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  1. Article ; Online: Edge state behavior in a Su-Schrieffer-Heeger like model with periodically modulated hopping.

    Kar, Satyaki

    Journal of physics. Condensed matter : an Institute of Physics journal

    2023  Volume 36, Issue 6

    Abstract: Su-Schrieffer-Heeger (SSH) model is one of the simplest models to show topological end/edge states and the existence of Majorana fermions. Here we consider a SSH like model both in one and two dimensions where a nearest neighbor hopping features ... ...

    Abstract Su-Schrieffer-Heeger (SSH) model is one of the simplest models to show topological end/edge states and the existence of Majorana fermions. Here we consider a SSH like model both in one and two dimensions where a nearest neighbor hopping features spatially periodic modulations. In the 1D chain, we witness appearance of new in-gap end states apart from a pair of Majorana zero modes (MZMs) when the hopping periodicity go beyond two lattice spacings. The pair of MZMs, that appear in the topological regime, characterize the end modes each existing in either end of the chain. These, however, crossover to both-end end modes for small hopping modulation strength in a finite chain. Contrarily in a 2D SSH model with symmetric hopping that we consider, both non-zero and zero energy topological states appear in a finite square lattice even with a simple staggered hopping, though the zero energy modes disappear in a ribbon configuration. Apart from edge modes, the 2D system also features corner modes as well as modes with satellite peaks distributed non-randomly within the lattice. In both the dimensions, an increase in the periodicity of hopping modulation causes the zero energy Majorana modes to become available for either sign of the modulation. But interestingly with different periodicity for hopping modulations in the two directions, the zero energy modes in a 2D model become rarer and does not appear for all strength and sign of the modulation.
    Language English
    Publishing date 2023-11-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/ad0766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Post COVID-19 Pedal Oedema: An Unusual Residual Feature.

    Sharma, S / Kar, S

    Mymensingh medical journal : MMJ

    2022  Volume 31, Issue 1, Page(s) 234–236

    Abstract: Severe Coronavirus disease 2019 (COVID-19) is a multi-systemic disease which presents with respiratory, gastrointestinal or musculoskeletal symptoms. Patients also display myriad post-COVID19 symptoms which range from myalgia to depression. We present ... ...

    Abstract Severe Coronavirus disease 2019 (COVID-19) is a multi-systemic disease which presents with respiratory, gastrointestinal or musculoskeletal symptoms. Patients also display myriad post-COVID19 symptoms which range from myalgia to depression. We present case series of unusual and unreported post-COVID19 feature in nine cases who had recovered completely but developed pedal oedema which could not be attributed to any other organic cause. These COVID-19 cases were examined in out-patient department for various post-COVID-19 symptoms at tertiary care centers in North India and Bangladesh from July 2020 to February 2021. Ethical clearance was taken and consent obtained from each patient included in this case series.
    MeSH term(s) COVID-19 ; Edema/diagnosis ; Edema/etiology ; Humans ; India ; SARS-CoV-2 ; Tertiary Care Centers
    Language English
    Publishing date 2022-01-09
    Publishing country Bangladesh
    Document type Journal Article
    ZDB-ID 2435083-7
    ISSN 2408-8757 ; 1022-4742
    ISSN (online) 2408-8757
    ISSN 1022-4742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Quantum oscillation and Landau-Zener transition in untilted nodal line semimetals under a time-periodic magnetic field.

    Kar, Satyaki

    Journal of physics. Condensed matter : an Institute of Physics journal

    2021  Volume 33, Issue 22

    Abstract: Nodal line semimetals (NLSM) exhibit interesting quantum oscillation (QO) characteristics when acted upon by a strong magnetic field. We study the combined effect of strong direct and alternating magnetic field, perpendicular to the nodal plane in an ... ...

    Abstract Nodal line semimetals (NLSM) exhibit interesting quantum oscillation (QO) characteristics when acted upon by a strong magnetic field. We study the combined effect of strong direct and alternating magnetic field, perpendicular to the nodal plane in an untilted NLSM in order to probe the behavior of the low lying Landau level states that can periodically become gapless for suitably chosen field parameters. The oscillatory field variation, as opposed to a steady one, has interesting impact on the QO phenomena with the Landau tubes crossing the Fermi surface extremally two times per cycle. Furthermore, the low energy modes can witness Landau-Zener like transitions between valence and conduction band providing further routes to conduction. We discuss such transition phenomena following the framework of adiabatic-impulse approximation for slow quenches. Next we also investigate the effect of oscillating magnetic field acting parallel to the nodal loop where topologically nontrivial magnetic oscillations at low energies can be witnessed. Therefore, with proper parameters chosen, one can engineer topological transitions to occur periodically in such systems as the oscillating field is swept through its cycles.
    Language English
    Publishing date 2021-05-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/abe8a2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Protracted molecular dynamics and secondary structure introspection to identify dual-target inhibitors of Nipah virus exerting approved small molecules repurposing.

    Yang, Siyun / Kar, Supratik

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 3696

    Abstract: Nipah virus (NiV), with its significantly higher mortality rate compared to COVID-19, presents a looming threat as a potential next pandemic, particularly if constant mutations of NiV increase its transmissibility and transmission. Considering the ... ...

    Abstract Nipah virus (NiV), with its significantly higher mortality rate compared to COVID-19, presents a looming threat as a potential next pandemic, particularly if constant mutations of NiV increase its transmissibility and transmission. Considering the importance of preventing the facilitation of the virus entry into host cells averting the process of assembly forming the viral envelope, and encapsulating the nucleocapsid, it is crucial to take the Nipah attachment glycoprotein-human ephrin-B2 and matrix protein as dual targets. Repurposing approved small molecules in drug development is a strategic choice, as it leverages molecules with known safety profiles, accelerating the path to finding effective treatments against NiV. The approved small molecules from DrugBank were used for repurposing and were subjected to extra precision docking followed by absorption, distribution, metabolism, excretion, and toxicity (ADMET) profiling. The 4 best molecules were selected for 500 ns molecular dynamics (MD) simulation followed by Molecular mechanics with generalized Born and surface area solvation (MM-GBSA). Further, the free energy landscape, the principal component analysis followed by the defined secondary structure of proteins analysis were introspected. The inclusive analysis proposed that Iotrolan (DB09487) and Iodixanol (DB01249) are effective dual inhibitors, while Rutin (DB01698) and Lactitol (DB12942) were found to actively target the matrix protein only.
    MeSH term(s) Humans ; Nipah Virus/genetics ; Molecular Dynamics Simulation ; Drug Repositioning ; Protein Structure, Secondary ; COVID-19 ; Molecular Docking Simulation
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-54281-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Interlinked bi-stable switches govern the cell fate commitment of embryonic stem cells.

    Giri, Amitava / Kar, Sandip

    FEBS letters

    2024  Volume 598, Issue 8, Page(s) 915–934

    Abstract: The development of embryonic stem (ES) cells to extraembryonic trophectoderm and primitive endoderm lineages manifests distinct steady-state expression patterns of two key transcription factors-Oct4 and Nanog. How dynamically such kind of steady-state ... ...

    Abstract The development of embryonic stem (ES) cells to extraembryonic trophectoderm and primitive endoderm lineages manifests distinct steady-state expression patterns of two key transcription factors-Oct4 and Nanog. How dynamically such kind of steady-state expressions are maintained remains elusive. Herein, we demonstrate that steady-state dynamics involving two bistable switches which are interlinked via a stepwise (Oct4) and a mushroom-like (Nanog) manner orchestrate the fate specification of ES cells. Our hypothesis qualitatively reconciles various experimental observations and elucidates how different feedback and feedforward motifs orchestrate the extraembryonic development and stemness maintenance of ES cells. Importantly, the model predicts strategies to optimize the dynamics of self-renewal and differentiation of embryonic stem cells that may have therapeutic relevance in the future.
    MeSH term(s) Cell Differentiation ; Nanog Homeobox Protein/metabolism ; Nanog Homeobox Protein/genetics ; Animals ; Octamer Transcription Factor-3/metabolism ; Octamer Transcription Factor-3/genetics ; Embryonic Stem Cells/metabolism ; Embryonic Stem Cells/cytology ; Mice ; Cell Lineage/genetics ; Models, Biological ; Homeodomain Proteins/metabolism ; Homeodomain Proteins/genetics ; Gene Expression Regulation, Developmental ; Mouse Embryonic Stem Cells/metabolism ; Mouse Embryonic Stem Cells/cytology
    Chemical Substances Nanog Homeobox Protein ; Octamer Transcription Factor-3 ; Homeodomain Proteins ; Nanog protein, mouse ; Pou5f1 protein, mouse
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Research Support, Non-U.S. Gov't ; Journal Article
    ZDB-ID 212746-5
    ISSN 1873-3468 ; 0014-5793
    ISSN (online) 1873-3468
    ISSN 0014-5793
    DOI 10.1002/1873-3468.14832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Left atrial appendage closure

    Saw, Jacqueline / Kar, Saibal / Price, Matthew J.

    mechanical approaches to stroke prevention in atrial fibrillation

    (Contemporary cardiology)

    2016  

    Author's details Jacqueline Saw ; Saibal Kar ; Matthew J. Price ed
    Series title Contemporary cardiology
    Keywords left atrial appendage closure ; atrial fibrillation ; thromboembolic prevention ; WATCHMAN device ; Amplatzer Cardiac Plug ; LARIAT device
    Language English
    Size XI, 300 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018818806
    ISBN 978-3-319-16279-9 ; 978-3-319-16280-5 ; 3-319-16279-9 ; 3-319-16280-2
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Elevated Lipoprotein A in South Asians and the Associated Risk of Cardiovascular Disease: A Systematic Review.

    Kar, Subrata

    Current problems in cardiology

    2020  Volume 46, Issue 3, Page(s) 100581

    Abstract: Background: South Asians have a premature risk of cardiovascular disease and increased lipoprotein A which enhances their risk.: Methods: This systematic review evaluates the role of elevated lipoprotein A in cardiovascular disease risk for South ... ...

    Abstract Background: South Asians have a premature risk of cardiovascular disease and increased lipoprotein A which enhances their risk.
    Methods: This systematic review evaluates the role of elevated lipoprotein A in cardiovascular disease risk for South Asians. It discusses the pathophysiology, clinical studies, and treatment of elevated lipoprotein A using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method.
    Results: A total of 72 articles was incorporated which consisted of clinical studies, case-control and cohort studies, meta-analysis, reviews, and editorials. Cardiovascular disease and myocardial infarction occurs prematurely in South Asians, which is further enhanced with an elevated lipoprotein A.
    Conclusions: South Asians with an elevated lipoprotein A have an increased risk of coronary artery disease so they should have early enactment of lifestyle modification and aggressive medical management.
    MeSH term(s) Asian Continental Ancestry Group ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/metabolism ; Humans ; Lipoprotein(a)/metabolism ; Myocardial Infarction/drug therapy ; Myocardial Infarction/metabolism ; Randomized Controlled Trials as Topic ; Risk Factors
    Chemical Substances Lipoprotein(a)
    Language English
    Publishing date 2020-03-19
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2020.100581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Soft ideals of soft ternary semigroups.

    Kar, S / Dutta, I

    Heliyon

    2021  Volume 7, Issue 6, Page(s) e07330

    Abstract: In this paper, we introduce the notions of certain classes of soft ideals in soft ternary semigroups and study some inter-relations between different types of soft ideals in a soft ternary semigroup. We also characterize completely regular soft ternary ... ...

    Abstract In this paper, we introduce the notions of certain classes of soft ideals in soft ternary semigroups and study some inter-relations between different types of soft ideals in a soft ternary semigroup. We also characterize completely regular soft ternary semigroups with the help of these soft ideals of soft ternary semigroups.
    Language English
    Publishing date 2021-06-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2021.e07330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Remarkable enhancement of the adsorption and diffusion performance of alkali ions in two-dimensional (2D) transition metal oxide monolayers via Ru-doping.

    Sahoo, Shubham / Kumari, P / Som, Narayan N / Kar, S / Ahuja, Rajeev / Ray, S J

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4371

    Abstract: Transition metal oxides (TMO) are the preferred materials for metal ion battery cathodes because of their high redox potentials and good metal-ion intercalation capacity, which serve as an outstanding replacement for layered sulphide. In this work, using ...

    Abstract Transition metal oxides (TMO) are the preferred materials for metal ion battery cathodes because of their high redox potentials and good metal-ion intercalation capacity, which serve as an outstanding replacement for layered sulphide. In this work, using first-principles calculations based on Density functional theory approach, we explored the structural and electronic properties which comprise of adsorption and diffusion behaviour along with the analysis of voltage profile and storage capacity of Ru doped two-dimensional transition metal oxide [Formula: see text], [Formula: see text], and [Formula: see text] monolayers. The adsorption of alkali ions (Li, Na) to the surface of TMOs is strengthened by Ru-atom doping. Ru doping enhanced the adsorption energy of Li/Na-ion by 25%/11% for [Formula: see text], 8%/13% for [Formula: see text], and 10%/11% [Formula: see text] respectively. The open circuit voltage (OCV) also increases due to the high adsorption capacity of doped Monolayers. Ru doping makes the semiconducting TMOs conduct, which is suitable for battery application. As alkali ion moves closer to the dopant site, the adsorption energy increases. When alkali ions are close to the vicinity of doping site, their diffusion barrier decrease and rises as they go further away. Our current findings will be useful in finding ways to improve the storage performance of 2D oxide materials for application in energy harvesting and green energy architecture.
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-53966-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Soft ideals of soft ternary semigroups

    Kar, S. / Dutta, I.

    Heliyon. 2021 June, v. 7, no. 6 p.e07330-

    2021  

    Abstract: In this paper, we introduce the notions of certain classes of soft ideals in soft ternary semigroups and study some inter-relations between different types of soft ideals in a soft ternary semigroup. We also characterize completely regular soft ternary ... ...

    Abstract In this paper, we introduce the notions of certain classes of soft ideals in soft ternary semigroups and study some inter-relations between different types of soft ideals in a soft ternary semigroup. We also characterize completely regular soft ternary semigroups with the help of these soft ideals of soft ternary semigroups.
    Keywords classification ; data analysis ; mathematical models ; mathematical theory ; Soft ternary semigroup ; Soft prime ideal ; Soft semiprime ideal ; Soft irreducible ideal ; Soft bi-ideal ; Soft prime bi-ideal ; Soft semiprime bi-ideal ; Soft completely regular ternary semigroup
    Language English
    Dates of publication 2021-06
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2021.e07330
    Database NAL-Catalogue (AGRICOLA)

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