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  1. Article ; Online: Machine Learning-Based Air-to-Ground Channel Model Selection Method for UAV Communications Using Digital Surface Model Data.

    Kang, Young-Eun / Jung, Young-Ho

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 23

    Abstract: This paper proposes an automatic air-to-ground (A2G) channel model selection method based on machine learning (ML) using digital surface model (DSM) terrain data. In order to verify whether a communication network for a new non-terrestrial user service ... ...

    Abstract This paper proposes an automatic air-to-ground (A2G) channel model selection method based on machine learning (ML) using digital surface model (DSM) terrain data. In order to verify whether a communication network for a new non-terrestrial user service such as Urban Air Mobility (UAM) satisfies the required performance, it is necessary to perform a simulation reflecting the characteristics of the corresponding terrain environments as accurately as possible. For this simulation, A2G channel models corresponding to various terrain environments and a method of automatically classifying the terrain type of the simulation area must be provided. Many A2G channel models based on actual measurement results exist, but the practical automatic topography classification method still needs to be developed. This paper proposes the first practical automatic topography classification method using a two-step neural network-based classifier utilizing various geographic feature data as input. Since there is no open topography dataset to evaluate the accuracy of the proposed method, we built a new dataset for five topography classes that reflect the characteristics of Korea's topography, which is also a contribution of our study. The simulation results using the new data set show that the proposed ML-based method could increase the selection accuracy compared to the technique for direct classification by humans or the existing cross-correlation-based classification method. Since the proposed method utilizes the DSM data, open to the public, it can easily reflect the different terrain characteristics of each country. Therefore, the proposed method can be effectively used in the realistic performance evaluation of new non-terrestrial communication networks utilizing vast airspace such as UAM or 6G mobile communications.
    Language English
    Publishing date 2022-11-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22239234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Analyzing the characteristics of mission statements in Korean medical schools based on the Korean Doctor's Role framework.

    Kang, Ye Ji / Lee, Soomin / Lee, Hyo Jeong / Kim, Do-Hwan

    Korean journal of medical education

    2024  Volume 36, Issue 1, Page(s) 99–104

    Abstract: Purpose: This study assessed the alignment between Korean medical schools' mission statements (MSs) and Korean Doctor's Role (KDR) domains, considering school characteristics.: Methods: We analyzed the South Korean medical school's MS characteristics ...

    Abstract Purpose: This study assessed the alignment between Korean medical schools' mission statements (MSs) and Korean Doctor's Role (KDR) domains, considering school characteristics.
    Methods: We analyzed the South Korean medical school's MS characteristics using a mixed-methods approach. Quantitative analysis preprocessed MS text data to identify concept words, while qualitative content analysis categorized information into predefined KDR domains and extracted themes from other parts.
    Results: At the KDR domain level, "social accountability" was the most frequent, followed by "education and research" and "patient care," while "professionalism" had the least frequency. At the competency level, the most frequent domains were "involvement in public and global health initiatives," while "self-regulation based on professional leadership" and "professionalism and self-management" were not present.
    Conclusion: The study found that the majority of MSs had a homogeneous pattern and included traditional themes. Medical schools should evaluate and incorporate missing elements in their MSs to reflect the institution's own purpose and current societal needs.
    MeSH term(s) Humans ; Schools, Medical ; Education, Medical ; Professionalism ; Republic of Korea
    Language English
    Publishing date 2024-02-28
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2846769-3
    ISSN 2005-7288 ; 2005-2367 ; 2005-727X ; 1225-8067
    ISSN (online) 2005-7288 ; 2005-2367
    ISSN 2005-727X ; 1225-8067
    DOI 10.3946/kjme.2024.287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Passivity, task segmentation, and relational capital: a study of interpersonal relationship formation among freshman medical students in team-based activities.

    Lee, Hyo Jeong / Kim, Do-Hwan / Kang, Ye Ji

    Korean journal of medical education

    2023  Volume 35, Issue 3, Page(s) 223–233

    Abstract: Purpose: Team-based learning in medical education facilitates the formation of interpersonal relationships, enhances academic achievement, and establishes future clinical connections. Despite medical schools' distinct educational environments and ... ...

    Abstract Purpose: Team-based learning in medical education facilitates the formation of interpersonal relationships, enhances academic achievement, and establishes future clinical connections. Despite medical schools' distinct educational environments and curricula, research investigating students' learning and behavioral characteristics within this context remains limited. This study aimed to investigate the specific characteristics of interpersonal relationship formation among freshmen medical students in team-based learning activities.
    Methods: Focus group interviews were conducted with 11 students who participated in a team-based class held during the first semester of the premedical year.
    Results: Medical students passively expressed their thoughts and feelings, such as active sympathy for the team's opinions and self-censorship of SNS (social networking service) conversations. When performing team activities, students were excessively conscious of others and focused on evenly dividing their work, minimizing their opinions, and fulfilling their share to prevent potential interpersonal conflicts. Interpersonal activities were only superficial, as students intentionally maintained a certain distance from team members or used team activities as an opportunity to accumulate relational capital.
    Conclusion: The results of this study are expected to provide a useful basis for designing and conducting team activity classes to enhance interpersonal relationship formation.
    MeSH term(s) Humans ; Students, Medical ; Interpersonal Relations ; Emotions ; Academic Success ; Communication
    Language English
    Publishing date 2023-08-31
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2846769-3
    ISSN 2005-7288 ; 2005-2367 ; 2005-727X ; 1225-8067
    ISSN (online) 2005-7288 ; 2005-2367
    ISSN 2005-727X ; 1225-8067
    DOI 10.3946/kjme.2023.261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Nipple Schwannoma: A Case Report and Literature Review on Nipple Mass.

    Kang, Ye Ju / Woo, Ok Hee / Kim, Aeree

    Journal of breast cancer

    2023  Volume 27, Issue 1, Page(s) 72–77

    Abstract: Schwannomas are slow-growing benign tumors originating from the Schwann cells of the peripheral nerve sheaths. Herein, we report the first documented case of a schwannoma presenting as a painful nipple mass in a 32-year-old woman. This mass initially ... ...

    Abstract Schwannomas are slow-growing benign tumors originating from the Schwann cells of the peripheral nerve sheaths. Herein, we report the first documented case of a schwannoma presenting as a painful nipple mass in a 32-year-old woman. This mass initially developed six years ago following a period of breastfeeding. Breast magnetic resonance imaging (MRI) scans revealed an iso-intense mass, with an approximate size of 2.2 cm, on a T1-weighted image with internal cystic changes. The mass exhibited heterogeneously delayed enhancement and restricted diffusion. Surgical excision was performed, and the diagnosis of cutaneous plexiform nipple schwannoma was confirmed histopathologically. A literature review revealed that the MRI findings of the nipple mass in our case were consistent with the common features of a schwannoma.
    Language English
    Publishing date 2023-11-17
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 2559753-X
    ISSN 2092-9900 ; 1738-6756
    ISSN (online) 2092-9900
    ISSN 1738-6756
    DOI 10.4048/jbc.2023.0119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pre-clerkship students' perception and learning behavior of online classes during coronavirus disease 2019 pandemic.

    Kang, Ye Ji / Kim, Do-Hwan

    Korean journal of medical education

    2021  Volume 33, Issue 2, Page(s) 125–131

    Abstract: Purpose: This study aims to analyze pre-clerkship medical students' learning strategies and perceptions in online classes during the coronavirus disease 2019 pandemic.: Methods: To develop the survey items, 20 pre-clerkship students were interviewed ... ...

    Abstract Purpose: This study aims to analyze pre-clerkship medical students' learning strategies and perceptions in online classes during the coronavirus disease 2019 pandemic.
    Methods: To develop the survey items, 20 pre-clerkship students were interviewed about their learning experiences in the first semester of 2020. A total of 425 pre-clerkship students have participated in the survey, which comprised four parts (general experience, learning strategies, important features, and overall satisfaction).
    Results: Before classes began, students generally had "neutral expectations" about online classes (2.90 out of 5). At the end of the semester, overall satisfaction with the curriculum was moderate (3.04 out of 5). Premedical students reported lower scores in "daily study hours" and "regular lifestyle" and higher scores in "experience of playing recorded lectures solely for an attendance check" (p<0.001). In addition, first-year premedical students not only showed significantly lower utilization of learning strategies compared to other grades (p<0.001).
    Conclusion: Although pre-clerkship students mostly shared similar perceptions and behaviors in their learning regardless of grade level, some characteristics were either more prominent in premedical students on the whole or limited to first-year premedical students.
    MeSH term(s) Adolescent ; Adult ; Attitude ; COVID-19 ; Clinical Clerkship ; Curriculum ; Education, Distance ; Education, Medical, Undergraduate/methods ; Female ; Humans ; Learning ; Male ; Pandemics ; Perception ; Personal Satisfaction ; SARS-CoV-2 ; Students, Medical ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2021-05-26
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2846769-3
    ISSN 2005-7288 ; 2005-2367 ; 2005-727X ; 1225-8067
    ISSN (online) 2005-7288 ; 2005-2367
    ISSN 2005-727X ; 1225-8067
    DOI 10.3946/kjme.2021.194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The hidden hurdles of clinical clerkship: unraveling the types and distribution of professionalism dilemmas among South Korean medical students.

    Kang, Ye Ji / Lin, Yanyan / Rho, Jaehee / Ihm, Jungjoon / Kim, Do-Hwan

    BMC medical education

    2024  Volume 24, Issue 1, Page(s) 150

    Abstract: Background: To improve the medical professionalism of medical students, it is essential to understand the dilemmas they face in various situations. This study explored the types and distribution of dilemmas Korean medical students encounter during their ...

    Abstract Background: To improve the medical professionalism of medical students, it is essential to understand the dilemmas they face in various situations. This study explored the types and distribution of dilemmas Korean medical students encounter during their clinical clerkships. It then compared these with previous dilemma frameworks and identified the types and distribution of "complexity dilemmas," wherein two dilemma themes emerge in a single clinical situation.
    Methods: The researchers organized and recorded a group discussion with 106 third-year medical students who had completed their clinical clerkships. These students participated in the discussion as part of an assignment, focusing on the dilemmas they encountered during their clerkships. For data analysis and visualization, the researchers employed the MAXQDA software program and utilized the template analysis method, a qualitative research methodology.
    Results: A total of seven dilemma themes and sixteen sub-themes were identified. The identity-related dilemma concerning student-doctors had the highest frequency. The themes "mismatch" and "Nun-chi" emerged as new additions not found in previous dilemma frameworks. The complexity dilemmas appeared in the sequence of "identity-dignity," "identity-abuse," and "identity-consent".
    Conclusions: To navigate the unique dilemmas present within South Korea's clinical culture, several key issues need consideration: elevating the role of student-doctors, balancing the primary emphasis of educational hospitals on delivering medical services, and understanding interpersonal strategies, such as "Nun-chi".
    MeSH term(s) Humans ; Professionalism ; Students, Medical ; Clinical Clerkship ; Republic of Korea
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-024-05115-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancer.

    Kang, Ye-Lim / Kim, Jiyoung / Kwak, Su-Bin / Kim, Yi-Sook / Huh, June / Park, Jong-Wan

    Experimental & molecular medicine

    2024  Volume 56, Issue 1, Page(s) 220–234

    Abstract: Diabetes might be associated with increased cancer risk, with several studies reporting hyperglycemia as a primary oncogenic stimulant. Since glucose metabolism is linked to numerous metabolic pathways, it is difficult to specify the mechanisms ... ...

    Abstract Diabetes might be associated with increased cancer risk, with several studies reporting hyperglycemia as a primary oncogenic stimulant. Since glucose metabolism is linked to numerous metabolic pathways, it is difficult to specify the mechanisms underlying hyperglycemia-induced cancer progression. Here, we focused on the polyol pathway, which is dramatically activated under hyperglycemia and causes diabetic complications. We investigated whether polyol pathway-derived fructose facilitates hyperglycemia-induced gastric cancer metastasis. We performed bioinformatics analysis of gastric cancer datasets and immunohistochemical analyses of gastric cancer specimens, followed by transcriptomic and proteomic analyses to evaluate phenotypic changes in gastric cancer cells. Consequently, we found a clinical association between the polyol pathway and gastric cancer progression. In gastric cancer cell lines, hyperglycemia enhanced cell migration and invasion, cytoskeletal rearrangement, and epithelial-mesenchymal transition (EMT). The hyperglycemia-induced acquisition of metastatic potential was mediated by increased fructose derived from the polyol pathway, which stimulated the nuclear ketohexokinase-A (KHK-A) signaling pathway, thereby inducing EMT by repressing the CDH1 gene. In two different xenograft models of cancer metastasis, gastric cancers overexpressing AKR1B1 were found to be highly metastatic in diabetic mice, but these effects of AKR1B1 were attenuated by KHK-A knockdown. In conclusion, hyperglycemia induces fructose formation through the polyol pathway, which in turn stimulates the KHK-A signaling pathway, driving gastric cancer metastasis by inducing EMT. Thus, the polyol and KHK-A signaling pathways could be potential therapeutic targets to decrease the metastatic risk in gastric cancer patients with diabetes.
    MeSH term(s) Humans ; Animals ; Mice ; Stomach Neoplasms/genetics ; Stomach Neoplasms/metabolism ; Diabetes Mellitus, Experimental ; Proteomics ; Signal Transduction ; Hyperglycemia/complications ; Fructokinases/genetics ; Fructokinases/metabolism ; Fructose/metabolism ; Epithelial-Mesenchymal Transition/genetics ; Cell Movement/genetics ; Cell Line, Tumor ; Aldehyde Reductase/genetics ; Aldehyde Reductase/metabolism ; Aldehyde Reductase/pharmacology ; Polymers
    Chemical Substances polyol ; Fructokinases (EC 2.7.1.-) ; Fructose (30237-26-4) ; AKR1B1 protein, human (EC 1.1.1.21) ; Aldehyde Reductase (EC 1.1.1.21) ; Polymers
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1328915-9
    ISSN 2092-6413 ; 1226-3613 ; 0378-8512
    ISSN (online) 2092-6413
    ISSN 1226-3613 ; 0378-8512
    DOI 10.1038/s12276-023-01153-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The emerging role of USP29 in cancer and other diseases.

    Zhang, Ru / Cai, Zeqiong / Ren, Doudou / Kang, Ye / Zhang, Qi / Lu, Xinlan / Tu, Rongfu

    Cell biochemistry and function

    2024  Volume 42, Issue 1, Page(s) e3928

    Abstract: Reversible protein ubiquitination is a key process for maintaining cellular homeostasis. Deubiquitinases, which can cleave ubiquitin from substrate proteins, have been reported to be deeply involved in disease progression ranging from oncology to ... ...

    Abstract Reversible protein ubiquitination is a key process for maintaining cellular homeostasis. Deubiquitinases, which can cleave ubiquitin from substrate proteins, have been reported to be deeply involved in disease progression ranging from oncology to neurological diseases. The human genome encodes approximately 100 deubiquitinases, most of which are poorly characterized. One of the well-characterized deubiquitases is ubiquitin-specific protease 29 (USP29), which is often upregulated in pathological tissues and plays important roles in the progression of different diseases. Moreover, several studies have shown that deletion of Usp29 in mice does not cause visible growth and developmental defects, indicating that USP29 may be an ideal therapeutic target. In this review, we provide a comprehensive summary of the important roles and regulatory mechanisms of USP29 in cancer and other diseases, which may help us better understand its biological functions and improve future studies to construct suitable USP29-targeted therapy systems.
    MeSH term(s) Humans ; Animals ; Mice ; Neoplasms/genetics ; Genome, Human ; Ubiquitin ; Ubiquitination ; Deubiquitinating Enzymes ; Ubiquitin-Specific Proteases/genetics
    Chemical Substances Ubiquitin ; Deubiquitinating Enzymes (EC 3.4.19.12) ; USP29 protein, human (EC 3.4.19.12) ; Ubiquitin-Specific Proteases (EC 3.4.19.12) ; Usp29 protein, mouse (EC 3.4.19.12)
    Language English
    Publishing date 2024-01-25
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 283643-9
    ISSN 1099-0844 ; 0263-6484
    ISSN (online) 1099-0844
    ISSN 0263-6484
    DOI 10.1002/cbf.3928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Gene Profile and Clinical Significance of Concomitant Mutations in CN-AML Patients with

    Zhu, Jing / Kang, Ye-Fang / Gao, Yuan / Wang, Hong-Wei / Hao, Zhuang-Hui

    Zhongguo shi yan xue ye xue za zhi

    2024  Volume 32, Issue 2, Page(s) 335–341

    Abstract: Objective: To analyze the occurrence of concomitant gene mutations in cytogenetically normal acute myeloid leukemia (CN-AML) patients with : Methods: 151 newly diagnosed patients with CN-AML in the Second Hospital of Shanxi Medical University from ... ...

    Abstract Objective: To analyze the occurrence of concomitant gene mutations in cytogenetically normal acute myeloid leukemia (CN-AML) patients with
    Methods: 151 newly diagnosed patients with CN-AML in the Second Hospital of Shanxi Medical University from June 2013 to June 2020 were analyzed retrospectively. 34 common genetic mutations associated with hematologic malignancies were detected by next-generation sequencing technology. The occurrence of concomitant gene mutations in patients with
    Results: In 151 patients with CN-AML, 55 (36.42%) were positive for
    Conclusion: CN-AML patients with
    MeSH term(s) Humans ; Leukemia, Myeloid, Acute/genetics ; Mutation ; CCAAT-Enhancer-Binding Proteins/genetics ; Retrospective Studies ; Prognosis ; Dioxygenases ; GATA2 Transcription Factor/genetics ; DNA-Binding Proteins/genetics ; Proto-Oncogene Proteins/genetics ; WT1 Proteins/genetics ; Male ; Female ; Clinical Relevance
    Chemical Substances CCAAT-Enhancer-Binding Proteins ; CEBPA protein, human ; TET2 protein, human (EC 1.13.11.-) ; Dioxygenases (EC 1.13.11.-) ; GATA2 Transcription Factor ; GATA2 protein, human ; DNA-Binding Proteins ; Proto-Oncogene Proteins ; WT1 Proteins ; WT1 protein, human
    Language Chinese
    Publishing date 2024-04-25
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2404306-0
    ISSN 1009-2137
    ISSN 1009-2137
    DOI 10.19746/j.cnki.issn.1009-2137.2024.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Prevalence of cancer-related fatigue based on severity: a systematic review and meta-analysis.

    Kang, Ye-Eun / Yoon, Ji-Hae / Park, Na-Hyun / Ahn, Yo-Chan / Lee, Eun-Jung / Son, Chang-Gue

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 12815

    Abstract: Cancer-related fatigue (CRF) affects therapeutic compliance and clinical outcomes including recurrence and mortality. This study aimed to comprehensively and comparatively assess the severity-based prevalence of CRF. From two public databases (PubMed and ...

    Abstract Cancer-related fatigue (CRF) affects therapeutic compliance and clinical outcomes including recurrence and mortality. This study aimed to comprehensively and comparatively assess the severity-based prevalence of CRF. From two public databases (PubMed and Cochrane Library), we extracted data containing information on both prevalence and severity of fatigue in cancer patients through December 2021. We conducted a meta-analysis to produce point estimates using random effects models. Subgroup analyses were used to assess the prevalence and severity by the organ/system tumor development, treatment phase, therapeutic type, sex and assessment method. A total of 151 data (57 studies, 34,310 participants, 11,805 males and 22,505 females) were selected, which indicated 43.0% (95% CI 39.2-47.2) of fatigue prevalence. The total CRF prevalence including 'mild' level of fatigue was 70.7% (95% CI 60.6-83.3 from 37 data). The prevalence of 'severe' fatigue significantly varied by organ/system types of cancer origin (highest in brain tumors 39.7% vs. lowest in gynecologic tumors 3.9%) and treatment phase likely 15.9% (95% CI 8.1-31.3) before treatment, 33.8% (95% CI 27.7-41.2) ongoing treatment, and 24.1% (95% CI 18.6-31.2) after treatment. Chemotherapy (33.1%) induced approximately 1.5-fold higher prevalence for 'severe' CRF than surgery (22.0%) and radiotherapy (24.2%). The self-reported data for 'severe' CRF was 20-fold higher than those assessed by physicians (23.6% vs. 1.6%). Female patients exhibited a 1.4-fold higher prevalence of 'severe' fatigue compared to males. The present data showed quantitative feature of the prevalence and severity of CRF based on the cancer- or treatment-related factors, sex, and perspective of patient versus physician. In the context of the medical impact of CRF, our results provide a comparative reference to oncologists or health care providers making patient-specific decision.
    MeSH term(s) Male ; Humans ; Female ; Prevalence ; Neoplasms/complications ; Neoplasms/epidemiology ; Neoplasms/therapy ; Fatigue/epidemiology ; Fatigue/etiology ; Fatigue/drug therapy ; Genital Neoplasms, Female ; Self Report ; Quality of Life
    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-39046-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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