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  1. AU="Kansakar, Prerana"
  2. AU="McCullagh, Elizabeth A"
  3. AU="Pereira, Ivanio Alves"
  4. AU="Singh, Rupinder"
  5. AU="Leung, Cheuk Lun"
  6. AU=Berman Claudia G
  7. AU=Chang Wen Xiu
  8. AU=Chen Jianchun
  9. AU="Zhou, Long" AU="Zhou, Long"
  10. AU=Bauer Michael AU=Bauer Michael
  11. AU=Clapp Benjamin
  12. AU="Makarenko, V"
  13. AU="Stahl, Anna"
  14. AU="Wa, Qingbo"
  15. AU="Annette T. Byrne"
  16. AU="Godwin Oligbu"

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  1. Artikel ; Online: Vision loss associated with orbital surgery - a major review.

    Kansakar, Prerana / Sundar, Gangadhara

    Orbit (Amsterdam, Netherlands)

    2019  Band 39, Heft 3, Seite(n) 197–208

    Abstract: ... ...

    Abstract Purpose
    Mesh-Begriff(e) Blindness/etiology ; Decompression, Surgical ; Humans ; Ophthalmologic Surgical Procedures ; Orbital Diseases/surgery ; Postoperative Complications/etiology ; Reconstructive Surgical Procedures ; Risk Factors
    Sprache Englisch
    Erscheinungsdatum 2019-10-01
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review ; Video-Audio Media
    ZDB-ID 603157-2
    ISSN 1744-5108 ; 0167-6830
    ISSN (online) 1744-5108
    ISSN 0167-6830
    DOI 10.1080/01676830.2019.1658790
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Risk Factors Associated with Diabetic Ketoacidosis at the Onset of Type 1 Diabetes Mellitus.

    Kansakar, Prerana / Shrestha, Shrijana / Paudyal, Buddhi Prasad / Prajapati, Alisha / Shrestha, Narottam

    Journal of Nepal Health Research Council

    2022  Band 20, Heft 1, Seite(n) 79–83

    Abstract: Background: There are various factors which increase the risk of diabetic ketoacidosis at the onset of type 1 diabetes mellitus. There have not been any such studies in our setting. This study was done to find the prevalence and risk factors associated ... ...

    Abstract Background: There are various factors which increase the risk of diabetic ketoacidosis at the onset of type 1 diabetes mellitus. There have not been any such studies in our setting. This study was done to find the prevalence and risk factors associated with the development of diabetic ketoacidosis at onset of type 1 diabetes mellitus.
    Methods: Children and young adults with type 1 diabetes mellitus being treated at Patan hospital were approached and after obtaining an informed consent, all the patient information on various risk factors for diabetic ketoacidosis were collected in a pre-developed proforma. Data was entered in Microsoft Excel and analysis was done using statistical package for the social sciences-16. Ethical approval was taken from Institutional Review Committee- Patan Academy of Health Sciences.
    Results: Out of 99 patients with type 1 diabetes enrolled in the study, 52.5% presented in diabetic ketoacidosis at the onset. The duration of symptoms was significantly less in patient presenting with diabetic ketoacidosis than without diabetic ketoacidosis (6.45±7.57 vs 9.13±10.12, p=0.04). There was no significant difference in the mean age, mean glycosylated hemoglobin, mean body mass index, gender, parents' literacy and medical consultations prior to diagnosis.
    Conclusions: More than half of the patients with type 1 diabetes presented in diabetic ketoacidosis. The shorter duration of symptoms prior to presentation was the only significant factor leading to presentation as diabetic ketoacidosis.
    Mesh-Begriff(e) Child ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/diagnosis ; Diabetes Mellitus, Type 1/epidemiology ; Diabetic Ketoacidosis/complications ; Diabetic Ketoacidosis/etiology ; Glycated Hemoglobin A/analysis ; Humans ; Nepal ; Risk Factors ; Young Adult
    Chemische Substanzen Glycated Hemoglobin A
    Sprache Englisch
    Erscheinungsdatum 2022-06-02
    Erscheinungsland Nepal
    Dokumenttyp Journal Article
    ZDB-ID 2551251-1
    ISSN 1999-6217 ; 1999-6217
    ISSN (online) 1999-6217
    ISSN 1999-6217
    DOI 10.33314/jnhrc.v20i01.3841
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Congenital Tracheoesophageal Fistula in Very Low Birth Weight Preterm Neonate with an Oligohydramnios as a Rare Presentation: A Case Report.

    Maharjan, Anu / Sharma, Amit Kumar / Kansakar, Prerana / K C, Samyukta / Singh, Yogendra

    JNMA; journal of the Nepal Medical Association

    2020  Band 58, Heft 232, Seite(n) 1075–1079

    Abstract: Tracheoesophageal fistula is a challenging anomaly with a rare prevalence with symptoms mainly respiratory, sometimes digestive. We present a rare case of oesophageal atresia with distal Tracheoesophageal fistula in a female child whose mother presented ... ...

    Abstract Tracheoesophageal fistula is a challenging anomaly with a rare prevalence with symptoms mainly respiratory, sometimes digestive. We present a rare case of oesophageal atresia with distal Tracheoesophageal fistula in a female child whose mother presented with severe oligohydramnios on ultrasonography with intrauterine growth retardation before cesarean section. After the birth of preterm and very low birth weight neonate, we initially diagnosed as respiratory distress syndrome with a club foot. However, we diagnosed oesophageal atresia with distal Tracheoesophageal fistula on the 2nd day as nasogastric tube insertion was failed beyond 10cm and confirmed by X-ray with a rubber catheter. Right thoracotomy with ligation of the fistula with end to end anastomosis was performed successfully without complications. Breastfeeding initiated and the child discharged after she started gaining weight. Early post-operation complication (anastomotic stricture) was noticed after 2 weeks; however, corrected with endoscopic balloon dilatation. Currently, the child is healthy weighing 10kgs at 18 months of age.
    Mesh-Begriff(e) Cesarean Section/adverse effects ; Child ; Esophageal Atresia/complications ; Esophageal Atresia/diagnosis ; Esophageal Atresia/surgery ; Female ; Humans ; Infant, Newborn ; Infant, Very Low Birth Weight ; Oligohydramnios ; Pregnancy ; Tracheoesophageal Fistula/diagnosis ; Tracheoesophageal Fistula/surgery
    Sprache Englisch
    Erscheinungsdatum 2020-12-31
    Erscheinungsland Nepal
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 2209910-4
    ISSN 1815-672X ; 0028-2715
    ISSN (online) 1815-672X
    ISSN 0028-2715
    DOI 10.31729/jnma.5207
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Clinical Profiles of Neonates Born to COVID-19 Positive Mothers in a Tertiary Care Centre: A Descriptive Cross-sectional Study.

    Sharma Chalise, Shiva Prasad / Kumar Mishra, Santosh / Sharma Chalise, Bimal / Rai, Punam / Paudel, Subash / Kansakar, Prerana / Raj Ojha, Anil

    JNMA; journal of the Nepal Medical Association

    2021  Band 59, Heft 239, Seite(n) 667–671

    Abstract: Introduction: Nepal is one of the countries which has been hit hard by the COVID-19 pandemic and has resulted in high morbidity and mortality across all age groups including neonates. There has been a paucity of studies regarding maternal to neonatal ... ...

    Abstract Introduction: Nepal is one of the countries which has been hit hard by the COVID-19 pandemic and has resulted in high morbidity and mortality across all age groups including neonates. There has been a paucity of studies regarding maternal to neonatal COVID-19 transmission and the published studies also have a poor sample size to reach any definite conclusion. Hence this study was carried out to see the clinical profiles of neonates born to COVID-19 mothers.
    Methods: It was a descriptive cross-sectional study. The study was conducted at a tertiary care centre over the period of one year from April 2020 to March 2021 after taking ethical clearance from the Institutional Review Committee with reference number drs2105211526. Convenient sampling was done. All neonates born to COVID-19 positive mothers who were diagnosed by a real-time polymerase chain reaction of the nasopharyngeal swab during the time of delivery were included in the study. Data analysis was done using Statistical Package for Social Sciences 20 using appropriate tools.
    Results: A total of 105 babies born to COVID-19 positive mothers who were tested for COVID-19 infection were included in the study. Ten (9.5%) (3.89-15.10 at 95% Confidence Interval) of neonates born to COVID-19 positive mothers were positive for the COVID-19 virus. All the neonates born to COVID-19 positive mothers were discharged home except one case who had other comorbidities. Fever was present in four (40%) of COVID-19 positive neonates.
    Conclusions: There is a possibility of vertical transmission of coronavirus in neonates although the outcome is favourable.
    Mesh-Begriff(e) COVID-19 ; Cross-Sectional Studies ; Female ; Humans ; Infant, Newborn ; Mothers ; Pandemics ; Pregnancy ; Pregnancy Complications, Infectious ; SARS-CoV-2 ; Tertiary Care Centers
    Sprache Englisch
    Erscheinungsdatum 2021-07-30
    Erscheinungsland Nepal
    Dokumenttyp Journal Article
    ZDB-ID 2209910-4
    ISSN 1815-672X ; 0028-2715
    ISSN (online) 1815-672X
    ISSN 0028-2715
    DOI 10.31729/jnma.6808
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Newborn Screening for Selected Disorders in Nepal: A Pilot Study.

    Sharma Pandey, Arti / Joshi, Suchita / Rajbhandari, Rateena / Kansakar, Prerana / Dhakal, Sadichhya / Fingerhut, Ralph

    International journal of neonatal screening

    2019  Band 5, Heft 2, Seite(n) 18

    Abstract: The prevalence of metabolic disorders in Nepal is yet unknown, although many case reports occur in literature. Heel-prick blood samples from newborns were collected on Dried Blood Spot (DBS) collection cards and tested through Tandem Mass Spectroscopy ... ...

    Abstract The prevalence of metabolic disorders in Nepal is yet unknown, although many case reports occur in literature. Heel-prick blood samples from newborns were collected on Dried Blood Spot (DBS) collection cards and tested through Tandem Mass Spectroscopy and fluorescence assays for disorders included in the Swiss neonatal screening program; two cases of hypothyroidism and one case of cystic fibrosis were identified. Thyroid stimulating hormone (TSH), immuoreactive trypsinogen (IRT), hydroxyprogesterone (OHP), tyrosine (Tyr), and octanoylcarnitine (C8) showed significant differences with gestation age. Most of the parameters were positively correlated with each other except galactose, galactose 1 phosphate uridyl transferase (GALT), and biotinidase. First and ninety-ninth percentiles in the Nepalese newborns were found to be different when compared with the Swiss newborns. Congenital hypothyroidism and cystic fibrosis are candidates to be considered for a newborn screening program in Nepal. Differences between the Nepalese and Swiss newborns in parametric values that change with gestation age can be attributed to a higher survival rate of pre-term babies in Switzerland. Others could be explained in part by early and exclusive breastfeeding in Nepalese newborns.
    Sprache Englisch
    Erscheinungsdatum 2019-04-10
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 2409-515X
    ISSN (online) 2409-515X
    DOI 10.3390/ijns5020018
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Anterior lens capsule rupture following minor blunt trauma with a past history of minimal change glomerulopathy.

    Lau, Stephen V / Kansakar, Prerana / Limbu, Ben

    Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH

    2014  Band 6, Heft 2, Seite(n) 230–233

    Abstract: Introduction: Few cases have been reported describing anterior lens capsule ruptures secondary to blunt trauma.: Case: We present an unusual case of anterior lens capsule ruptures following minor trauma from a human elbow with a two-year history of ... ...

    Abstract Introduction: Few cases have been reported describing anterior lens capsule ruptures secondary to blunt trauma.
    Case: We present an unusual case of anterior lens capsule ruptures following minor trauma from a human elbow with a two-year history of minimal-change glomerulopathy in a 17-year-old male. In addition to having bilateral posterior subcapsular cataracts, he developed an anterior subcapsular cataract underlying the anterior lens rupture in the right eye. He was managed conservatively.
    Observations: The current case differs from those of the existing literature in terms of the characteristics of the physical insult and the eye on presentation. We suggest there could be a predisposing anterior capsule weakness secondary to the minimal-change glomerulopathy or the associated drug therapy, but there needs to be more evidence to confirm or refute our claim.
    Conclusions: Anterior lens capsule may rupture following minor trauma on a background of minimal-change glomerulopathy.
    Mesh-Begriff(e) Adolescent ; Anterior Eye Segment/injuries ; Eye Injuries/complications ; Eye Injuries/diagnosis ; Humans ; Lens Capsule, Crystalline/injuries ; Male ; Nephrosis, Lipoid/complications ; Rupture ; Wounds, Nonpenetrating/complications ; Wounds, Nonpenetrating/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2014-07
    Erscheinungsland Nepal
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 2596436-7
    ISSN 2091-0320 ; 2072-6805
    ISSN (online) 2091-0320
    ISSN 2072-6805
    DOI 10.3126/nepjoph.v6i2.11714
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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