for establishing mouse models of middle cerebral artery occlusion (MCAO)-induced focal cerebral ischemia using electrocoagulation.
    Methods: Forty-six C57/BL6J male mice were divided into MCAO model group (
    Results: The mice in the model group showed significantly reduced cerebral blood flow in the MCA on the ischemic side and obvious neurological deficits with increased forelimb use asymmetry on days 1, 7 and 14 after modeling (
    Conclusion: We successfully prepared mouse models of MCAO using a modified method by changing the electrocoagulation location from the distal location of the junction between the MCA and the inferior cerebral vein to a 2 mm segment medial to the junction between the MCA and the olfactory bundle.
    MeSH term(s) Male ; Mice ; Animals ; Middle Cerebral Artery/surgery ; Brain-Derived Neurotrophic Factor ; Brain Ischemia ; Infarction, Middle Cerebral Artery ; Staining and Labeling ; Disease Models, Animal
    Chemical Substances Brain-Derived Neurotrophic Factor
    Language Chinese
    Publishing date 2024-01-31
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2250951-3
    ISSN 1673-4254
    ISSN 1673-4254
    DOI 10.12122/j.issn.1673-4254.2024.01.12
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    Zs.A 6344: Show issues Location:
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  6. Article: [Value of transnasal high-flow oxygen therapy and noninvasive ventilation in the management of acute respiratory distress syndrome].

    Yang, S / Yang, J / Kang, Y

    Zhonghua yi xue za zhi

    2024  Volume 104, Issue 15, Page(s) 1230–1235

    Abstract: Acute respiratory distress syndrome (ARDS) is one of the most common syndromes in the intensive care unit, with a high mortality and morbidity. Refractory hypoxia is the typical feature of ARDS, and improving hypoxia is the key to the treatment of ARDS. ... ...

    Abstract Acute respiratory distress syndrome (ARDS) is one of the most common syndromes in the intensive care unit, with a high mortality and morbidity. Refractory hypoxia is the typical feature of ARDS, and improving hypoxia is the key to the treatment of ARDS. Due to the rapid progression of ARDS, invasive ventilation is usually used to improve hypoxia. But in recent years, with the extending of the understanding of ARDS and the development of non-invasive oxygen therapy, high flow nasal oxygen (HFNO) and non-invasive ventilation (NIV) are gradually used in ARDS. Therefore, we reviewed the role of HFNO and NIV in ARDS in this paper.
    MeSH term(s) Humans ; Noninvasive Ventilation ; Respiration, Artificial ; Oxygen ; Respiratory Distress Syndrome/therapy ; Hypoxia/therapy ; Respiratory Insufficiency/therapy
    Chemical Substances Oxygen (S88TT14065)
    Language Chinese
    Publishing date 2024-04-18
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20231023-00865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Molecular identification of

    Kang, Yong

    Mitochondrial DNA. Part B, Resources

    2021  Volume 6, Issue 4, Page(s) 1525–1535

    Abstract: ... ...

    Abstract Aquilaria
    Language English
    Publishing date 2021-04-26
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2021.1914210
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  8. Article ; Online: How important is EMT for cancer metastasis?

    Celià-Terrassa, Toni / Kang, Yibin

    PLoS biology

    2024  Volume 22, Issue 2, Page(s) e3002487

    Abstract: Epithelial-to-mesenchymal transition (EMT), a biological phenomenon of cellular plasticity initially reported in embryonic development, has been increasingly recognized for its importance in cancer progression and metastasis. Despite tremendous progress ... ...

    Abstract Epithelial-to-mesenchymal transition (EMT), a biological phenomenon of cellular plasticity initially reported in embryonic development, has been increasingly recognized for its importance in cancer progression and metastasis. Despite tremendous progress being made in the past 2 decades in our understanding of the molecular mechanism and functional importance of EMT in cancer, there are several mysteries around EMT that remain unresolved. In this Unsolved Mystery, we focus on the variety of EMT types in metastasis, cooperative and collective EMT behaviors, spatiotemporal characterization of EMT, and strategies of therapeutically targeting EMT. We also highlight new technical advances that will facilitate the efforts to elucidate the unsolved mysteries of EMT in metastasis.
    MeSH term(s) Humans ; Neoplasms/pathology ; Epithelial-Mesenchymal Transition ; Embryonic Development ; Neoplasm Metastasis
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2126776-5
    ISSN 1545-7885 ; 1544-9173
    ISSN (online) 1545-7885
    ISSN 1544-9173
    DOI 10.1371/journal.pbio.3002487
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    Zs.A 6193: Show issues Location:
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  9. Article ; Online: Exploring the connection between caffeine intake and constipation: a cross-sectional study using national health and nutrition examination survey data.

    Kang, Yulong / Yan, Jin

    BMC public health

    2024  Volume 24, Issue 1, Page(s) 3

    Abstract: Background: Caffeine has been reported to increase gastrointestinal motility and change intestinal microbiota. Constipation may be caused by colonic motor dysfunction and colonic microbiomeis disturbances. In this study, we aimed to explore the ... ...

    Abstract Background: Caffeine has been reported to increase gastrointestinal motility and change intestinal microbiota. Constipation may be caused by colonic motor dysfunction and colonic microbiomeis disturbances. In this study, we aimed to explore the association between caffeine intake and constipation.
    Methods: This was a cross-sectional study based on the National Health and Nutrition Examination Survey (NHANES). Caffeine intake was assessed using 24-h dietary recall method, and constipation was defined based on stool consistency or stool frequency. Logistic regression analysis was used to assess the association between caffeine intake and constipation, and results were expressed as odds ratio (OR) with 95% confidence intervals (95%CI). Subgroup analysis was performed based on age.
    Results: A total of 13,816 participants were finally included for analysis. After adjusting potential confounders, high intake of caffeine was found to be associated with the low odds of constipation (Q3: OR = 0.60, 95%CI: 0.49-0.74; Q4: OR = 0.77, 95%CI: 0.59-0.99; Q5: OR = 0.72, 95%CI: 0.56-0.92). The similar association was found in young people and middle-age people (P < 0.05).
    Conclusion: High caffeine intake was associated with the low odds of constipation. Our finding indicated that individuals should develop consciousness and habit of consuming caffeinated foods and drinks to prevent and relief the constipation.
    MeSH term(s) Middle Aged ; Humans ; Adolescent ; Caffeine/adverse effects ; Nutrition Surveys ; Cross-Sectional Studies ; Constipation/chemically induced ; Constipation/epidemiology ; Diet/adverse effects
    Chemical Substances Caffeine (3G6A5W338E)
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-17502-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Why Are Dying Individuals Stigmatized and Socially Avoided? Psychological Explanations.

    Kang, Youngjin

    Journal of social work in end-of-life & palliative care

    2021  Volume 17, Issue 4, Page(s) 317–348

    Abstract: Extant research on the topic of death and dying in modern society frequently includes the observation that death is now rendered invisible, and dying individuals are stigmatized and socially avoided. The current research speculated that lack of contact ... ...

    Abstract Extant research on the topic of death and dying in modern society frequently includes the observation that death is now rendered invisible, and dying individuals are stigmatized and socially avoided. The current research speculated that lack of contact with a dying individual may promote negative perceptions of the dying, and this may in turn lead to further avoidance of them. Three studies were conducted: The first study examined how frequently the current U.S. participants had social contact with a dying individual; the second study investigated what perceptions they have of the dying, and the third study tested for potential causal links between negative perceptions of the dying and social avoidance of them. The results indicated: Only a small number of the U.S. participants ever had frequent social contact with a dying individual outside their family; they, nevertheless, shared several common negative perceptions of the dying; and those negative perceptions exerted different effects on one's avoidant attitude toward a dying individual-only making males more avoidant, especially in a physically close social relationship. Two concepts, medicalization and masculinism, were suggested as possible explanations for why dying individuals are stigmatized and avoided in modern society.
    MeSH term(s) Attitude to Death ; Humans ; Male
    Language English
    Publishing date 2021-05-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2179023-1
    ISSN 1552-4264 ; 1552-4256
    ISSN (online) 1552-4264
    ISSN 1552-4256
    DOI 10.1080/15524256.2021.1930330
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