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  1. Article ; Online: Diverse Farming Systems and their Impact on Macro and Microelement Content of Vegetables & Crops.

    Rani, Madhu / Kapoor, Sonia

    Recent advances in food, nutrition & agriculture

    2024  

    Abstract: Background: The present study investigates the effect of conventional and organic farming systems on the nutritional profile of crops. Different crops, namely -millet, sorghum, sesame, mustard, fenugreek, berseem, pea, potato, and onion were cultivated ... ...

    Abstract Background: The present study investigates the effect of conventional and organic farming systems on the nutritional profile of crops. Different crops, namely -millet, sorghum, sesame, mustard, fenugreek, berseem, pea, potato, and onion were cultivated through conventional agriculture in which chemical fertilizers like urea, DAP (Diammonium Phosphate) and pesticides were used and organic farming in which organic fertilizers like seaweed and vermicompost were used.
    Objective: The experimental study was done on a field in north India from 2019 to 2021 in six different seasons, and the nutrient profile of the crops with respect to macroelements (S, K, Na, P, Ca, Mg) and microelements (B, Cu, Fe, Mn, Zn, Al) was compared.
    Methods: Macro and microelements were analyzed by Element analyzer and ICP-OES in both types of farming systems. The content of macro, as well as microelements, was found to be significantly higher in all the organically produced crops as compared to the conventionally grown crops.
    Results: Significant differences were observed in the macroelement content of organic onion (P900 mg/kg, K-2000mg/kg) and organic pea (K 2250 mg/kg) as compared to the content of conventionally grown onion (P-756 mg/kg, K- 1550 mg/kg) and pea (K-2000 mg/kg). Similarly, microelement content in the organic sesame (Fe - 3.12 mg/kg), organic millet (Fe- 2.19 mg/kg), and organic potato (Zn-200 mg/kg) was higher as compared to conventionally grown sesame (Fe 2.05 mg/kg), millet (Fe- 1.56 mg/kg) and potato (Zn 167 mg/kg).
    Conclusion: This investigation concludes that crops with optimum nutritional content can be produced through organic farming with minimum input and maximum production.
    Language English
    Publishing date 2024-01-26
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 2772-5758
    ISSN (online) 2772-5758
    DOI 10.2174/012772574X282571231227054442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Engaging nurses in developing generative artificial intelligence-based technologies can enhance their work motivation, engagement and satisfaction.

    Singh, Shaminder / Kapoor, Sumeeta

    Evidence-based nursing

    2024  

    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425988-6
    ISSN 1468-9618 ; 1367-6539
    ISSN (online) 1468-9618
    ISSN 1367-6539
    DOI 10.1136/ebnurs-2023-103783
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5184: Show issues Location:
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  3. Article ; Online: Managing patients' pain while preserving sleep quality and efficiency.

    Singh, Shaminder / Kapoor, Sumeeta

    Evidence-based nursing

    2024  

    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425988-6
    ISSN 1468-9618 ; 1367-6539
    ISSN (online) 1468-9618
    ISSN 1367-6539
    DOI 10.1136/ebnurs-2023-103704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5184: Show issues Location:
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  4. Book: Insight into influenza viruses of animals and humans

    Kapoor, Sanjay / Dhama, Kuldeep

    2014  

    Author's details Sanjay Kapoor ; Kuldeep Dhama
    Keywords Influenza viruses ; Public health ; Animal health
    Subject code 616.203019
    Language English
    Size XIII, 222 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Germany
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018262558
    ISBN 978-3-319-05511-4 ; 9783319055121 ; 3-319-05511-9 ; 3319055127
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2014 A 1958 available for loan (reading room) Lesesaal EG

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  5. Article: IS TRAUMA RESUSCITATION SAME AS CLASSICAL CARDIAC RESUSCITATION?: Authors' Reply.

    Kapoor, S

    Medical journal, Armed Forces India

    2017  Volume 54, Issue 1, Page(s) 86

    Language English
    Publishing date 2017-06-26
    Publishing country India
    Document type Journal Article
    ZDB-ID 196342-9
    ISSN 0377-1237
    ISSN 0377-1237
    DOI 10.1016/S0377-1237(17)30429-X
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  6. Article ; Online: A unique and often overlooked cause of Blepharophimosis: "Whistling face syndrome".

    Kapoor, S

    Orbit (Amsterdam, Netherlands)

    2016  Volume 35, Issue 6, Page(s) 350

    MeSH term(s) Blepharophimosis/diagnosis ; Blepharophimosis/etiology ; Craniofacial Dysostosis/complications ; Craniofacial Dysostosis/diagnosis ; Humans
    Language English
    Publishing date 2016-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 603157-2
    ISSN 1744-5108 ; 0167-6830
    ISSN (online) 1744-5108
    ISSN 0167-6830
    DOI 10.1080/01676830.2016.1193540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1735: Show issues Location:
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  7. Article ; Online: "Immune reconstitution inflammatory syndrome"-a rare complication of Whipple's disease.

    Kapoor, S

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

    2016  Volume 35, Issue 6, Page(s) 1045–1046

    MeSH term(s) Disease Management ; Humans ; Immune Reconstitution Inflammatory Syndrome/diagnosis ; Immune Reconstitution Inflammatory Syndrome/etiology ; Immune Reconstitution Inflammatory Syndrome/therapy ; Whipple Disease/complications
    Language English
    Publishing date 2016-06
    Publishing country Germany
    Document type Letter
    ZDB-ID 603155-9
    ISSN 1435-4373 ; 0934-9723 ; 0722-2211
    ISSN (online) 1435-4373
    ISSN 0934-9723 ; 0722-2211
    DOI 10.1007/s10096-016-2626-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 1732: Show issues Location:
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  8. Article ; Online: Phloretin suppresses intestinal inflammation and maintained epithelial tight junction integrity by modulating cytokines secretion in in vitro model of gut inflammation.

    Kapoor, Smita / Padwad, Yogendra S

    Cellular immunology

    2023  Volume 391-392, Page(s) 104754

    Abstract: Ulcerative colitis is a type of inflammatory bowel disease which in long run can lead to colorectal cancer (CRC). Chronic inflammation can be a key factor for the occurrence of CRC thus mitigating an inflammation can be a preventive strategy for the ... ...

    Abstract Ulcerative colitis is a type of inflammatory bowel disease which in long run can lead to colorectal cancer (CRC). Chronic inflammation can be a key factor for the occurrence of CRC thus mitigating an inflammation can be a preventive strategy for the occurrence of CRC. In this study we have explored the anti-inflammatory potential of phloretin, in in vitro gut inflammation model, developed by co-culture of Caco2 (intestinal epithelial) cells and RAW264.7 macrophages (immune cells). Phloretin is a dihydrochalcone present in apple, pear and strawberries. An anti-inflammatory effect of phloretin in reducing LPS induced inflammation and maintenance of transepithelial electric resistance (TEER) in Caco2 cells was examined. Paracellular permeability assay was performed using Lucifer yellow dye to evaluate the effect of phloretin in inhibiting gut leakiness caused by inflammatory mediators secreted by activated macrophages. Phloretin attenuated LPS induced nitric oxide levels, oxidative stress, depolarization of mitochondrial membrane potential in Caco2 cells as evidenced by reduction in reactive oxygen species (ROS), and enhancement of MMP, and decrease in inflammatory cytokines IL8, TNFα, IL1β and IL6. It exhibited anti-inflammatory activity by inhibiting the expression of NFκB, iNOS and Cox2. Phloretin maintained the epithelial integrity by regulating the expression of tight junction proteins ZO1, occludin, Claudin1 and JAM. Phloretin reduced LPS induced levels of Cox2 along with the reduction in Src expression which further regulated an expression of tight junction protein occludin. Phloretin in combination to sodium pyruvate exhibited potential anti-inflammatory activity via targeting NFkB signaling. Our findings paved a way to position phloretin as nutraceutical in preventing the occurrence of colitis and culmination of disease into colitis associated colorectal cancer.
    MeSH term(s) Humans ; Occludin/metabolism ; Occludin/pharmacology ; Caco-2 Cells ; Tight Junctions ; Phloretin/pharmacology ; Phloretin/metabolism ; Lipopolysaccharides/pharmacology ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2/pharmacology ; Inflammation/drug therapy ; Inflammation/metabolism ; Cytokines/metabolism ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/metabolism ; NF-kappa B/metabolism ; Intestinal Mucosa/metabolism
    Chemical Substances Occludin ; Phloretin (S5J5OE47MK) ; Lipopolysaccharides ; Cyclooxygenase 2 (EC 1.14.99.1) ; Cytokines ; Anti-Inflammatory Agents ; NF-kappa B
    Language English
    Publishing date 2023-07-24
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80094-6
    ISSN 1090-2163 ; 0008-8749
    ISSN (online) 1090-2163
    ISSN 0008-8749
    DOI 10.1016/j.cellimm.2023.104754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 417: Show issues Location:
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  9. Article ; Online: Biophysical Interaction Landscape of Mycobacterial Mycolic Acids and Phenolic Glycolipids with Host Macrophage Membranes.

    Srivatsav, Aswin T / Kapoor, Shobhna

    ACS applied bio materials

    2023  Volume 6, Issue 12, Page(s) 5555–5562

    Abstract: Lipidic adjuvant formulations consisting of immunomodulatory mycobacterial cell wall lipids interact with host cells following administration. The impact of this cross-talk on the host membrane's structure and function is rarely given enough ... ...

    Abstract Lipidic adjuvant formulations consisting of immunomodulatory mycobacterial cell wall lipids interact with host cells following administration. The impact of this cross-talk on the host membrane's structure and function is rarely given enough consideration but is imperative to rule out nonspecific perturbation underlying the adjuvant. In this work, we investigated changes in the plasma membranes of live mammalian cells after exposure to mycobacterial mycolic acid (MA) and phenolic glycolipids, two strong candidates for lipidic adjuvant therapy. We found that phenolic glycolipid 1 softened the plasma membrane, lowering membrane tension and stiffness, but MA did not significantly change the membrane characteristics. Further, phenolic glycolipid 1 had a fluidizing impact on the host plasma membrane, increasing the fluidity and the abundance of fluid-ordered-disordered coexisting lipid domains. Notably, lipid diffusion was not impacted. Overall, MA and, to a lesser extent, phenolic glycolipid 1, due to minor disruption of host cell membranes, may serve as appropriate lipids in adjuvant formulations.
    MeSH term(s) Animals ; Glycolipids/analysis ; Glycolipids/chemistry ; Glycolipids/metabolism ; Mycolic Acids/analysis ; Mycolic Acids/chemistry ; Mycolic Acids/metabolism ; Cell Membrane/chemistry ; Cell Wall ; Adjuvants, Immunologic ; Macrophages/metabolism ; Mammals/metabolism
    Chemical Substances Glycolipids ; Mycolic Acids ; Adjuvants, Immunologic
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ISSN 2576-6422
    ISSN (online) 2576-6422
    DOI 10.1021/acsabm.3c00748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Leakage and the reproducibility crisis in machine-learning-based science.

    Kapoor, Sayash / Narayanan, Arvind

    Patterns (New York, N.Y.)

    2023  Volume 4, Issue 9, Page(s) 100804

    Abstract: Machine-learning (ML) methods have gained prominence in the quantitative sciences. However, there are many known methodological pitfalls, including data leakage, in ML-based science. We systematically investigate reproducibility issues in ML-based ... ...

    Abstract Machine-learning (ML) methods have gained prominence in the quantitative sciences. However, there are many known methodological pitfalls, including data leakage, in ML-based science. We systematically investigate reproducibility issues in ML-based science. Through a survey of literature in fields that have adopted ML methods, we find 17 fields where leakage has been found, collectively affecting 294 papers and, in some cases, leading to wildly overoptimistic conclusions. Based on our survey, we introduce a detailed taxonomy of eight types of leakage, ranging from textbook errors to open research problems. We propose that researchers test for each type of leakage by filling out model info sheets, which we introduce. Finally, we conduct a reproducibility study of civil war prediction, where complex ML models are believed to vastly outperform traditional statistical models such as logistic regression (LR). When the errors are corrected, complex ML models do not perform substantively better than decades-old LR models.
    Language English
    Publishing date 2023-08-04
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3899
    ISSN (online) 2666-3899
    DOI 10.1016/j.patter.2023.100804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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