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Article ; Online: Reponse to Letter to The Editor: Regarding: Evaluation of vaccination status of health care workers for recommended vaccines and their acceptance of SARS-CoV-2 vaccines.

Oygar, Pembe Derin / Kara, Ates

2022 Volume 18, Issue 6, Page(s) 2106748

MeSH term(s)	Humans ; COVID-19 Vaccines ; COVID-19/prevention & control ; SARS-CoV-2 ; Vaccines ; Health Personnel ; Vaccination
Chemical Substances	COVID-19 Vaccines ; Vaccines
Language	English
Publishing date	2022-08-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2664176-8
ISSN	2164-554X ; 2164-5515
ISSN (online)	2164-554X
ISSN	2164-5515
DOI	10.1080/21645515.2022.2106748
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Article: Bağışıklama ve Aşı ile Ílgili Sorular ve Kısa Cevaplar: Journal of Pediatric Infection

Kara, Ateş

Cocuk Enfeksiyon Dergisi

Abstract: Bugüne kadar ülkemizde rutin olarak ilköğretim birinci sınıfta, okullarda yapılan difteri-tetanos-aselüler boğmaca ve inaktif polio (DaBT-IPA) hatırlatma aşı dozu ile kızamık-kızamıkçık-kabakulak hatırlatma aşı dozu, aile hekimliğinde ve 48 ayda ... ...

Abstract	Bugüne kadar ülkemizde rutin olarak ilköğretim birinci sınıfta, okullarda yapılan difteri-tetanos-aselüler boğmaca ve inaktif polio (DaBT-IPA) hatırlatma aşı dozu ile kızamık-kızamıkçık-kabakulak hatırlatma aşı dozu, aile hekimliğinde ve 48 ayda uygulanacak Çok kısa bir cevap ile, bağışıklama hizmetleri;rutin aşı takvimimizin uygulanması, gebe aşılaması, yetişkin aşılaması-risk grubu aşılaması, koruyucu hizmetlerin temelidir ve salgın döneminde de aksatılmadan devam etmesi sağlanmalıdır Yazışma Adresi/Correspondence Address Ateş Kara Hacettepe Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Enfeksiyon Hastalıkları Bilim Dalı, Ankara, Türkiye E-mail: ateskara@hacettepe edu tr Geliş Tarihi: 29 06 2020 Kabul Tarihi: 30 06 2020 Çevrimiçi Yayın Tarihi: 04 08 2020 ©Telif Hakkı 2020 Çocuk Enfeksiyon Hastalıkları ve Bağışıklama Derneği
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #826895
Database	COVID19

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Article ; Online: Global surveillance, travel, and trade during a pandemic

Çetin, Ceren / Kara, Ateş

Turkish journal of medical sciences

2020 Volume 50, Issue SI-1, Page(s) 527–533

Abstract: Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still ... ...

Abstract	Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still currently not always possible. Maybe the most important factor for this is the increasing frequency of traveling. Increasing airline traveling rate also increases the rate of spread. Global organizations like the World Health Organization and United Nations are trying to play a supreme role over the countries. Pandemics do not have borders; therefore, efforts should be given globally, definition of pandemic should be established as soon as possible, and protective measures should be shared with countries. If these are not done, severe health consequences and serious economic problems are inevitable.
MeSH term(s)	Global Health ; Humans ; Influenza, Human/epidemiology ; Pandemics ; Population Surveillance/methods ; Seasons ; Travel/trends
Keywords	covid19
Language	English
Publishing date	2020-04-21
Publishing country	Turkey
Document type	Journal Article ; Review
ZDB-ID	1183461-4
ISSN	1303-6165 ; 1300-0144
ISSN (online)	1303-6165
ISSN	1300-0144
DOI	10.3906/sag-2004-175
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Article ; Online: Multisystem inflammatory syndrome in children

Hançerli Törün, Selda / Yilmaz Çiftdoğan, Dilek / Kara, Ateş

Turkish journal of medical sciences

2021 Volume 51, Issue SI-1, Page(s) 3273–3283

Abstract: As the COVID-19 pandemic continues, children can be infected with the virus that causes COVID-19. Clinical symptoms of children with COVID from China, where the disease was first reported, generally were less severe than adults. However, at the end of ... ...

Abstract	As the COVID-19 pandemic continues, children can be infected with the virus that causes COVID-19. Clinical symptoms of children with COVID from China, where the disease was first reported, generally were less severe than adults. However, at the end of April 2020 in Europe, it was observed that some children with SARS-CoV-2 infection developed fever, abdominal pain, shock, myocardial insufficiency and they needed to be taken care of in intensive care unit. This new disease has been called multisystem inflammatory syndrome in children (MIS-C). Although the pathogenesis of MIS-C is unclear, it progresses with signs of multiorgan involvement as a result of uncontrolled inflammation of the immune system and even causes death. Therefore, the diagnosis and treatment of patients with MIS-C should be managed quickly. In this review, the pathophysiology, clinical and laboratory findings, diagnostic methods, and treatment regimens of MIS-C were discussed.
MeSH term(s)	COVID-19/complications ; COVID-19/epidemiology ; Child ; Humans ; Pandemics ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome
Language	English
Publishing date	2021-12-17
Publishing country	Turkey
Document type	Journal Article ; Review
ZDB-ID	1183461-4
ISSN	1303-6165 ; 1300-0144
ISSN (online)	1303-6165
ISSN	1300-0144
DOI	10.3906/sag-2105-342
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Article ; Online: Analysis of participant-reported adverse events following the first dose of inactivated SARS-Cov-2 vaccine (TURKOVAC™) through telephone survey in Türkiye.

Kara, Ateş / Coskun, Aslihan / Temel, Fehminaz / Özelci, Pervin / Topal, Selmur / Ateş, Ihsan

Annals of medicine

2023 Volume 55, Issue 1, Page(s) 1070–1079

Abstract: Background/objective(s)/introduction: TURKOVAC™ is a whole-virion inactivated COVID-19 vaccine, which was developed and recently granted emergency use authorization (conditional marketing authorization) in Türkiye. The objective of this study is to ... ...

Abstract	Background/objective(s)/introduction: TURKOVAC™ is a whole-virion inactivated COVID-19 vaccine, which was developed and recently granted emergency use authorization (conditional marketing authorization) in Türkiye. The objective of this study is to assess the spectrum and the distribution of adverse events reported following the administration of the first 150,000 doses as primary and booster vaccine doses in 22 state hospitals of 17 provinces in Türkiye. Patients/materials and methods: In this cohort study, a verbal survey was conducted Results: Thirty-six-point-six percent of the participants on the 3rd day and 22.5% of the participants on the 7th day reported any adverse event following the first dose of the vaccine. On both follow-up days, the most commonly reported (29.7% for Day 3 and 13.1% for Day 7) adverse events were on the injection site. Among the local adverse events, the most frequently reported one was the pain on the injection site (27.9% for Day 3 and 12.4% for Day 7), induration (4.8% for Day 3 and 2.7% for Day 7) and swelling (3.5% for Day 3 and 2.0% for Day 7). Fatigue/weakness (9.6% for Day 3 and 8.3% for Day 7) and headache (7.9% for Day 3 and 8.0% for Day 7) were the most frequent systemic adverse events. Younger age, vaccine dose, and female sex were associated with having any adverse event and pain (on the injection site). Female sex was associated with more swelling (on the injection site), induration (on the injection site), fever, and a higher impact on daily living. Conclusion(s): In this study, we conducted a rapid assessment of adverse events following the first dose of the TURKOVAC vaccine. The vaccine appears to have a good safety profile in the first 7 days following vaccination. Younger age, vaccine dose, and female sex are associated with any adverse event and pain (on the injection site). These results present valuable information for the community and may contribute to increasing vaccine confidence.KEY MESSAGESAs a whole-virion inactivated SARS-CoV-2 vaccine, the TURKOVAC™ vaccine, which has a favorable safety profile, can be an alternative to other COVID-19 vaccines including mRNA and viral vector vaccines.
MeSH term(s)	Female ; Humans ; Antibodies, Viral ; Cohort Studies ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Pain ; SARS-CoV-2 ; Telephone
Chemical Substances	Antibodies, Viral ; COVID-19 Vaccines ; TURKOVAC
Language	English
Publishing date	2023-03-11
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1004226-x
ISSN	1365-2060 ; 1651-2219 ; 0785-3890 ; 1743-1387
ISSN (online)	1365-2060 ; 1651-2219
ISSN	0785-3890 ; 1743-1387
DOI	10.1080/07853890.2023.2183985
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Article: Self-Reported Allergic Adverse Events Following Inactivated SARS-CoV-2 Vaccine (TURKOVAC™) among General and High-Risk Population.

Kara, Ateş / Coskun, Aslihan / Temel, Fehminaz / Özelci, Pervin / Topal, Selmur / Ates, İhsan

Vaccines

2023 Volume 11, Issue 2

Abstract: TURKOVAC™ is a whole-virion inactivated COVID-19 vaccine which was developed and granted emergency use and conditional marketing authorization in December 2021 in Türkiye. The objective of this study is to assess the distribution and the severity of ... ...

Abstract	TURKOVAC™ is a whole-virion inactivated COVID-19 vaccine which was developed and granted emergency use and conditional marketing authorization in December 2021 in Türkiye. The objective of this study is to assess the distribution and the severity of allergic adverse events following the administration of the vaccine as the primary or the booster dose in 15 provinces in Türkiye. In this cohort study, between February and May 2022, in the selected 15 provinces having an adequate number of health care personnel in the community health centers to conduct the study, 32,300 people having the first, the second, or the booster dose of the vaccine were invited to the survey. A total of 29,584 people voluntarily agreed to participate to the survey and were given a structured questionnaire after a minimum of 10 days following the vaccination. In our study, only 0.5% of the participants (142 persons) reported to experience any allergic reaction, and 12 of them (8.5%) reported to be given medical treatment in a health center. Male predominance (55.6%) was observed among participants reported to experience any allergic reaction. No hospitalization was recorded. Of the participants, 4.4% (1315 people) reported to have a history of allergy. The most reported allergens were drugs. Among the participants without a known history of allergy (
Language	English
Publishing date	2023-02-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines11020437
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Article: Global surveillance, travel, and trade during a pandemic

Çetin, Ceren / Kara, Ates

Turk J Med Sci

Abstract	Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still currently not always possible. Maybe the most important factor for this is the increasing frequency of traveling. Increasing airline traveling rate also increases the rate of spread. Global organizations like the World Health Organization and United Nations are trying to play a supreme role over the countries. Pandemics do not have borders; therefore, efforts should be given globally, definition of pandemic should be established as soon as possible, and protective measures should be shared with countries. If these are not done, severe health consequences and serious economic problems are inevitable.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #71830
Database	COVID19

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Article ; Online: Evaluation of medication errors in pediatric patients using antibiotics.

Özdemir, Nesligül / Kara, Emre / Büyükçam, Ayşe / Aykaç, Kübra / Çeliker, Ayçe / Demirkan, Kutay / Kara, Ateş

The Turkish journal of pediatrics

2022 Volume 63, Issue 6, Page(s) 970–977

Abstract: Background: Medication errors are frequently seen in pediatric patients. Medication error studies on pediatric cases were found to not only be limited but also the collaboration of clinical pharmacists and physicians on this topic was not published in ... ...

Abstract	Background: Medication errors are frequently seen in pediatric patients. Medication error studies on pediatric cases were found to not only be limited but also the collaboration of clinical pharmacists and physicians on this topic was not published in Turkey. This study aimed to identify drug-related problems, especially in antibiotics. Methods: This study was a point prevalence study with pediatric inpatients that used at least one antibiotic at a pediatric tertiary care reference hospital on November 16, 2016. Medications of patients were evaluated by clinical pharmacists in terms of drug-related problems and by physicians in terms of correct indications. Results: Eighty-nine hospitalized patients were using antibiotics at the time of the study. The median age was 42 months (range: 1-226 months), and 49 (55.1%) of the patients were male. Clinical pharmacists detected a total of 210 potential drug-drug interactions in 46 (51.7%) patients. Approximately 48.5% of the patients in pediatric wards and 52.4% of the patients in surgical wards had at least one potential drug-drug interaction. A total of 39 medication errors were identified in 36 patients` drug orders. Most of the errors (51.3%) were due to dosing and administration time errors (35.9%). The number of errors per patient in surgical services was higher (0.47) than the pediatric services (0.42). Forty-three percent of errors were antimicrobial-related, and 70.5% of them were classified as dosing errors. Conclusions: Evaluation of patients` drug usage by a clinical pharmacist in terms of drug-related problems such as drug interactions, side effects and prescribing errors leads to better pharmaceutical care.
MeSH term(s)	Adolescent ; Anti-Bacterial Agents/adverse effects ; Child ; Child, Preschool ; Drug-Related Side Effects and Adverse Reactions ; Female ; Humans ; Infant ; Male ; Medication Errors ; Pharmacists ; Pharmacy Service, Hospital
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2022-01-13
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	123487-0
ISSN	2791-6421 ; 0041-4301
ISSN (online)	2791-6421
ISSN	0041-4301
DOI	10.24953/turkjped.2021.06.004
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Article: The Present and Future Aspects of Life-Long Pertussis Prevention: Narrative Review with Regional Perspectives for Türkiye.

Pehlivan, Tamer / Dinleyici, Ener Cagri / Kara, Ateş / Kurugöl, Zafer / Tezer, Hasan / Aksakal, Nur Baran / Biri, Aydan / Azap, Alpay

Infectious diseases and therapy

2023 Volume 12, Issue 11, Page(s) 2495–2512

Abstract: Pertussis, caused by Bordetella pertussis, remains one of the most widespread, contagious, and vaccine-preventable diseases. It results in notable morbidity and mortality as well as severe medical, social, and economic burden. Despite high global vaccine ...

Abstract	Pertussis, caused by Bordetella pertussis, remains one of the most widespread, contagious, and vaccine-preventable diseases. It results in notable morbidity and mortality as well as severe medical, social, and economic burden. Despite high global vaccine coverage, pertussis continues to be a significant epidemiologic problem, with outbreak episodes every few years just as in the pre-vaccination era. In Türkiye, there is a lack of comprehensive data on the current burden of pertussis in different age and risk groups, leading to underdiagnosis and underreporting of the disease, especially in adults who are often not considered at risk. Available data from Türkiye also reveal inadequate levels of protective antibodies in preterm newborns, emphasizing the need for additional preventive measures. Authors stated that improving physician awareness of pertussis symptoms in patients with prolonged cough, increasing access to routine pertussis tests, and conducting surveillance studies would aid in accurate diagnosis and reporting in Türkiye. As the Turkish Ministry of Health Antenatal Care Management Guide suggests routine second and third pregnancy check-up visits at weeks 18-24 and 28-32 correspondingly, this period can be considered the ideal vaccination time for Türkiye. Introducing a booster dose of Tdap at around 10 years of age or during national military service would reduce transmission and protect susceptible individuals. Identifying individuals at high risk of severe pertussis and prioritizing them for a booster dose is also crucial in Türkiye. Enhancing surveillance systems, increasing healthcare professionals' awareness through training, and organizing catch-up visits for missed vaccinations during the COVID-19 pandemic are mentioned as additional strategies to improve pertussis prevention in Türkiye. This review focuses on the global and regional burden of pertussis and obstacles to effective prevention and evaluates existing strategies to achieve lifelong pertussis prevention. Literature and current strategies were also discussed from a Turkish national standpoint.
Language	English
Publishing date	2023-10-10
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2701611-0
ISSN	2193-6382 ; 2193-8229
ISSN (online)	2193-6382
ISSN	2193-8229
DOI	10.1007/s40121-023-00876-0
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Article ; Online: Knowledge, attitudes, and practices regarding vaccination among community pharmacists.

Ozdemir, Nesligul / Kara, Emre / Bayraktar-Ekincioglu, Aygin / Buyukcam, Ayse / Celiker, Ayce / Demirkan, Kutay / Kara, Ates

Primary health care research & development

2022 Volume 23, Page(s) e38

Abstract: Background: Healthcare professionals' vaccine recommendation is the most effective method to increase vaccination rates of the community. The vaccine counseling and recommendation behavior of pharmacists, who are among the easily accessible healthcare ... ...

Abstract	Background: Healthcare professionals' vaccine recommendation is the most effective method to increase vaccination rates of the community. The vaccine counseling and recommendation behavior of pharmacists, who are among the easily accessible healthcare professionals, are influenced by their knowledge and attitudes about vaccines. Aim: It was aimed to investigate community pharmacists' knowledge, attitudes, and practices regarding commonly used vaccines. Methods: A cross-sectional study was conducted as an online survey with a sample of 1100 community pharmacists in Turkey. Pharmacists were invited to participate in the study by phone calls. A structured survey, which consists of 40 questions to assess the knowledge, attitudes, and practices regarding vaccines, was sent to the e-mail addresses of pharmacists who volunteered to participate in the study. Findings: A total of 430 pharmacists completed the survey. Thirty percent of pharmacists had lack of knowledge about vaccination during pregnancy, whereas 52.2% and 31.4% of pharmacists believed that tetanus and influenza vaccines should be provided during pregnancy, respectively. Nearly 89% of pharmacists recommended vaccines to patients, mainly for influenza vaccine (83.9%). Only 31.5% of pharmacists had been vaccinated against influenza in the last season, whereas 50.5% had never been vaccinated. Pharmacists who had been vaccinated with influenza vaccine had a high rate of recommending influenza vaccines to the patients. Conclusion: The present study found that vaccination among pharmacists in Turkey and their knowledge on vaccination during pregnancy were low. Further education of pharmacists to improve their knowledge and attitudes toward vaccines is needed.
MeSH term(s)	Cross-Sectional Studies ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Influenza Vaccines ; Pharmacists/psychology ; Pregnancy ; Surveys and Questionnaires ; Vaccination/psychology
Chemical Substances	Influenza Vaccines
Language	English
Publishing date	2022-07-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2027892-5
ISSN	1477-1128 ; 1477-1128
ISSN (online)	1477-1128
ISSN	1477-1128
DOI	10.1017/S1463423622000330
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